Effect of cellular senescence on the albumin permeability of blood-derived endothelial cells

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 303, Issue 11, 2012, Pages

  Cheung, Tracy M ^a   Ganatra, Mansi P ^a   Peters, Erica B ^a   Truskey, George A ^a  

^a Duke University   (United States)

Author keywords

Cell aging; Endothelial progenitor cell; Occludin; Permeability; Vascular biology

Indexed keywords

ALBUMIN; CYCLIC AMP; OCCLUDIN; PROTEIN ZO2; RESVERATROL; TYROSINE;

ARTICLE; CELL AGING; CELL MEMBRANE PERMEABILITY; CELL PROLIFERATION; HUMAN; HUMAN CELL; MITOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; UMBILICAL VEIN ENDOTHELIAL CELL;

ALBUMINS; AORTA; CELL AGING; CELL MEMBRANE PERMEABILITY; CELL PROLIFERATION; CELLS, CULTURED; CYCLIC AMP; ENDOTHELIUM, VASCULAR; FETAL BLOOD; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; OCCLUDIN; PHOSPHORYLATION; SIGNAL TRANSDUCTION; SIRTUIN 1; STILBENES; TIGHT JUNCTION PROTEINS;

EID: 84870511292     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00182.2012     Document Type: Article

References (53)

1. Ahmann KA, Johnson SL, Hebbel RP, Tranquillo RT. Shear stress responses of adult blood outgrowth endothelial cells seeded on bioartifical tissue. Tissue Eng 17: 2511-2521, 2011.
2. Albelda SM, Sampson PM, Haselton FR, McNiff JM, Mueller SN, Williams SK, Fishman AP, Levine EM. Permeability characteristics of cultured endothelial cell monolayers. J Appl Physiol 64: 308-322, 1988.
3. Balda MS, Gonzalez-Mariscal L, Matter K, Cereijido M, Anderson JM. Assembly of the tight junction: the role of diacylglycerol. J Cell Biol 123: 293-302, 1993.
4. Beatch M, Jesaitis LA, Gallin WJ, Goodenough DA, Stevenson BR. The tight junction protein ZO-2 contains three PDZ (PSD-95/discs-large/ ZO-1) domains and an alternatively spliced region. J Biol Chem 271: 25723-25726, 1996.
5. 131I-albumin in the young pig. Exp Mol Pathol 20: 57-68, 1974.
6. Bratzler R, Chisolm G, Colton C, Smith K, Zilversmit D, Lees R. The distribution of labeled albumin across the rabbit thoracic aorta in vivo. Circ Res 40: 182-190, 1977.
7. Brown MA, Wallace CS, Angelos M, Truskey GA. Characterization of umbilical cord blood-derived late outgrowth endothelial progenitor cells exposed to laminar shear stress. Tissue Eng 15: 3575-3587, 2009.
8. Brown MA, Zhang L, Levering VW, Wu JH, Satterwhite LL, Brian L, Freedman NJ, Truskey GA. Human umbilical cord blood-derived endothelial cells reendothelialize vein grafts and prevent thrombosis. Arterioscler Thromb Vasc Biol 30: 2150-2155, 2010.
9. Burrig K. The endothelium of advanced arteriosclerotic plaques in humans. Arterioscler Thromb Vasc Biol 11: 1678-1689, 1991.
10. Campisi J. Replicative senescence: an old lives' tale? Cell 84: 497-500, 1996.
11. Cancel LM, Fitting A, Tarbell JM. In vitro study of LDL transport under pressurized (convective) conditions. Am J Physiol Heart Circ Physiol 293: H126-H132, 2007.
12. Cancel LM, Tarbell JM. The role of apoptosis in LDL transport through cultured endothelial cell monolayers. Atherosclerosis 208: 335-341, 2010.
13. Cao L, Wu A, Truskey GA. Biomechanical effects of flow and coculture on human aortic and cord blood-derived endothelial cells. J Biomech 44: 2150-2157, 2011.
14. Chang YS, Munn LL, Hillsley MV, Dull RO, Yuan J, Lakshminarayanan S, Gardner TW, Jain RK, Tarbell JM. Effect of vascular endothelial growth factor on cultured endothelial cell monolayer rransport properties. Microvasc Res 59: 265-277, 2000.
15. Chen Z, Peng IC, Cuia X, Li YS, Chien S, Shyy JYJ. Shear stress, SIRT1, and vascular homeostasis. Proc Natl Acad Sci USA 107: 10268-10273, 2010.
16. Colgan OC, Ferguson G, Collins NT, Murphy RP, Meade G, Cahill PA, Cummins PM. Regulation of bovine brain microvascular endothelial tight junction assembly and barrier function by laminar shear stress. Am J Physiol Heart Circ Physiol 292: H3190-H3197, 2007.
17. Collins NT, Cummins PM, Colgan OC, Ferguson G, Birney YA, Murphy RP, Meade G, Cahill PA. Cyclic strain-mediated regulation of vascular endothelial occludin and ZO-1. Arterioscler Thromb Vasc Biol 26: 62-68, 2006.
18. Csiszar A, Labinskyy N, Pinto JT, Ballabh P, Zhang H, Losonczy G, Pearson K, de Cabo R, Pacher P, Zhang C, Ungvari Z. Resveratrol induces mitochondrial biogenesis in endothelial cells. Am J Physiol Heart Circ Physiol 297: H13-H20, 2009.
19. Cullere X, Shaw SK, Andersson L, Hirahashi J, Luscinskas FW, Mayadas TN. Regulation of vascular endothelial barrier function by Epac, a cAMP-activated exchange factor for Rap GTPase. Blood 105: 1950-1955, 2005.
20. DeMaio L, Chang YS, Gardner TW, Tarbell JM, Antonetti DA. Shear stress regulates occludin content and phosphorylation. Am J Physiol Heart Circ Physiol 281: H105-H113, 2001.
21. Elias BC, Suzuki T, Seth A, Giorgianni F, Kale G, Shen L, Turner JR, Naren A, Desiderio DM, Rao R. Phosphorylation of Tyr-398 and Tyr-402 in occludin prevents its interaction with ZO-1 and destabilizes its assembly at the tight junctions. J Biol Chem 284: 1559-1569, 2009.
22. Erusalimsky JD, Skene C. Mechanisms of endothelial senescence. Exp Physiol 94: 299-304, 2009.
23. Farrall AJ, Wardlaw JM. Blood-brain barrier: ageing and microvascular disease-systematic review and meta-analysis. Neurobiol Aging 30: 337-352, 2009.
24. Fukuhara S, Sakurai A, Sano H, Yamagishi A, Somekawa S, Takakura N, Saito Y, Kangawa K, Mochizuki N. Cyclic AMP potentiates vascular endothelial cadherin-mediated cell-cell contact to enhance endothelial barrier function through an Epac-Rap1 signaling pathway. Mol Cell Biol 25: 136-146, 2005.
25. Gu J, Wang C, Fan H, Ding H, Xie X, Xu Y, Wang B, Huang D. Effects of resveratrol on endothelial progenitor cells and their contributions to reendothelialization in intima-injured rats. J Cardiovasc Pharmacol 47: 711-721, 2006.
26. Hagensen MK, Shim J, Thim T, Falk E, Bentzon JF. Circulating endothelial progenitor cells do not contribute to plaque endothelium in murine atherosclerosis. Circulation 121: 898-905, 2010.
27. Herrmann RA, Malinauskas RA, Truskey GA. Characterization of sites of elevated low density lipoprotein at the intercostal, celiac, and iliac branches of the rabbit aorta. Arterioscler Thromb 14: 313-323, 1994.
28. Hirschi KK, Ingram DA, Yoder MC. Assessing identity, phenotype, and fate of endothelial progenitor cells. Arterioscler Thromb Vasc Biol 28: 1584-1595, 2008.
29. Ingram DA, Mead LE, Moore DB, Woodard W, Fenoglio A, Yoder MC. Vessel wall-derived endothelial cells rapidly proliferate because they contain a complete hierarchy of endothelial progenitor cells. Blood 105: 2783-2786, 2005.
30. Ingram DA, Mead LE, Tanaka H, Meade V, Fenoglio A, Mortell K, Pollok K, Ferkowicz MJ, Gilley D, Yoder MC. Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood. Blood 104: 2752-2760, 2004.
31. Jickling G, Salam A, Mohammad A, Hussain MS, Scozzafava J, Nasser AM, Jeerakathil T, Shuaib A, Camicioli R. Circulating endothelial progenitor cells and age-related white matter changes. Stroke 40: 3191-3196, 2009.
32. Lin SJ, Jan KM, Schuessler G, Weinbaum S, Chien S. Enhanced macromolecular permeability of aortic endothelial cells in association with mitosis. Atherosclerosis 73: 223-232, 1988.
33. Mammone T, Gan D, Foyouzi-Youssefi R. Apoptotic cell death increases with senescence in normal human dermal fibroblast cultures. Cell Biol Int 30: 903-909, 2006.
34. Mehta D, Malik AB. Signaling mechanisms regulating endothelial permeability. Physiol Rev 86: 279-367, 2006.
35. Meyer G, Merval R, Tedgui A. Effects of pressure-induced stretch and convection on low-density lipoprotein and albumin uptake in the rabbit aortic wall. Circ Res 79: 532-540, 1996.
36. Minamino T, Miyauchi H, Yoshida T, Ishida Y, Yoshida H, Komuro I. Endothelial cell senescence in human atherosclerosis. Circulation 105: 1541-1544, 2002.
37. Murakami T, Felinski EA, Antonetti DA. Occludin phosphorylation and ubiquitination regulate tight junction trafficking and vascular endothelial growth factor-induced permeability. J Biol Chem 284: 21036-21046, 2009.
38. Nielsen LB, Nordestgaard BG, Stender S, Kjeldsen K. Aortic permeability to LDL as a predictor of aortic cholesterol accumulation in cholesterol-fed rabbits. Arterioscler Thromb Vasc Biol 12: 1402-1409, 1992.
39. Ogami M, Ikura Y, Ohsawa M, Matsuo T, Kayo S, Yoshimi N, Hai E, Shirai N, Ehara S, Komatsu R, Naruko T, Ueda M. Telomere shortening in human coronary artery diseases. Arterioscler Thromb Vasc Biol 24: 546-550, 2004.
40. Park SJ, Ahmad F, Philp A, Baar K, Williams T, Luo H, Ke H, Rehmann H, Taussig R, Brown Alexandra L, Kim Myung K, Beaven Michael A, Burgin Alex B, Manganiello V, Chung JH. Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting camp phosphodiesterases. Cell 148: 421-433, 2012.
41. Rampersad SN, Ovens JD, Huston E, Umana MB, Wilson LS, Netherton SJ, Lynch MJ, Baillie GS, Houslay MD, Maurice DH. Cyclic AMP phosphodiesterase 4D (PDE4D) Tethers EPAC1 in a vascular endothelial cadherin (VE-Cad)-based signaling complex and controls cAMP-mediated vascular permeability. J Biol Chem 285: 33614-33622, 2010.
42. Rauscher FM, Goldschmidt-Clermont PJ, Davis BH, Wang T, Gregg D, Ramaswami P, Pippen AM, Annex BH, Dong C, Taylor DA. Aging, progenitor cell exhaustion, and atherosclerosis. Circulation 108: 457-463, 2003.
43. Tarbell JM. Shear stress and the endothelial transport barrier. Cardiovasc Res 87: 320-330, 2010.
44. Topakian R, Barrick TR, Howe FA, Markus HS. Blood-brain barrier permeability is increased in normal-appearing white matter in patients with lacunar stroke and leucoaraiosis. J Neurol Neurosurg Psychiatry 81: 192-197, 2010.
45. Ungvari Z, Bagi Z, Feher A, Recchia FA, Sonntag WE, Pearson K, de Cabo R, Csiszar A. Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2. Am J Physiol Heart Circ Physiol 299: H18-H24, 2010.
46. van der Loo B, Fenton MJ, Erusalimsky JD. Cytochemical detection of a senescence-associated β-galactosidase in endothelial and smooth muscle cells from human and rabbit blood vessels. Exp Cell Res 241: 309-315, 1998.
47. Wachtel M, Frei K, Ehler E, Fontana A, Winterhalter K, Gloor SM. Occludin proteolysis and increased permeability in endothelial cells through tyrosine phosphatase inhibition. J Cell Sci 112: 4347-4356, 1999.
48. Wallace CS, Champion JC, Truskey GA. Adhesion and function of human endothelial cells co-cultured on smooth muscle cells. Ann Biomed Eng 35: 375-386, 2007.
49. Walsh TG, Murphy RP, Fitzpatrick P, Rochfort KD, Guinan AF, Murphy A, Cummins PM. Stabilization of brain microvascular endothelial barrier function by shear stress involves VE-cadherin signaling leading to modulation of pTyr-occludin levels. J Cell Physiol 226: 3053-3063, 2011.
50. Xia L, Wang XX, Hu XS, Guo XG, Shang YP, Chen HJ, Zeng CL, Zhang FR, Chen JZ. Resveratrol reduces endothelial progenitor cells senescence through augmentation of telomerase activity by Akt-dependent mechanisms. Br J Pharmacol 155: 387-394, 2008.
51. Xu Q, Zhang Z, Davison F, Hu Y. Circulating progenitor cells regenerate endothelium of vein graft atherosclerosis, which is diminished in ApoEdeficient mice. Circ Res 93: e76-e86, 2003.
52. Zhang L, Freedman NJ, Brian L, Peppel K. Graft-extrinsic cells predominate in vein graft arterialization. Arterioscler Thromb Vasc Biol 24: 470-476, 2004.
53. Zu Y, Liu L, Lee MYK, Xu C, Liang Y, Man RY, Vanhoutte PM, Wang Y. SIRT1 promotes proliferation and prevents senescence through targeting LKB1 in primary porcine aortic endothelial cells. Circ Res 106: 1384-1393, 2010.