Critical-size calvarial bone defects healing in a mouse model with silk scaffolds and SATB2-modified iPSCs

Biomaterials

Volumn 32, Issue 22, 2011, Pages 5065-5076

  Ye, Jin Hai ^a,b,c   Xu, Yuan Jin ^a,c   Gao, Jun ^d   Yan, Shi Guo ^a,e   Zhao, Jun ^a,c   Tu, Qisheng ^a   Zhang, Jin ^a,e   Duan, Xue Jing ^a,e   Sommer, Cesar A ^f   Mostoslavsky, Gustavo ^f   Kaplan, David L ^g   Wu, Yu Nong ^b   Zhang, Chen Ping ^c   Wang, Lin ^b   Chen, Jake ^a  

^a TUFTS UNIVERSITY SCHOOL OF DENTAL MEDICINE   (United States)

^b NANJING MEDICAL UNIVERSITY   (China)

^c SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

^d NANJING UNIVERSITY   (China)

^e SHANDONG UNIVERSITY   (China)

^f BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g Tufts University   (United States)

Author keywords

Induced pluripotent stem cells; Osteogenesis; SATB2; Silk scaffold

Indexed keywords

BIOACTIVE SCAFFOLD; BONE FORMATION; BONE SIALOPROTEINS; BONE SUBSTITUTES; CALVARIAL BONES; CALVARIAL DEFECTS; HISTOLOGICAL ANALYSIS; MICRO CT; MOUSE MODELS; MRNA LEVEL; NUCLEAR MATRIX; NUDE MICE; OSTEOCALCIN; OSTEOGENESIS; OSTEOGENIC; OSTEOGENIC DIFFERENTIATION; OSTERIX; OVER-EXPRESSION; PLURIPOTENCY; PLURIPOTENT STEM CELLS; REGENERATION MEDICINE; SATB2; SILK SCAFFOLD;

BIOMATERIALS; BONE; COMPUTERIZED TOMOGRAPHY; DEFECTS; GENES; NUCLEIC ACIDS; RADIOLOGY; SILK; STEM CELLS; TISSUE; TRANSCRIPTION; TRANSCRIPTION FACTORS;

SCAFFOLDS (BIOLOGY);

BONE SIALOPROTEIN; GENE PRODUCT; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GREEN FLUORESCENT PROTEIN; MESSENGER RNA; OCTAMER TRANSCRIPTION FACTOR 4; OSTEOCALCIN; PROTEIN HOXA2; PROTEIN SATB2; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DEFECT; BONE DEVELOPMENT; BONE MINERALIZATION; BONE PROSTHESIS; CALVARIA; CELL DIFFERENTIATION; CELL LINEAGE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; FRACTURE HEALING; MOUSE; NONHUMAN; NUDE MOUSE; OSTEOBLAST; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SILK; STEM CELL TRANSPLANTATION; TISSUE ENGINEERING;

ANIMALS; BIOCOMPATIBLE MATERIALS; BONE REGENERATION; CELL DIFFERENTIATION; CELLS, CULTURED; CORE BINDING FACTOR ALPHA 1 SUBUNIT; HOMEODOMAIN PROTEINS; INDUCED PLURIPOTENT STEM CELLS; INTEGRIN-BINDING SIALOPROTEIN; MATERIALS TESTING; MATRIX ATTACHMENT REGION BINDING PROTEINS; MICE; MICE, NUDE; OSTEOCALCIN; SILK; SKULL; TISSUE ENGINEERING; TISSUE SCAFFOLDS; TRANSCRIPTION FACTORS; TRANSDUCTION, GENETIC; WOUND HEALING;

MUS MUSCULUS;

EID: 79956140280     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.03.053     Document Type: Article

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