Overexpression of transcription factor Sp2 inhibits epidermal differentiation and increases susceptibility to wound- and carcinogen-induced tumorigenesis

Cancer Research

Volumn 70, Issue 21, 2010, Pages 8507-8516

  Kim, Tae Hyung ^a   Chiera, Shannon L ^a   Linder, Keith E ^a   Trempus, Carol S ^b   Smart, Robert C ^a   Horowitz, Jonathan M ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGEN; TRANSCRIPTION FACTOR SP2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CELL DIFFERENTIATION; CELL FUNCTION; CONTROLLED STUDY; DISEASE PREDISPOSITION; ENZYME INHIBITION; EPIDERMIS CELL; HEMIZYGOTE; HOMOZYGOTE; HUMAN; KERATINOCYTE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA; TRANSGENE; TUMOR GROWTH; WOUND;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; BLOTTING, WESTERN; CARCINOGENS; CARCINOMA, SQUAMOUS CELL; CATTLE; CELL DIFFERENTIATION; CERCOPITHECUS AETHIOPS; COS CELLS; DISEASE SUSCEPTIBILITY; EPIDERMIS; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; KERATIN-5; KERATINOCYTES; MALE; MICE; MICE, TRANSGENIC; PROMOTER REGIONS, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SKIN NEOPLASMS; SP2 TRANSCRIPTION FACTOR; WOUNDS AND INJURIES;

EID: 78449302869     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-10-1213     Document Type: Article

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