Comparative pharmacokinetics of baicalin in normal and the type 2 diabetic rats after oral administration of the Radix scutellariae extract

Fitoterapia

Volumn 83, Issue 8, 2012, Pages 1435-1442

  Deng, Yuan Xiong ^a   Shi, Qun Zhi ^a   Chen, Bo ^a   Zhang, Xiao Jie ^a   Liu, Sheng Zi ^a   Qiu, Xi Min ^a  

^a HUNAN NORMAL UNIVERSITY   (China)

Author keywords

Baicalin; Pharmacokinetics; Presystemic metabolism; Scutellaria baicalensis Georgi; Type 2 diabetes

Indexed keywords

BAICALIN; BETA GLUCURONIDASE; PLANT EXTRACT; RADIX SCUTELLARIAE EXTRACT; STREPTOZOCIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG SYNTHESIS; ENZYME ACTIVITY; FECES ANALYSIS; INTESTINE MUCOSA; MALE; MAXIMUM PLASMA CONCENTRATION; MEDICINAL PLANT; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; RADIX SCUTELLARIAE; RAT; TIME TO MAXIMUM PLASMA CONCENTRATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; AREA UNDER CURVE; DIABETES MELLITUS, EXPERIMENTAL; FECES; FLAVANONES; FLAVONOIDS; GASTROINTESTINAL CONTENTS; GLUCURONIDASE; HALF-LIFE; MALE; MOLECULAR STRUCTURE; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; SCUTELLARIA BAICALENSIS;

RATTUS; SCUTELLARIA BAICALENSIS;

EID: 84870800270     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2012.08.007     Document Type: Article

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