Bone regeneration using cell-mediated responsive degradable PEG-based scaffolds incorporating with rhBMP-2

Biomaterials

Volumn 34, Issue 5, 2013, Pages 1514-1528

  Yang, Fan ^a,b,c   Wang, Jing ^a,c   Hou, Juan ^c   Guo, Han ^d   Liu, Changsheng ^a,b,c  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b East China University of Science and Technology   (China)

^c East China University of Science and Technology   (China)

^d SHANGHAI INSTITUTE OF APPLIED PHYSICS   (China)

Author keywords

BMP; Bone regeneration; Degradation; Scaffold

Indexed keywords

BIOMECHANICAL MEASUREMENT; BMP; BONE AUGMENTATION; BONE MARROW; BONE REGENERATION; CLINICAL PROBLEMS; CRITICAL DEFECTS; DEGRADATION RATE; DURATION TIME; ECTOPIC BONES; EXTRACELLULAR CONCENTRATION; GROWTH FACTOR; HISTOLOGICAL ANALYSIS; IN-VIVO; MICROCOMPUTED TOMOGRAPHY; MICROENVIRONMENTS; ORTHOPEDIC APPLICATIONS; ORTHOPEDIC SURGERY; OSSEOUS DEFECTS; OSTEOINDUCTION; POLYMER PRECURSORS; RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN-2 (RHBMP-2); REDUCED GLUTATHIONE; RHBMP-2; SELF REPAIRING; TISSUE RECONSTRUCTION; TISSUE REGENERATION; TOMOGRAPHIC;

BIOACTIVITY; BIOMECHANICS; BONE; CELLS; COMPUTERIZED TOMOGRAPHY; CYTOLOGY; DEFECTS; DEGRADATION; ENZYME ACTIVITY; SCAFFOLDS; TISSUE;

SCAFFOLDS (BIOLOGY);

DISULFIDE; GLUTATHIONE; MACROGOL; POLYMER; PROTEINASE; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; TISSUE SCAFFOLD;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIODEGRADABILITY; BIOMECHANICS; BONE DEFECT; BONE MARROW; BONE RADIOGRAPHY; BONE REGENERATION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG EFFECT; ENZYMATIC DEGRADATION; EXPERIMENTAL RABBIT; FIELD EMISSION SCANNING ELECTRON MICROSCOPY; HISTOLOGY; IN VIVO STUDY; LEG MUSCLE; MALE; MICRO-COMPUTED TOMOGRAPHY; MICROENVIRONMENT; MOUSE; NONHUMAN; OSSIFICATION; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN SECRETION; RADIUS; SUSTAINED DRUG RELEASE; SYNCHROTRON RADIATION; SYNTHESIS; THIGH; TISSUE REPAIR;

ABSORBABLE IMPLANTS; ANIMALS; BONE MORPHOGENETIC PROTEIN 2; BONE REGENERATION; DELAYED-ACTION PREPARATIONS; MALE; MICE; POLYETHYLENE GLYCOLS; RABBITS; RADIUS FRACTURES; RECOMBINANT PROTEINS; TISSUE SCAFFOLDS; TRANSFORMING GROWTH FACTOR BETA; TREATMENT OUTCOME;

ORYCTOLAGUS CUNICULUS;

EID: 84870657570     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.10.058     Document Type: Article

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