Homocysteine effects classical pathway of GPCR down regulation: Gαq/11, Gα12/13, Gi/o

Molecular and Cellular Biochemistry

Volumn 321, Issue 1-2, 2009, Pages 1-8

  Vacek, T P ^a   Sen, U ^a   Tyagi, N ^a   Kumar, M ^a   Moshal, K S ^a   Passmore, J C ^a   Tyagi, Suresh C ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

Arrestin1; c Src; Desensitization; ERK1; G protein; GPCR; GRK2; Hcy; Heart failure; Homocysteine

Indexed keywords

BETA ARRESTIN 1; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR KINASE 2; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; HOMOCYSTEINE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 3; PERTUSSIS TOXIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DEPHOSPHORYLATION; ENDOTHELIUM CELL; ENZYME PHOSPHORYLATION; HEART FUNCTION; HYPOTHESIS; MICROVASCULATURE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RAT; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIUM; WESTERN BLOTTING;

ANIMALS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENDOTHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; G-PROTEIN-COUPLED RECEPTOR KINASE 2; GTP-BINDING PROTEIN ALPHA SUBUNITS, G12-G13; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HOMOCYSTEINE; RATS; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 58249143169     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-008-9904-4     Document Type: Article

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