Involvement of de novo ceramide synthesis in gamma-tocopherol and gamma-tocotrienol-induced apoptosis in human breast cancer cells

Molecular Nutrition and Food Research

Volumn 56, Issue 12, 2012, Pages 1803-1811

  Gopalan, Archana ^a   Yu, Weiping ^b   Jiang, Qing ^c   Jang, Yumi ^c   Sanders, Bob G ^b   Kline, Kimberly ^a  

^a The University of Texas at Austin   (United States)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^c PURDUE UNIVERSITY   (United States)

Author keywords

Apoptosis; Ceramide; Gamma tocopherol; Gamma tocotrienol; Human breast cancer cells

Indexed keywords

ALPHA TOCOPHEROL; CERAMIDE; CHROMAN DERIVATIVE; DDIT3 PROTEIN, HUMAN; DRUG DERIVATIVE; GAMMA TOCOPHEROL; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; PLASTOCHROMANOL 8; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; TNFRSF10B PROTEIN, HUMAN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR;

APOPTOSIS; ARTICLE; BIOSYNTHESIS; BREAST TUMOR; CELL STRAIN MCF 7; DRUG EFFECT; FEMALE; GENETICS; HUMAN; ISOLATION AND PURIFICATION; LIQUID CHROMATOGRAPHY; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; TANDEM MASS SPECTROMETRY; TUMOR CELL LINE; UPREGULATION; WESTERN BLOTTING;

APOPTOSIS; BLOTTING, WESTERN; BREAST NEOPLASMS; CELL LINE, TUMOR; CERAMIDES; CHROMANS; CHROMATOGRAPHY, LIQUID; FEMALE; GAMMA-TOCOPHEROL; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MCF-7 CELLS; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TANDEM MASS SPECTROMETRY; TRANSCRIPTION FACTOR CHOP; UP-REGULATION; VITAMIN E;

EID: 84870713976     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201200350     Document Type: Article

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