GSTT1, GSTM1, and CYP1B1 gene polymorphisms and susceptibility to sporadic renal cell cancer

Urologic Oncology: Seminars and Original Investigations

Volumn 30, Issue 6, 2012, Pages 864-870

  Salinas Sánchez, Antonio S ^a   Sánchez Sánchez, Francisco ^b   Donate Moreno, María J ^a   Rubio del Campo, Antonio ^a   Serrano Oviedo, Leticia ^a   Gimenez Bachs, José M ^a   Martínez Sanchiz, Carlos ^a   Segura Martín, Miguel ^a   Escribano, Julio ^b  

^a Hospital and University Complex of Albacete   (Spain)

^b UNIVERSITY OF CASTILLA LA MANCHA   (Spain)

Author keywords

CYP1B1; Cytochrome p450; Glutathione S transferase; GSTM1; GSTT1; Prognosis; Renal cell carcinoma

Indexed keywords

ALANINE; VALINE;

ADULT; ANATOMY; ARTICLE; CANCER STAGING; CONFIDENCE INTERVAL; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; CYTOCHROME P450 1B1 GENE; DEMOGRAPHY; DNA POLYMORPHISM; FEMALE; GENE; GENE DELETION; GENE SEQUENCE; GENETIC SUSCEPTIBILITY; GENOTYPE; GLUTATHIONE TRANSFERASE M1 GENE; GLUTATHIONE TRANSFERASE T1 GENE; HOSPITAL; HUMAN; KIDNEY CARCINOMA; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MULTIPLEX POLYMERASE CHAIN REACTION; PATHOLOGY; PREVALENCE; PRIORITY JOURNAL; RISK;

ARYL HYDROCARBON HYDROXYLASES; CARCINOMA, RENAL CELL; CROSS-SECTIONAL STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GLUTATHIONE TRANSFERASE; HUMANS; KIDNEY NEOPLASMS; MULTIPLEX POLYMERASE CHAIN REACTION; NEOPLASM GRADING; NEOPLASM STAGING; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84870503030     PISSN: 10781439     EISSN: 18732496     Source Type: Journal    
DOI: 10.1016/j.urolonc.2010.10.001     Document Type: Article

References (30)

1. Landis S.H., Murray T., Bolden S., et al. Cancer statistics: 1999. CA Cancer J Clin 1999, 49:8-31.
2. López-Abente G., Ramis R., Pollán M., et al. Atlas Municipal de mortalidad por cáncer en España, 1989-1998 2007, Instituto de Salud Carlos III. http://www.isciii.es/jsps/centros/epidemiologia/libros.jsp.
3. Fleming S. Genetics of renal tumors. Cancer Metas Rev 1997, 16:127-140.
4. Giménez Bachs J.M., Salinas Sánchez A.S., Sánchez Sánchez F., et al. Determination of VHL gene mutations in sporadic renal cell carcinoma. Eur Urol 2006, 49:1051-1057.
5. Kenck C., Wilhelm M., Bugert P., et al. Mutation of the VHL gene is associated exclusively with the development of nonpapillary renal cell carcinomas. J Pathol 1996, 179:157-161.
6. Anglada Curado F.J., Campos Hernández P., Prieto Castro R., et al. Nuevos patrones epidemiológicos y factores de riesgo en cáncer renal. Actas Urol Esp 2009, 33:459-467.
7. Eaton D.L., Bammer T.K. Concise review of the glutathione S-transferases and their significance to toxicology. Toxicol Sci 1999, 49:156-164.
8. Raunio H., Husgafvel-Pursiainen K., Anttila E., et al. Diagnosis of polymorphisms in carcinogen-activating and inactivating enzymes and cancer susceptibility: A review. Gene 1995, 159:113-121.
9. Roots I., Brockmoller J., Drakoulis N., et al. Mutant genes of cytochrome P-450IID6, glutathione S-transferase class μ, and arylamine N-acetyltransferase in lung cancer patients. Clin Investig 1992, 70:307-319.
10. Perera F.P. Environment and cancer: Who are susceptible?. Science 1997, 278:1068-1073.
11. Pemble S., Schroeder K.R., Spencer S.R., et al. Human glutathione S-transferase theta (GSTT1): cDNA cloning and the characterization of a genetic polymorphism. Biochem J 1994, 300(Pt1):271-276.
12. Seidegård J., Pero R.W., Miller D.G., et al. A glutathione transferase in human leukocytes as a marker for the susceptibility to lung cancer. Carcinogenesis 1986, 7:751-753.
13. Ingelman-Sundberg M. Human drug metabolizing cytochrome P450 enzymes: Properties and polymorphisms. Naunyn Schmiedebergs Arch Pharmacol 2004, 369:89-104.
14. Gonzalez F.J., Kimura S. Understanding the role of xenobiotic-metabolism in chemical carcinogenesis using gene knockout mice. Mutat Res 2001, 477:79-87.
15. Thier R., Bruning T., Roos P.H., et al. Markers of genetic susceptibility in human environmental hygiene and toxicology: The role of selected CYP, NAT, and GST genes. Int J Hyg Environ Health 2003, 206:149-171.
16. Gonzalez F.J., Kimura S. Role of gene knockout mice in understanding the mechanisms of chemical toxicity and carcinogenesis. Cancer Lett 1999, 143:199-204.
17. Agundez J.A. Cytochrome P450 gene polymorphism and cancer. Curr Drug Metab 2004, 5:211-224.
18. Sprenger R., Schlagenhaufer R., Kerb R., et al. Characterization of the glutathione S-transferase GSTT1 deletion: Discrimination of all genotypes by polymerase chain reaction indicates a trimodular genotype-phenotype correlation. Pharmacogenetics 2000, 10:557-565.
19. López-Garrido M.P., Sánchez-Sánchez F., López-Martínez F., et al. Heterozygous CYP1B1 gene mutations in Spanish patients with primary open-angle glaucoma. Mol Vis 2006, 12:748-755.
20. Simic T., Savic-Radojevic A., Pljesa-Ercegovac M., et al. Glutathione S-transferases in kidney and urinary bladder tumors. Nat Rev Urol 2009, 6:281-289.
21. Sweeney C., Farrow D.C., Schwartz S.M., et al. Glutathione S-transferase M1, T1, and P1 polymorphisms as risk factors for renal cell carcinoma: A case-control study. Cancer Epidemiol Biomarkers Prev 2000, 9:449-454.
22. De Martino M., Klatte T., Schatzl G., et al. Renal cell carcinoma Fuhrman grade and histological subtype correlate with complete polymorphic deletion of glutathione S-transferase M1 gene. J Urol 2010, 183:878-883.
23. Brüning T., Lammert M., Kempkes M., et al. Influence of polymorphisms of GSTM1 and GSTT1 for risk of renal cell cancer in workers with long-term high occupational exposure to trichloroethene. Arch Toxicol 1997, 71:596-599.
24. Wiesenhütter B., Selinski S., Golka K., et al. Reassessment of the influence of polymorphisms of phase-II metabolic enzymes on renal cell cancer risk of trichloroethylene-exposed workers. Int Arch Occup Environ Health 2007, 81:247-251.
25. Sasaki M., Tanaka Y., Okino S.T., et al. Polymorphism of the CYP1B1 gene as risk for human renal cell carcinoma. Clin Cancer Res 2004, 10:2015-2019.
26. Rintala S., Tammela T.L., Tuimala R. CYP1A1 activity in renal cell carcinoma and in adjacent normal renal tissue. Urol Res 1998, 26:117-121.
27. Longuemaux S., Deloménie C., Gallou C., et al. Candidate genetic modifiers of individual susceptibility to renal cell carcinoma: A study of polymorphic human xenobiotic-metabolizing enzymes. Cancer Res 1999, 59:2903-2908.
28. Delbanco E.H., Bolt H.M., Huber W.W., et al. Glutathione transferase activities in renal carcinomas and adjacent normal renal tissues: Factors influencing renal carcinogenesis induced by xenobiotics. Arch Toxicol 2001, 74:688-694.
29. Cho S.G., Lee Y.H., Park H.S., et al. Glutathione S-transferase μ modulates the stress-activated signals by suppressing apoptosis signal-regulating kinase 1. J Biol Chem 2001, 276:12749-12755.
30. McFadyen M.C., Melvin W.T., Murray G.I. Cytochrome P450 CYP1B1 activity in renal cell carcinoma. Br J Cancer 2004, 91:966-971.