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Volumn 40, Issue 16, 2012, Pages 7844-7857

Genome-wide localization and expression profiling establish Sp2 as a sequence-specific transcription factor regulating vitally important genes

Author keywords

[No Author keywords available]

Indexed keywords

DNA; SMALL INTERFERING RNA; STAT1 PROTEIN; TRANSCRIPTION FACTOR SP2; TRANSFERRIN BINDING PROTEIN;

EID: 84870504580     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gks544     Document Type: Article
Times cited : (38)

References (46)
  • 1
    • 0032866999 scopus 로고    scopus 로고
    • The Sp-family of transcription factors
    • Suske, G. (1999) The Sp-family of transcription factors. Gene, 238, 291-300.
    • (1999) Gene , vol.238 , pp. 291-300
    • Suske, G.1
  • 2
    • 16244405603 scopus 로고    scopus 로고
    • Mammalian SP/KLF transcription factors: Bring in the family
    • Suske, G., Bruford, E. and Philipsen, S. (2005) Mammalian SP/KLF transcription factors: bring in the family. Genomics, 85, 551-556.
    • (2005) Genomics , vol.85 , pp. 551-556
    • Suske, G.1    Bruford, E.2    Philipsen, S.3
  • 3
    • 77950456854 scopus 로고    scopus 로고
    • A clustered set of three Sp-family genes is ancestral in the Metazoa: Evidence from sequence analysis, protein domain structure, developmental expression patterns and chromosomal location
    • Schaeper, N.D., Prpic, N.M. and Wimmer, E.A. (2010) A clustered set of three Sp-family genes is ancestral in the Metazoa: evidence from sequence analysis, protein domain structure, developmental expression patterns and chromosomal location. BMC Evolut. Biol., 10, 88.
    • (2010) BMC Evolut. Biol. , vol.10 , pp. 88
    • Schaeper, N.D.1    Prpic, N.M.2    Wimmer, E.A.3
  • 4
    • 0030853287 scopus 로고    scopus 로고
    • Transcription factor Sp1 is essential for early development but dispensable for cell growth and differentiation
    • Marin, M., Karis, A., Visser, P., Grosveld, F. and Philipsen, S. (1997) Transcription factor Sp1 is essential for early development but dispensable for cell growth and differentiation. Cell, 89, 619-628.
    • (1997) Cell , vol.89 , pp. 619-628
    • Marin, M.1    Karis, A.2    Visser, P.3    Grosveld, F.4    Philipsen, S.5
  • 6
    • 0034920371 scopus 로고    scopus 로고
    • Impaired ossification in mice lacking the transcription factor Sp3
    • Göllner, H., Dani, C., Phillips, B., Philipsen, S. and Suske, G. (2001) Impaired ossification in mice lacking the transcription factor Sp3. Mech. Dev., 106, 77-83.
    • (2001) Mech. Dev. , vol.106 , pp. 77-83
    • Göllner, H.1    Dani, C.2    Phillips, B.3    Philipsen, S.4    Suske, G.5
  • 8
    • 34548080331 scopus 로고    scopus 로고
    • Sp1/Sp3 compound heterozygous mice are not viable: Impaired erythropoiesis and severe placental defects
    • Krüger, I., Vollmer, M., Simmons, D.G., Elsässer, H.P., Philipsen, S. and Suske, G. (2007) Sp1/Sp3 compound heterozygous mice are not viable: impaired erythropoiesis and severe placental defects. Dev. Dyn., 236, 2235-2244.
    • (2007) Dev. Dyn. , vol.236 , pp. 2235-2244
    • Krüger, I.1    Vollmer, M.2    Simmons, D.G.3    Elsässer, H.P.4    Philipsen, S.5    Suske, G.6
  • 9
    • 0029944159 scopus 로고    scopus 로고
    • Sp4, a member of the Sp1-family of zinc finger transcription factors, is required for normal murine growth, viability, and male fertility
    • Supp, D.M., Witte, D.P., Branford, W.W., Smith, E.P. and Potter, S.S. (1996) Sp4, a member of the Sp1-family of zinc finger transcription factors, is required for normal murine growth, viability, and male fertility. Dev. Biol., 176, 284-299.
    • (1996) Dev. Biol. , vol.176 , pp. 284-299
    • Supp, D.M.1    Witte, D.P.2    Branford, W.W.3    Smith, E.P.4    Potter, S.S.5
  • 13
    • 16844371331 scopus 로고    scopus 로고
    • Reduced expression of the Sp4 gene in mice causes deficits in sensorimotor gating and memory associated with hippocampal vacuolization
    • Zhou, X., Long, J.M., Geyer, M.A., Masliah, E., Kelsoe, J.R., Wynshaw-Boris, A. and Chien, K.R. (2005) Reduced expression of the Sp4 gene in mice causes deficits in sensorimotor gating and memory associated with hippocampal vacuolization. Mol. Psychiatry, 10, 393-406.
    • (2005) Mol. Psychiatry , vol.10 , pp. 393-406
    • Zhou, X.1    Long, J.M.2    Geyer, M.A.3    Masliah, E.4    Kelsoe, J.R.5    Wynshaw-Boris, A.6    Chien, K.R.7
  • 14
    • 34247095646 scopus 로고    scopus 로고
    • Impaired postnatal development of hippocampal dentate gyrus in Sp4 null mutant mice
    • Zhou, X., Qyang, Y., Kelsoe, J.R., Masliah, E. and Geyer, M.A. (2007) Impaired postnatal development of hippocampal dentate gyrus in Sp4 null mutant mice. Genes Brain Behav., 6, 269-276.
    • (2007) Genes Brain Behav. , vol.6 , pp. 269-276
    • Zhou, X.1    Qyang, Y.2    Kelsoe, J.R.3    Masliah, E.4    Geyer, M.A.5
  • 16
    • 78449302869 scopus 로고    scopus 로고
    • Overexpression of transcription factor sp2 inhibits epidermal differentiation and increases susceptibility to wound-and carcinogen-induced tumorigenesis
    • Kim, T.H., Chiera, S.L., Linder, K.E., Trempus, C.S., Smart, R.C. and Horowitz, J.M. (2010) Overexpression of Transcription Factor Sp2 Inhibits Epidermal Differentiation and Increases Susceptibility to Wound-and Carcinogen-Induced Tumorigenesis. Cancer Res., 70, 8507-8516.
    • (2010) Cancer Res. , vol.70 , pp. 8507-8516
    • Kim, T.H.1    Chiera, S.L.2    Linder, K.E.3    Trempus, C.S.4    Smart, R.C.5    Horowitz, J.M.6
  • 17
    • 1842790975 scopus 로고    scopus 로고
    • Sp2 DNA binding activity and trans-activation are negatively regulated in mammalian cells
    • Moorefield, K.S., Fry, S.J. and Horowitz, J.M. (2004) Sp2 DNA binding activity and trans-activation are negatively regulated in mammalian cells. J. Biol. Chem., 279, 13911-13924.
    • (2004) J. Biol. Chem. , vol.279 , pp. 13911-13924
    • Moorefield, K.S.1    Fry, S.J.2    Horowitz, J.M.3
  • 19
    • 0027965294 scopus 로고
    • Sp1-mediated transcriptional activation is repressed by Sp3
    • Hagen, G., Müller, S., Beato, M. and Suske, G. (1994) Sp1-mediated transcriptional activation is repressed by Sp3. EMBO J., 13, 3843-3851.
    • (1994) EMBO J. , vol.13 , pp. 3843-3851
    • Hagen, G.1    Müller, S.2    Beato, M.3    Suske, G.4
  • 20
    • 0000272784 scopus 로고
    • The use of gel electrophoresis to detect and study nucleic acid-protein interactions
    • Garner, M.M. and Revzin, A. (1986) The use of gel electrophoresis to detect and study nucleic acid-protein interactions. TIBS, 11, 395-396.
    • (1986) TIBS , vol.11 , pp. 395-396
    • Garner, M.M.1    Revzin, A.2
  • 21
    • 0026474531 scopus 로고
    • Cloning by recognition site screening of two novel GT box binding proteins: A family of Sp1 related genes
    • Hagen, G., Müller, S., Beato, M. and Suske, G. (1992) Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes. Nucleic Acids Res., 20, 5519-5525.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 5519-5525
    • Hagen, G.1    Müller, S.2    Beato, M.3    Suske, G.4
  • 22
    • 0035931856 scopus 로고    scopus 로고
    • RB regulates transcription of the p21/WAF1/CIP1 gene
    • Decesse, J.T., Medjkane, S., Datto, M.B. and Cremisi, C.E. (2001) RB regulates transcription of the p21/WAF1/CIP1 gene. Oncogene, 20, 962-971.
    • (2001) Oncogene , vol.20 , pp. 962-971
    • Decesse, J.T.1    Medjkane, S.2    Datto, M.B.3    Cremisi, C.E.4
  • 23
    • 51049083598 scopus 로고    scopus 로고
    • SUMO-modified Sp3 represses transcription by provoking local heterochromatic gene silencing
    • Stielow, B., Sapetschnig, A., Wink, C., Krüger, I. and Suske, G. (2008) SUMO-modified Sp3 represses transcription by provoking local heterochromatic gene silencing. EMBO Rep., 9, 899-906.
    • (2008) EMBO Rep. , vol.9 , pp. 899-906
    • Stielow, B.1    Sapetschnig, A.2    Wink, C.3    Krüger, I.4    Suske, G.5
  • 25
    • 62349130698 scopus 로고    scopus 로고
    • Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
    • Langmead, B., Trapnell, C., Pop, M. and Salzberg, S.L. (2009) Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol., 10, R25.
    • (2009) Genome Biol. , vol.10
    • Langmead, B.1    Trapnell, C.2    Pop, M.3    Salzberg, S.L.4
  • 27
    • 0028685490 scopus 로고
    • Fitting a mixture model by expectation maximization to discover motifs in biopolymers
    • Bailey, T.L. and Elkan, C. (1994) Fitting a mixture model by expectation maximization to discover motifs in biopolymers. Proc. Int. Conf. ISMB, 2, 28-36.
    • (1994) Proc. Int. Conf. ISMB , vol.2 , pp. 28-36
    • Bailey, T.L.1    Elkan, C.2
  • 29
    • 0001677717 scopus 로고
    • Controllng the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini, Y. and Hochberg, Y. (1995) Controllng the false discovery rate: a practical and powerful approach to multiple testing. J. Roy. Statist. Soc. Ser B, 57, 289-300.
    • (1995) J. Roy. Statist. Soc. ser B , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 32
    • 58149200952 scopus 로고    scopus 로고
    • UniPROBE: An online database of protein binding microarray data on protein-DNA interactions
    • Newburger, D.E. and Bulyk, M.L. (2009) UniPROBE: an online database of protein binding microarray data on protein-DNA interactions. Nucleic Acids Res., 37, D77-D82.
    • (2009) Nucleic Acids Res. , vol.37
    • Newburger, D.E.1    Bulyk, M.L.2
  • 33
    • 58549112996 scopus 로고    scopus 로고
    • Bioinformatics enrichment tools: Paths toward the comprehensive functional analysis of large gene lists
    • Huang da, W., Sherman, B.T. and Lempicki, R.A. (2009) Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res., 37, 1-13.
    • (2009) Nucleic Acids Res. , vol.37 , pp. 1-13
    • Huang Da, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 36
    • 79954562232 scopus 로고    scopus 로고
    • Regulating RNA polymerase pausing and transcription elongation in embryonic stem cells
    • Min, I.M., Waterfall, J.J., Core, L.J., Munroe, R.J., Schimenti, J. and Lis, J.T. (2011) Regulating RNA polymerase pausing and transcription elongation in embryonic stem cells. Genes Dev., 25, 742-754.
    • (2011) Genes Dev. , vol.25 , pp. 742-754
    • Min, I.M.1    Waterfall, J.J.2    Core, L.J.3    Munroe, R.J.4    Schimenti, J.5    Lis, J.T.6
  • 40
    • 39449089350 scopus 로고    scopus 로고
    • DNA damage repair and response proteins as targets for cancer therapy
    • Lieberman, H.B. (2008) DNA damage repair and response proteins as targets for cancer therapy. Curr. Medicin. Chem., 15, 360-367.
    • (2008) Curr. Medicin. Chem. , vol.15 , pp. 360-367
    • Lieberman, H.B.1
  • 41
    • 0036251153 scopus 로고    scopus 로고
    • SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
    • Horton, J.D., Goldstein, J.L. and Brown, M.S. (2002) SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J. Clin. Invest., 109, 1125-1131.
    • (2002) J. Clin. Invest. , vol.109 , pp. 1125-1131
    • Horton, J.D.1    Goldstein, J.L.2    Brown, M.S.3
  • 42
    • 0026756135 scopus 로고
    • Cloning of GT box-binding proteins: A novel Sp1 multigene family regulating T-cell receptor gene expression
    • Kingsley, C. and Winoto, A. (1992) Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expression. Mol. Cell. Biol., 12, 4251-4261.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 4251-4261
    • Kingsley, C.1    Winoto, A.2
  • 43
    • 48249123867 scopus 로고    scopus 로고
    • Genome-wide occupancy of SREBP1 and its partners NFY and SP1 reveals novel functional roles and combinatorial regulation of distinct classes of genes
    • Reed, B.D., Charos, A.E., Szekely, A.M., Weissman, S.M. and Snyder, M. (2008) Genome-wide occupancy of SREBP1 and its partners NFY and SP1 reveals novel functional roles and combinatorial regulation of distinct classes of genes. PLoS Genet., 4, e1000133.
    • (2008) PLoS Genet. , vol.4
    • Reed, B.D.1    Charos, A.E.2    Szekely, A.M.3    Weissman, S.M.4    Snyder, M.5
  • 44
    • 7444260846 scopus 로고    scopus 로고
    • The encode (ENCyclopedia of DNA Elements) project
    • Consortium, E.P. (2004) The ENCODE (ENCyclopedia Of DNA Elements) project. Science, 306, 636-640.
    • (2004) Science , vol.306 , pp. 636-640
    • Consortium, E.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.