Characterization of umbilical cord blood-derived late outgrowth endothelial progenitor cells exposed to laminar shear stress

Tissue Engineering - Part A

Volumn 15, Issue 11, 2009, Pages 3575-3587

  Brown, Melissa A ^a   Wallace, Charles S ^a   Angelos, Mathew ^a   Truskey, George A ^a  

^a Duke University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESION; BLOOD; BLOOD VESSEL PROSTHESES; BLOOD VESSELS; CELL ADHESION; ELECTRIC CIRCUIT BREAKERS; GLYCOPROTEINS; GRAFTS; MUSCLE; NITRIC OXIDE; PROTEINS; SELF ASSEMBLY; SHEAR STRESS; STRENGTH OF MATERIALS;

ANTITHROMBOTIC; CELL SOURCES; CELL TYPES; COATED GLASS; COCULTURE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIAL PROGENITOR CELLS; FLOW CONDITION; FUNCTIONAL BEHAVIORS; HUMAN AORTIC ENDOTHELIAL CELLS; INTEGRINS; LAMINAR SHEAR STRESS; MRNA LEVEL; PROLIFERATION RATE; PROTEIN LEVEL; SELECTINS; SIMILAR NUMBERS; SMOOTH MUSCLE CELLS; SYNTHETIC VASCULAR GRAFT; TISSUE-ENGINEERED BLOOD VESSELS; TUMOR NECROSIS FACTORS; UMBILICAL CORD BLOOD; VASCULAR CELL ADHESION MOLECULE-1;

ENDOTHELIAL CELLS;

CD14 ANTIGEN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FIBRONECTIN; L SELECTIN; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1; VERY LATE ACTIVATION ANTIGEN 5; VITRONECTIN RECEPTOR;

ARTICLE; CELL ADHESION; CELL CULTURE; CELL FUNCTION; CELL GROWTH; CELL PROLIFERATION; CELL SPREADING; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHEAR STRESS; STEM CELL; TISSUE ENGINEERING; UMBILICAL CORD BLOOD;

EID: 72649088994     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2008.0444     Document Type: Article

References (54)

1. Shirota, T., He, H., Yasui, H., and Matsuda, T. Human en-dothelial progenitor cell-seeded hybrid graft: proliferative and antithrombogenic potentials in vitro and fabrication processing. Tissue Eng 9, 127, 2003.
2. Gong, Z., and Niklason, L.E. Blood vessels engineered from human cells. Trends Cardiovasc Med 16, 153, 2006.
3. Shirota, T., Yasui, H., and Matsuda, T. Intralumenal tissue-engineered therapeutic stent using endothelial progenitor cell-inoculated hybrid tissue and in vitro performance. Tissue Eng 9, 473, 2003.
4. Thompson, M.M., Budd, J.S., Eady, S.L., Underwood, M.J., James, R.F., and Bell, P.R. The effect of transluminal endo-thelial seeding on myointimal hyperplasia following angio-plasty. Eur J Vasc Surg 8, 423, 1994.
5. Brown, M., Wallace, C.S., and Truskey, G.A. Vascular and capillary endothelium. In: Metin Akay, ed. Wiley Encyclopedia of Biomedical Engineering. John Wiley & Sons I, 2006. DOI: 10.1002/9780471740360.ebs0436.
6. Hutter, R., Carrick, F.E., Valdiviezo, C., Wolinsky, C., Rudge, J.S., Wiegand, S.J., Fuster, V., Badimon, J.J., and Sauter, B.V. Vascular endothelial growth factor regulates reendothelial-ization and neointima formation in a mouse model of arterial injury. Circulation 110, 2430, 2004.
7. Consigny, P.M., and Vitali, N.J. Resistance of freshly adherent endothelial cells to detachment by shear stress is matrix and time dependent. J Vasc Interv Radiol 9, 479, 1998.
8. Schmidt, D., Breymann, C., Weber, A., Guenter, C.I., Neuenschwander, S., Zund, G., Turina, M., and Hoerstrup, S.P. Umbilical cord blood derived endothelial progenitor cells for tissue engineering of vascular grafts. Ann Thorac Surg 78, 2094, 2004.
9. Arts, C.H., Blankensteijn, J.D., Heijnen-Snyder, G.J., Verha-gen, H.J., Hedeman Joosten, P.P., Sixma, J.J., Eikelboom, B.C., and de Groot, P.G. Reduction of non-endothelial cell contamination of microvascular endothelial cell seeded grafts decreases thrombogenicity and intimal hyperplasia. Eur J Vasc Endovasc Surg 23, 404, 2002.
10. He, H., Shirota, T., Yasui, H., and Matsuda, T. Canine en-dothelial progenitor cell-lined hybrid vascular graft with nonthrombogenic potential. J Thorac Cardiovasc Surg 126, 455, 2003.
11. Fuchs, S., Hermanns, M.I., and Kirkpatrick, C.J. Retention of a differentiated endothelial phenotype by outgrowth endo-thelial cells isolated from human peripheral blood and expanded in long-term cultures. Cell Tissue Res 326, 79, 2006.
12. Zammaretti, P., and Zisch, A.H. Adult endothelial progenitor cells. Renewing vasculature. Int J Biochem Cell Biol 37, 493, 2005.
13. Luttun, A., Carmeliet, G., and Carmeliet, P. Vascular progenitors: from biology to treatment. Trends Cardiovasc Med 12, 88, 2002.
14. Dimmeler, S., and Zeiher, A.M. Vascular repair by circulating endothelial progenitor cells: the missing link in atherosclerosis? J Mol Med 82, 671, 2004.
15. Wassmann, S., Werner, N., Czech, T., and Nickenig, G. Improvement of endothelial function by systemic transfusion of vascular progenitor cells. Circ Res 99, e74, 2006.
16. Vemulapalli, S., Metzler, S.D., Akabani, G., Petry, N.A., Niehaus, N.J., Liu, X., Patil, N.H., Greer, K.L., Jaszczak, R.J., Coleman, R.E., Dong, C., Goldschmidt-Clermont, P.J., and Chin, B.B. Cell therapy in murine atherosclerosis: in vivo imaging with high-resolution helical SPECT. Radiology 242, 198, 2007.
17. Rauscher, F.M., Goldschmidt-Clermont, P.J., Davis, B.H., Wang, T., Gregg, D., Ramaswami, P., Pippen, A.M., Annex, B.H., Dong, C., and Taylor, D.A. Aging, progenitor cell exhaustion, and atherosclerosis. Circulation 108, 457, 2003.
18. Dzau, V.J., Gnecchi, M., Pachori, A.S., Morello, F., and Melo, L.G. Therapeutic potential of endothelial progenitor cells in cardiovascular diseases. Hypertension 46, 7, 2005.
19. Ingram, D.A., Mead, L.E., Tanaka, H., Meade, V., Fenoglio, A., Mortell, K., Pollok, J., Ferkowicz, M.J., Gilley, D., and Yoder, M.C. Identification of a novel hierarchy of endothe-lial progenitor cells using human peripheral and umbilical cord blood. Blood 104, 2752, 2004.
20. Ghen, M.J., Roshan, R., Roshan, R.O., Blyweiss, D.J., Corso, N., Khalili, B., and Zenga, W.T. Potential clinical applications using stem cells derived from human umbilical cord blood. Reprod Biomed Online 13, 562, 2006.
21. Zhang, L., Yang, R., and Han, Z.C. Transplantation of umbilical cord blood-derived endothelial progenitor cells: a promising method of therapeutic revascularisation. Eur J Haematol 76, 1, 2006.
22. Jaing, T.H., Yang, C.P., Hung, I.J., Chen, S.H., Sun, C.F., and Chow, R. Transplantation of unrelated donor umbilical cord blood utilizing double-unit grafts for five teenagers with transfusion-dependent thalassemia. Bone Marrow Transplant 40, 307, 2007.
23. Suarez, Y., Shepherd, B.R., Rao, D.A., and Pober, J.S. Al-loimmunity to human endothelial cells derived from cord blood progenitors. J Immunol 179, 7488, 2007.
24. Yang, Z., Tao, J., Wang, J.M., Tu, C., Xu, M.G., Wang, Y., and Pan, S.R. Shear stress contributes to t-PA mRNA expression in human endothelial progenitor cells and nonthrombogenic potential of small diameter artificial vessels. Biochem Bio-phys Res Commun 342, 577, 2006.
25. Ingram, D.A., Krier, T.R., Mead, L.E., McGuire, C., Prater, D.N., Bhavsar, J., Saadatzaden, M.R., Bijangi-Vishehsaraei, K., Yoder, M.C., and Haneline, L.S. Clonogenic endothelial progenitor cells are sensitive to oxidative stress. Stem Cells 25, 297, 2007.
26. Ingram, D.A., Caplice, N.M., and Yoder, M.C. Unresolved questions, changing definitions, and novel paradigms for defining endothelial progenitor cells. Blood 106, 1525, 2005.
27. Yoder, M.C., Mead, L.E., Prater, D., Krier, T.R., Mroueh, K.N., Li, F., Krasich, R., Temm, C.J., Prchal, J.T., and Ingram, D.A. Redefining endothelial progenitor cells via clonal analysis and hematopoietic stem/progenitor cell principals. Blood 109, 1801, 2007.
28. Schmidt, D., Asmis, L.M., Odermatt, B., Kelm, J., Breymann, C., Gossi, M., Genoni, M., Zund, G., and Hoerstrup, S.P. Engineered living blood vessels: functional endothelia generated from human umbilical cord-derived progenitors. Ann Thorac Surg 82, 1465, 2006; discussion 71.
29. Kaushal, S., Amiel, G.E., Guleserian, K.J., Shapira, O.M., Perry, T., Sutherland, F.W., Rabkin, E., Moran, A.M., Schoen, F.J., Atala, A., Soker, S., Bischoff, J., and Mayer, J.E., Jr. Functional small-diameter neovessels created using endothelial progenitor cells expanded ex vivo. Nat Med 7, 1035, 2001.
30. Griese, D.P., Ehsan, A., Melo, L.G., Kong, D., Zhang, L., Mann, M.J., Pratt, R.E., Mulligan, R.C., and Dzau, V.J. Isolation and transplantation of autologous circulating endo-thelial cells into denuded vessels and prosthetic grafts: implications for cell-based vascular therapy. Circulation 108, 2710, 2003.
31. Anamelechi, C.C., Truskey, G.A., and Reichert, W.M. Mylar and Teflon-AF as cell culture substrates for studying endo-thelial cell adhesion. Biomaterials 26, 6887, 2005.
32. Brown, M.A., Wallace, C.S., Anamelechi, C.C., Clermont, E., Reichert, W.M., and Truskey, G.A. The use of mild trypsi-nization conditions in the detachment of endothelial cells to promote subsequent endothelialization on synthetic surfaces. Biomaterials 28, 3928, 2007.
33. Truskey, G.A., and Proulx, T.L. Relationship between 3T3 cell spreading and the strength of adhesion on glass and silane surfaces. Biomaterials 14, 243, 1993.
34. Wallace, C.S., Strike, S.A., and Truskey, G.A. Smooth muscle cell rigidity and extracellular matrix organization influence endothelial cell spreading and adhesion formation in co-culture. Am J Physiol Heart Circ Physiol 293, H1978, 2007.
35. Livak, K.J., and Schmittgen, T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25, 402, 2001
36. Wallace, C.S. Endothelial Cell Adhesion and Function when Co-cultured with Smooth Muscle Cells. Department of Bio-medical Engineering. Durham: Duke University, 2008.
37. Wallace, C.S., Champion, J.C., and Truskey, G.A. Adhesion and function of human endothelial cells co-cultured on smooth muscle cells. Ann Biomed Eng 35, 375, 2007.
38. Yamamoto, K., Takahashi, T., Asahara, T., Ohura, N., Sokabe, T., Kamiya, A., and Ando, J. Proliferation, differentiation, and tube formation by endothelial progenitor cells in response to shear stress. J Appl Physiol 95, 2081, 2003.
39. Ellis, P.D., Metcalfe, J.C., Hyvonen, M., and Kemp, P.R. Adhesion of endothelial cells to NOV is mediated by the integ-rins alphavbeta3 and alpha5beta1. J Vasc Res 40, 234, 2003.
40. Mathur, A.B., Chan, B.P., Truskey, G.A., and Reichert, W.M. High-affinity augmentation of endothelial cell attachment: long-term effects on focal contact and actin filament formation. J Biomed Mater Res A 66, 729, 2003.
41. Gallant, N.D., Michael, K.E., and Garcia, A.J. Cell adhesion strengthening: contributions of adhesive area, integrin binding, and focal adhesion assembly. Mol Biol Cell 16, 4329, 2005.
42. Tao, J., Yang, Z., Wang, J.M., Tu, C., and Pan, S.R. Effects of fluid shear stress on eNOS mRNA expression and NO production in human endothelial progenitor cells. Cardiology 106, 82, 2006.
43. Cines, D.B., Pollak, E.S., Buck, C.A., Loscalzo, J., Zimmerman, G.A., McEver, R.P., Pober, J.S., Wick, T.M., Konkle, B.A., Schwartz, B.S., Barnathan, E.S., McCrae, K.R., Hug, B.A., Schmidt, A.M., and Stern, D.M. Endothelial cells in physiology and in the pathophysiology of vascular disorders. Blood 91, 3527, 1998.
44. Mattsson, E.J., Kohler, T.R., Vergel, S.M., and Clowes, A.W. Increased blood flow induces regression of intimal hyper-plasia. Arterioscler Thromb Vasc Biol 17, 2245, 1997.
45. Brooks, A.R., Lelkes, P.I., and Rubanyi, G.M. Gene expression profiling of human aortic endothelial cells exposed to disturbed flow and steady laminar flow. Physiol Genomics 9, 27, 2002.
46. McCormick, S.M., Eskin, S.G., McIntire, L.V., Teng, C.L., Lu, C.M., Russell, C.G., and Chittur, K.K. DNA microarray reveals changes in gene expression of shear stressed human umbilical vein endothelial cells. Proc Natl Acad Sci USA 98, 8955, 2001.
47. Muscari, C., Gamberini, C., Carboni, M., Basile, I., Farruggia, G., Bonafe, F., Giordano, E., Caldarera, C.M., and Guarnieri, C. Different expression of NOS isoforms in early endothelial progenitor cells derived from peripheral and cord blood. J Cell Biochem 102, 992, 2007.
48. Motley, E.D., Eguchi, K., Patterson, M.M., Palmer, P.D., Suzuki, H., and Eguchi, S. Mechanism of endothelial nitric oxide synthase phosphorylation and activation by thrombin. Hypertension 49, 577, 2007.
49. Papadaki, M., Tilton, R.G., Eskin, S.G., and McIntire, L.V. Nitric oxide production by cultured human aortic smooth muscle cells: stimulation by fluid flow. Am J Physiol 274, H616, 1998.
50. Fernandez, P., Bourget, C., Bareille, R., Daculsi, R., and Bordenave, L. Gene response in endothelial cells cultured on engineered surfaces is regulated by shear stress. Tissue Eng 13, 1607, 2007.
51. Lin, Z., Kumar, A., SenBanerjee, S., Staniszewski, K., Parmar, K., Vaughan, D.E., Gimbrone, M.A., Jr., Balasubramanian, V., Garcia-Cardena, G., and Jain, M.K. Kruppel-like factor 2 (KLF2) regulates endothelial thrombotic function. Circ Res 96, e48, 2005.
52. Yasui, M., Yamamoto, H., Ngan, C.Y., Damdinsuren, B., Sugita, Y., Fukunaga, H., Gu, J., Maeda, M., Takemasa, I., Ikeda, M., Fujio, Y., Sekimoto, M., Matsuura, N., Weinstein, I.B., and Monden, M. Antisense to cyclin D1 inhibits vascular endothelial growth factor-stimulated growth of vascular endothelial cells: implication of tumor vascularization. Clin Cancer Res 12, 4720, 2006.
53. Ley, K., Laudanna, C., Cybulsky, M.I., and Nourshargh, S. Getting to the site of inflammation: the leukocyte adhesion cascade updated. Nat Rev Immunol 7, 678, 2007.
54. Chiu, J.J., Lee, P.L., Chen, C.N., Lee, C.I., Chang, S.F., Chen, L.J., Lien, S.C., Ko, Y.C., Usami, S., and Chien, S. Shear stress increases ICAM-1 and decreases VCAM-1 and E-selectin expressions induced by tumor necrosis factor-[alpha] in endothelial cells. Arterioscler Thromb Vasc Biol 24, 73, 2004