-
1
-
-
33747830764
-
Hepatocellular carcinoma pathogenesis: from genes to environment
-
Farazi PA, DePinho RA. Hepatocellular carcinoma pathogenesis: from genes to environment. Nature Reviews Cancer 2006; 6: 674-687.
-
(2006)
Nature Reviews Cancer
, vol.6
, pp. 674-687
-
-
Farazi, P.A.1
DePinho, R.A.2
-
2
-
-
0345357773
-
Gene silencing in cancer in association with promoter hypermethylation
-
Herman JG, Baylin SB. Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med 2003; 349: 2042-2054.
-
(2003)
N Engl J Med
, vol.349
, pp. 2042-2054
-
-
Herman, J.G.1
Baylin, S.B.2
-
3
-
-
33847065486
-
The epigenomics of cancer
-
Jones PA, Baylin SB. The epigenomics of cancer. Cell 2007; 128: 683-692.
-
(2007)
Cell
, vol.128
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
4
-
-
81155154239
-
Diagnostic and prognostic molecular markers in hepatocellular carcinoma
-
Minguez B, Lachenmayer A. Diagnostic and prognostic molecular markers in hepatocellular carcinoma. Dis Markers 2011; 31: 181-190.
-
(2011)
Dis Markers
, vol.31
, pp. 181-190
-
-
Minguez, B.1
Lachenmayer, A.2
-
5
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
Clevers H. Wnt/beta-catenin signaling in development and disease. Cell 2006; 127: 469-480.
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
7
-
-
0033895709
-
Wnt signaling and cancer
-
Polakis P. Wnt signaling and cancer. Genes Dev 2000; 14: 1837-1851.
-
(2000)
Genes Dev
, vol.14
, pp. 1837-1851
-
-
Polakis, P.1
-
8
-
-
40949086754
-
Functional interaction between Wnt3 and Frizzled-7 leads to activation of the Wnt/beta-catenin signaling pathway in hepatocellular carcinoma cells
-
Kim M, Lee HC, Tsedensodnom O, Hartley R, Lim YS, Yu E, et al. Functional interaction between Wnt3 and Frizzled-7 leads to activation of the Wnt/beta-catenin signaling pathway in hepatocellular carcinoma cells. J Hepatol 2008; 48: 780-791.
-
(2008)
J Hepatol
, vol.48
, pp. 780-791
-
-
Kim, M.1
Lee, H.C.2
Tsedensodnom, O.3
Hartley, R.4
Lim, Y.S.5
Yu, E.6
-
9
-
-
32844454531
-
Wnt/Frizzled signaling in hepatocellular carcinoma
-
Lee HC, Kim M, Wands JR. Wnt/Frizzled signaling in hepatocellular carcinoma. Front Biosci 2006; 11: 1901-1915.
-
(2006)
Front Biosci
, vol.11
, pp. 1901-1915
-
-
Lee, H.C.1
Kim, M.2
Wands, J.R.3
-
10
-
-
67651174546
-
Promoter methylation and mRNA expression of DKK-3 and WIF-1 in hepatocellular carcinoma
-
Ding Z, Qian YB, Zhu LX, Xiong QR. Promoter methylation and mRNA expression of DKK-3 and WIF-1 in hepatocellular carcinoma. World J Gastroenterol 2009; 15: 2595-2601.
-
(2009)
World J Gastroenterol
, vol.15
, pp. 2595-2601
-
-
Ding, Z.1
Qian, Y.B.2
Zhu, L.X.3
Xiong, Q.R.4
-
11
-
-
33746296615
-
Promoter methylation of the secreted frizzled-related protein 1 gene SFRP1 is frequent in hepatocellular carcinoma
-
Shih YL, Shyu RY, Hsieh CB, Lai HC, Liu KY, Chu TY, et al. Promoter methylation of the secreted frizzled-related protein 1 gene SFRP1 is frequent in hepatocellular carcinoma. Cancer 2006; 107: 579-590.
-
(2006)
Cancer
, vol.107
, pp. 579-590
-
-
Shih, Y.L.1
Shyu, R.Y.2
Hsieh, C.B.3
Lai, H.C.4
Liu, K.Y.5
Chu, T.Y.6
-
12
-
-
0025328296
-
A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes
-
Gubbay J, Collignon J, Koopman P, Capel B, Economou A, Munsterberg A, et al. A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes. Nature 1990; 346: 245-250.
-
(1990)
Nature
, vol.346
, pp. 245-250
-
-
Gubbay, J.1
Collignon, J.2
Koopman, P.3
Capel, B.4
Economou, A.5
Munsterberg, A.6
-
13
-
-
70449346711
-
The Yin and Yang of Sox proteins: activation and repression in development and disease
-
Chew LJ, Gallo V. The Yin and Yang of Sox proteins: activation and repression in development and disease. J Neurosci Res 2009; 87: 3277-3287.
-
(2009)
J Neurosci Res
, vol.87
, pp. 3277-3287
-
-
Chew, L.J.1
Gallo, V.2
-
14
-
-
39449092456
-
SOX2 is frequently downregulated in gastric cancers and inhibits cell growth through cell-cycle arrest and apoptosis
-
Otsubo T, Akiyama Y, Yanagihara K, Yuasa Y. SOX2 is frequently downregulated in gastric cancers and inhibits cell growth through cell-cycle arrest and apoptosis. Br J Cancer 2008; 98: 824-831.
-
(2008)
Br J Cancer
, vol.98
, pp. 824-831
-
-
Otsubo, T.1
Akiyama, Y.2
Yanagihara, K.3
Yuasa, Y.4
-
15
-
-
53349141350
-
Sox7 is an independent checkpoint for beta-catenin function in prostate and colon epithelial cells
-
Guo L, Zhong D, Lau S, Liu X, Dong XY, Sun X, et al. Sox7 is an independent checkpoint for beta-catenin function in prostate and colon epithelial cells. Mol Cancer Res 2008; 6: 1421-1430.
-
(2008)
Mol Cancer Res
, vol.6
, pp. 1421-1430
-
-
Guo, L.1
Zhong, D.2
Lau, S.3
Liu, X.4
Dong, X.Y.5
Sun, X.6
-
16
-
-
38549123030
-
Identification of DNA hypermethylation of SOX9 in association with bladder cancer progression using CpG microarrays
-
Aleman A, Adrien L, Lopez-Serra L, Cordon-Cardo C, Esteller M, Belbin TJ, et al. Identification of DNA hypermethylation of SOX9 in association with bladder cancer progression using CpG microarrays. Br J Cancer 2008; 98: 466-473.
-
(2008)
Br J Cancer
, vol.98
, pp. 466-473
-
-
Aleman, A.1
Adrien, L.2
Lopez-Serra, L.3
Cordon-Cardo, C.4
Esteller, M.5
Belbin, T.J.6
-
17
-
-
78449244507
-
SOX17 antagonizes WNT/beta-catenin signaling pathway in hepatocellular carcinoma
-
Jia Y, Yang Y, Liu S, Herman JG, Lu F, Guo M. SOX17 antagonizes WNT/beta-catenin signaling pathway in hepatocellular carcinoma. Epigenetics 2010; 5: 743-749.
-
(2010)
Epigenetics
, vol.5
, pp. 743-749
-
-
Jia, Y.1
Yang, Y.2
Liu, S.3
Herman, J.G.4
Lu, F.5
Guo, M.6
-
18
-
-
77957341495
-
Epigenetic regulation of CpG promoter methylation in invasive prostate cancer cells
-
Mathews LA, Hurt EM, Zhang X, Farrar WL. Epigenetic regulation of CpG promoter methylation in invasive prostate cancer cells. Mol Cancer 2010; 9: 267.
-
(2010)
Mol Cancer
, vol.9
, pp. 267
-
-
Mathews, L.A.1
Hurt, E.M.2
Zhang, X.3
Farrar, W.L.4
-
19
-
-
80055106066
-
Genetic and epigenetic modifications of Sox2 contribute to the invasive phenotype of malignant gliomas
-
Alonso MM, Diez-Valle R, Manterola L, Rubio A, Liu D, Cortes-Santiago N, et al. Genetic and epigenetic modifications of Sox2 contribute to the invasive phenotype of malignant gliomas. PLoS One 2011; 6: e26740.
-
(2011)
PLoS One
, vol.6
-
-
Alonso, M.M.1
Diez-Valle, R.2
Manterola, L.3
Rubio, A.4
Liu, D.5
Cortes-Santiago, N.6
-
20
-
-
0033676762
-
The oncogenic potential of the high mobility group box protein Sox3
-
Xia Y, Papalopulu N, Vogt PK, Li J. The oncogenic potential of the high mobility group box protein Sox3. Cancer Res 2000; 60: 6303-6306.
-
(2000)
Cancer Res
, vol.60
, pp. 6303-6306
-
-
Xia, Y.1
Papalopulu, N.2
Vogt, P.K.3
Li, J.4
-
21
-
-
84857700780
-
Oncogenicity of the developmental transcription factor Sox9
-
Matheu A, Collado M, Wise C, Manterola L, Cekaite L, Tye AJ, et al. Oncogenicity of the developmental transcription factor Sox9. Cancer Res 2012; 72: 1301-1315.
-
(2012)
Cancer Res
, vol.72
, pp. 1301-1315
-
-
Matheu, A.1
Collado, M.2
Wise, C.3
Manterola, L.4
Cekaite, L.5
Tye, A.J.6
-
22
-
-
2442514340
-
Interactions between Sox9 and beta-catenin control chondrocyte differentiation
-
Akiyama H, Lyons JP, Mori-Akiyama Y, Yang X, Zhang R, Zhang Z, et al. Interactions between Sox9 and beta-catenin control chondrocyte differentiation. Genes Dev 2004; 18: 1072-1087.
-
(2004)
Genes Dev
, vol.18
, pp. 1072-1087
-
-
Akiyama, H.1
Lyons, J.P.2
Mori-Akiyama, Y.3
Yang, X.4
Zhang, R.5
Zhang, Z.6
-
23
-
-
36048993973
-
Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells
-
Sinner D, Kordich JJ, Spence JR, Opoka R, Rankin S, Lin SCJ, et al. Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells. Mol Cell Biol 2007; 27: 7802-7815.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 7802-7815
-
-
Sinner, D.1
Kordich, J.J.2
Spence, J.R.3
Opoka, R.4
Rankin, S.5
Lin, S.C.J.6
-
24
-
-
0036696817
-
Twenty pairs of sox: extent, homology, and nomenclature of the mouse and human sox transcription factor gene families
-
Schepers GE, Teasdale RD, Koopman P. Twenty pairs of sox: extent, homology, and nomenclature of the mouse and human sox transcription factor gene families. Dev Cell 2002; 3: 167-170.
-
(2002)
Dev Cell
, vol.3
, pp. 167-170
-
-
Schepers, G.E.1
Teasdale, R.D.2
Koopman, P.3
-
25
-
-
0036744745
-
Formation of neuroblasts in the embryonic central nervous system of Drosophila melanogaster is controlled by SoxNeuro
-
Buescher M, Hing FS, Chia W. Formation of neuroblasts in the embryonic central nervous system of Drosophila melanogaster is controlled by SoxNeuro. Development 2002; 129: 4193-4203.
-
(2002)
Development
, vol.129
, pp. 4193-4203
-
-
Buescher, M.1
Hing, F.S.2
Chia, W.3
-
26
-
-
1942521309
-
Sox1 acts through multiple independent pathways to promote neurogenesis
-
Kan L, Israsena N, Zhang Z, Hu M, Zhao L-R, Jalali A, et al. Sox1 acts through multiple independent pathways to promote neurogenesis. Dev Biol 2004; 269: 580-594.
-
(2004)
Dev Biol
, vol.269
, pp. 580-594
-
-
Kan, L.1
Israsena, N.2
Zhang, Z.3
Hu, M.4
Zhao, L.-R.5
Jalali, A.6
-
27
-
-
43949142803
-
Identification of novel DNA methylation markers in cervical cancer
-
Lai HC, Lin YW, Huang TH, Yan P, Huang RL, Wang HC, et al. Identification of novel DNA methylation markers in cervical cancer. Int J Cancer 2008; 123: 161-167.
-
(2008)
Int J Cancer
, vol.123
, pp. 161-167
-
-
Lai, H.C.1
Lin, Y.W.2
Huang, T.H.3
Yan, P.4
Huang, R.L.5
Wang, H.C.6
-
28
-
-
58249087346
-
An epigenetic marker panel for screening and prognostic prediction of ovarian cancer
-
Su HY, Lai HC, Lin YW, Chou YC, Liu CY, Yu MH. An epigenetic marker panel for screening and prognostic prediction of ovarian cancer. Int J Cancer 2009; 124: 387-393.
-
(2009)
Int J Cancer
, vol.124
, pp. 387-393
-
-
Su, H.Y.1
Lai, H.C.2
Lin, Y.W.3
Chou, Y.C.4
Liu, C.Y.5
Yu, M.H.6
-
29
-
-
34547093863
-
SFRP1 suppressed hepatoma cells growth through Wnt canonical signaling pathway
-
Shih YL, Hsieh CB, Lai HC, Yan MD, Hsieh TY, Chao YC, et al. SFRP1 suppressed hepatoma cells growth through Wnt canonical signaling pathway. Int J Cancer 2007; 121: 1028-1035.
-
(2007)
Int J Cancer
, vol.121
, pp. 1028-1035
-
-
Shih, Y.L.1
Hsieh, C.B.2
Lai, H.C.3
Yan, M.D.4
Hsieh, T.Y.5
Chao, Y.C.6
-
30
-
-
77957339798
-
Quantitative DNA methylation analysis detects cervical intraepithelial neoplasms type 3 and worse
-
Lai HC, Lin YW, Huang RL, Chung MT, Wang HC, Liao YP, et al. Quantitative DNA methylation analysis detects cervical intraepithelial neoplasms type 3 and worse. Cancer 2010; 116: 4266-4274.
-
(2010)
Cancer
, vol.116
, pp. 4266-4274
-
-
Lai, H.C.1
Lin, Y.W.2
Huang, R.L.3
Chung, M.T.4
Wang, H.C.5
Liao, Y.P.6
-
31
-
-
27544496133
-
Expression of Frzb/secreted Frizzled-related protein 3, a secreted Wnt antagonist, in human androgen-independent prostate cancer PC-3 cells suppresses tumor growth and cellular invasiveness
-
Zi X, Guo Y, Simoneau AR, Hope C, Xie J, Holcombe RF, et al. Expression of Frzb/secreted Frizzled-related protein 3, a secreted Wnt antagonist, in human androgen-independent prostate cancer PC-3 cells suppresses tumor growth and cellular invasiveness. Cancer Res 2005; 65: 9762-9770.
-
(2005)
Cancer Res
, vol.65
, pp. 9762-9770
-
-
Zi, X.1
Guo, Y.2
Simoneau, A.R.3
Hope, C.4
Xie, J.5
Holcombe, R.F.6
-
32
-
-
12144291274
-
Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer
-
Suzuki H, Watkins DN, Jair KW, Schuebel KE, Markowitz SD, Chen WD, et al. Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer. Nat Genet 2004; 36: 417-422.
-
(2004)
Nat Genet
, vol.36
, pp. 417-422
-
-
Suzuki, H.1
Watkins, D.N.2
Jair, K.W.3
Schuebel, K.E.4
Markowitz, S.D.5
Chen, W.D.6
-
33
-
-
73949105534
-
Interactions between SOX factors and Wnt/beta-catenin signaling in development and disease
-
Kormish JD, Sinner D, Zorn AM. Interactions between SOX factors and Wnt/beta-catenin signaling in development and disease. Dev Dyn 2010; 239: 56-68.
-
(2010)
Dev Dyn
, vol.239
, pp. 56-68
-
-
Kormish, J.D.1
Sinner, D.2
Zorn, A.M.3
-
34
-
-
0033213619
-
Regulation of Wnt signaling by Sox proteins: XSox17 alpha/beta and XSox3 physically interact with beta-catenin
-
Zorn AM, Barish GD, Williams BO, Lavender P, Klymkowsky MW, Varmus HE. Regulation of Wnt signaling by Sox proteins: XSox17 alpha/beta and XSox3 physically interact with beta-catenin. Mol Cell 1999; 4: 487-498.
-
(1999)
Mol Cell
, vol.4
, pp. 487-498
-
-
Zorn, A.M.1
Barish, G.D.2
Williams, B.O.3
Lavender, P.4
Klymkowsky, M.W.5
Varmus, H.E.6
-
35
-
-
42349108108
-
Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer
-
Zhang W, Glockner SC, Guo M, Machida EO, Wang DH, Easwaran H, et al. Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer. Cancer Res 2008; 68: 2764-2772.
-
(2008)
Cancer Res
, vol.68
, pp. 2764-2772
-
-
Zhang, W.1
Glockner, S.C.2
Guo, M.3
Machida, E.O.4
Wang, D.H.5
Easwaran, H.6
-
36
-
-
16844363879
-
Sox2 induction by FGF and FGFR2 activating mutations inhibits Wnt signaling and osteoblast differentiation
-
Mansukhani A. Sox2 induction by FGF and FGFR2 activating mutations inhibits Wnt signaling and osteoblast differentiation. J Cell Biol 2005; 168: 1065-1076.
-
(2005)
J Cell Biol
, vol.168
, pp. 1065-1076
-
-
Mansukhani, A.1
-
37
-
-
0034175998
-
Pairing SOX off: with partners in the regulation of embryonic development
-
Kamachi Y, Uchikawa M, Kondoh H. Pairing SOX off: with partners in the regulation of embryonic development. Trends Genet 2000; 16: 182-187.
-
(2000)
Trends Genet
, vol.16
, pp. 182-187
-
-
Kamachi, Y.1
Uchikawa, M.2
Kondoh, H.3
-
38
-
-
76549093805
-
SOX-partner code for cell specification: regulatory target selection and underlying molecular mechanisms
-
Kondoh H, Kamachi Y. SOX-partner code for cell specification: regulatory target selection and underlying molecular mechanisms. Int J Biochem Cell Biol 2010; 42: 391-399.
-
(2010)
Int J Biochem Cell Biol
, vol.42
, pp. 391-399
-
-
Kondoh, H.1
Kamachi, Y.2
-
40
-
-
0035836706
-
Myc represses the p21(WAF1/CIP1) promoter and interacts with Sp1/Sp3
-
Gartel AL, Ye X, Goufman E, Shianov P, Hay N, Najmabadi F, et al. Myc represses the p21(WAF1/CIP1) promoter and interacts with Sp1/Sp3. Proc Natl Acad Sci U S A 2001; 98: 4510-4515.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 4510-4515
-
-
Gartel, A.L.1
Ye, X.2
Goufman, E.3
Shianov, P.4
Hay, N.5
Najmabadi, F.6
-
41
-
-
18644373146
-
The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
-
van de Wetering M, Sancho E, Verweij C, de Lau W, Oving I, Hurlstone A, et al. The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell 2002; 111: 241-250.
-
(2002)
Cell
, vol.111
, pp. 241-250
-
-
van de Wetering, M.1
Sancho, E.2
Verweij, C.3
de Lau, W.4
Oving, I.5
Hurlstone, A.6
-
42
-
-
34547129844
-
SOX6 suppresses cyclin D1 promoter activity by interacting with beta-catenin and histone deacetylase 1, and its down-regulation induces pancreatic beta-cell proliferation
-
Iguchi H, Urashima Y, Inagaki Y, Ikeda Y, Okamura M, Tanaka T, et al. SOX6 suppresses cyclin D1 promoter activity by interacting with beta-catenin and histone deacetylase 1, and its down-regulation induces pancreatic beta-cell proliferation. J Biol Chem 2007; 282: 19052-19061.
-
(2007)
J Biol Chem
, vol.282
, pp. 19052-19061
-
-
Iguchi, H.1
Urashima, Y.2
Inagaki, Y.3
Ikeda, Y.4
Okamura, M.5
Tanaka, T.6
-
43
-
-
34447543913
-
Cellular senescence in cancer and aging
-
Collado M, Blasco MA, Serrano M. Cellular senescence in cancer and aging. Cell 2007; 130: 223-233.
-
(2007)
Cell
, vol.130
, pp. 223-233
-
-
Collado, M.1
Blasco, M.A.2
Serrano, M.3
-
44
-
-
0034028836
-
Tumor suppressors and oncogenes in cellular senescence
-
Bringold F, Serrano M. Tumor suppressors and oncogenes in cellular senescence. Exp Gerontol 2000; 35: 317-329.
-
(2000)
Exp Gerontol
, vol.35
, pp. 317-329
-
-
Bringold, F.1
Serrano, M.2
-
45
-
-
34447343780
-
Downregulation of Wnt signaling is a trigger for formation of facultative heterochromatin and onset of cell senescence in primary human cells
-
Ye X, Zerlanko B, Kennedy A, Banumathy G, Zhang R, Adams PD. Downregulation of Wnt signaling is a trigger for formation of facultative heterochromatin and onset of cell senescence in primary human cells. Mol Cell 2007; 27: 183-196.
-
(2007)
Mol Cell
, vol.27
, pp. 183-196
-
-
Ye, X.1
Zerlanko, B.2
Kennedy, A.3
Banumathy, G.4
Zhang, R.5
Adams, P.D.6
-
46
-
-
33644871338
-
Reduced c-Myc signaling triggers telomere-independent senescence by regulating Bmi-1 and p16(INK4a)
-
Guney I, Wu S, Sedivy JM. Reduced c-Myc signaling triggers telomere-independent senescence by regulating Bmi-1 and p16(INK4a). Proc Natl Acad Sci U S A 2006; 103: 3645-3650.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 3645-3650
-
-
Guney, I.1
Wu, S.2
Sedivy, J.M.3
-
47
-
-
84857141264
-
BAG2 is a target of the c-Myc gene and is involved in cellular senescence via the p21(CIP1) pathway
-
Zhang J, Lou X, Yang S, He S, Yang L, Liu M, et al. BAG2 is a target of the c-Myc gene and is involved in cellular senescence via the p21(CIP1) pathway. Cancer Lett 2012; 318: 34-41.
-
(2012)
Cancer Lett
, vol.318
, pp. 34-41
-
-
Zhang, J.1
Lou, X.2
Yang, S.3
He, S.4
Yang, L.5
Liu, M.6
|