-
1
-
-
33746377965
-
Contributions of beta-cell dysfunction and insulin resistance to the pathogenesis of impaired glucose tolerance and impaired fasting glucose
-
Abdul-Ghani MA, Tripathy D, DeFronzo RA (2006) Contributions of beta-cell dysfunction and insulin resistance to the pathogenesis of impaired glucose tolerance and impaired fasting glucose. Diabetes Care 29:1130-1139
-
(2006)
Diabetes Care
, vol.29
, pp. 1130-1139
-
-
Abdul-Ghani, M.A.1
Tripathy, D.2
DeFronzo, R.A.3
-
2
-
-
33750914846
-
Exendin 4 controls insulin production in rat islet beta cells predominantly by potentiation of glucose-stimulated proinsulin biosynthesis at the translational level
-
Alarcon C, Wicksteed B, Rhodes CJ (2006) Exendin 4 controls insulin production in rat islet beta cells predominantly by potentiation of glucose-stimulated proinsulin biosynthesis at the translational level. Diabetologia 49:2920-2929
-
(2006)
Diabetologia
, vol.49
, pp. 2920-2929
-
-
Alarcon, C.1
Wicksteed, B.2
Rhodes, C.J.3
-
3
-
-
0035821585
-
2+ channel expression at the cell surface by the small G-protein kir/Gem
-
2+ channel expression at the cell surface by the small G-protein kir/Gem. Nature 411:701-706
-
(2001)
Nature
, vol.411
, pp. 701-706
-
-
Beguin, P.1
Nagashima, K.2
Gonoi, T.3
Shibasaki, T.4
Takahashi, K.5
Kashima, Y.6
Ozaki, N.7
Geering, K.8
Iwanaga, T.9
Seino, S.10
-
4
-
-
0032768616
-
Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA binding activity in beta (INS-1)-cells
-
Buteau J, Roduit R, Susini S, Prentki M (1999) Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA binding activity in beta (INS-1)-cells. Diabetologia 42:856-864
-
(1999)
Diabetologia
, vol.42
, pp. 856-864
-
-
Buteau, J.1
Roduit, R.2
Susini, S.3
Prentki, M.4
-
5
-
-
9444228813
-
Prevention of type 2 diabetes: Insulin resistance and beta-cell function
-
Chiasson JL, Rabasa-Lhoret R (2004) Prevention of type 2 diabetes: insulin resistance and beta-cell function. Diabetes 53:S34-S38
-
(2004)
Diabetes
, vol.53
-
-
Chiasson, J.L.1
Rabasa-Lhoret, R.2
-
6
-
-
0037371744
-
Pharmacological agents that directly modulate insulin secretion
-
Doyle ME, Egan JM (2003) Pharmacological agents that directly modulate insulin secretion. Pharmacol Rev 55:105-131
-
(2003)
Pharmacol Rev
, vol.55
, pp. 105-131
-
-
Doyle, M.E.1
Egan, J.M.2
-
7
-
-
23844550012
-
A novel glucokinase activator modulates pancreatic islet and hepatocyte function
-
Efanov AM, Barrett DG, Brenner MB, Briggs SL, Delaunois A, Durbin JD, Giese U, Guo H, Radloff M, Gil GS, Sewing S, Wang Y, Weichert A, Zaliani A, Gromada J (2005) A novel glucokinase activator modulates pancreatic islet and hepatocyte function. Endocrinology 146:3696-3701
-
(2005)
Endocrinology
, vol.146
, pp. 3696-3701
-
-
Efanov, A.M.1
Barrett, D.G.2
Brenner, M.B.3
Briggs, S.L.4
Delaunois, A.5
Durbin, J.D.6
Giese, U.7
Guo, H.8
Radloff, M.9
Gil, G.S.10
Sewing, S.11
Wang, Y.12
Weichert, A.13
Zaliani, A.14
Gromada, J.15
-
8
-
-
0345618266
-
Upregulation of insulin receptor substrate-2 in pancreatic beta cells prevents diabetes
-
Hennige AM, Burks DJ, Ozcan U, Kulkarni RN, Ye J, Park S, Schubert M, Fisher TL, Dow MA, Leshan R, Zakaria M, Mossa-Basha M, White MF (2003) Upregulation of insulin receptor substrate-2 in pancreatic beta cells prevents diabetes. J Clin Invest 112:1521-1532
-
(2003)
J Clin Invest
, vol.112
, pp. 1521-1532
-
-
Hennige, A.M.1
Burks, D.J.2
Ozcan, U.3
Kulkarni, R.N.4
Ye, J.5
Park, S.6
Schubert, M.7
Fisher, T.L.8
Dow, M.A.9
Leshan, R.10
Zakaria, M.11
Mossa-Basha, M.12
White, M.F.13
-
9
-
-
33745970187
-
Exenatide: An incretin mimetic for the treatment of type 2 diabetes mellitus
-
Iltz JL, Baker DE, Setter SM, Campbell RK (2006) Exenatide: an incretin mimetic for the treatment of type 2 diabetes mellitus. Clin Ther 28:652-665
-
(2006)
Clin Ther
, vol.28
, pp. 652-665
-
-
Iltz, J.L.1
Baker, D.E.2
Setter, S.M.3
Campbell, R.K.4
-
10
-
-
0038339191
-
cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2
-
Jhala US, Canettieri G, Screaton RA, Kulkarni RN, Krajewski S, Reed J, Walker J, Lin X, White MF, Montminy M (2003) cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2. Genes Dev 17:1575-1580
-
(2003)
Genes Dev
, vol.17
, pp. 1575-1580
-
-
Jhala, U.S.1
Canettieri, G.2
Screaton, R.A.3
Kulkarni, R.N.4
Krajewski, S.5
Reed, J.6
Walker, J.7
Lin, X.8
White, M.F.9
Montminy, M.10
-
11
-
-
9644268967
-
PDX-I haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance
-
Kulkarni RN, Jhala US, Winnay JN, Krajewski S, Montminy M, Kahn CR (2004) PDX-I haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance. J Clin Invest 114:828-836
-
(2004)
J Clin Invest
, vol.114
, pp. 828-836
-
-
Kulkarni, R.N.1
Jhala, U.S.2
Winnay, J.N.3
Krajewski, S.4
Montminy, M.5
Kahn, C.R.6
-
12
-
-
0348048485
-
Reduced beta-cell mass and altered glucose sensing impair insulin-secretory function in betaIRKO mice
-
Otani K, Kulkarni RN, Baldwin AC, Krutzfeldt J, Ueki K, Stoffel M, Kahn CR, Polonsky KS (2004) Reduced beta-cell mass and altered glucose sensing impair insulin-secretory function in betaIRKO mice. Am J Physiol Endocrinol Metab 286:E41-E49
-
(2004)
Am J Physiol Endocrinol Metab
, vol.286
-
-
Otani, K.1
Kulkarni, R.N.2
Baldwin, A.C.3
Krutzfeldt, J.4
Ueki, K.5
Stoffel, M.6
Kahn, C.R.7
Polonsky, K.S.8
-
13
-
-
0029806065
-
Effects of dietary supplementation of lipophilic fraction from Panax ginseng on cGMP and cAMP in rat platelets and on blood coagulation
-
Park FU, Lee JH, Song YB, Park KH (1996) Effects of dietary supplementation of lipophilic fraction from Panax ginseng on cGMP and cAMP in rat platelets and on blood coagulation. Biol Pharm Bull 19:1434-1439
-
(1996)
Biol Pharm Bull
, vol.19
, pp. 1434-1439
-
-
Park, F.U.1
Lee, J.H.2
Song, Y.B.3
Park, K.H.4
-
14
-
-
11144305181
-
Possible role of ginsenoside Rb1 on regulation of rat liver triglycerides
-
Park KH, Shin HJ, Song YB, Hyun HC, Cho HJ, Ham HS, Yoo YB, Ko YC, Jun WT, Park HJ (2002) Possible role of ginsenoside Rb1 on regulation of rat liver triglycerides. Biol Pharm Bull 25:457-460
-
(2002)
Biol Pharm Bull
, vol.25
, pp. 457-460
-
-
Park, K.H.1
Shin, H.J.2
Song, Y.B.3
Hyun, H.C.4
Cho, H.J.5
Ham, H.S.6
Yoo, Y.B.7
Ko, Y.C.8
Jun, W.T.9
Park, H.J.10
-
15
-
-
33644850386
-
Exendin-4 promotes IRS2 signaling to mediate pancreatic beta-cell growth and function
-
Park S, Dong X, Fisher TL, Dunn SL, Omer AK, Weir G, White MF (2006) Exendin-4 promotes IRS2 signaling to mediate pancreatic beta-cell growth and function. J Biol Chem 281:1159-1168
-
(2006)
J Biol Chem
, vol.281
, pp. 1159-1168
-
-
Park, S.1
Dong, X.2
Fisher, T.L.3
Dunn, S.L.4
Omer, A.K.5
Weir, G.6
White, M.F.7
-
16
-
-
9444242665
-
Five stages of evolving beta-cell dysfunction during progression to diabetes
-
Weir GC, Bonner-Weir S (2004) Five stages of evolving beta-cell dysfunction during progression to diabetes. Diabetes 53:SI6-S21
-
(2004)
Diabetes
, vol.53
-
-
Weir, G.C.1
Bonner-Weir, S.2
-
17
-
-
0031918624
-
The IRS-signaling system: A network of docking proteins that mediate insulin action
-
White MF (1998) The IRS-signaling system: a network of docking proteins that mediate insulin action. Mol Cell Biochem 182:3-11
-
(1998)
Mol Cell Biochem
, vol.182
, pp. 3-11
-
-
White, M.F.1
-
18
-
-
0032567937
-
Disruption of IRS-2 causes type 2 diabetes in mice
-
Wither DJ, Gutierrez JS, Towery H, Burks DJ, Ren JM, Previs S, Zhang Y, Bernal D, Pons S, Shulman GI, Bonner-Weir S, White MF (1998) Disruption of IRS-2 causes type 2 diabetes in mice. Nature 391:900-904
-
(1998)
Nature
, vol.391
, pp. 900-904
-
-
Wither, D.J.1
Gutierrez, J.S.2
Towery, H.3
Burks, D.J.4
Ren, J.M.5
Previs, S.6
Zhang, Y.7
Bernal, D.8
Pons, S.9
Shulman, G.I.10
Bonner-Weir, S.11
White, M.F.12
-
19
-
-
33746701913
-
Ginsenoside Rb1 promotes neurotransmitter release by modulating phosphorylation of synapsins through a cAMP-dependent protein kinase, pathway
-
Xue JF, Liu ZJ, Hu JF, Chen H, Zhang JT, Chen NH (2006) Ginsenoside Rb1 promotes neurotransmitter release by modulating phosphorylation of synapsins through a cAMP-dependent protein kinase, pathway. Brain Res 1106:91-98
-
(2006)
Brain Res
, vol.1106
, pp. 91-98
-
-
Xue, J.F.1
Liu, Z.J.2
Hu, J.F.3
Chen, H.4
Zhang, J.T.5
Chen, N.H.6
-
20
-
-
4544370584
-
- secretion by the flavonoid baicalein in intestinal epithelia
-
- secretion by the flavonoid baicalein in intestinal epithelia. J Biol Chem 279:39310-39316
-
(2004)
J Biol Chem
, vol.279
, pp. 39310-39316
-
-
Yue, G.G.1
Yip, T.W.2
Huang, Y.3
Ko, W.H.4
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