Poly(ε-caprolactone)-Block-poly(Ethyl Ethylene Phosphate) micelles for brain-targeting drug delivery: In vitro and in vivo valuation

Pharmaceutical Research

Volumn 27, Issue 12, 2010, Pages 2657-2669

  Li, Yaping ^a   Zhang, Pengcheng ^a   Hu, Luojuan ^a   Wang, Yucai ^b   Wang, Jun ^b   Feng, Linyin ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

Biodistribution; Blood brain barrier (BBB); Micelle; Polyphosphoester

Indexed keywords

COUMARIN 6; COUMARIN DERIVATIVE; POLY(ETHYLETHYLENE PHOSPHATE); POLYCAPROLACTONE; POLYMER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; CORPUS STRIATUM; DRUG BRAIN LEVEL; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG TARGETING; DRUG TISSUE LEVEL; DRUG UPTAKE; ENCAPSULATION; HIPPOCAMPUS; IN VITRO STUDY; IN VIVO STUDY; INCUBATION TEMPERATURE; INCUBATION TIME; MAXIMUM PLASMA CONCENTRATION; MICELLE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; TIME TO MAXIMUM PLASMA CONCENTRATION;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; COUMARINS; DRUG DELIVERY SYSTEMS; MICE; MICE, INBRED ICR; MICELLES; POLYESTERS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 78651344769     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-010-0265-9     Document Type: Article

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