메뉴 건너뛰기




Volumn 3 NOV, Issue , 2012, Pages

Group I metabotropic glutamate receptor-mediated gene transcription and implications for synaptic plasticity and diseases

Author keywords

CREB; FMRP; Fragile X syndrome; Gene transcription; Group I metabotropic glutamate receptors; Signal transduction; Synaptic plasticity

Indexed keywords

ACTIVITY REGULATED CYTOSKELETON ASSOCIATED PROTEIN; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; FRAGILE X MENTAL RETARDATION PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; METABOTROPIC RECEPTOR 1; MITOGEN ACTIVATED PROTEIN KINASE;

EID: 84870727469     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2012.00189     Document Type: Article
Times cited : (51)

References (112)
  • 1
    • 47549103906 scopus 로고    scopus 로고
    • c-Rel, an NF-kappaB family transcription factor, is required for hippocam-pal long-term synaptic plasticity and memory formation
    • Ahn, H. J., Hernandez, C. M., Leven-son, J. M., Lubin, F. D., Liou, H. C., and Sweatt, J. D. (2008). c-Rel, an NF-kappaB family transcription factor, is required for hippocam-pal long-term synaptic plasticity and memory formation. Learn. Mem.15, 539-549.
    • (2008) Learn. Mem. , vol.15 , pp. 539-549
    • Ahn, H.J.1    Hernandez, C.M.2    Leven-son, J.M.3    Lubin, F.D.4    Liou, H.C.5    Sweatt, J.D.6
  • 2
    • 79551663694 scopus 로고    scopus 로고
    • Activity-induced Notch signaling in neurons requires Arc/Arg3, 1 and is essential for synaptic plasticity in hippocampal networks
    • Alberi, L., Liu, S., Wang, Y., Badie, R., Smith-Hicks, C., Wu, J., et al. (2011). Activity-induced Notch signaling in neurons requires Arc/Arg3.1 and is essential for synaptic plasticity in hippocampal networks. Neuron 69, 437-444.
    • (2011) Neuron , vol.69 , pp. 437-444
    • Alberi, L.1    Liu, S.2    Wang, Y.3    Badie, R.4    Smith-Hicks, C.5    Wu, J.6
  • 3
    • 1642336232 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor activation regulates fragile X mental retardation protein and FMR1 mRNA localization differentially in dendrites and at synapses
    • Antar, L. N., Afroz, R., Dictenberg, J. B., Carroll, R. C., and Bassell, G. J. (2004). Metabotropic glutamate receptor activation regulates fragile X mental retardation protein and FMR1 mRNA localization differentially in dendrites and at synapses. J. Neurosci. 24, 2648-2655.
    • (2004) J. Neurosci. , vol.24 , pp. 2648-2655
    • Antar, L.N.1    Afroz, R.2    Dictenberg, J.B.3    Carroll, R.C.4    Bassell, G.J.5
  • 4
    • 60149095737 scopus 로고    scopus 로고
    • Metabotropic glu-tamate receptor-dependent long-term potentiation
    • Anwyl, R. (2009). Metabotropic glu-tamate receptor-dependent long-term potentiation. Neuropharmacol-ogy 56, 735-740.
    • (2009) Neuropharmacol-ogy , vol.56 , pp. 735-740
    • Anwyl, R.1
  • 5
    • 2342667386 scopus 로고    scopus 로고
    • Mitogen-and stress-activated protein kinase 1 mediates cAMP response element-binding protein phosphorylation and activation by neurotrophins
    • Arthur, J. S., Fong, A. L., Dwyer, J. M., Davare, M., Reese, E., Obri-etan, K., et al. (2004). Mitogen-and stress-activated protein kinase 1 mediates cAMP response element-binding protein phosphorylation and activation by neurotrophins. J. Neurosci. 24, 4324-4332.
    • (2004) J. Neurosci. , vol.24 , pp. 4324-4332
    • Arthur, J.S.1    Fong, A.L.2    Dwyer, J.M.3    Davare, M.4    Reese, E.5    Obri-etan, K.6
  • 6
    • 0035896373 scopus 로고    scopus 로고
    • Tetanic stimulation and metabotropic glutamate receptor agonists modify synaptic responses and protein kinase activity in rat auditory cortex
    • Bandrowski, A.E., Ashe, J.H., and Crawford, C. A. (2001). Tetanic stimulation and metabotropic glutamate receptor agonists modify synaptic responses and protein kinase activity in rat auditory cortex. Brain Res. 894, 218-232.
    • (2001) Brain Res , vol.894 , pp. 218-232
    • Bandrowski, A.E.1    Ashe, J.H.2    Crawford, C.A.3
  • 7
    • 33845794324 scopus 로고    scopus 로고
    • Synapticmechanismsofsyn-chronized gamma oscillations in inhibitory interneuron networks
    • Bartos, M., Vida, I., and Jonas, P. (2007). Synapticmechanismsofsyn-chronized gamma oscillations in inhibitory interneuron networks. Nat. Rev. Neurosci. 8, 45-56.
    • (2007) Nat. Rev. Neurosci. , vol.8 , pp. 45-56
    • Bartos, M.1    Vida, I.2    Jonas, P.3
  • 8
    • 53849110899 scopus 로고    scopus 로고
    • Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function
    • Bassell, G. J., and Warren, S. T. (2008). Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function. Neuron 60, 201-214.
    • (2008) Neuron , vol.60 , pp. 201-214
    • Bassell, G.J.1    Warren, S.T.2
  • 9
    • 3042647610 scopus 로고    scopus 로고
    • The mGluR theory of fragile X mental retardation
    • Bear, M. F., Huber, K. M., and Warren, S. T. (2004). The mGluR theory of fragile X mental retardation. Trends Neurosci. 27, 370-377.
    • (2004) Trends Neurosci , vol.27 , pp. 370-377
    • Bear, M.F.1    Huber, K.M.2    Warren, S.T.3
  • 11
    • 84866143256 scopus 로고    scopus 로고
    • mGluR-dependent synaptic plasticity in drug-seeking
    • doi:10.3389/fphar.2012.00159
    • Bellone, C., and Mameli, M. (2012). mGluR-dependent synaptic plasticity in drug-seeking. Front. Pharmacol. 3:159. doi:10.3389/fphar.2012.00159
    • (2012) Front. Pharmacol , vol.3 , pp. 159
    • Bellone, C.1    Mameli, M.2
  • 12
    • 84862637069 scopus 로고    scopus 로고
    • The pathophysiology of fragile X (and what it teaches us about synapses)
    • Bhakar, A. L., Dolen, G., and Bear, M. F. (2012). The pathophysiology of fragile X (and what it teaches us about synapses). Annu. Rev. Neu-rosci. 35, 417-443.
    • (2012) Annu. Rev. Neu-rosci. , vol.35 , pp. 417-443
    • Bhakar, A.L.1    Dolen, G.2    Bear, M.F.3
  • 13
    • 79955709006 scopus 로고    scopus 로고
    • A requirement for nuclear factor-kappaBin developmental and plasticity-associated synaptogenesis
    • Boersma, M. C., Dresselhaus, E. C., De Biase, L. M., Mihalas, A. B., Bergles, D. E., and Meffert, M. K. (2011). A requirement for nuclear factor-kappaBin developmental and plasticity-associated synaptogenesis. J. Neurosci. 31, 5414-5425.
    • (2011) J. Neurosci. , vol.31 , pp. 5414-5425
    • Boersma, M.C.1    Dresselhaus, E.C.2    De Biase, L.M.3    Mihalas, A.B.4    Bergles, D.E.5    Meffert, M.K.6
  • 14
    • 38049117573 scopus 로고    scopus 로고
    • Astroglial nuclear factor-kappaB regulates learning and memory and synaptic plasticity in female mice
    • Bracchi-Ricard, V., Brambilla, R., Lev-enson, J., Hu, W. H., Bramwell, A., Sweatt, J. D., et al. (2008). Astroglial nuclear factor-kappaB regulates learning and memory and synaptic plasticity in female mice. J. Neurochem. 104, 611-623.
    • (2008) J. Neurochem. , vol.104 , pp. 611-623
    • Bracchi-Ricard, V.1    Brambilla, R.2    Lev-enson, J.3    Hu, W.H.4    Bramwell, A.5    Sweatt, J.D.6
  • 15
    • 58149328474 scopus 로고    scopus 로고
    • The immediate early gene arc/arg3.1: regulation, mechanisms, and function
    • Bramham, C. R., Worley, P. F., Moore, M. J., and Guzowski, J. F. (2008). The immediate early gene arc/arg3.1: regulation, mechanisms, and function. J. Neurosci. 28, 11760-11767.
    • (2008) J. Neurosci. , vol.28 , pp. 11760-11767
    • Bramham, C.R.1    Worley, P.F.2    Moore, M.J.3    Guzowski, J.F.4
  • 17
    • 0032571737 scopus 로고    scopus 로고
    • Effect of metabotropic glutamate receptor activation on receptor-mediated cyclic AMP responses in primary cultures of rat striatal neurones
    • Cartmell, J., Goepfert, F., Knoflach, F., Pink, J. R., Bleuel, Z., Richards, J. G., et al. (1998). Effect of metabotropic glutamate receptor activation on receptor-mediated cyclic AMP responses in primary cultures of rat striatal neurones. Brain Res. 791, 191-199.
    • (1998) Brain Res , vol.791 , pp. 191-199
    • Cartmell, J.1    Goepfert, F.2    Knoflach, F.3    Pink, J.R.4    Bleuel, Z.5    Richards, J.G.6
  • 18
    • 0030803961 scopus 로고    scopus 로고
    • mGluR-evoked augmentation of receptor-mediated cyclic AMP formation in neonatal and adult rat striatum
    • Cartmell, J., Schaffhauser, H., Wich-mann, J., and Mutel, V. (1997). mGluR-evoked augmentation of receptor-mediated cyclic AMP formation in neonatal and adult rat striatum. Br. J. Pharmacol. 121, 1263-1268.
    • (1997) Br. J. Pharmacol. , vol.121 , pp. 1263-1268
    • Cartmell, J.1    Schaffhauser, H.2    Wich-mann, J.3    Mutel, V.4
  • 19
    • 0029810979 scopus 로고    scopus 로고
    • Functional coupling between ryanodine receptors and L-type calcium channels in neurons
    • Chavis, P., Fagni, L., Lansman, J. B., and Bockaert, J. (1996). Functional coupling between ryanodine receptors and L-type calcium channels in neurons. Nature 382, 719-722.
    • (1996) Nature , vol.382 , pp. 719-722
    • Chavis, P.1    Fagni, L.2    Lansman, J.B.3    Bockaert, J.4
  • 20
    • 84857238962 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors and the control of chronic pain
    • Chiechio, S., and Nicoletti, F. (2012). Metabotropic glutamate receptors and the control of chronic pain. Curr. Opin. Pharmacol. 12, 28-34.
    • (2012) Curr. Opin. Pharmacol. , vol.12 , pp. 28-34
    • Chiechio, S.1    Nicoletti, F.2
  • 21
    • 0035914172 scopus 로고    scopus 로고
    • Group I metabotropic glutamate receptor activation increases phos-phorylation of cAMP response element-binding protein, Elk-1, and extracellular signal-regulated kinases in rat dorsal striatum
    • Choe, E. S., and Wang, J. Q. (2001). Group I metabotropic glutamate receptor activation increases phos-phorylation of cAMP response element-binding protein, Elk-1, and extracellular signal-regulated kinases in rat dorsal striatum. Brain Res. Mol. Brain Res. 94, 75-84.
    • (2001) Brain Res. Mol. Brain Res. , vol.94 , pp. 75-84
    • Choe, E.S.1    Wang, J.Q.2
  • 22
    • 0037063722 scopus 로고    scopus 로고
    • Regulation of transcription factor phos-phorylation by metabotropic glu-tamate receptor-associated signaling pathways in rat striatal neurons
    • Choe, E. S., and Wang, J. Q. (2002). Regulation of transcription factor phos-phorylation by metabotropic glu-tamate receptor-associated signaling pathways in rat striatal neurons. Neuroscience 114, 557-565.
    • (2002) Neuroscience , vol.114 , pp. 557-565
    • Choe, E.S.1    Wang, J.Q.2
  • 23
    • 38849207033 scopus 로고    scopus 로고
    • Physiological roles of the Ca2+/CaM-dependent protein kinase cascade in health and disease
    • Colomer, J., and Means, A. R. (2007). Physiological roles of the Ca2+/CaM-dependent protein kinase cascade in health and disease. Subcell. Biochem. 45, 169-214.
    • (2007) Subcell. Biochem. , vol.45 , pp. 169-214
    • Colomer, J.1    Means, A.R.2
  • 24
    • 33746046362 scopus 로고    scopus 로고
    • Higher-order organization and regulation of adenylyl cyclases
    • Cooper, D. M., and Crossthwaite, A. J. (2006). Higher-order organization and regulation of adenylyl cyclases. Trends Pharmacol. Sci. 27, 426-431.
    • (2006) Trends Pharmacol. Sci. , vol.27 , pp. 426-431
    • Cooper, D.M.1    Crossthwaite, A.J.2
  • 25
    • 33646252484 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase/extracellular regulated kinase signalling and memory stabilization: a review
    • Davis, S., and Laroche, S. (2006). Mitogen-activated protein kinase/extracellular regulated kinase signalling and memory stabilization: a review. Genes Brain Behav. 5(SUPPL. 2), 61-72.
    • (2006) Genes Brain Behav , vol.5 , Issue.SUPPL. 2 , pp. 61-72
    • Davis, S.1    Laroche, S.2
  • 26
    • 84872125126 scopus 로고    scopus 로고
    • mGlu5R promotes glutamate AMPA receptor phosphorylation via activation of PKA/DARPP-32 signaling in stri-atopallidal medium spiny neurons
    • Apr 7
    • Dell'anno, M. T., Pallottino, S., and Fisone, G. (2012). mGlu5R promotes glutamate AMPA receptor phosphorylation via activation of PKA/DARPP-32 signaling in stri-atopallidal medium spiny neurons. Neuropharmacology. Apr 7.
    • (2012) Neuropharmacology
    • Dell'anno, M.T.1    Pallottino, S.2    Fisone, G.3
  • 27
    • 84855531784 scopus 로고    scopus 로고
    • The role of metabotropic glutamate receptors in addiction: evidence from preclinical models
    • Duncan, J. R., and Lawrence, A. J. (2012). The role of metabotropic glutamate receptors in addiction: evidence from preclinical models. Pharmacol. Biochem. Behav. 100, 811-824.
    • (2012) Pharmacol. Biochem. Behav. , vol.100 , pp. 811-824
    • Duncan, J.R.1    Lawrence, A.J.2
  • 28
    • 63849088930 scopus 로고    scopus 로고
    • Regulation of group I metabotropic glutamate receptor trafficking and signaling by the cave-olar/lipid raft pathway
    • Francesconi, A., Kumari, R., and Zukin, R. S. (2009). Regulation of group I metabotropic glutamate receptor trafficking and signaling by the cave-olar/lipid raft pathway. J. Neurosci. 29, 3590-3602.
    • (2009) J. Neurosci. , vol.29 , pp. 3590-3602
    • Francesconi, A.1    Kumari, R.2    Zukin, R.S.3
  • 30
    • 41249087635 scopus 로고    scopus 로고
    • Transcriptional profiling of the rat frontal cortex following administration of the mGlu5 receptor antagonists MPEP and MTEP
    • Gass, J. T., and Olive, M. F. (2008). Transcriptional profiling of the rat frontal cortex following administration of the mGlu5 receptor antagonists MPEP and MTEP. Eur. J. Pharmacol. 584, 253-262.
    • (2008) Eur. J. Pharmacol. , vol.584 , pp. 253-262
    • Gass, J.T.1    Olive, M.F.2
  • 31
    • 33846901907 scopus 로고    scopus 로고
    • Metabotropic gluta-mate receptors: intracellular signaling pathways
    • Gerber, U., Gee, C. E., and Ben-quet, P. (2007). Metabotropic gluta-mate receptors: intracellular signaling pathways. Curr. Opin. Pharmacol. 7, 56-61.
    • (2007) Curr. Opin. Pharmacol. , vol.7 , pp. 56-61
    • Gerber, U.1    Gee, C.E.2    Ben-quet, P.3
  • 32
    • 73449137227 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor-mediated long-term depression: molecular mechanisms
    • Gladding, C. M., Fitzjohn, S. M., and Molnar, E. (2009). Metabotropic glutamate receptor-mediated long-term depression: molecular mechanisms. Pharmacol. Rev. 61, 395-412.
    • (2009) Pharmacol. Rev. , vol.61 , pp. 395-412
    • Gladding, C.M.1    Fitzjohn, S.M.2    Molnar, E.3
  • 33
    • 77949417517 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors as therapeutic targets for cognitive disorders
    • Gravius, A., Pietraszek, M., Dekundy, A., and Danysz, W. (2010). Metabotropic glutamate receptors as therapeutic targets for cognitive disorders. Curr. Top. Med. Chem. 10, 187-206.
    • (2010) Curr. Top. Med. Chem. , vol.10 , pp. 187-206
    • Gravius, A.1    Pietraszek, M.2    Dekundy, A.3    Danysz, W.4
  • 34
    • 78149495647 scopus 로고    scopus 로고
    • Allosteric modulation of metabotropic glutamate receptors: structural insights and therapeutic potential
    • Gregory, K. J., Dong, E. N., Meiler, J., and Conn, P. J. (2011). Allosteric modulation of metabotropic glutamate receptors: structural insights and therapeutic potential. Neurophar-macology 60, 66-81.
    • (2011) Neurophar-macology , vol.60 , pp. 66-81
    • Gregory, K.J.1    Dong, E.N.2    Meiler, J.3    Conn, P.J.4
  • 35
    • 84856078399 scopus 로고    scopus 로고
    • Therapeutic strategies in fragile X syndrome: dysregulated mGluR signaling and beyond
    • Gross, C., Berry-Kravis, E. M., and Bassell, G. J. (2012). Therapeutic strategies in fragile X syndrome: dysregulated mGluR signaling and beyond. Neuropsychopharmacology 37, 178-195.
    • (2012) Neuropsychopharmacology , vol.37 , pp. 178-195
    • Gross, C.1    Berry-Kravis, E.M.2    Bassell, G.J.3
  • 36
    • 1542616903 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor signalling in perirhinal cortical neurons
    • Harris, S. L., Cho, K., Bashir, Z. I., andMolnar, E.(2004). Metabotropic glutamate receptor signalling in perirhinal cortical neurons. Mol. Cell. Neurosci. 25, 275-287.
    • (2004) Mol. Cell. Neurosci. , vol.25 , pp. 275-287
    • Harris, S.L.1    Cho, K.2    Bashir, Z.I.3    Molnar, E.4
  • 37
    • 33748320817 scopus 로고    scopus 로고
    • RSK and MSK in MAP kinase signalling
    • Hauge, C., and Frodin, M. (2006). RSK and MSK in MAP kinase signalling. J. Cell. Sci. 119, 3021-3023.
    • (2006) J. Cell. Sci. , vol.119 , pp. 3021-3023
    • Hauge, C.1    Frodin, M.2
  • 38
    • 27644487894 scopus 로고    scopus 로고
    • Signal transduction pathways of group I metabotropic glutamate receptor-induced long-term depression at sensory spinal synapses
    • Heinke, B., and Sandkuhler, J. (2005). Signal transduction pathways of group I metabotropic glutamate receptor-induced long-term depression at sensory spinal synapses. Pain 118, 145-154.
    • (2005) Pain , vol.118 , pp. 145-154
    • Heinke, B.1    Sandkuhler, J.2
  • 39
    • 0034279245 scopus 로고    scopus 로고
    • Impaired synaptic plasticity and cAMP response element-binding protein activation in Ca2+/calmodulin-dependent protein kinase type IV/Gr-deficient mice
    • Ho, N., Liauw, J. A., Blaeser, F., Wei, F., Hanissian, S., Muglia, L. M., et al. (2000). Impaired synaptic plasticity and cAMP response element-binding protein activation in Ca2+/calmodulin-dependent protein kinase type IV/Gr-deficient mice. J. Neurosci. 20, 6459-6472.
    • (2000) J. Neurosci. , vol.20 , pp. 6459-6472
    • Ho, N.1    Liauw, J.A.2    Blaeser, F.3    Wei, F.4    Hanissian, S.5    Muglia, L.M.6
  • 40
    • 0035028435 scopus 로고    scopus 로고
    • Ca(2+)/CaM-dependent kinases: from activation to function
    • Hook, S. S., and Means, A. R. (2001). Ca(2+)/CaM-dependent kinases: from activation to function. Annu. Rev. Pharmacol. Toxicol. 41, 471-505.
    • (2001) Annu. Rev. Pharmacol. Toxicol. , vol.41 , pp. 471-505
    • Hook, S.S.1    Means, A.R.2
  • 41
    • 33746866693 scopus 로고    scopus 로고
    • Dynamic translational and proteasomal regulation of fragile X mental retardation protein controls mGluR-dependent long-term depression
    • Hou, L., Antion, M. D., Hu, D., Spencer, C. M., Paylor, R., and Klann, E. (2006). Dynamic translational and proteasomal regulation of fragile X mental retardation protein controls mGluR-dependent long-term depression. Neuron 51, 441-454.
    • (2006) Neuron , vol.51 , pp. 441-454
    • Hou, L.1    Antion, M.D.2    Hu, D.3    Spencer, C.M.4    Paylor, R.5    Klann, E.6
  • 42
    • 1842530221 scopus 로고    scopus 로고
    • Rap1-induced p38 mitogen-activated protein kinase activation facilitates AMPA receptor trafficking via the GDI.Rab5 complex. Potential role in (S)-3, 5-dihydroxyphenylglycene-induced long term depression
    • Huang, C. C., You, J. L., Wu, M. Y., and Hsu, K. S. (2004). Rap1-induced p38 mitogen-activated protein kinase activation facilitates AMPA receptor trafficking via the GDI.Rab5 complex. Potential role in (S)-3, 5-dihydroxyphenylglycene-induced long term depression. J. Biol. Chem. 279, 12286-12292.
    • (2004) J. Biol. Chem. , vol.279 , pp. 12286-12292
    • Huang, C.C.1    You, J.L.2    Wu, M.Y.3    Hsu, K.S.4
  • 43
    • 0034685813 scopus 로고    scopus 로고
    • Role for rapid dendritic protein synthesis in hippocam-pal mGluR-dependent long-term depression
    • Huber, K. M., Kayser, M. S., and Bear, M. F. (2000). Role for rapid dendritic protein synthesis in hippocam-pal mGluR-dependent long-term depression. Science 288, 1254-1257.
    • (2000) Science , vol.288 , pp. 1254-1257
    • Huber, K.M.1    Kayser, M.S.2    Bear, M.F.3
  • 44
    • 0036460129 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors mediate expression of LTP in slices of rat visual cortex
    • Huemmeke, M., Eysel, U. T., and Mittmann, T. (2002). Metabotropic glutamate receptors mediate expression of LTP in slices of rat visual cortex. Eur. J. Neurosci. 15, 1641-1645.
    • (2002) Eur. J. Neurosci. , vol.15 , pp. 1641-1645
    • Huemmeke, M.1    Eysel, U.T.2    Mittmann, T.3
  • 45
    • 0035874373 scopus 로고    scopus 로고
    • CREB signaling - timing is everything
    • pe1
    • Impey, S., and Goodman, R. H. (2001). CREB signaling - timing is everything. Sci. STKE 2001, pe1.
    • (2001) Sci. STKE
    • Impey, S.1    Goodman, R.H.2
  • 46
    • 72149133087 scopus 로고    scopus 로고
    • Intracellular metabotropic glutamate receptor 5 (mGluR5) activates signaling cascades distinct from cell surface counterparts
    • Jong, Y. J., Kumar, V., and O'Malley, K. L. (2009). Intracellular metabotropic glutamate receptor 5 (mGluR5) activates signaling cascades distinct from cell surface counterparts. J. Biol. Chem. 284, 35827-35838.
    • (2009) J. Biol. Chem. , vol.284 , pp. 35827-35838
    • Jong, Y.J.1    Kumar, V.2    O'Malley, K.L.3
  • 47
    • 26844540411 scopus 로고    scopus 로고
    • CREB, synapses and memory disorders: past progress and future challenges
    • Josselyn, S. A., and Nguyen, P. V. (2005). CREB, synapses and memory disorders: past progress and future challenges. Curr. Drug Targets CNS Neu-rol. Disord. 4, 481-497.
    • (2005) Curr. Drug Targets CNS Neu-rol. Disord. , vol.4 , pp. 481-497
    • Josselyn, S.A.1    Nguyen, P.V.2
  • 48
    • 84860806555 scopus 로고    scopus 로고
    • The molecular biology of memory: cAMP, PKA, CRE, CREB-1, CREB-2, and CPEB
    • Kandel, E. R. (2012). The molecular biology of memory: cAMP, PKA, CRE, CREB-1, CREB-2, and CPEB. Mol Brain 5, 14.
    • (2012) Mol Brain , vol.5 , pp. 14
    • Kandel, E.R.1
  • 49
    • 38049084115 scopus 로고    scopus 로고
    • Metabotropic glu-tamate receptors: phosphorylation and receptor signaling
    • Kim, C. H., Lee, J., Lee, J. Y., and Roche, K. W. (2008). Metabotropic glu-tamate receptors: phosphorylation and receptor signaling. J. Neurosci. Res. 86, 1-10.
    • (2008) J. Neurosci. Res. , vol.86 , pp. 1-10
    • Kim, C.H.1    Lee, J.2    Lee, J.Y.3    Roche, K.W.4
  • 50
    • 82455205755 scopus 로고    scopus 로고
    • Arc in synaptic plasticity: from gene to behavior
    • Korb, E., and Finkbeiner, S. (2011). Arc in synaptic plasticity: from gene to behavior. Trends Neurosci. 34, 591-598.
    • (2011) Trends Neurosci , vol.34 , pp. 591-598
    • Korb, E.1    Finkbeiner, S.2
  • 51
    • 0037061719 scopus 로고    scopus 로고
    • CREB transcriptional activity in neurons is regulated by multiple, calcium-specific phosphoryla-tion events
    • Kornhauser, J. M., Cowan, C. W., Shaywitz, A. J., Dolmetsch, R. E., Griffith, E. C., Hu, L. S., et al. (2002). CREB transcriptional activity in neurons is regulated by multiple, calcium-specific phosphoryla-tion events. Neuron 34, 221-233.
    • (2002) Neuron , vol.34 , pp. 221-233
    • Kornhauser, J.M.1    Cowan, C.W.2    Shaywitz, A.J.3    Dolmetsch, R.E.4    Griffith, E.C.5    Hu, L.S.6
  • 52
    • 79952301339 scopus 로고    scopus 로고
    • Cognitive dysfunction and prefrontal synaptic abnormalities in a mouse model of fragile X syndrome
    • Krueger, D. D., Osterweil, E. K., Chen, S. P., Tye, L. D., and Bear, M. F. (2011). Cognitive dysfunction and prefrontal synaptic abnormalities in a mouse model of fragile X syndrome. Proc. Natl. Acad. Sci. U.S.A. 108, 2587-2592.
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 2587-2592
    • Krueger, D.D.1    Osterweil, E.K.2    Chen, S.P.3    Tye, L.D.4    Bear, M.F.5
  • 53
    • 34548037876 scopus 로고    scopus 로고
    • Long-term synaptic plasticity in hippocampal interneurons
    • Kullmann, D. M., and Lamsa, K. P. (2007). Long-term synaptic plasticity in hippocampal interneurons. Nat. Rev. Neurosci. 8, 687-699.
    • (2007) Nat. Rev. Neurosci. , vol.8 , pp. 687-699
    • Kullmann, D.M.1    Lamsa, K.P.2
  • 54
    • 84857348229 scopus 로고    scopus 로고
    • Activation of intracellu-lar metabotropic glutamate receptor 5 in striatal neurons leads to up-regulation of genes associated with sustained synaptic transmission including Arc/Arg3, 1 protein
    • Kumar, V., Fahey, P. G., Jong, Y. J., Ramanan, N., and O'Malley, K. L. (2012). Activation of intracellu-lar metabotropic glutamate receptor 5 in striatal neurons leads to up-regulation of genes associated with sustained synaptic transmission including Arc/Arg3.1 protein. J. Biol. Chem. 287, 5412-5425.
    • (2012) J. Biol. Chem. , vol.287 , pp. 5412-5425
    • Kumar, V.1    Fahey, P.G.2    Jong, Y.J.3    Ramanan, N.4    O'Malley, K.L.5
  • 55
    • 78751528230 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species are activated by mGluR5 through IP3 and activate ERK and PKA to increase excitability of amygdala neurons and pain behavior
    • Li, Z., Ji, G., and Neugebauer, V. (2011). Mitochondrial reactive oxygen species are activated by mGluR5 through IP3 and activate ERK and PKA to increase excitability of amygdala neurons and pain behavior. J. Neurosci. 31, 1114-1127.
    • (2011) J. Neurosci. , vol.31 , pp. 1114-1127
    • Li, Z.1    Ji, G.2    Neugebauer, V.3
  • 56
    • 21544438755 scopus 로고    scopus 로고
    • Calcium-stimulated adeny-lyl cyclases required for long-term potentiation in the anterior cin-gulate cortex
    • Liauw, J., Wu, L. J., and Zhuo, M. (2005). Calcium-stimulated adeny-lyl cyclases required for long-term potentiation in the anterior cin-gulate cortex. J. Neurophysiol. 94, 878-882.
    • (2005) J. Neurophysiol. , vol.94 , pp. 878-882
    • Liauw, J.1    Wu, L.J.2    Zhuo, M.3
  • 57
    • 0346668358 scopus 로고    scopus 로고
    • Mechanism of regulation of casein kinase I activity by group I metabotropic gluta-mate receptors
    • Liu, F., Virshup, D. M., Nairn, A. C., and Greengard, P. (2002). Mechanism of regulation of casein kinase I activity by group I metabotropic gluta-mate receptors. J. Biol. Chem. 277, 45393-45399.
    • (2002) J. Biol. Chem. , vol.277 , pp. 45393-45399
    • Liu, F.1    Virshup, D.M.2    Nairn, A.C.3    Greengard, P.4
  • 58
    • 0037101970 scopus 로고    scopus 로고
    • Function and regulation of CREB family transcription factors in the nervous system
    • Lonze, B. E., and Ginty, D. D. (2002). Function and regulation of CREB family transcription factors in the nervous system. Neuron 35, 605-623.
    • (2002) Neuron , vol.35 , pp. 605-623
    • Lonze, B.E.1    Ginty, D.D.2
  • 59
    • 0038587594 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 5-regulated Elk-1 phosphorylation andimmediate earlygeneexpression in striatal neurons
    • Mao, L., and Wang, J. Q. (2003a). Metabotropic glutamate receptor 5-regulated Elk-1 phosphorylation andimmediate earlygeneexpression in striatal neurons. J. Neurochem. 85, 1006-1017.
    • (2003) J. Neurochem. , vol.85 , pp. 1006-1017
    • Mao, L.1    Wang, J.Q.2
  • 60
    • 0037295133 scopus 로고    scopus 로고
    • Group I metabotropic glutamate receptor-mediated calcium signalling and immediate early gene expression in cultured rat striatal neurons
    • Mao, L., andWang, J.Q. (2003b). Group I metabotropic glutamate receptor-mediated calcium signalling and immediate early gene expression in cultured rat striatal neurons. Eur. J. Neurosci. 17, 741-750.
    • (2003) Eur. J. Neurosci , vol.17 , pp. 741-750
    • Mao, L.1    Wang, J.Q.2
  • 61
    • 0037269640 scopus 로고    scopus 로고
    • Phosphorylation of cAMP response element-binding protein in cultured striatal neurons by metabotropic glutamate receptor subtype 5
    • Mao, L., and Wang, J. Q. (2003c). Phosphorylation of cAMP response element-binding protein in cultured striatal neurons by metabotropic glutamate receptor subtype 5. J. Neurochem. 84, 233-243.
    • (2003) J. Neurochem. , vol.84 , pp. 233-243
    • Mao, L.1    Wang, J.Q.2
  • 62
    • 14944372499 scopus 로고    scopus 로고
    • The scaffold protein Homer1b/c links metabotropic glutamate receptor 5toextracellular signal-regulated protein kinase cascades in neurons
    • Mao, L., Yang, L., Tang, Q., Samdani, S., Zhang, G., and Wang, J. Q. (2005). The scaffold protein Homer1b/c links metabotropic glutamate receptor 5toextracellular signal-regulated protein kinase cascades in neurons. J. Neurosci. 25, 2741-2752.
    • (2005) J. Neurosci. , vol.25 , pp. 2741-2752
    • Mao, L.1    Yang, L.2    Tang, Q.3    Samdani, S.4    Zhang, G.5    Wang, J.Q.6
  • 63
    • 51749112647 scopus 로고    scopus 로고
    • Group I metabotropic glutamate receptor-mediated gene expression in striatal neurons
    • Mao, L. M., Zhang, G. C., Liu, X. Y., Fibuch, E. E., and Wang, J. Q. (2008). Group I metabotropic glutamate receptor-mediated gene expression in striatal neurons. Neurochem. Res. 33, 1920-1924.
    • (2008) Neurochem. Res , vol.33 , pp. 1920-1924
    • Mao, L.M.1    Zhang, G.C.2    Liu, X.Y.3    Fibuch, E.E.4    Wang, J.Q.5
  • 64
    • 33749055328 scopus 로고    scopus 로고
    • NF-kappaB functions inthenervous system:from development to disease
    • Memet, S. (2006). NF-kappaB functions inthenervous system:from development to disease. Biochem. Pharmacol. 72, 1180-1195.
    • (2006) Biochem. Pharmacol. , vol.72 , pp. 1180-1195
    • Memet, S.1
  • 65
    • 79956327026 scopus 로고    scopus 로고
    • Calcium/calmodulin-dependent protein kinase II mediates group I metabotropic glutamate receptor-dependent protein synthesis and long-term depression in rat hippocampus
    • Mockett, B. G., Guevremont, D., Wutte, M., Hulme, S. R., Williams, J. M., and Abraham, W. C. (2011). Calcium/calmodulin-dependent protein kinase II mediates group I metabotropic glutamate receptor-dependent protein synthesis and long-term depression in rat hippocampus. J. Neurosci. 31, 7380-7391.
    • (2011) J. Neurosci. , vol.31 , pp. 7380-7391
    • Mockett, B.G.1    Guevremont, D.2    Wutte, M.3    Hulme, S.R.4    Williams, J.M.5    Abraham, W.C.6
  • 66
    • 0041346211 scopus 로고    scopus 로고
    • Rap1 couples cAMP signaling to a distinct pool of p42/44MAPK regulating excitability, synaptic plasticity, learning, and memory
    • Morozov, A., Muzzio, I. A., Bourtchouladze, R., Van-Strien, N., Lapidus, K., Yin, D., et al. (2003). Rap1 couples cAMP signaling to a distinct pool of p42/44MAPK regulating excitability, synaptic plasticity, learning, and memory. Neuron 39, 309-325.
    • (2003) Neuron , vol.39 , pp. 309-325
    • Morozov, A.1    Muzzio, I.A.2    Bourtchouladze, R.3    Van-Strien, N.4    Lapidus, K.5    Yin, D.6
  • 68
    • 77949516412 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors: physiology, pharmacology, and disease
    • Niswender, C. M., and Conn, P. J. (2010). Metabotropic glutamate receptors: physiology, pharmacology, and disease. Annu. Rev. Pharmacol. Toxicol. 50, 295-322.
    • (2010) Annu. Rev. Pharmacol. Toxicol. , vol.50 , pp. 295-322
    • Niswender, C.M.1    Conn, P.J.2
  • 69
    • 33646194363 scopus 로고    scopus 로고
    • Metabotropic receptor-dependent long-term depression persists in the absence of protein synthesis in the mouse model of fragile X syndrome
    • Nosyreva, E. D., and Huber, K. M. (2006). Metabotropic receptor-dependent long-term depression persists in the absence of protein synthesis in the mouse model of fragile X syndrome. J. Neurophysiol. 95, 3291-3295.
    • (2006) J. Neurophysiol. , vol.95 , pp. 3291-3295
    • Nosyreva, E.D.1    Huber, K.M.2
  • 70
    • 84860871082 scopus 로고    scopus 로고
    • Inverse synaptic tagging of inactive synapses via dynamic interaction of Arc/Arg3, 1 with CaMKIIbeta
    • Okuno, H., Akashi, K., Ishii, Y., Yagishita-Kyo, N., Suzuki, K., Nonaka, M., et al. (2012). Inverse synaptic tagging of inactive synapses via dynamic interaction of Arc/Arg3.1 with CaMKIIbeta. Cell 149, 886-898.
    • (2012) Cell , vol.149 , pp. 886-898
    • Okuno, H.1    Akashi, K.2    Ishii, Y.3    Yagishita-Kyo, N.4    Suzuki, K.5    Nonaka, M.6
  • 71
    • 33749181999 scopus 로고    scopus 로고
    • NF-kappaB/Rel regulates inhibitory and excitatory neuronal function and synap-tic plasticity
    • O'Mahony, A., Raber, J., Montano, M., Foehr, E., Han, V., Lu, S. M., et al. (2006). NF-kappaB/Rel regulates inhibitory and excitatory neuronal function and synap-tic plasticity. Mol. Cell. Biol. 26, 7283-7298.
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 7283-7298
    • O'Mahony, A.1    Raber, J.2    Montano, M.3    Foehr, E.4    Han, V.5    Lu, S.M.6
  • 72
    • 33646939550 scopus 로고    scopus 로고
    • Regulation of nuclear factor kappaB in the hippocampus by group I metabotropic glu-tamate receptors
    • O'Riordan, K. J., Huang, I. C., Pizzi, M., Spano, P., Boroni, F., Egli, R., et al. (2006). Regulation of nuclear factor kappaB in the hippocampus by group I metabotropic glu-tamate receptors. J. Neurosci. 26, 4870-4879.
    • (2006) J. Neurosci. , vol.26 , pp. 4870-4879
    • O'Riordan, K.J.1    Huang, I.C.2    Pizzi, M.3    Spano, P.4    Boroni, F.5    Egli, R.6
  • 73
    • 46149087988 scopus 로고    scopus 로고
    • Elongation factor 2 and fragile X mental retardation protein control the dynamic translation of Arc/Arg3, 1 essential for mGluR-LTD
    • Park, S., Park, J. M., Kim, S., Kim, J. A., Shepherd, J. D., Smith-Hicks, C. L., et al. (2008). Elongation factor 2 and fragile X mental retardation protein control the dynamic translation of Arc/Arg3.1 essential for mGluR-LTD. Neuron 59, 70-83.
    • (2008) Neuron , vol.59 , pp. 70-83
    • Park, S.1    Park, J.M.2    Kim, S.3    Kim, J.A.4    Shepherd, J.D.5    Smith-Hicks, C.L.6
  • 75
    • 21744444009 scopus 로고    scopus 로고
    • NF-kappaB factor c-Rel mediates neuropro-tection elicited by mGlu5 receptor agonists against amyloid beta-peptide toxicity
    • Pizzi, M., Sarnico, I., Boroni, F., Benarese, M., Steimberg, N., Maz-zoleni, G., et al. (2005). NF-kappaB factor c-Rel mediates neuropro-tection elicited by mGlu5 receptor agonists against amyloid beta-peptide toxicity.Cell DeathDiffer.12, 761-772.
    • (2005) Cell DeathDiffer , vol.12 , pp. 761-772
    • Pizzi, M.1    Sarnico, I.2    Boroni, F.3    Benarese, M.4    Steimberg, N.5    Maz-zoleni, G.6
  • 76
    • 65649094399 scopus 로고    scopus 로고
    • Persistent transcription- and translation-dependent long-term potentiation induced by mGluR1 in hippocam-pal interneurons
    • Ran, I., Laplante, I., Bourgeois, C., Pepin, J., Lacaille, P., Costa-Mattioli, M., et al. (2009). Persistent transcription- and translation-dependent long-term potentiation induced by mGluR1 in hippocam-pal interneurons. J. Neurosci. 29, 5605-5615.
    • (2009) J. Neurosci. , vol.29 , pp. 5605-5615
    • Ran, I.1    Laplante, I.2    Bourgeois, C.3    Pepin, J.4    Lacaille, P.5    Costa-Mattioli, M.6
  • 77
    • 84860342691 scopus 로고    scopus 로고
    • CREB-dependent transcrip-tional control and quantal changes in persistent long-term potentia-tion in hippocampal interneurons
    • Ran, I., Laplante, I., and Lacaille, J. C. (2012). CREB-dependent transcrip-tional control and quantal changes in persistent long-term potentia-tion in hippocampal interneurons. J. Neurosci. 32, 6335-6350.
    • (2012) J. Neurosci. , vol.32 , pp. 6335-6350
    • Ran, I.1    Laplante, I.2    Lacaille, J.C.3
  • 78
    • 78649281822 scopus 로고    scopus 로고
    • Group I metabotropic glutamate receptor signalling and its implication in neurological disease
    • Ribeiro, F. M., Paquet, M., Cregan, S. P., and Ferguson, S. S. (2010). Group I metabotropic glutamate receptor signalling and its implication in neurological disease. CNS Neurol. Dis-ord. Drug Targets 9, 574-595.
    • (2010) CNS Neurol. Dis-ord. Drug Targets , vol.9 , pp. 574-595
    • Ribeiro, F.M.1    Paquet, M.2    Cregan, S.P.3    Ferguson, S.S.4
  • 79
    • 79951552862 scopus 로고    scopus 로고
    • Huntington's disease and group Imetabotropic glutamate receptors
    • Ribeiro, F.M., Pires, R. G., and Ferguson, S. S. (2011). Huntington's disease and group Imetabotropic glutamate receptors. Mol. Neurobiol. 43, 1-11.
    • (2011) Mol. Neurobiol. , vol.43 , pp. 1-11
    • Ribeiro, F.M.1    Pires, R.G.2    Ferguson, S.S.3
  • 80
    • 33748906250 scopus 로고    scopus 로고
    • Evolutionarily-conserved role of the NF-kappaB transcription factor in neural plasticity and memory
    • Romano, A., Freudenthal, R., Merlo, E., and Routtenberg, A. (2006). Evolutionarily-conserved role of the NF-kappaB transcription factor in neural plasticity and memory. Eur. J. Neurosci. 24, 1507-1516.
    • (2006) Eur. J. Neurosci. , vol.24 , pp. 1507-1516
    • Romano, A.1    Freudenthal, R.2    Merlo, E.3    Routtenberg, A.4
  • 81
    • 80955145685 scopus 로고    scopus 로고
    • Advances in understanding fragile X syndrome and related disorders
    • Rooms, L., and Kooy, R. F. (2011). Advances in understanding fragile X syndrome and related disorders. Curr. Opin. Pediatr. 23, 601-606.
    • (2011) Curr. Opin. Pediatr. , vol.23 , pp. 601-606
    • Rooms, L.1    Kooy, R.F.2
  • 82
    • 0030826916 scopus 로고    scopus 로고
    • Involvement of a cyclic-AMP pathway in group I metabotropic glutamate receptor responses in neonatal rat cortex
    • Schaffhauser, H., de Barry, J., Muller, H., Heitz, M. P., Gombos, G., and Mutel, V. (1997). Involvement of a cyclic-AMP pathway in group I metabotropic glutamate receptor responses in neonatal rat cortex. Eur. J. Pharmacol. 334, 289-297.
    • (1997) Eur. J. Pharmacol. , vol.334 , pp. 289-297
    • Schaffhauser, H.1    de Barry, J.2    Muller, H.3    Heitz, M.P.4    Gombos, G.5    Mutel, V.6
  • 83
    • 70349909566 scopus 로고    scopus 로고
    • Fragile X mental retardation protein is required for chemically-induced long-term potentiation of the hippocampus in adult mice
    • Shang, Y., Wang, H., Mercaldo, V., Li, X., Chen, T., and Zhuo, M. (2009). Fragile X mental retardation protein is required for chemically-induced long-term potentiation of the hippocampus in adult mice. J. Neu-rochem. 111, 635-646.
    • (2009) J. Neu-rochem , vol.111 , pp. 635-646
    • Shang, Y.1    Wang, H.2    Mercaldo, V.3    Li, X.4    Chen, T.5    Zhuo, M.6
  • 84
    • 79952006979 scopus 로고    scopus 로고
    • New views of Arc, a master regulator of synaptic plasticity
    • Shepherd, J. D., and Bear, M. F. (2011). New views of Arc, a master regulator of synaptic plasticity. Nat. Neurosci. 14, 279-284.
    • (2011) Nat. Neurosci. , vol.14 , pp. 279-284
    • Shepherd, J.D.1    Bear, M.F.2
  • 85
    • 34548342930 scopus 로고    scopus 로고
    • NF-kappaB activity in distinct neural subtypes of the rat hippocampus: influence of time and GABA antagonism in acute slice preparations
    • Sheridan, G. K., Pickering, M., Twomey, C., Moynagh, P. N., O'Connor, J. J., and Murphy, K. J. (2007). NF-kappaB activity in distinct neural subtypes of the rat hippocampus: influence of time and GABA antagonism in acute slice preparations. Learn. Mem. 14, 525-532.
    • (2007) Learn. Mem. , vol.14 , pp. 525-532
    • Sheridan, G.K.1    Pickering, M.2    Twomey, C.3    Moynagh, P.N.4    O'Connor, J.J.5    Murphy, K.J.6
  • 86
    • 49449107546 scopus 로고    scopus 로고
    • Essential role for epidermal growth factor receptor in glutamate receptor signaling to NF-kappaB
    • Sitcheran, R., Comb, W. C., Cogswell, P. C., and Baldwin, A. S. (2008). Essential role for epidermal growth factor receptor in glutamate receptor signaling to NF-kappaB. Mol. Cell. Biol. 28, 5061-5070.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 5061-5070
    • Sitcheran, R.1    Comb, W.C.2    Cogswell, P.C.3    Baldwin, A.S.4
  • 88
    • 0141541343 scopus 로고    scopus 로고
    • Isoforms of mammalian adenylyl cyclase: multiplicities of signaling
    • Sunahara, R. K., and Taussig, R. (2002). Isoforms of mammalian adenylyl cyclase: multiplicities of signaling. Mol. Interv. 2, 168-184.
    • (2002) Mol. Interv. , vol.2 , pp. 168-184
    • Sunahara, R.K.1    Taussig, R.2
  • 89
    • 79959306968 scopus 로고    scopus 로고
    • Upregula-tion of CREB-mediated transcription enhances both short- and long-term memory
    • Suzuki, A., Fukushima, H., Mukawa, T., Toyoda, H., Wu, L. J., Zhao, M. G., et al. (2011). Upregula-tion of CREB-mediated transcription enhances both short- and long-term memory. J. Neurosci. 31, 8786-8802.
    • (2011) J. Neurosci. , vol.31 , pp. 8786-8802
    • Suzuki, A.1    Fukushima, H.2    Mukawa, T.3    Toyoda, H.4    Wu, L.J.5    Zhao, M.G.6
  • 90
    • 77951883483 scopus 로고    scopus 로고
    • Microfluidic local perfusion chambers for the visualization and manipulation of synapses
    • Taylor, A. M., Dieterich, D. C., Ito, H. T., Kim, S. A., and Schuman, E. M. (2010). Microfluidic local perfusion chambers for the visualization and manipulation of synapses. Neuron 66, 57-68.
    • (2010) Neuron , vol.66 , pp. 57-68
    • Taylor, A.M.1    Dieterich, D.C.2    Ito, H.T.3    Kim, S.A.4    Schuman, E.M.5
  • 91
    • 67650550794 scopus 로고    scopus 로고
    • Ca2+/calmodulin-dependent protein kinase IV links group I metabotropic glutamate receptors to fragile X mental retardation protein in cingulate cortex
    • Wang, H., Fukushima, H., Kida, S., and Zhuo, M. (2009a). Ca2+/calmodulin-dependent protein kinase IV links group I metabotropic glutamate receptors to fragile X mental retardation protein in cingulate cortex. J. Biol. Chem. 284, 18953-18962.
    • (2009) J. Biol. Chem. , vol.284 , pp. 18953-18962
    • Wang, H.1    Fukushima, H.2    Kida, S.3    Zhuo, M.4
  • 92
    • 67349157826 scopus 로고    scopus 로고
    • Converging signal on ERK1/2 activity regulates group I mGluR-mediated Arc transcription
    • Wang, Y., Zheng, F., Zhou, X., Sun, Z., and Wang, H. (2009b). Converging signal on ERK1/2 activity regulates group I mGluR-mediated Arc transcription. Neurosci. Lett. 460, 36-40.
    • (2009) Neurosci. Lett. , vol.460 , pp. 36-40
    • Wang, Y.1    Zheng, F.2    Zhou, X.3    Sun, Z.4    Wang, H.5
  • 93
    • 33847711874 scopus 로고    scopus 로고
    • Genetic evidence for adenylyl cyclase 1 as a target for preventing neuronal excito-toxicity mediated by N-methyl-d-aspartate receptors
    • Wang, H., Gong, B., Vadakkan, K. I., Toyoda, H., Kaang, B. K., and Zhuo, M. (2007a). Genetic evidence for adenylyl cyclase 1 as a target for preventing neuronal excito-toxicity mediated by N-methyl-d-aspartate receptors. J. Biol. Chem. 282, 1507-1517.
    • (2007) J. Biol. Chem. , vol.282 , pp. 1507-1517
    • Wang, H.1    Gong, B.2    Vadakkan, K.I.3    Toyoda, H.4    Kaang, B.K.5    Zhuo, M.6
  • 94
    • 33846245536 scopus 로고    scopus 로고
    • Regulation of mitogen-activated protein kinases by gluta-mate receptors
    • Wang, J. Q., Fibuch, E. E., and Mao, L. (2007b). Regulation of mitogen-activated protein kinases by gluta-mate receptors. J. Neurochem. 100, 1-11.
    • (2007) J. Neurochem. , vol.100 , pp. 1-11
    • Wang, J.Q.1    Fibuch, E.E.2    Mao, L.3
  • 95
    • 77954368724 scopus 로고    scopus 로고
    • Roles of fragile X mental retardation protein in dopaminergic stimulation-induced synapse-associated protein synthesis and subsequent alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-4-propionate (AMPA) receptor internalization
    • Wang, H., Kim, S. S., and Zhuo, M. (2010). Roles of fragile X mental retardation protein in dopaminergic stimulation-induced synapse-associated protein synthesis and subsequent alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-4-propionate (AMPA) receptor internalization. J. Biol. Chem. 285, 21888-21901.
    • (2010) J. Biol. Chem. , vol.285 , pp. 21888-21901
    • Wang, H.1    Kim, S.S.2    Zhuo, M.3
  • 96
    • 84864506400 scopus 로고    scopus 로고
    • Roles of CREB in the regulation of FMRP by group I metabotropic glutamate receptors in cingulate cortex
    • Wang, H., Morishita, Y., Miura, D., Naranjo, J. R., Kida, S., and Zhuo, M. (2012a). Roles of CREB in the regulation of FMRP by group I metabotropic glutamate receptors in cingulate cortex. Mol Brain 5, 27.
    • (2012) Mol Brain , vol.5 , pp. 27
    • Wang, H.1    Morishita, Y.2    Miura, D.3    Naranjo, J.R.4    Kida, S.5    Zhuo, M.6
  • 97
    • 84862803170 scopus 로고    scopus 로고
    • New perspectives on the biology of fragile X syndrome
    • Wang, T., Bray, S. M., and Warren, S. T. (2012b). New perspectives on the biology of fragile X syndrome. Curr. Opin. Genet. Dev. 22, 256-263.
    • (2012) Curr. Opin. Genet. Dev. , vol.22 , pp. 256-263
    • Wang, T.1    Bray, S.M.2    Warren, S.T.3
  • 98
    • 0037334533 scopus 로고    scopus 로고
    • Calmodulin-regulated adenylyl cyclases: cross-talk and plasticity in the central nervous system
    • Wang, H., and Storm, D. R. (2003). Calmodulin-regulated adenylyl cyclases: cross-talk and plasticity in the central nervous system. Mol. Pharmacol. 63, 463-468.
    • (2003) Mol. Pharmacol. , vol.63 , pp. 463-468
    • Wang, H.1    Storm, D.R.2
  • 99
    • 43749093221 scopus 로고    scopus 로고
    • Roles of calcium-stimulated adenylyl cyclase and calmodulin-dependent protein kinase IV in the regulation of FMRP by group I metabotropic glutamate receptors
    • Wang, H., Wu, L. J., Zhang, F., and Zhuo, M. (2008a). Roles of calcium-stimulated adenylyl cyclase and calmodulin-dependent protein kinase IV in the regulation of FMRP by group I metabotropic glutamate receptors. J. Neurosci.28, 4385-4397.
    • (2008) J. Neurosci. , vol.28 , pp. 4385-4397
    • Wang, H.1    Wu, L.J.2    Zhang, F.3    Zhuo, M.4
  • 100
    • 49849098290 scopus 로고    scopus 로고
    • FMRP acts as a key messenger for dopamine modulation in the forebrain
    • Wang, H., Wu, L. J., Kim, S. S., Lee, F. J., Gong, B., Toyoda, H., et al. (2008b). FMRP acts as a key messenger for dopamine modulation in the forebrain. Neuron 59, 634-647.
    • (2008) Neuron , vol.59 , pp. 634-647
    • Wang, H.1    Wu, L.J.2    Kim, S.S.3    Lee, F.J.4    Gong, B.5    Toyoda, H.6
  • 101
    • 78651410141 scopus 로고    scopus 로고
    • Identification of an adenylyl cyclase inhibitor for treating neuropathic and inflammatory pain
    • 65ra63
    • Wang, H., Xu, H., Wu, L. J., Kim, S. S., Chen, T., Koga, K., et al. (2011). Identification of an adenylyl cyclase inhibitor for treating neuropathic and inflammatory pain. Sci. Transl. Med. 3, 65ra63.
    • (2011) Sci. Transl. Med. , vol.3
    • Wang, H.1    Xu, H.2    Wu, L.J.3    Kim, S.S.4    Chen, T.5    Koga, K.6
  • 102
    • 68649093278 scopus 로고    scopus 로고
    • Protein translation in synaptic plasticity: mGluR-LTD, fragile X
    • Waung, M.W., and Huber, K.M.(2009). Protein translation in synaptic plasticity: mGluR-LTD, fragile X. Curr. Opin. Neurobiol. 19, 319-326.
    • (2009) Curr. Opin. Neurobiol. , vol.19 , pp. 319-326
    • Waung, M.W.1    Huber, K.M.2
  • 103
    • 46149123205 scopus 로고    scopus 로고
    • Rapid translation of Arc/Arg3, 1 selectively mediates mGluR-dependent LTD through persistent increases in AMPAR endocytosis rate
    • Waung, M. W., Pfeiffer, B. E., Nosyreva, E. D., Ronesi, J. A., and Huber, K. M. (2008). Rapid translation of Arc/Arg3.1 selectively mediates mGluR-dependent LTD through persistent increases in AMPAR endocytosis rate. Neuron 59, 84-97.
    • (2008) Neuron , vol.59 , pp. 84-97
    • Waung, M.W.1    Pfeiffer, B.E.2    Nosyreva, E.D.3    Ronesi, J.A.4    Huber, K.M.5
  • 104
    • 52049121528 scopus 로고    scopus 로고
    • Calmodulin-kinases: modulators of neuronal development and plasticity
    • Wayman, G. A., Lee, Y. S., Tokumitsu, H., Silva, A. J., and Soderling, T. R. (2008). Calmodulin-kinases: modulators of neuronal development and plasticity. Neuron 59, 914-931.
    • (2008) Neuron , vol.59 , pp. 914-931
    • Wayman, G.A.1    Lee, Y.S.2    Tokumitsu, H.3    Silva, A.J.4    Soderling, T.R.5
  • 106
    • 0036270962 scopus 로고    scopus 로고
    • Calcium calmodulin-dependent protein kinase IV is required for fear memory
    • Wei, F., Qiu, C. S., Liauw, J., Robinson, D. A., Ho, N., Chatila, T., et al. (2002a). Calcium calmodulin-dependent protein kinase IV is required for fear memory. Nat. Neu-rosci. 5, 573-579.
    • (2002) Nat. Neu-rosci. , vol.5 , pp. 573-579
    • Wei, F.1    Qiu, C.S.2    Liauw, J.3    Robinson, D.A.4    Ho, N.5    Chatila, T.6
  • 107
    • 18744396642 scopus 로고    scopus 로고
    • Genetic elimination of behavioral sensitiza-tion in mice lacking calmodulin-stimulated adenylyl cyclases
    • Wei, F., Qiu, C. S., Kim, S. J., Muglia, L., Maas, J. W., Pineda, V. V., et al. (2002b). Genetic elimination of behavioral sensitiza-tion in mice lacking calmodulin-stimulated adenylyl cyclases. Neuron 36, 713-726.
    • (2002) Neuron , vol.36 , pp. 713-726
    • Wei, F.1    Qiu, C.S.2    Kim, S.J.3    Muglia, L.4    Maas, J.W.5    Pineda, V.V.6
  • 108
    • 32544449280 scopus 로고    scopus 로고
    • Calcium calmodulin-stimulated adenylyl cyclases contribute to activation of extracellular signal-regulated kinase in spinal dorsal hornneuronsinadultratsand mice
    • Wei, F., Vadakkan, K. I., Toyoda, H., Wu, L. J., Zhao, M. G., Xu, H., et al. (2006). Calcium calmodulin-stimulated adenylyl cyclases contribute to activation of extracellular signal-regulated kinase in spinal dorsal hornneuronsinadultratsand mice. J. Neurosci. 26, 851-861.
    • (2006) J. Neurosci. , vol.26 , pp. 851-861
    • Wei, F.1    Vadakkan, K.I.2    Toyoda, H.3    Wu, L.J.4    Zhao, M.G.5    Xu, H.6
  • 109
    • 32544448949 scopus 로고    scopus 로고
    • A signaling mechanism from G alpha q-protein-coupled metabotropicglutamatereceptors to gene expression: role of the c-Jun N-terminal kinase pathway
    • Yang, L., Mao, L., Chen, H., Catavsan, M., Kozinn, J., Arora, A., et al. (2006). A signaling mechanism from G alpha q-protein-coupled metabotropicglutamatereceptors to gene expression: role of the c-Jun N-terminal kinase pathway. J. Neurosci. 26, 971-980.
    • (2006) J. Neurosci. , vol.26 , pp. 971-980
    • Yang, L.1    Mao, L.2    Chen, H.3    Catavsan, M.4    Kozinn, J.5    Arora, A.6
  • 110
    • 23744492534 scopus 로고    scopus 로고
    • Deficits in trace fear memory and long-term potentiation in a mouse model for fragile X syndrome
    • Zhao, M.G., Toyoda, H., Ko, S.W., Ding, H. K., Wu, L.J., and Zhuo, M. (2005). Deficits in trace fear memory and long-term potentiation in a mouse model for fragile X syndrome. J. Neurosci. 25, 7385-7392.
    • (2005) J. Neurosci. , vol.25 , pp. 7385-7392
    • Zhao, M.G.1    Toyoda, H.2    Ko, S.W.3    Ding, H.K.4    Wu, L.J.5    Zhuo, M.6
  • 111
    • 14944378161 scopus 로고    scopus 로고
    • Canadian association of neuroscience review: cellular and synaptic insights into physiological and pathological pain. EJLB-CIHR Michael Smith Chair in neu-rosciences and mental health lecture
    • Zhuo, M. (2005). Canadian association of neuroscience review: cellular and synaptic insights into physiological and pathological pain. EJLB-CIHR Michael Smith Chair in neu-rosciences and mental health lecture. Can. J. Neurol. Sci. 32, 27-36.
    • (2005) Can. J. Neurol. Sci. , vol.32 , pp. 27-36
    • Zhuo, M.1
  • 112
    • 41249093870 scopus 로고    scopus 로고
    • Cortical excitation and chronic pain
    • Zhuo, M. (2008). Cortical excitation and chronic pain. Trends Neurosci. 31, 199-207.
    • (2008) Trends Neurosci , vol.31 , pp. 199-207
    • Zhuo, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.