Decrease of microRNA-122 causes hepatic insulin resistance by inducing protein tyrosine phosphatase 1B, which is reversed by licorice flavonoid

Hepatology

Volumn 56, Issue 6, 2012, Pages 2209-2220

  Yang, Yoon Mee ^a   Seo, So Yeon ^a   Kim, Tae Hyun ^a   Kim, Sang Geon ^a  

^a Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; ISOLIQUIRITIGENIN; LIQUIRITIGENIN; MESSENGER RNA; MICRORNA 122; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN TYROSINE PHOSPHATASE 1B; STRESS ACTIVATED PROTEIN KINASE 1; TUMOR NECROSIS FACTOR ALPHA;

3' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; DOWN REGULATION; ENZYME PHOSPHORYLATION; GLYCYRRHIZA; INSULIN RESISTANCE; LIPID DIET; LIVER; LIVER CELL; NONHUMAN; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

3' UNTRANSLATED REGIONS; 3T3-L1 CELLS; ANIMALS; CHALCONES; DIET, HIGH-FAT; DOWN-REGULATION; FLAVANONES; HEP G2 CELLS; HEPATOCYTE NUCLEAR FACTOR 4; HEPATOCYTES; HUMANS; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MICE; MICE, INBRED C57BL; MICRORNAS; MITOGEN-ACTIVATED PROTEIN KINASE 8; PHOSPHORYLATION; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 84870541856     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.25912     Document Type: Article

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