Suppressed G-protein-coupled receptor kinase 2 activity protects female diabetic-mouse aorta against endothelial dysfunction

Acta Physiologica

Volumn 207, Issue 1, 2013, Pages 142-155

  Taguchi, K ^a   Matsumoto, T ^a   Kamata, K ^a   Kobayashi, T ^a  

^a HOSHI UNIVERSITY   (Japan)

Author keywords

Akt eNOS pathway; Clonidine; Endothelial dysfunction; GRK2; Sex difference; Type 2 diabetes

Indexed keywords

ALPHA ADRENERGIC RECEPTOR; BETA ARRESTIN; CLONIDINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; G PROTEIN COUPLED RECEPTOR KINASE 2; INSULIN; METHYL [(5 NITRO 2 FURYL)VINYL] 2 FUROATE; NITRIC OXIDE SYNTHASE; PHENYLEPHRINE; PROTEIN KINASE B; UNCLASSIFIED DRUG; VINYL DERIVATIVE;

ANIMAL MODEL; AORTA; ARTICLE; ENDOTHELIAL DYSFUNCTION; FEMALE; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; VASODILATATION; WESTERN BLOTTING;

ADRENERGIC ALPHA-2 RECEPTOR AGONISTS; ANIMALS; AORTA; CLONIDINE; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; ENDOTHELIUM, VASCULAR; FEMALE; G-PROTEIN-COUPLED RECEPTOR KINASE 2; MALE; MICE; MICE, INBRED ICR; NITRIC OXIDE SYNTHASE TYPE III; PHENYLEPHRINE; PROTO-ONCOGENE PROTEINS C-AKT; SEX CHARACTERISTICS; SIGNAL TRANSDUCTION; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS;

EID: 84870825756     PISSN: 17481708     EISSN: 17481716     Source Type: Journal    
DOI: 10.1111/j.1748-1716.2012.02473.x     Document Type: Article

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