Metabotropic glutamate receptor 5-regulated Elk-1 phosphorylation and immediate early gene expression in striatal neurons

Journal of Neurochemistry

Volumn 85, Issue 4, 2003, Pages 1006-1017

  Mao, Limin ^a   Wang, John Q ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

Author keywords

AMPA; c fos; Calcium; CHPG; GABA; NMDA

Indexed keywords

AMPA RECEPTOR; ANTISENSE OLIGONUCLEOTIDE; CALCIUM CHANNEL L TYPE; CALCIUM ION; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR 5; N METHYL DEXTRO ASPARTIC ACID; PHOSPHOLIPASE C; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ELK 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORPUS STRIATUM; EMBRYO; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GLIA CELL; IMMUNOCYTOCHEMISTRY; IN SITU HYBRIDIZATION; NERVE CELL CULTURE; NERVE CELL PLASTICITY; NEUROCHEMISTRY; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

ANIMALIA; CERVUS ELAPHUS;

EID: 0038587594     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.01750.x     Document Type: Article

References (56)

1. Berridge M. J. (1993) Inositol triphosphate and calcium signaling. Nature 361, 315-325.
2. 2+ rises in hippocampal pyramidal cells. J. Neurosci. 81, 2903-2913.
3. Bordi F. and Ugolini A. (1999) Group I metabotropic glutamate receptors: implications for brain diseases. Prog. Neurobiol. 59, 55-79.
4. Cammarota M., Bevilaqua L. R., Ardenghi P., Paratcha G., Levi de Stein M., Izquierdo I. and Medina J. H. (2000) Learning-associated activation of nuclear MAPK, CREB and Elk-1, along with Fos production, in the rat hippocampus after a one-trial avoidance leaming: abolition by NMDA receptor blockade. Mol. Brain Res. 76, 36-46.
5. Castognuay A. and Robitaille R. (2002) Xestospongin C is a potent inhibitor of SERCA at a vertebrate synapse. Cell Calcium 32, 39-47.
6. Chiamulera C., Epping-Jordan M. P., Zocchi A., Marcon C., Cottiny C., Tacconi S., Corsi M., Orzi F. and Conquet F. (2001) Reinforcing and locomotor stimulant effects of cocaine are absent in mGluR5 null mutant mice. Nat. Neurosci. 4, 873-874.
7. Choe E. S. and McGinty J. F. (2000) N-methyl-D-aspartate receptors and p38 mitogen-activated protein kinase are required for cAMPdependent cyclase response element binding protein and Elk-1 phosphorylation in the striatum. Neuroscience 101, 607-617.
8. Choe E. S. and Wang J. Q. (2001) Group I metabotropic glutamate receptor activation increases phosphorylation of cAMP response element-binding protein, Elk-1, and extracellular signal-regulated kinases in rat dorsal striatum. Mol. Brain Res. 94, 75-84.
9. Choe E. S. and Wang J. Q. (2002) Regulation of transcription factor phosphorylation by metabotropic glutamate receptor-associated signaling pathways in rat striatal neurons. Neuroscience 114, 557-565.
10. Cole R. L., Konradi C., Douglass J. and Hyman S. E. (1995) Neuronal adaptation to amphetamine and dopamine: molecular mechanisms of prodynorphin gene regulation in rat striatum. Neuron 14, 813-823.
11. Congar P., Leinekugel X., Ben-Ari Y. and Crepel V. (1997) A longlasting calcium-activated non-selective cationic current is generated by synaptic stimulation or exogenous activation of group I metabotropic glutamate receptors in CA1 pyramidal neurons. J. Neurosci. 17, 5366-5379.
12. Conn P. J. and Pin J. P. (1997) Pharmacology and function of metabotropic glutamate receptors. Annu. Rev. Pharmacol. Toxicol. 37, 205-237.
13. Dalton S. and Treisman R. (1992) Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum element. Cell 68, 597-612.
14. Das S., Grunert M., Williams L. and Vincent S. R. (1997) NMDA and D1 receptors regulate the phosphorylation of CREB and the induction of c-fos in striatal neurons in primary culture. Synapse 25, 227-233.
15. 2+ pumps. Cell Calcium 26, 9-13.
16. Dolmetsch R. F., Pajvani U., Spotts F. K. and Greenberg. M. E. (2001) Signaling to the nucleus by an L-type calcium channel-calmodulin complex through the MAP kinase pathway. Science 294, 333-339.
17. Gille H., Sharrocks A. D. and Shaw P. E. (1992) Phosphorylation of transcription factor p62TCF by MAP kinase stimulates ternary complex formation at c-fos promotor. Nature 358, 414-417.
18. Gille H., Kortenjann M., Thoma O., Moomaw C., Slaughter C., Cobb M. and Shaw P. E. (1995) ERK phosphorylation potentiates Elk-1mediated ternary complex formation and transactivation. EMBO J. 14, 951-962.
19. Giovane A., Pintzas A., Maira S. M., Sobieszczuk P. and Wasylyk B. (1994) Net, a new ets transcription factor that is activated by ras. Genes Dev. 8, 1502-1513.
20. Grevin D., Ung S., Denhez F., Dehem M., Quatannens B., Begue A., Stehelin D. and Martin P. (1996) Structure and organization of the mouse elkl gene. Gene 174, 185-188.
21. Haak L. L., Song L. S., Molinski T. F., Pessah I. N., Cheng H. and Russell J. T. (2001) Sparks and puffs in oligodendrocyte progenitors: cross talk between ryanodine, receptors and inositol trisphosphate receptors. J. Neurosci. 21, 3860-3870.
22. Hill C. S., Marais R., Wynne J. J., Dalton S. and Treisman R. (1993) Functional analysis of a growth factor-responsive transcription factor complex. Cell 73, 395-406.
23. Hipskind R. A., Rao V. N., Mueller C. G. F., Reddy E. S. P. and Nordheim A. (1991) Ets-related protein Elk-1 is homologous to the c-fos regulatory factor p62TCF. Nature 354, 531-534.
24. Hipskind R. A., Baccarini M. and Nordheim A. (1994) Transient activation of RAF-1, MEK, and ERK2 coincides kinetically with ternary complex factor phosphorylation and immediate-early gene promoter activity in vivo. Mol. Cell. Biol. 14, 6219-6231.
25. 2+ mobilizing mechanisms in cultured rat cerebellar granule cells. J. Physiol. 456, 667-680.
26. Kerner J. A., Standaert D. G., Penney J. B., Young A. B. Jr and Landwehrmeyer G. B. (1997) Expression of group one metabotropic receptor subunit mRNAs in neurochemically identified neurons in the rat neostriatum, neocortex, and hippocampus. Mol. Brain Res. 48, 259-269.
27. Kridger P., Hellgren-Kotaleski J., Kettunen P. and El Manira A. J. (2000) Interaction between metabotropic and ionotropic glutamate receptors regulates neuronal network activity. J. Neurosci. 20, 5382-5391.
28. Kurino M., Fukunaga K., Ushio Y. and Miyamoto E. (1995) Activation of mitogen-activated protein kinase in cultured rat hippocampal neurons by stimulation of glutamate receptors. J. Neurochem. 65, 1282-1289.
29. Lan J. Y., Skeberdis V. A., Jover T., Zheng X., Bennett M. V. and Zukin R. S. (2001) Activation of metabotropic glutamate receptor 1 accelerates NMDA receptor trafficking. J. Neurosci. 21, 6058-6068.
30. Li R., Pei H. and Watson D. K. (2000) Regulation of Ets function by protein-protein interactions. Oncogene 19, 6514-6523.
31. Liu F. C. and Graybiel A. M. (1998) Region-dependent dynamics of cAMP response element-binding protein phosphorylation in the basal ganglia. Proc. Natl Acad. Sci. USA 95, 4708-4713.
32. Lopez M., Oettgen P., Akbarali Y., Dendorfer U. and Liberman T. A. (1994) ERP, a new member of the ets transcription factor/oncoprotein family: cloning, characterization and differential expression during B-cell development. Mol. Cell. Biol. 14, 3292-3309.
33. Macias W., Carlson R., Rajadhyaksha A., Barczak A. and Konradi C. (2001) Potassium chloride depolarization mediates CREB phosphorylation in striatal neurons in an NMDA receptor-dependent manner. Brain Res. 890, 222-232.
34. Mao L. and Wang J. Q. (2001) Upregulation of preprodynorphin and preproenkephalin mRNA expression by selective activation of group I metabotropic glutamate receptors in characterized primary cultures of rat striatal neurons. Mol. Brain Res. 86, 125-137.
35. Mao L. and Wang J. Q. (2002a) Glutamate cascade to cAMP response element-binding protein phosphorylation in cultured striatal neurons through calcium-coupled group I mGluRs. Mol. Pharmacol. 62, 473-484.
36. Mao L. and Wang J. Q. (2002b) Phosphorylation of cAMP response element-binding protein in cultured striatal neurons by metabotropic glutamate receptor subtype 5. J. Neurochem. 84, 233-243.
37. Martone M. E., Alba S. A., Edelman V. M., Airey J. A. and Ellisman M. H. (1997) Distribution of inositol-1,4,5-trisphosphate and ryanodine receptors in rat neostriatum. Brain Res. 756, 9-21.
38. Mulvaney J. M., Zhang T., Fewtrell C. and Roberson M. S. (1999) Calcium influx through L-type channels is required for selective activation of extracellular signal-regulated kinase by gonadotropinreleasing hormone. J. Biol. Chem. 274, 29796-29804.
39. Nakanishi S. and Masu M. (1994) Molecular diversity and functions of glutamate receptors. Annu. Rev Biophys. Biomol. Struc. 23, 319348.
40. Pintor A., Pezzola A., Reggio R., Quarta D. and Popoli P. (2000) The mGlu5 receptor agonist CHPG stimulates striatal glutamate release: possible involvement of A2A receptors. Neuroreport 11, 3611-3614.
41. Pisani A., Gubellini P., Bonsi P., Conquet F., Picconi B., Centonze D., Bernardi G. and Calabresi P. (2001) Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-D-aspartate responses in medium spiny striatal neurons. Neuroscience 106, 579-587.
42. Prothero L. S., Mathie A. and Richards C. D. (2000) Purinergic and muscarinic receptor activation activates a common calcium entry pathway in rat neocortical neurons and glial cells. Neuropharmacology 39, 1768-1778.
43. 2+ signaling in rat hippocampal neurons. J. Neurosci. 20, 8628-8636.
44. 2+ channels are essential for glutamate-mediated CREB phosphorylation and c-fos gene expression in striatal neurons. J. Neurosci. 19, 6348-6359.
45. Sgambato V., Pages C., Rogard M., Besson M. J. and Caboche J. (1998a) Extracellular signal-regulated kinase (ERK) controls immediate early gene induction on corticostriatal stimulation. J. Neurosci. 18, 8814-8825.
46. Sgambato V., Vanhoutte P., Pages C., Rogard M., Hipskind R., Besson M. J. and Caboche J. (1998b) In vivo expression and regulation of Elk-1, a target of the extracellular-regulated kinase signaling pathway, in the adult rat brain. J. Neurosci. 18, 214-226.
47. Sharrocks A. D. (2001) The ETS-domain transcription factor family. Nat. Rev. Mol. Cell Biol. 2, 827-837.
48. Skeberdis V. A., Lan J., Opitz T., Zheng X., Bennett M. V. and Zukin R. S. (2001) mGluR1-mediated potentiation of NMDA receptors involves a rise in intracellular calcium and activation of protein kinase C. Neuropharmacology 40, 856-865.
49. Sung K. W., Choi S. and Lovinger D. M. (2001) Activation of group I mGluRs is necessary for induction of long-term depression at striatal synapses. J. Neurophysiol. 86, 2405-2412.
50. Testa C. M., Standaert D. G., Landwehrmeyer G. B., Penney J. B. Jr and Young A. B. (1995) Differential expression of mGluR5 metabotropic glutamate receptor mRNA by rat striatal neurons. J. Comp. Neurol. 354, 241-252.
51. Treisman R. (1992) The serum response element. Trends Biochem. Sci. 17, 423-426.
52. Vanhoutte P., Barnier J. V., Guibert B., Pages C., Besson M. J., Hipskind R. A. and Caboche J. (1999) Glutamate induces phosphorylation of Elk-1 and CREB, along with c-fos activation, via an extracellular signal-regulated kinase-dependent pathway in brain slices. Mol. Cell Biol. 19, 136-146.
53. Wang J. Q., Mao L. and Lau Y. S. (2002) Glutamate cascade from metabotropic glutamate receptors to gene expression in striatal neurons. In: Implications for Psychostimulant Dependence and Medication, in Glutamate and Addiction (Herman B. H., ed.), pp. 157-170. Humana Press, New Jersey.
54. Xia Z., Dudek H., Miranti C. K. and Greenberg M. E. (1996) Calcium influx via the NMDA receptor induces immediate early gene transcription by a MAP kinase/ERK-dependent mechanism. J. Neurosci. 16, 5425-5436.
55. Yordy J. S. and Muise-Helmericks R. C. (2000) Signal transduction and the Ets family of transcription factors. Oncogene 19, 6503-6513.
56. Zinck R., Cahill M. A., Kracht M., Sachsenmaier C., Hipskind R. A. and Nordheim A. (1995) Protein synthesis inhibitors reveal differential regulation of mitogen-activated protein kinase and stress-activated protein kinase pathways that converge on Elk-1. Mol. Cell Biol. 15, 4930-4938.