Doxycycline loaded poly(ethylene glycol) hydrogels for healing vesicant-induced ocular wounds

Biomaterials

Volumn 31, Issue 5, 2010, Pages 964-974

  Anumolu, SivaNaga S ^a   DeSantis, Andrea S ^a,b   Menjoge, Anupa R ^a   Hahn, Rita A ^a,b   Beloni, John A ^a,b   Gordon, Marion K ^a,b   Sinko, Patrick J ^a  

^a RUTGERS UNIVERSITY   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

Cornea organ culture model; Doxycycline; Hydrogel; Ocular drug delivery; Poly(ethylene glycol); Sustained release

Indexed keywords

CORNEA ORGAN CULTURE MODEL; DOXYCYCLINE; OCULAR DRUG DELIVERY; ORGAN CULTURE; SUSTAINED RELEASE;

CHEMICAL WARFARE; DRUG DELIVERY; ENZYME INHIBITION; ETHYLENE; ETHYLENE GLYCOL; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; SULFUR;

HYDROGELS;

CHLORMETHINE; DOXYCYCLINE; GELATINASE B; MACROGOL; PHOSPHATE BUFFERED SALINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORNEA CELL; CORNEA INJURY; CORNEA OPACITY; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG EFFICACY; DRUG MECHANISM; DRUG PENETRATION; EX VIVO STUDY; EYE SWELLING; FLOW KINETICS; HISTOPATHOLOGY; HYDROGEL; IMMUNOFLUORESCENCE; IN VITRO STUDY; NANOPHARMACEUTICS; NONHUMAN; ORGAN CULTURE; PRIORITY JOURNAL; RABBIT; SUSTAINED DRUG RELEASE; SUSTAINED RELEASE PREPARATION; WOUND HEALING;

ANIMALS; ANTI-BACTERIAL AGENTS; DOXYCYCLINE; DRUG CARRIERS; EYE BURNS; HYDROGELS; IRRITANTS; MATERIALS TESTING; NITROGEN MUSTARD COMPOUNDS; POLYETHYLENE GLYCOLS; RABBITS; TREATMENT OUTCOME; WOUND HEALING;

ORYCTOLAGUS CUNICULUS;

EID: 70649109914     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.10.010     Document Type: Article

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