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Volumn 6, Issue 11, 2012, Pages

A New Strategy Based on Smrho Protein Loaded Chitosan Nanoparticles as a Candidate Oral Vaccine against Schistosomiasis

Author keywords

[No Author keywords available]

Indexed keywords

ALGINIC ACID; CHITOSAN; GAMMA INTERFERON; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; INTERLEUKIN 10; NANOPARTICLE; SCHISTOSOMA VACCINE; SMRHO VACCINE; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

EID: 84870751323     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0001894     Document Type: Article
Times cited : (48)

References (60)
  • 1
    • 58149377487 scopus 로고    scopus 로고
    • Toward the elimination of schistosomiasis
    • King CH, (2009) Toward the elimination of schistosomiasis. New England Journal of Medicine 360: 106-109.
    • (2009) New England Journal of Medicine , vol.360 , pp. 106-109
    • King, C.H.1
  • 2
    • 84870729750 scopus 로고    scopus 로고
    • WHO WHO, N°115 Fs, editor
    • WHO WHO (2010) http://www.who.int/mediacentre/factsheets/fs115/en/index.html. In: N°115 Fs, editor.
    • (2010)
  • 3
    • 0037847426 scopus 로고    scopus 로고
    • Quantification of clinical morbidity associated with schistosome infection in sub-Saharan Africa
    • van der Werf MJ, de Vlas SJ, Brooker S, Looman CWN, Nagelkerke NJD, et al. (2003) Quantification of clinical morbidity associated with schistosome infection in sub-Saharan Africa. Acta Trop 86: 125-139.
    • (2003) Acta Trop , vol.86 , pp. 125-139
    • van der Werf, M.J.1    de Vlas, S.J.2    Brooker, S.3    Looman, C.W.N.4    Nagelkerke, N.J.D.5
  • 4
    • 0036216712 scopus 로고    scopus 로고
    • Chemotherapeutic approaches to schistosomes: current knowledge and outlook
    • Harder A, (2002) Chemotherapeutic approaches to schistosomes: current knowledge and outlook. Parasitology Research 88: 395-397.
    • (2002) Parasitology Research , vol.88 , pp. 395-397
    • Harder, A.1
  • 5
    • 0032030745 scopus 로고    scopus 로고
    • Schistosomiasis vaccine: research to development
    • Bergquist NR, Colley DG, (1998) Schistosomiasis vaccine: research to development. Parasitology Today 14: 99-104.
    • (1998) Parasitology Today , vol.14 , pp. 99-104
    • Bergquist, N.R.1    Colley, D.G.2
  • 6
    • 0036630087 scopus 로고    scopus 로고
    • Schistosomiasis: from risk assessment to control
    • Bergquist N, (2002) Schistosomiasis: from risk assessment to control. Trends in Parasitology 18: 309-314.
    • (2002) Trends in Parasitology , vol.18 , pp. 309-314
    • Bergquist, N.1
  • 8
    • 38549179418 scopus 로고    scopus 로고
    • Current status of vaccines for schistosomiasis
    • McManus DP, Loukas A, (2008) Current status of vaccines for schistosomiasis. Clin Microbiol Rev 21: 225-242.
    • (2008) Clin Microbiol Rev , vol.21 , pp. 225-242
    • McManus, D.P.1    Loukas, A.2
  • 9
    • 0031426202 scopus 로고    scopus 로고
    • Identification of Ras, MAP kinases, and a GAP protein in Schistosoma mansoni by immunoblotting and their putative involvement in male-female interaction
    • Schüssler P, Grevelding C, Kunz W, (1997) Identification of Ras, MAP kinases, and a GAP protein in Schistosoma mansoni by immunoblotting and their putative involvement in male-female interaction. Parasitology 115: 629-634.
    • (1997) Parasitology , vol.115 , pp. 629-634
    • Schüssler, P.1    Grevelding, C.2    Kunz, W.3
  • 12
    • 77951553269 scopus 로고    scopus 로고
    • Recent advances in mucosal delivery of vaccines: role of mucoadhesive/biodegradable polymeric carriers
    • Mishra N, Goyal AK, Tiwari S, Paliwal R, Paliwal SR, et al. (2010) Recent advances in mucosal delivery of vaccines: role of mucoadhesive/biodegradable polymeric carriers. Expert Opin Ther Pat 20: 661-679.
    • (2010) Expert Opin Ther Pat , vol.20 , pp. 661-679
    • Mishra, N.1    Goyal, A.K.2    Tiwari, S.3    Paliwal, R.4    Paliwal, S.R.5
  • 13
    • 0032862290 scopus 로고    scopus 로고
    • Potential of polymeric lamellar substrate particles (PLSP) as adjuvants for vaccines
    • Jabbal-Gill I, Lin W, Jenkins P, Watts P, Jimenez M, et al. (1999) Potential of polymeric lamellar substrate particles (PLSP) as adjuvants for vaccines. Vaccine 18: 238-250.
    • (1999) Vaccine , vol.18 , pp. 238-250
    • Jabbal-Gill, I.1    Lin, W.2    Jenkins, P.3    Watts, P.4    Jimenez, M.5
  • 14
    • 77954081810 scopus 로고    scopus 로고
    • Mucosal delivery of vaccines: role of mucoadhesive/biodegradable polymers
    • Garg N, Mangal S, Khambete H, Tyagi R, (2010) Mucosal delivery of vaccines: role of mucoadhesive/biodegradable polymers. Recent Pat Drug Deliv Formul 4: 114-128.
    • (2010) Recent Pat Drug Deliv Formul , vol.4 , pp. 114-128
    • Garg, N.1    Mangal, S.2    Khambete, H.3    Tyagi, R.4
  • 16
    • 33846857760 scopus 로고    scopus 로고
    • Chitosan solution enhances both humoral and cell-mediated immune responses to subcutaneous vaccination
    • Zaharoff DA, Rogers CJ, Hance KW, Schlom J, Greiner JW, (2007) Chitosan solution enhances both humoral and cell-mediated immune responses to subcutaneous vaccination. Vaccine 25: 2085-2094.
    • (2007) Vaccine , vol.25 , pp. 2085-2094
    • Zaharoff, D.A.1    Rogers, C.J.2    Hance, K.W.3    Schlom, J.4    Greiner, J.W.5
  • 17
    • 34247626970 scopus 로고    scopus 로고
    • Chitin induces accumulation in tissue of innate immune cells associated with allergy
    • Reese TA, Liang H-E, Tager AM, Luster AD, Van Rooijen N, et al. (2007) Chitin induces accumulation in tissue of innate immune cells associated with allergy. Nature 447: 92-96.
    • (2007) Nature , vol.447 , pp. 92-96
    • Reese, T.A.1    Liang, H.-E.2    Tager, A.M.3    Luster, A.D.4    van Rooijen, N.5
  • 18
    • 84857768885 scopus 로고    scopus 로고
    • Contribution of IL-33-activated type II innate lymphoid cells to pulmonary eosinophilia in intestinal nematode-infected mice
    • Yasuda K, Muto T, Kawagoe T, Matsumoto M, Sasaki Y, et al. (2012) Contribution of IL-33-activated type II innate lymphoid cells to pulmonary eosinophilia in intestinal nematode-infected mice. PNAS 109: 3451-3456.
    • (2012) PNAS , vol.109 , pp. 3451-3456
    • Yasuda, K.1    Muto, T.2    Kawagoe, T.3    Matsumoto, M.4    Sasaki, Y.5
  • 19
    • 22144431850 scopus 로고    scopus 로고
    • Local and systemic activity of the polysaccharide chitosan at lymphoid tissues after oral administration
    • Porporatto C, Bianco ID, Correa SG, (2005) Local and systemic activity of the polysaccharide chitosan at lymphoid tissues after oral administration. J Leuk Biol 78: 62-69.
    • (2005) J Leuk Biol , vol.78 , pp. 62-69
    • Porporatto, C.1    Bianco, I.D.2    Correa, S.G.3
  • 20
    • 0034833470 scopus 로고    scopus 로고
    • Th1 Adjuvant N-Acetyl-d-Glucosamine Polymer Up-Regulates Th1 Immunity but Down-Regulates Th2 Immunity against a Mycobacterial Protein (MPB-59) in Interleukin-10-Knockout and Wild-Type Mice
    • Shibata Y, Honda I, Justice JP, Van Scott MR, Nakamura RM, et al. (2001) Th1 Adjuvant N-Acetyl-d-Glucosamine Polymer Up-Regulates Th1 Immunity but Down-Regulates Th2 Immunity against a Mycobacterial Protein (MPB-59) in Interleukin-10-Knockout and Wild-Type Mice. Infect Immun 69: 6123-6130.
    • (2001) Infect Immun , vol.69 , pp. 6123-6130
    • Shibata, Y.1    Honda, I.2    Justice, J.P.3    van Scott, M.R.4    Nakamura, R.M.5
  • 21
    • 0034879035 scopus 로고    scopus 로고
    • Chitosan: some pharmaceutical and biological aspects - an update
    • Singla AK, Chawla M, (2001) Chitosan: some pharmaceutical and biological aspects- an update. J Pharm Pharmacol 53: 1047-1067.
    • (2001) J Pharm Pharmacol , vol.53 , pp. 1047-1067
    • Singla, A.K.1    Chawla, M.2
  • 22
    • 0036123018 scopus 로고    scopus 로고
    • The effect of chitosan and other polycations on tight junction permeability in the human intestinal Caco-2 cell line
    • Ranaldi G, Marigliano I, Vespignani I, Perozzi G, Sambuy Y, (2002) The effect of chitosan and other polycations on tight junction permeability in the human intestinal Caco-2 cell line. The Journal of Nutritional Biochemistry 13: 157-167.
    • (2002) The Journal of Nutritional Biochemistry , vol.13 , pp. 157-167
    • Ranaldi, G.1    Marigliano, I.2    Vespignani, I.3    Perozzi, G.4    Sambuy, Y.5
  • 23
    • 0035936972 scopus 로고    scopus 로고
    • Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency
    • Mao H, Roy K, Troung-Le VL, Janes KA, Lin KY, et al. (2001) Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency. J Control Release 70: 399-421.
    • (2001) J Control Release , vol.70 , pp. 399-421
    • Mao, H.1    Roy, K.2    Troung-Le, V.L.3    Janes, K.A.4    Lin, K.Y.5
  • 24
    • 21844435468 scopus 로고    scopus 로고
    • Preparation of coated nanoparticles for a new mucosal vaccine delivery system
    • Borges O, Borchard G, Verhoef J, de Sousa A, Junginger H, (2005) Preparation of coated nanoparticles for a new mucosal vaccine delivery system. Int J Pharm 299: 155-166.
    • (2005) Int J Pharm , vol.299 , pp. 155-166
    • Borges, O.1    Borchard, G.2    Verhoef, J.3    de Sousa, A.4    Junginger, H.5
  • 25
    • 33748131292 scopus 로고    scopus 로고
    • Uptake studies in rat peyer's patches, cytotoxicity and release studies of alginate coated chitosan nanoparticles for mucosal vaccination
    • Borges O, Cordeiro-da-Silva A, Romeijn SG, Amidi M, Sousa AD, et al. (2006) Uptake studies in rat peyer's patches, cytotoxicity and release studies of alginate coated chitosan nanoparticles for mucosal vaccination. J Control Release 114: 348-358.
    • (2006) J Control Release , vol.114 , pp. 348-358
    • Borges, O.1    Cordeiro-da-Silva, A.2    Romeijn, S.G.3    Amidi, M.4    Sousa, A.D.5
  • 26
    • 33644836224 scopus 로고    scopus 로고
    • Mucosal vaccines: the promise and the challenge
    • Neutra MR, Kozlowski PA, (2006) Mucosal vaccines: the promise and the challenge. Nat Rev Immunol 6: 148-158.
    • (2006) Nat Rev Immunol , vol.6 , pp. 148-158
    • Neutra, M.R.1    Kozlowski, P.A.2
  • 27
    • 0034746596 scopus 로고    scopus 로고
    • An infrared investigation in relation with chitin and chitosan characterization
    • Brugnerotto J, Lizardi J, Goycoolea F, Arguelles-Monal W, Desbrieres J, et al. (2001) An infrared investigation in relation with chitin and chitosan characterization. Polymer 42: 3569-3580.
    • (2001) Polymer , vol.42 , pp. 3569-3580
    • Brugnerotto, J.1    Lizardi, J.2    Goycoolea, F.3    Arguelles-Monal, W.4    Desbrieres, J.5
  • 30
    • 70349162856 scopus 로고    scopus 로고
    • Improving chitosan-mediated gene transfer by the introduction of intracellular buffering moieties into the chitosan backbone
    • Moreira C, Oliveira H, Pires LR, Simões S, Barbosa MA, et al. (2009) Improving chitosan-mediated gene transfer by the introduction of intracellular buffering moieties into the chitosan backbone. Acta Biomater 5: 2995-3006.
    • (2009) Acta Biomater , vol.5 , pp. 2995-3006
    • Moreira, C.1    Oliveira, H.2    Pires, L.R.3    Simões, S.4    Barbosa, M.A.5
  • 31
    • 84861034466 scopus 로고    scopus 로고
    • Oral Vaccination Based on DNA-Chitosan Nanoparticles against Schistosoma mansoni Infection
    • Oliveira C, Rezende C, Silva M, Borges O, Pêgo A, et al. (2012) Oral Vaccination Based on DNA-Chitosan Nanoparticles against Schistosoma mansoni Infection. TSWJ 2012: 11.
    • (2012) TSWJ , vol.2012 , pp. 11
    • Oliveira, C.1    Rezende, C.2    Silva, M.3    Borges, O.4    Pêgo, A.5
  • 32
    • 84864284393 scopus 로고    scopus 로고
    • Protective effect of rPb40 as an adjuvant for chemotherapy in experimental paracoccidioidomycosis
    • Fernandes V, Martins E, Boeloni J, Serakides R, Goes A, (2012) Protective effect of rPb40 as an adjuvant for chemotherapy in experimental paracoccidioidomycosis. Mycopathologia 174: 93-105.
    • (2012) Mycopathologia , vol.174 , pp. 93-105
    • Fernandes, V.1    Martins, E.2    Boeloni, J.3    Serakides, R.4    Goes, A.5
  • 33
    • 0013812695 scopus 로고
    • The infection of laboratory hosts with cercariae of Schistosoma mansoni and the recovery of the adult worms
    • Smithers SR, Terry RJ, (1965) The infection of laboratory hosts with cercariae of Schistosoma mansoni and the recovery of the adult worms. Parasitology 55: 695-700.
    • (1965) Parasitology , vol.55 , pp. 695-700
    • Smithers, S.R.1    Terry, R.J.2
  • 34
    • 0024378932 scopus 로고
    • Production and characterization of human monoclonal antibodies against Schistosoma mansoni
    • Goes AM, Rocha RS, Gazzinelli G, Doughty BL, (1989) Production and characterization of human monoclonal antibodies against Schistosoma mansoni. Parasite Immunology 11: 695-711.
    • (1989) Parasite Immunology , vol.11 , pp. 695-711
    • Goes, A.M.1    Rocha, R.S.2    Gazzinelli, G.3    Doughty, B.L.4
  • 35
    • 0141867753 scopus 로고    scopus 로고
    • Ultrasonication of chitosan and chitosan nanoparticles
    • Tang ESK, Huang M, Lim LY, (2003) Ultrasonication of chitosan and chitosan nanoparticles. Int J Pharm 265: 103-114.
    • (2003) Int J Pharm , vol.265 , pp. 103-114
    • Tang, E.S.K.1    Huang, M.2    Lim, L.Y.3
  • 36
    • 48949118085 scopus 로고    scopus 로고
    • Trick or Treat: The Role of Vaccines in Integrated Schistosomiasis Control
    • Bergquist R, Utzinger J, McManus DP, (2008) Trick or Treat: The Role of Vaccines in Integrated Schistosomiasis Control. PLoS Negl Trop Dis 2: e244.
    • (2008) PLoS Negl Trop Dis , vol.2
    • Bergquist, R.1    Utzinger, J.2    McManus, D.P.3
  • 37
    • 4644298613 scopus 로고    scopus 로고
    • Enteric Pathogens as Vaccine Vectors for Foreign Antigen Delivery
    • Kotton CN, Hohmann EL, (2004) Enteric Pathogens as Vaccine Vectors for Foreign Antigen Delivery. Infect Immun 72: 5535-5547.
    • (2004) Infect Immun , vol.72 , pp. 5535-5547
    • Kotton, C.N.1    Hohmann, E.L.2
  • 38
    • 0036010388 scopus 로고    scopus 로고
    • Blood protein adsorption onto chitosan
    • Benesch J, Tengvall P, (2002) Blood protein adsorption onto chitosan. Biomaterials 23: 2561-2568.
    • (2002) Biomaterials , vol.23 , pp. 2561-2568
    • Benesch, J.1    Tengvall, P.2
  • 39
    • 57849131157 scopus 로고    scopus 로고
    • Preparation of alginate coated chitosan microparticles for vaccine delivery
    • Li XY, Kong X, Shi S, Zheng X, Guo G, et al. (2008) Preparation of alginate coated chitosan microparticles for vaccine delivery. BMC Biotechnol 8: 89.
    • (2008) BMC Biotechnol , vol.8 , pp. 89
    • Li, X.Y.1    Kong, X.2    Shi, S.3    Zheng, X.4    Guo, G.5
  • 40
    • 4644328176 scopus 로고    scopus 로고
    • Novel approaches to vaccine delivery
    • O'Hagan DT, Rappuoli R, (2004) Novel approaches to vaccine delivery. Pharm Res 21: 1519-1530.
    • (2004) Pharm Res , vol.21 , pp. 1519-1530
    • O'Hagan, D.T.1    Rappuoli, R.2
  • 41
    • 80053313377 scopus 로고    scopus 로고
    • Recent advances of chitosan nanoparticles as drug carriers
    • Wang J, Zeng Z, Xiao R, Xie T, Zhou G, et al. (2011) Recent advances of chitosan nanoparticles as drug carriers. Int J Nanomedicine 6: 765-774.
    • (2011) Int J Nanomedicine , vol.6 , pp. 765-774
    • Wang, J.1    Zeng, Z.2    Xiao, R.3    Xie, T.4    Zhou, G.5
  • 42
    • 33747077486 scopus 로고    scopus 로고
    • Advances and potential applications of chitosan derivatives as mucoadhesive biomaterials in modern drug delivery
    • Chopra S, Mahdi S, Kaur J, Iqbal Z, Talegaonkar S, et al. (2006) Advances and potential applications of chitosan derivatives as mucoadhesive biomaterials in modern drug delivery. Journal of Pharmacy and Pharmacology 58: 1021-1032.
    • (2006) Journal of Pharmacy and Pharmacology , vol.58 , pp. 1021-1032
    • Chopra, S.1    Mahdi, S.2    Kaur, J.3    Iqbal, Z.4    Talegaonkar, S.5
  • 43
    • 27144541896 scopus 로고    scopus 로고
    • The potential of chitosan for the oral administration of peptides
    • Prego C, Torres D, Alonso MJ, (2005) The potential of chitosan for the oral administration of peptides. Expert Opinion on Drug Delivery 2: 843-854.
    • (2005) Expert Opinion on Drug Delivery , vol.2 , pp. 843-854
    • Prego, C.1    Torres, D.2    Alonso, M.J.3
  • 44
    • 0035839201 scopus 로고    scopus 로고
    • Chitosan-based nanoparticles for topical genetic immunization
    • Cui Z, Mumper R, (2001) Chitosan-based nanoparticles for topical genetic immunization. J Control Release 75: 409-419.
    • (2001) J Control Release , vol.75 , pp. 409-419
    • Cui, Z.1    Mumper, R.2
  • 45
    • 0037471396 scopus 로고    scopus 로고
    • Chitosan microparticles for mucosal vaccination against diphtheria: oral and nasal efficacy studies in mice
    • Lubben M, Kersten G, Fretz M, Beuvery C, Verhoef J, et al. (2003) Chitosan microparticles for mucosal vaccination against diphtheria: oral and nasal efficacy studies in mice. Vaccine 21: 1400-1408.
    • (2003) Vaccine , vol.21 , pp. 1400-1408
    • Lubben, M.1    Kersten, G.2    Fretz, M.3    Beuvery, C.4    Verhoef, J.5
  • 46
    • 0030891836 scopus 로고    scopus 로고
    • Orally administered microencapsulated reovirus can bypass suckled, neutralizing maternal antibody that inhibits active immunization of neonates
    • Periwal SB, Speaker TJ, Cebra JJ, (1997) Orally administered microencapsulated reovirus can bypass suckled, neutralizing maternal antibody that inhibits active immunization of neonates. J Virology 71: 2844-2850.
    • (1997) J Virology , vol.71 , pp. 2844-2850
    • Periwal, S.B.1    Speaker, T.J.2    Cebra, J.J.3
  • 48
    • 0027577416 scopus 로고
    • An influence of the structure of alginate on the chemotactic activity of macrophages and the antitumor activity
    • Fujihara M, Nagumo T, (1993) An influence of the structure of alginate on the chemotactic activity of macrophages and the antitumor activity. Carbohydrate Research 243: 211-216.
    • (1993) Carbohydrate Research , vol.243 , pp. 211-216
    • Fujihara, M.1    Nagumo, T.2
  • 49
    • 80052030876 scopus 로고    scopus 로고
    • Enhancing immunogenicity to PLGA microparticulate systems by incorporation of alginate and RGD-modified alginate
    • Mata E, Igartua M, Patarroyo M, Pedraz J, Hernández R, (2011) Enhancing immunogenicity to PLGA microparticulate systems by incorporation of alginate and RGD-modified alginate. Eur J Pharm Sci 44: 32-40.
    • (2011) Eur J Pharm Sci , vol.44 , pp. 32-40
    • Mata, E.1    Igartua, M.2    Patarroyo, M.3    Pedraz, J.4    Hernández, R.5
  • 50
    • 0029166483 scopus 로고
    • Cytokine regulation of granuloma formation in schistosomiasis
    • Wynn TA, Cheever AW, (1995) Cytokine regulation of granuloma formation in schistosomiasis. Curr Opin Immunol 7: 505-511.
    • (1995) Curr Opin Immunol , vol.7 , pp. 505-511
    • Wynn, T.A.1    Cheever, A.W.2
  • 51
    • 44749088349 scopus 로고    scopus 로고
    • Attenuating Regulatory T Cell Induction by TLR Agonists through Inhibition of p38 MAPK Signaling in Dendritic Cells Enhances Their Efficacy as Vaccine Adjuvants and Cancer Immunotherapeutics
    • Jarnicki AG, Conroy H, Brereton C, Donnelly G, Toomey D, et al. (2008) Attenuating Regulatory T Cell Induction by TLR Agonists through Inhibition of p38 MAPK Signaling in Dendritic Cells Enhances Their Efficacy as Vaccine Adjuvants and Cancer Immunotherapeutics. The Journal of Immunology 180: 3797-3806.
    • (2008) The Journal of Immunology , vol.180 , pp. 3797-3806
    • Jarnicki, A.G.1    Conroy, H.2    Brereton, C.3    Donnelly, G.4    Toomey, D.5
  • 52
    • 78649529316 scopus 로고    scopus 로고
    • Dual role of CpG as immune modulator and physical crosslinker in ovalbumin loaded N-trimethyl chitosan (TMC) nanoparticles for nasal vaccination
    • Slutter B, Jiskoot W, (2010) Dual role of CpG as immune modulator and physical crosslinker in ovalbumin loaded N-trimethyl chitosan (TMC) nanoparticles for nasal vaccination. J Control Release 148: 117-121.
    • (2010) J Control Release , vol.148 , pp. 117-121
    • Slutter, B.1    Jiskoot, W.2
  • 53
    • 77649198518 scopus 로고    scopus 로고
    • Chitins and Chitosans as Immunoadjuvants and Non-Allergenic Drug Carriers
    • Muzzarelli R, (2010) Chitins and Chitosans as Immunoadjuvants and Non-Allergenic Drug Carriers. Mar Drugs 8: 292-312.
    • (2010) Mar Drugs , vol.8 , pp. 292-312
    • Muzzarelli, R.1
  • 55
    • 0030450277 scopus 로고    scopus 로고
    • Development of an Antipathology Vaccine for Schistosomiasis
    • Wynn TA, (1996) Development of an Antipathology Vaccine for Schistosomiasis. Annals N Y Acad Sci 797: 191-195.
    • (1996) Annals N Y Acad Sci , vol.797 , pp. 191-195
    • Wynn, T.A.1
  • 56
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • Gordon S, (2003) Alternative activation of macrophages. Nat Rev Immunol 3: 23-35.
    • (2003) Nat Rev Immunol , vol.3 , pp. 23-35
    • Gordon, S.1
  • 57
    • 33745036694 scopus 로고    scopus 로고
    • Type 2 immunity is controlled by IL-4/IL-13 expression in hematopoietic non-eosinophil cells of the innate immune system
    • Voehringer D, Reese TA, Huang X, Shinkai K, Locksley RM, (2006) Type 2 immunity is controlled by IL-4/IL-13 expression in hematopoietic non-eosinophil cells of the innate immune system. The Journal of Experimental Medicine 203: 1435-1446.
    • (2006) The Journal of Experimental Medicine , vol.203 , pp. 1435-1446
    • Voehringer, D.1    Reese, T.A.2    Huang, X.3    Shinkai, K.4    Locksley, R.M.5
  • 58
    • 56149127705 scopus 로고    scopus 로고
    • TLR-2 and IL-17A in Chitin-Induced Macrophage Activation and Acute Inflammation
    • Da Silva CA, Hartl D, Liu W, Lee CG, Elias JA, (2008) TLR-2 and IL-17A in Chitin-Induced Macrophage Activation and Acute Inflammation. J Immunol 181: 4279-4286.
    • (2008) J Immunol , vol.181 , pp. 4279-4286
    • Da Silva, C.A.1    Hartl, D.2    Liu, W.3    Lee, C.G.4    Elias, J.A.5
  • 59
    • 2442717844 scopus 로고    scopus 로고
    • Alternative Macrophage Activation Is Essential for Survival during Schistosomiasis and Downmodulates T Helper 1 Responses and Immunopathology
    • Herbert DBR, Hölscher C, Mohrs M, Arendse B, Schwegmann A, et al. (2004) Alternative Macrophage Activation Is Essential for Survival during Schistosomiasis and Downmodulates T Helper 1 Responses and Immunopathology. Immunity 20: 623-635.
    • (2004) Immunity , vol.20 , pp. 623-635
    • Herbert, D.B.R.1    Hölscher, C.2    Mohrs, M.3    Arendse, B.4    Schwegmann, A.5
  • 60
    • 0032032365 scopus 로고    scopus 로고
    • Why Don't We Have a Schistosomiasis Vaccine?
    • Wilson RA, Coulson PS, (1998) Why Don't We Have a Schistosomiasis Vaccine? Parasitology Today 14: 97-99.
    • (1998) Parasitology Today , vol.14 , pp. 97-99
    • Wilson, R.A.1    Coulson, P.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.