메뉴 건너뛰기




Volumn 150, Issue 1-3, 2012, Pages 229-235

Zinc supplementation attenuates high glucose-induced epithelial-to- mesenchymal transition of peritoneal mesothelial cells

Author keywords

Epithelial to mesenchymal transition; High glucose; Mitogen activated protein kinase; Rat peritoneal mesothelial cells; Smad; Zinc

Indexed keywords

GLUCOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; REACTIVE OXYGEN METABOLITE; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; ZINC SULFATE;

EID: 84870685973     PISSN: 01634984     EISSN: 15590720     Source Type: Journal    
DOI: 10.1007/s12011-012-9451-4     Document Type: Article
Times cited : (16)

References (41)
  • 2
    • 20544446404 scopus 로고    scopus 로고
    • Transient overexpression of TGF-{beta}1 induces epithelial mesenchymal transition in the rodent peritoneum
    • 15590759 10.1681/ASN.2004060436 1:CAS:528:DC%2BD2MXhvVCksbY%3D
    • Margetts PJ, Bonniaud P, Liu L, Hoff CM, Holmes CJ, West-Mays JA et al (2005) Transient overexpression of TGF-{beta}1 induces epithelial mesenchymal transition in the rodent peritoneum. J Am Soc Nephrol 16:425-436
    • (2005) J Am Soc Nephrol , vol.16 , pp. 425-436
    • Margetts, P.J.1    Bonniaud, P.2    Liu, L.3    Hoff, C.M.4    Holmes, C.J.5    West-Mays, J.A.6
  • 3
    • 0035123267 scopus 로고    scopus 로고
    • Biocompatibility of new peritoneal dialysis solutions: What can we hope to achieve?
    • 11229614
    • Chung SH, Stenvinkel P, Bergstrom J, Lindholm B (2000) Biocompatibility of new peritoneal dialysis solutions: what can we hope to achieve? Perit Dial Int 20(Suppl 5):S57-S67
    • (2000) Perit Dial Int , vol.20 , Issue.SUPPL. 5
    • Chung, S.H.1    Stenvinkel, P.2    Bergstrom, J.3    Lindholm, B.4
  • 4
    • 0035135641 scopus 로고    scopus 로고
    • High glucose-induced PKC activation mediates TGF-beta 1 and fibronectin synthesis by peritoneal mesothelial cells
    • 11168928 10.1046/j.1523-1755.2001.059002463.x 1:CAS:528: DC%2BD3MXhtlKis7o%3D
    • Ha H, Yu MR, Lee HB (2001) High glucose-induced PKC activation mediates TGF-beta 1 and fibronectin synthesis by peritoneal mesothelial cells. Kidney Int 59:463-470
    • (2001) Kidney Int , vol.59 , pp. 463-470
    • Ha, H.1    Yu, M.R.2    Lee, H.B.3
  • 5
    • 0031905963 scopus 로고    scopus 로고
    • Effect of glucose concentration, osmolality, and sterilization process of peritoneal dialysis fluids on cytokine production by peripheral blood mononuclear cells and polymorphonuclear cell functions in vitro
    • 9469498 10.1053/ajkd.1998.v31.pm9469498 1:CAS:528:DyaK1cXht1arur4%3D
    • Cendoroglo M, Sundaram S, Jaber BL, Pereira BJ (1998) Effect of glucose concentration, osmolality, and sterilization process of peritoneal dialysis fluids on cytokine production by peripheral blood mononuclear cells and polymorphonuclear cell functions in vitro. Am J Kidney Dis 31:273-282
    • (1998) Am J Kidney Dis , vol.31 , pp. 273-282
    • Cendoroglo, M.1    Sundaram, S.2    Jaber, B.L.3    Pereira, B.J.4
  • 6
    • 48249109924 scopus 로고    scopus 로고
    • The role of the TGF/Smad signaling pathway in peritoneal fibrosis induced by peritoneal dialysis solutions
    • 18600031 10.1159/000142529 1:CAS:528:DC%2BD1cXptVyisbs%3D
    • Yao Q, Pawlaczyk K, Ayala ER, Styszynski A, Breborowicz A, Heimburger O et al (2008) The role of the TGF/Smad signaling pathway in peritoneal fibrosis induced by peritoneal dialysis solutions. Nephron Exp Nephrol 109:e71-e78
    • (2008) Nephron Exp Nephrol , vol.109
    • Yao, Q.1    Pawlaczyk, K.2    Ayala, E.R.3    Styszynski, A.4    Breborowicz, A.5    Heimburger, O.6
  • 7
    • 62149135860 scopus 로고    scopus 로고
    • HGF and BMP-7 ameliorate high glucose-induced epithelial-to-mesenchymal transition of peritoneal mesothelium
    • 19193779 10.1681/ASN.2008040424 1:CAS:528:DC%2BD1MXktVemsb0%3D
    • Yu MA, Shin KS, Kim JH, Kim YI, Chung SS, Park SH et al (2009) HGF and BMP-7 ameliorate high glucose-induced epithelial-to-mesenchymal transition of peritoneal mesothelium. J Am Soc Nephrol 20:567-581
    • (2009) J Am Soc Nephrol , vol.20 , pp. 567-581
    • Yu, M.A.1    Shin, K.S.2    Kim, J.H.3    Kim, Y.I.4    Chung, S.S.5    Park, S.H.6
  • 8
    • 33846829571 scopus 로고    scopus 로고
    • Oxidative stress contributes to accelerated development of the senescent phenotype in human peritoneal mesothelial cells exposed to high glucose
    • 17291987 10.1016/j.freeradbiomed.2006.12.002 1:CAS:528: DC%2BD2sXhs1Smu74%3D
    • Ksiazek K, Breborowicz A, Jorres A, Witowski J (2007) Oxidative stress contributes to accelerated development of the senescent phenotype in human peritoneal mesothelial cells exposed to high glucose. Free Radic Biol Med 42:636-641
    • (2007) Free Radic Biol Med , vol.42 , pp. 636-641
    • Ksiazek, K.1    Breborowicz, A.2    Jorres, A.3    Witowski, J.4
  • 9
    • 33745272219 scopus 로고    scopus 로고
    • Oxidative stress during peritoneal dialysis: Implications in functional and structural changes in the membrane
    • 16641917 10.1038/sj.ki.5001506 1:CAS:528:DC%2BD28XkvVyrtrw%3D
    • Noh H, Kim JS, Han KH, Lee GT, Song JS, Chung SH et al (2006) Oxidative stress during peritoneal dialysis: implications in functional and structural changes in the membrane. Kidney Int 69:2022-2028
    • (2006) Kidney Int , vol.69 , pp. 2022-2028
    • Noh, H.1    Kim, J.S.2    Han, K.H.3    Lee, G.T.4    Song, J.S.5    Chung, S.H.6
  • 10
    • 0029060897 scopus 로고
    • The function of metallothionein
    • 7655345 10.1016/0197-0186(94)00165-Q 1:CAS:528:DyaK2MXmsFylsbw%3D
    • Vallee BL (1995) The function of metallothionein. Neurochem Int 27:23-33
    • (1995) Neurochem Int , vol.27 , pp. 23-33
    • Vallee, B.L.1
  • 11
    • 0027394031 scopus 로고
    • The biochemical basis of zinc physiology
    • 8419966 10.2466/pr0.1993.73.1.79 1:CAS:528:DyaK3sXhvVyhtrY%3D
    • Vallee BL, Falchuk KH (1993) The biochemical basis of zinc physiology. Physiol Rev 73:79-118
    • (1993) Physiol Rev , vol.73 , pp. 79-118
    • Vallee, B.L.1    Falchuk, K.H.2
  • 12
    • 34250362384 scopus 로고    scopus 로고
    • Possible inhibitory effect of oral zinc supplementation on hepatic fibrosis through downregulation of TIMP-1: A pilot study
    • 17539814 10.1111/j.1872-034X.2007.00065.x 1:CAS:528:DC%2BD2sXotVCgsrw%3D
    • Takahashi M, Saito H, Higashimoto M, Hibi T (2007) Possible inhibitory effect of oral zinc supplementation on hepatic fibrosis through downregulation of TIMP-1: a pilot study. Hepatol Res 37:405-409
    • (2007) Hepatol Res , vol.37 , pp. 405-409
    • Takahashi, M.1    Saito, H.2    Higashimoto, M.3    Hibi, T.4
  • 13
    • 85047692717 scopus 로고    scopus 로고
    • Alcohol-induced myocardial fibrosis in metallothionein-null mice: Prevention by zinc supplementation
    • 16049321 10.1016/S0002-9440(10)62979-3 1:CAS:528:DC%2BD2MXpsVeqsbk%3D
    • Wang L, Zhou Z, Saari JT, Kang YJ (2005) Alcohol-induced myocardial fibrosis in metallothionein-null mice: prevention by zinc supplementation. Am J Pathol 167:337-344
    • (2005) Am J Pathol , vol.167 , pp. 337-344
    • Wang, L.1    Zhou, Z.2    Saari, J.T.3    Kang, Y.J.4
  • 14
    • 58149218447 scopus 로고    scopus 로고
    • Causes and consequences of zinc dyshomeostasis in rats with chronic aldosteronism
    • 18806605 10.1097/FJC.0b013e3181833eb8 1:CAS:528:DC%2BD1cXhtFers73K
    • Gandhi MS, Deshmukh PA, Kamalov G, Zhao T, Zhao W, Whaley JT et al (2008) Causes and consequences of zinc dyshomeostasis in rats with chronic aldosteronism. J Cardiovasc Pharmacol 52:245-252
    • (2008) J Cardiovasc Pharmacol , vol.52 , pp. 245-252
    • Gandhi, M.S.1    Deshmukh, P.A.2    Kamalov, G.3    Zhao, T.4    Zhao, W.5    Whaley, J.T.6
  • 16
    • 0014706068 scopus 로고
    • Zinc, copper, magnesium and calcium in dialyzed and nondialyzed uremic patients
    • 5410656 10.1001/archinte.1970.00310010090007 1:CAS:528: DyaE3cXovVagtQ%3D%3D
    • Mansouri K, Halsted JA, Gombos EA (1970) Zinc, copper, magnesium and calcium in dialyzed and nondialyzed uremic patients. Arch Intern Med 125:88-93
    • (1970) Arch Intern Med , vol.125 , pp. 88-93
    • Mansouri, K.1    Halsted, J.A.2    Gombos, E.A.3
  • 17
    • 0020693478 scopus 로고
    • Comparison of trace elements in peritoneal dialysis, hemodialysis, and uremia
    • 6834697 10.1038/ki.1983.3 1:STN:280:DyaL3s7msFWluw%3D%3D
    • Thomson NM, Stevens BJ, Humphery TJ, Atkins RC (1983) Comparison of trace elements in peritoneal dialysis, hemodialysis, and uremia. Kidney Int 23:9-14
    • (1983) Kidney Int , vol.23 , pp. 9-14
    • Thomson, N.M.1    Stevens, B.J.2    Humphery, T.J.3    Atkins, R.C.4
  • 18
    • 0032832982 scopus 로고    scopus 로고
    • Trace elements in end-stage renal disease. 1. Methodological aspects and the influence of water treatment and dialysis equipment
    • 10494020 10.1159/000014394 1:CAS:528:DyaK1MXmtVOitbs%3D
    • Zima T, Tesar V, Mestek O, Nemecek K (1999) Trace elements in end-stage renal disease. 1. Methodological aspects and the influence of water treatment and dialysis equipment. Blood Purif 17:182-186
    • (1999) Blood Purif , vol.17 , pp. 182-186
    • Zima, T.1    Tesar, V.2    Mestek, O.3    Nemecek, K.4
  • 19
    • 0026649796 scopus 로고
    • Trace elements in dialysis fluids and assessment of the exposure of patients on regular hemodialysis, hemofiltration and continuous ambulatory peritoneal dialysis
    • 1501743 10.1159/000186964 1:STN:280:DyaK38zmsF2jug%3D%3D
    • Padovese P, Gallieni M, Brancaccio D, Pietra R, Fortaner S, Sabbioni E et al (1992) Trace elements in dialysis fluids and assessment of the exposure of patients on regular hemodialysis, hemofiltration and continuous ambulatory peritoneal dialysis. Nephron 61:442-448
    • (1992) Nephron , vol.61 , pp. 442-448
    • Padovese, P.1    Gallieni, M.2    Brancaccio, D.3    Pietra, R.4    Fortaner, S.5    Sabbioni, E.6
  • 20
    • 0036720650 scopus 로고    scopus 로고
    • Independent effects of residual renal function and dialysis adequacy on dietary micronutrient intakes in patients receiving continuous ambulatory peritoneal dialysis
    • 12198001 1:CAS:528:DC%2BD38XmslSntrs%3D
    • Wang AY, Sea MM, Ip R, Law MC, Chow KM, Lui SF et al (2002) Independent effects of residual renal function and dialysis adequacy on dietary micronutrient intakes in patients receiving continuous ambulatory peritoneal dialysis. Am J Clin Nutr 76:569-576
    • (2002) Am J Clin Nutr , vol.76 , pp. 569-576
    • Wang, A.Y.1    Sea, M.M.2    Ip, R.3    Law, M.C.4    Chow, K.M.5    Lui, S.F.6
  • 22
    • 39849091107 scopus 로고    scopus 로고
    • Spectrophotometric and colorimetric determination of protein concentration
    • Chapter 10: Unit 10 11A
    • Simonian MH, Smith JA (2006) Spectrophotometric and colorimetric determination of protein concentration. Curr Protoc Mol Biol Chapter 10: Unit 10 11A
    • (2006) Curr Protoc Mol Biol
    • Simonian, M.H.1    Smith, J.A.2
  • 23
    • 48749112189 scopus 로고    scopus 로고
    • Transforming growth factor {beta}1 induces epithelial-mesenchymal transition by activating the JNK-Smad3 pathway in rat peritoneal mesothelial cells
    • 18552272 1:CAS:528:DC%2BD1cXpvVyqtro%3D
    • Liu Q, Mao H, Nie J, Chen W, Yang Q, Dong X et al (2008) Transforming growth factor {beta}1 induces epithelial-mesenchymal transition by activating the JNK-Smad3 pathway in rat peritoneal mesothelial cells. Perit Dial Int 28(Suppl 3):S88-S95
    • (2008) Perit Dial Int , vol.28 , Issue.SUPPL. 3
    • Liu, Q.1    Mao, H.2    Nie, J.3    Chen, W.4    Yang, Q.5    Dong, X.6
  • 24
    • 42149155984 scopus 로고    scopus 로고
    • Clinical, immunological, anti-inflammatory and antioxidant roles of zinc
    • 18054190 10.1016/j.exger.2007.10.013 1:CAS:528:DC%2BD1cXkvFCqtbg%3D
    • Prasad AS (2008) Clinical, immunological, anti-inflammatory and antioxidant roles of zinc. Exp Gerontol 43:370-377
    • (2008) Exp Gerontol , vol.43 , pp. 370-377
    • Prasad, A.S.1
  • 25
    • 33845415089 scopus 로고    scopus 로고
    • Zinc modulates cytokine-induced lung epithelial cell barrier permeability
    • 16844947 10.1152/ajplung.00207.2006 1:CAS:528:DC%2BD2sXjvFCk
    • Bao S, Knoell DL (2006) Zinc modulates cytokine-induced lung epithelial cell barrier permeability. Am J Physiol Lung Cell Mol Physiol 291:L1132-L1141
    • (2006) Am J Physiol Lung Cell Mol Physiol , vol.291
    • Bao, S.1    Knoell, D.L.2
  • 26
    • 0032720129 scopus 로고    scopus 로고
    • Bifidobacterium animalis protects intestine from damage induced by zinc deficiency in rats
    • 10573559 1:CAS:528:DyaK1MXns1yju7o%3D
    • Mengheri E, Nobili F, Vignolini F, Pesenti M, Brandi G, Biavati B (1999) Bifidobacterium animalis protects intestine from damage induced by zinc deficiency in rats. J Nutr 129:2251-2257
    • (1999) J Nutr , vol.129 , pp. 2251-2257
    • Mengheri, E.1    Nobili, F.2    Vignolini, F.3    Pesenti, M.4    Brandi, G.5    Biavati, B.6
  • 27
    • 0015817227 scopus 로고
    • Effect of zinc deficiency on nucleic acids, collagen, and noncollagenous protein of the connective tissue
    • 4758743 1:CAS:528:DyaE2cXks1Krug%3D%3D
    • Fernandez-Madrid F, Prasad AS, Oberleas D (1973) Effect of zinc deficiency on nucleic acids, collagen, and noncollagenous protein of the connective tissue. J Lab Clin Med 82:951-961
    • (1973) J Lab Clin Med , vol.82 , pp. 951-961
    • Fernandez-Madrid, F.1    Prasad, A.S.2    Oberleas, D.3
  • 28
    • 1642463525 scopus 로고    scopus 로고
    • Reactive oxygen species amplify protein kinase C signaling in high glucose-induced fibronectin expression by human peritoneal mesothelial cells
    • 15086456 10.1111/j.1523-1755.2004.00491.x 1:CAS:528:DC%2BD2cXjtFyqtL8%3D
    • Lee HB, Yu MR, Song JS, Ha H (2004) Reactive oxygen species amplify protein kinase C signaling in high glucose-induced fibronectin expression by human peritoneal mesothelial cells. Kidney Int 65:1170-1179
    • (2004) Kidney Int , vol.65 , pp. 1170-1179
    • Lee, H.B.1    Yu, M.R.2    Song, J.S.3    Ha, H.4
  • 29
    • 0028915120 scopus 로고
    • Zinc deficiency causes oxidative damage to proteins, lipids and DNA in rat testes
    • 7722683 1:CAS:528:DyaK2MXkvVKrt78%3D
    • Oteiza PI, Olin KL, Fraga CG, Keen CL (1995) Zinc deficiency causes oxidative damage to proteins, lipids and DNA in rat testes. J Nutr 125:823-829
    • (1995) J Nutr , vol.125 , pp. 823-829
    • Oteiza, P.I.1    Olin, K.L.2    Fraga, C.G.3    Keen, C.L.4
  • 30
    • 0037168653 scopus 로고    scopus 로고
    • Low intracellular zinc induces oxidative DNA damage, disrupts p53, NFkappa B, and AP1 DNA binding, and affects DNA repair in a rat glioma cell line
    • 12481036 10.1073/pnas.222679399 1:CAS:528:DC%2BD3sXhvV2hsQ%3D%3D
    • Ho E, Ames BN (2002) Low intracellular zinc induces oxidative DNA damage, disrupts p53, NFkappa B, and AP1 DNA binding, and affects DNA repair in a rat glioma cell line. Proc Natl Acad Sci USA 99:16770-16775
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 16770-16775
    • Ho, E.1    Ames, B.N.2
  • 31
    • 50949093099 scopus 로고    scopus 로고
    • Zinc supplementation decreases oxidative stress, incidence of infection, and generation of inflammatory cytokines in sickle cell disease patients
    • 18674741 10.1016/j.trsl.2008.06.001 1:CAS:528:DC%2BD1cXpt1Kit7Y%3D
    • Bao B, Prasad AS, Beck FW, Snell D, Suneja A, Sarkar FH et al (2008) Zinc supplementation decreases oxidative stress, incidence of infection, and generation of inflammatory cytokines in sickle cell disease patients. Transl Res 152:67-80
    • (2008) Transl Res , vol.152 , pp. 67-80
    • Bao, B.1    Prasad, A.S.2    Beck, F.W.3    Snell, D.4    Suneja, A.5    Sarkar, F.H.6
  • 32
    • 53149083386 scopus 로고    scopus 로고
    • Zinc deficiency impairs neuronal precursor cell proliferation and induces apoptosis via p53-mediated mechanisms
    • 18778698 10.1016/j.brainres.2008.08.040 1:CAS:528:DC%2BD1cXht1SisLjP
    • Corniola RS, Tassabehji NM, Hare J, Sharma G, Levenson CW (2008) Zinc deficiency impairs neuronal precursor cell proliferation and induces apoptosis via p53-mediated mechanisms. Brain Res 1237:52-61
    • (2008) Brain Res , vol.1237 , pp. 52-61
    • Corniola, R.S.1    Tassabehji, N.M.2    Hare, J.3    Sharma, G.4    Levenson, C.W.5
  • 33
    • 0028866179 scopus 로고
    • Differential effects of transforming growth factor-beta on osteoclast-like cell formation in mouse marrow culture: Relation to the effect of zinc-chelating dipeptides
    • 8745062 10.1016/0196-9781(95)02030-6 1:CAS:528:DyaK2MXhtVShsL%2FL
    • Yamaguchi M, Kishi S (1995) Differential effects of transforming growth factor-beta on osteoclast-like cell formation in mouse marrow culture: relation to the effect of zinc-chelating dipeptides. Peptides 16:1483-1488
    • (1995) Peptides , vol.16 , pp. 1483-1488
    • Yamaguchi, M.1    Kishi, S.2
  • 34
    • 65749117033 scopus 로고    scopus 로고
    • Zinc supplementation attenuates ethanol- and acetaldehyde-induced liver stellate cell activation by inhibiting reactive oxygen species (ROS) production and by influencing intracellular signaling
    • 19376089 10.1016/j.bcp.2009.04.009 1:CAS:528:DC%2BD1MXms1WgsLk%3D
    • Szuster-Ciesielska A, Plewka K, Daniluk J, Kandefer-Szerszen M (2009) Zinc supplementation attenuates ethanol- and acetaldehyde-induced liver stellate cell activation by inhibiting reactive oxygen species (ROS) production and by influencing intracellular signaling. Biochem Pharmacol 78:301-314
    • (2009) Biochem Pharmacol , vol.78 , pp. 301-314
    • Szuster-Ciesielska, A.1    Plewka, K.2    Daniluk, J.3    Kandefer-Szerszen, M.4
  • 35
    • 24644480749 scopus 로고    scopus 로고
    • Molecular requirements for epithelial-mesenchymal transition during tumor progression
    • 16098727 10.1016/j.ceb.2005.08.001 1:CAS:528:DC%2BD2MXhtVWnsb7L
    • Huber MA, Kraut N, Beug H (2005) Molecular requirements for epithelial-mesenchymal transition during tumor progression. Curr Opin Cell Biol 17:548-558
    • (2005) Curr Opin Cell Biol , vol.17 , pp. 548-558
    • Huber, M.A.1    Kraut, N.2    Beug, H.3
  • 36
    • 77951953778 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition: From molecular mechanisms, redox regulation to implications in human health and disease
    • 19903090 10.1089/ars.2009.2737 1:CAS:528:DC%2BC3cXls1Wgur8%3D
    • Cannito S, Novo E, di Bonzo LV, Busletta C, Colombatto S, Parola M (2010) Epithelial-mesenchymal transition: from molecular mechanisms, redox regulation to implications in human health and disease. Antioxid Redox Signal 12:1383-1430
    • (2010) Antioxid Redox Signal , vol.12 , pp. 1383-1430
    • Cannito, S.1    Novo, E.2    Di Bonzo, L.V.3    Busletta, C.4    Colombatto, S.5    Parola, M.6
  • 37
    • 0031721232 scopus 로고    scopus 로고
    • Regulation of nuclear factor kappaB by corticosteroids in rat mesangial cells
    • 9727370 1:CAS:528:DyaK1cXlvVagtbo%3D
    • Auwardt RB, Mudge SJ, Chen CG, Power DA (1998) Regulation of nuclear factor kappaB by corticosteroids in rat mesangial cells. J Am Soc Nephrol 9:1620-1628
    • (1998) J Am Soc Nephrol , vol.9 , pp. 1620-1628
    • Auwardt, R.B.1    Mudge, S.J.2    Chen, C.G.3    Power, D.A.4
  • 38
    • 0036847701 scopus 로고    scopus 로고
    • Zinc inhibits nuclear factor-kappa B activation and sensitizes prostate cancer cells to cytotoxic agents
    • 12429649 1:CAS:528:DC%2BD38XpsVCgtbo%3D
    • Uzzo RG, Leavis P, Hatch W, Gabai VL, Dulin N, Zvartau N et al (2002) Zinc inhibits nuclear factor-kappa B activation and sensitizes prostate cancer cells to cytotoxic agents. Clin Cancer Res 8:3579-3583
    • (2002) Clin Cancer Res , vol.8 , pp. 3579-3583
    • Uzzo, R.G.1    Leavis, P.2    Hatch, W.3    Gabai, V.L.4    Dulin, N.5    Zvartau, N.6
  • 39
    • 0035130899 scopus 로고    scopus 로고
    • Dietary zinc supplementation inhibits NFkappaB activation and protects against chemically induced diabetes in CD1 mice
    • 1:CAS:528:DC%2BD3MXpvFyrsw%3D%3D
    • Ho E, Quan N, Tsai YH, Lai W, Bray TM (2001) Dietary zinc supplementation inhibits NFkappaB activation and protects against chemically induced diabetes in CD1 mice. Exp Biol Med (Maywood) 226:103-111
    • (2001) Exp Biol Med (Maywood) , vol.226 , pp. 103-111
    • Ho, E.1    Quan, N.2    Tsai, Y.H.3    Lai, W.4    Bray, T.M.5
  • 40
    • 0141640785 scopus 로고    scopus 로고
    • Zinc modulates PPARgamma signaling and activation of porcine endothelial cells
    • 14519784 1:CAS:528:DC%2BD3sXotFKrsb8%3D
    • Meerarani P, Reiterer G, Toborek M, Hennig B (2003) Zinc modulates PPARgamma signaling and activation of porcine endothelial cells. J Nutr 133:3058-3064
    • (2003) J Nutr , vol.133 , pp. 3058-3064
    • Meerarani, P.1    Reiterer, G.2    Toborek, M.3    Hennig, B.4
  • 41
    • 0038150155 scopus 로고    scopus 로고
    • Zinc-induced NF-kappaB inhibition can be modulated by changes in the intracellular metallothionein level
    • 12878048 10.1016/S0041-008X(03)00167-4 1:CAS:528:DC%2BD3sXls1Cjsb0%3D
    • Kim CH, Kim JH, Lee J, Ahn YS (2003) Zinc-induced NF-kappaB inhibition can be modulated by changes in the intracellular metallothionein level. Toxicol Appl Pharmacol 190:189-196
    • (2003) Toxicol Appl Pharmacol , vol.190 , pp. 189-196
    • Kim, C.H.1    Kim, J.H.2    Lee, J.3    Ahn, Y.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.