Roles of aspartic acid-181 and serine-222 in intermediate formation and hydrolysis of the mammalian protein-tyrosine-phosphatase PTP1

Biochemistry

Volumn 36, Issue 15, 1997, Pages 4568-4575

  Lohse, Daniel L ^a   Denu, John M ^a,b   Santoro, Nicholas ^a   Dixon, Jack E ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; PROTEIN TYROSINE PHOSPHATASE; SERINE;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; CIRCULAR DICHROISM; CRYSTAL STRUCTURE; DEPHOSPHORYLATION; ENZYME ANALYSIS; ENZYME KINETICS; HYDROLYSIS; KINETICS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN TERTIARY STRUCTURE; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; ASPARTIC ACID; BINDING SITES; CATALYSIS; HUMANS; HYDROLYSIS; MUTAGENESIS, SITE-DIRECTED; PROTEIN-TYROSINE-PHOSPHATASE; RATS; SERINE; THIONUCLEOTIDES;

EID: 0030887994     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi963094r     Document Type: Article

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