Simultaneous inhibition of metastasis and growth of breast cancer by co-delivery of twist shRNA and paclitaxel using pluronic P85-PEI/TPGS complex nanoparticles

Biomaterials

Volumn 34, Issue 5, 2013, Pages 1581-1590

  Shen, Jianan ^a   Sun, Huiping ^a,b   Xu, Pengfei ^a   Yin, Qi ^a   Zhang, Zhiwen ^a   Wang, Siling ^b   Yu, Haijun ^a   Li, Yaping ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Metastasis; Paclitaxel; Pluronic P85; RNA; Twist

Indexed keywords

ANTI-TUMOR EFFICACY; BREAST CANCER; BREAST CANCER CELLS; CELL MIGRATION; CELLULAR UPTAKE; COMPLEX NANOPARTICLES; DOWN-REGULATION; EFFECTIVE THERAPY; IN-VIVO; INHIBITION RATE; INHIBITORY EFFECT; LOW MOLECULAR WEIGHT; METASTASIS; MICE MODELS; PACLITAXEL; PLURONICS; POLYETHYLENEIMINE; PRIMARY SOURCES; RNA INTERFERENCE; SYNERGISTIC EFFECT; TOCOPHERYL POLYETHYLENE GLYCOL 1000 SUCCINATES; TUMOR GROWTH; TWIST;

BIOLOGICAL ORGANS; CELL CULTURE; CHEMOTHERAPY; DISEASES; ENZYME INHIBITION; HYDROGELS; MAMMALS; NANOPARTICLES; POLYETHYLENE GLYCOLS; RNA; TUMORS;

PATHOLOGY;

NANOPARTICLE; PACLITAXEL; PLURONIC P85; POLOXAMER; POLYETHYLENEIMINE; SHORT HAIRPIN RNA; TOCOFERSOLAN; TRANSCRIPTION FACTOR TWIST; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER INHIBITION; CELL INVASION; CELL MIGRATION; DOWN REGULATION; DRUG ACCUMULATION; DRUG DELIVERY SYSTEM; FEMALE; GENE DELIVERY SYSTEM; INTERNALIZATION; LUNG METASTASIS; METASTASIS INHIBITION; MOUSE; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RNA INTERFERENCE;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BREAST NEOPLASMS; CARCINOMA; DRUG COMBINATIONS; FEMALE; GENETIC THERAPY; IMINES; MICE; MICE, INBRED BALB C; MICE, NUDE; NANOCAPSULES; PACLITAXEL; POLOXALENE; POLYETHYLENE GLYCOLS; POLYETHYLENES; RNA, SMALL INTERFERING; TRANSFECTION; TREATMENT OUTCOME; VITAMIN E;

MUS;

EID: 84870666240     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.10.057     Document Type: Article

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