Biodegradable composite scaffolds incorporating an intramedullary rod and delivering bone morphogenetic protein-2 for stabilization and bone regeneration in segmental long bone defects

Acta Biomaterialia

Volumn 7, Issue 10, 2011, Pages 3627-3637

  Henslee, A M ^a   Spicer, P P ^a   Yoon, D M ^a   Nair, M B ^a   Meretoja, V V ^a,b   Witherel, K E ^a   Jansen, J A ^c   Mikos, A G ^a   Kasper, F K ^a  

^a Rice University   (United States)

^b UNIVERSITY OF TURKU   (Finland)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Bone morphogenetic protein; Bone regeneration; Bone tissue engineering; Composite scaffold; Intramedullary rod

Indexed keywords

BIOMECHANICS; BONE; COMPUTERIZED TOMOGRAPHY; HISTOLOGY; MICROSPHERES; RECOMBINANT PROTEINS; SCAFFOLDS (BIOLOGY); STABILIZATION; STIFFNESS;

BONE FORMATION; BONE MORPHOGENETIC PROTEIN-2; BONE MORPHOGENETIC PROTEINS; BONE REGENERATION; BONE TISSUE ENGINEERING; COMPOSITE SCAFFOLDS; FUMARATES; HUMAN BONE MORPHOGENETIC PROTEIN; INTRAMEDULLARY RODS; POLY-DL-LACTIC-CO-GLYCOLIC ACIDS;

TISSUE REGENERATION;

POLY(PROPYLENE FUMARATE); POLYGLACTIN; POLYMER; POLYPROPYLENE; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIODEGRADABILITY; BIOMECHANICS; BONE DEFECT; BONE RADIOGRAPHY; BONE REGENERATION; DRUG DOSE COMPARISON; DRUG MEGADOSE; FEMUR; HISTOLOGY; INTRAMEDULLARY NAIL; LOW DRUG DOSE; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; OSSIFICATION; OSTEOSYNTHESIS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; SCANNING ELECTRON MICROSCOPY; SYNTHESIS; TISSUE ENGINEERING; X RAY;

RATTUS;

EID: 80052262096     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2011.06.043     Document Type: Article

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