PEG-based bioresponsive hydrogels with redox-mediated formation and degradation

Journal of Materials Science: Materials in Medicine

Volumn 23, Issue 3, 2012, Pages 697-710

  Yang, Fan ^a   Wang, Jing ^a   Peng, Geng ^a   Fu, Sichao ^a   Zhang, Shuo ^a   Liu, Changsheng ^a  

^a East China University of Science and Technology   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMACROMOLECULES; C2C12 CELLS; CELL VIABILITY; CROSS-LINKED HYDROGELS; DEGRADATION BEHAVIOR; DEGRADATION KINETICS; DEGRADATION PRODUCTS; DEPROTECTION; EXTRACELLULAR LEVELS; GELATION TIME; GLUTATHIONES; GSH CONCENTRATIONS; HIGH CONCENTRATION; MACROSCOPIC TRANSITIONS; PH VALUE; PHYSIOLOGICAL ENVIRONMENT; REDUCTANTS; STIMULI-RESPONSIVE; THIOLATES; TISSUE REGENERATION; TISSUE REPAIR;

COAGULATION; DEGRADATION; ELASTICITY; ENZYME ACTIVITY; GELATION; OXIDANTS; POLYETHYLENE GLYCOLS; TISSUE;

HYDROGELS;

GLUTATHIONE; MACROGOL; MACROGOL DERIVATIVE;

ACCURACY; ARTICLE; CELL VIABILITY; CHEMICAL BOND; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; DEGRADATION; GELATION; HYDROGEL; OXIDATION; PH; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; TEMPERATURE; TISSUE REGENERATION; TISSUE REPAIR; ANIMAL; CELL LINE; CHEMISTRY; FLOW KINETICS; MOUSE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXIDATION REDUCTION REACTION;

ANIMALS; CELL LINE; HYDROGELS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; OXIDATION-REDUCTION; POLYETHYLENE GLYCOLS; RHEOLOGY;

EID: 84862748784     PISSN: 09574530     EISSN: 15734838     Source Type: Journal    
DOI: 10.1007/s10856-012-4555-0     Document Type: Article

References (39)

1. Nguyen MK, Lee DS. Ingectable biodegradable hydrogels. Macromol Biosci. 2010;10:563-79.
2. Hoare TR, Kohane DS. Hydroge Is in drug delivery: progress and challenges. Polymer. 2008;49:1993-2007.
3. Hiemstra C, Van der Aa LJ, Zhong Z, Dijkstra PJ, Feijen J. Rapidly in situ-forming degradable hydroge Is from dextran thio Is through michael addition. Biomacromolecules. 2007;8:1548-56.
4. Ulijn RV, Bibi N, Jayawarna V, Thornto PD, Todd SJ, Mart RJ, et al. Bioresponsive hydrogels. Mater Today. 2007;10:40-8.
5. Langer R, Vacanti JP. Tissue engineering. Science. 1993;260: 920-6.
6. Kraehenbuehl TP, Zammaretti P, Van der Vlies AJ, Schoenmakers RG, Luto If MP, Jaconi ME, et al. Three-dimen-sional extracellular matrix-directed cardioprogenitor differentia-tion: systematic modulation of a synthetic cell-responsive PEG hydrogel. Biomaterials. 2008;29:2757-66.
7. Lutolf MP, Hubbell JA. Synthetic biomateria Is as instructive extracellular microenvironments for morphogenesis in tissue engineering. Nat Biotechnol. 2005;23:47-55.
8. Lei Y, Segura T. DNA delivery from matrix metalloproteinase degradable poly(ethylene glycol) hydroge Is to mouse cloned mesenchymal stem cells. Biomaterials. 2009;30:254-65.
9. Jo YS, Gants J, Hubbell JA, Luto If MP. Tailoring hydrogel degradation and drug release via neighboring amio acid con-trolled ester hydrolysis. Soft Matter. 2009;5:440-6.
10. Lévesque SG, Shoichet MS. Synthesis of enzyme-degradable, peptide-cross-linked dextran hydrogels. Bioconjug Chem. 2007; 18:874-85.
11. Lutolf MP, Raeber GP, Zisch AH, Tire Hi N, Hubbell JA. Cell-responsive synthetic hydrogels. Adv Mater. 2003;15:888-92.
12. Seliktar D, Zisch AH, Lutolf MP, Wrana L, Hubbe He JA. MMP-2 sensitive, VEGF-bearing bioactive hydroge Is for promotion of vascular healing. J Biomed Mater Res. 2004;68A:704-16.
13. Ehrbar M, Rizzi SC, Schoenmakers RG, Miguel BS, Hubbell JA, Weber FE, Lutolf MP. Biomolecular hydroge Is formed and degraded via site-specific enzymatic reactions. Biomacromole-cules. 2007;8:3000-7.
14. Plunkett KN, Berkowski KL, Moore JS. Chymotrypsin respon-sive hydrogel: application of a disulfide exchange protocol for the preparation of methacrylamide containing peptides. Biomacro-molecules. 2005;6:632-7.
15. Thornton PD, Mc Connel1 G, Ulijn RV. Enzyme responsive polymer hydrogel beads. Chem Commun. 2005;47:5913-5.
16. Saito G, Swanson JA, Lee KD. Drug delivery strategy utilizing conjugation via reversible disulfide linkages: role and site of cel-lularreducing activities. Adv Drug Deliv Rev. 2003;55:199-215.
17. Li C, Madsen J, Armes SP, Lewis AL. A new class of bio-chemically degradable, stimulus-responsive triblock copolymer gelators. Angew Chem Int Ed. 2006;45:3510-3.
18. Cline DJ, Redding SE, Brohawn SG, Psathas JN, Schneider JP, Thorpe C. New water-soluble phosphines as reductants ofpeptide and protein disulfide bonds: reactivity and membrane perme-ability. Biochemistry. 2004;43:15195-203.
19. Kurtoglu YE, Navath RS, Wang B, Kannan S, Romero R, Kannan RM. Poly(amidoamine) dendrimer-drag conjugates with disulfide linkages for intracellular drug delivery. Biomaterials. 2009;30: 2112-21.
20. Zalipsky S, Qazen M, Walker JA, Mu Uah N, Quinn YP, Huang SK. New detachable poly(ethylene glycol) conjugates: cysteine-cleavable lipopolymers regenerating natural phospholipid, diacyl phosphatidylethanolamine. Bioconjug Chem. 1999;10:703-7.
21. Zalipskym S, Kiwan R, Qazen M. In: Proceedings of the Inter-national Symposium Control Rel Bioact Mater Controlled Release Society: San Diego; 2001; pp. 437.
22. Meng F, Hennink WE, Zhong Z. Reduction-sensitive polymers and bioconjugates for biomedical applications. Biomaterials. 2009;30:2180-98.
23. Yang J, Jacobsen MT, Pan H, Kopecek J. Synthesis and char-acterization of enzymatically degradable PEG-based peptide-containing hydrogels. Macromol Biosci. 2010;10:445-54.
24. Hiemstra C, Van der Aa LJ, Zhong Z, Dijkstra PJ, Feijen J. Nove1 in situ forming, degradable dextran hydroge Is by michael addi-tion chemistry: synthesis, rheology, and degradation. Macro-molecules. 2007;40:1165-73.
25. EUman GL. A colorimetric method for determining low con-centrations of mercaptans. Arch Biochem Biophys. 1958;74: 443-50.
26. Jin R, Hiemstra C, Zhong Z, Feijen J. Enzyme-mediated fast in situ formation of hydroge Is from dextran-tyramine conjugates. Biomaterials. 2007;28:2791-800.
27. Goessl A, Tire Hi N, Hubbell JA. A hydrogel system for stimulus-responsive, oxygen-sensitive in situ gelation. J Biomater Sci Polym Ed. 2004;15:895-904.
28. Mather BD, Viswanathan K, Miller KM, Long TE. Michael addition reactions in macromolecular design for emerging tech-nologies. Prog Polym Sci. 2006;31:487-53I.
29. Kurisawa M, Chung JE, Yang YY, Gao SJ, Uyama H. Injectable biodegradable tyramine conjugates for drug delivery and tissue engineering. Hydroge Is composed of hyaluronic acid. Chem Commun. 2005;34:4312-4314.
30. Wang LS, Chung JE, Chan PP, Kurisawa M. Injectable biode-gradable hydroge Is with tunable mechanical properties for the stimulation of neurogenic differentiation of human mesenchymal stem ce Us in 3D culture. Biomaterials. 2010;31:1148-57.
31. Kim SH, Won CY, Chu CC. Synthesis and characterization of dextran-based hydrogel prepared by photocrosslinking. Carbo-hydr Polym. 1999;40:183-90.
32. Dennis WH, Rosenblatt DH, Simcox JR. Synthesis of nitrotolu-enesulfonic acids by oxidative cleavage of disulfides. Synthesis. 1974;(4):295-6.
33. Kakizama Y, Harada A, Kataoka K Glutathione-sensitive sta-bilization of block copolymer micelles composed of antisense DNA and thiolated poly(ethylene glycol)-block-poly(L-lysine): a potential carrier for systemic delivery of antisense DNA. Bio-macromolecular. 2001;2:491-7.
34. Kakizama Y, Harada A, Kataoka K. Environment-sensitive sta-bilization of core-shell structured polyion complex micelle by reversible cross-linking of the core through disulfide bond. J Am Chem Soc. 1999;121:11247-8.
35. Wang Y, Chen P, Shen J. The development and characterization of a glutathione-sensitive cross-linked polyethylenimine gene vector. Biomaterials. 2006;27:5292-8.
36. Zhu Y, Tong W, Gao C, Möhwa Id H. Fabrication of bovine seram albumin microcapsules by desolvation and destroyable cross-linking. J Mater Chem. 2008;18:1153-8
37. Bayramoǧlu G, Kayaman-Apohan N, Akcakaya H, Kahraman MV, Kuruca SE, Güngör A. Eeparation of co Uagen modified photopolymers: a new type of biodegradable gel for cell growth. J Mater Sci Mater Med. 2010;21:761-5.
38. Hu C, Zhang L, Wu D, Cheng S, Zhang X, Zhuo R. Heparin-mod-ified PEI encapsulated in thermosensitive hydroge Is for efficient gene delivery and expression. J Mater Chem. 2009;19:3189-97.
39. Bae KH, Mok H, Park TG. Synthesis, characterization, and intracellular delivery of reducible heparin nanoge Is for apoptotic cell death. Biomaterials. 2008;29:3376-83.