Plant stanols induce intestinal tumor formation by up-regulating Wnt and EGFR signaling in ApcMin mice

Journal of Nutritional Biochemistry

Volumn 24, Issue 1, 2013, Pages 343-352

  Marttinen, Maija ^a   Päivärinta, Essi ^a   Storvik, Markus ^b   Huikko, Laura ^a   Luoma Halkola, Heli ^a   Piironen, Vieno ^a   Pajari, Anne Maria ^a   Mutanen, Marja ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

catenin; ApcMin mouse; Cholesterol synthesis; EGFR; Plant sterols

Indexed keywords

BETA CATENIN; BRASSICASTEROL; CAMPESTANOL; CAMPESTEROL; CHOLESTEROL; CYCLIN D1; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SERINE; SITOSTANOL; SITOSTEROL; STANOZOLOL; STEROL; VASCULOTROPIN RECEPTOR; WNT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASH; CALORIC INTAKE; CARBOHYDRATE INTAKE; CARCINOGENESIS; CECUM; CELL NUCLEUS; CHOLESTEROL SYNTHESIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIETARY INTAKE; FAT INTAKE; FEMALE; FLUID INTAKE; GENE EXPRESSION; INTESTINE MUCOSA; INTESTINE POLYP; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN INTAKE; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR VOLUME; UPREGULATION; WESTERN BLOTTING;

ADENOMA; ANIMALS; BETA CATENIN; CECUM; CHOLESTEROL; CYCLIN D1; FEMALE; GENE EXPRESSION REGULATION; GENES, APC; INTESTINAL MUCOSA; INTESTINAL NEOPLASMS; MALE; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHYTOSTEROLS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, EPIDERMAL GROWTH FACTOR; SERINE; SITOSTEROLS; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; UP-REGULATION; WNT SIGNALING PATHWAY;

MUS;

EID: 84870465805     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2012.07.002     Document Type: Article

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