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Volumn 228, Issue 3, 2013, Pages 581-589

Thrombin induces slug-mediated E-cadherin transcriptional repression and the parallel Up-regulation of N-cadherin by a transcription-independent mechanism in RPE cells

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; NERVE CELL ADHESION MOLECULE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE C ZETA; PROTEINASE ACTIVATED RECEPTOR 1; THROMBIN; TRANSCRIPTION FACTOR SLUG; UVOMORULIN;

EID: 84870404772     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.24165     Document Type: Article
Times cited : (35)

References (52)
  • 1
    • 67650996280 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions: The importance of changing cell state in development and disease
    • Acloque H, Adams MS, Fishwick K, Bronner-Fraser M, Nieto MA. 2009. Epithelial-mesenchymal transitions: The importance of changing cell state in development and disease. J Clin Invest 119:1438-1449.
    • (2009) J Clin Invest , vol.119 , pp. 1438-1449
    • Acloque, H.1    Adams, M.S.2    Fishwick, K.3    Bronner-Fraser, M.4    Nieto, M.A.5
  • 2
    • 33645733588 scopus 로고    scopus 로고
    • N-cadherin gene expression in prostate carcinoma is modulated by integrin-dependent nuclear translocation of Twist1
    • Alexander NR, Tran NL, Rekapally H, Summers CE, Glackin C, Heimark RL. 2006. N-cadherin gene expression in prostate carcinoma is modulated by integrin-dependent nuclear translocation of Twist1. Cancer Res 66:3365-3369.
    • (2006) Cancer Res , vol.66 , pp. 3365-3369
    • Alexander, N.R.1    Tran, N.L.2    Rekapally, H.3    Summers, C.E.4    Glackin, C.5    Heimark, R.L.6
  • 3
    • 0037326569 scopus 로고    scopus 로고
    • The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: A comparison with Snail and E47 repressors
    • Bolos V, Peinado H, Perez-Moreno MA, Fraga MF, Esteller M, Cano A. 2003. The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: A comparison with Snail and E47 repressors. J Cell Sci 116:499-511.
    • (2003) J Cell Sci , vol.116 , pp. 499-511
    • Bolos, V.1    Peinado, H.2    Perez-Moreno, M.A.3    Fraga, M.F.4    Esteller, M.5    Cano, A.6
  • 4
    • 0032759730 scopus 로고    scopus 로고
    • Expression of E-cadherin by human retinal pigment epithelium: Delayed expression in vitro
    • Burke JM, Cao F, Irving PE, Skumatz CM. 1999. Expression of E-cadherin by human retinal pigment epithelium: Delayed expression in vitro. Invest Ophthalmol Vis Sci 40:2963-2970.
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , pp. 2963-2970
    • Burke, J.M.1    Cao, F.2    Irving, P.E.3    Skumatz, C.M.4
  • 5
    • 0031056197 scopus 로고    scopus 로고
    • Pathogenic mechanisms in proliferative vitreoretinopathy
    • Campochiaro PA. 1997. Pathogenic mechanisms in proliferative vitreoretinopathy. Arch Ophthalmol 115:237-241.
    • (1997) Arch Ophthalmol , vol.115 , pp. 237-241
    • Campochiaro, P.A.1
  • 8
    • 0032841562 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in proliferative vitreoretinopathy: Intermediate filament protein expression in retinal pigment epithelial cells
    • Casaroli-Marano RP, Pagan R, Vilaro S. 1999. Epithelial-mesenchymal transition in proliferative vitreoretinopathy: Intermediate filament protein expression in retinal pigment epithelial cells. Invest Ophthalmol Vis Sci 40:2062-2072.
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , pp. 2062-2072
    • Casaroli-Marano, R.P.1    Pagan, R.2    Vilaro, S.3
  • 9
    • 79251515143 scopus 로고    scopus 로고
    • Thrombin induces expression of twist and cell motility via the hypoxia-inducible factor-1alpha translational pathway in colorectal cancer cells
    • Chang LH, Chen CH, Huang DY, Pai HC, Pan SL, Teng CM. 2011. Thrombin induces expression of twist and cell motility via the hypoxia-inducible factor-1alpha translational pathway in colorectal cancer cells. J Cell Physiol 226:1060-1068.
    • (2011) J Cell Physiol , vol.226 , pp. 1060-1068
    • Chang, L.H.1    Chen, C.H.2    Huang, D.Y.3    Pai, H.C.4    Pan, S.L.5    Teng, C.M.6
  • 10
    • 77952007543 scopus 로고    scopus 로고
    • Mammalian target of rapamycin (mTOR): Conducting the cellular signaling symphony
    • Foster KG, Fingar DC. 2010. Mammalian target of rapamycin (mTOR): Conducting the cellular signaling symphony. J Biol Chem 285:14071-14077.
    • (2010) J Biol Chem , vol.285 , pp. 14071-14077
    • Foster, K.G.1    Fingar, D.C.2
  • 11
    • 79959593682 scopus 로고    scopus 로고
    • Structural basis of thrombin-protease-activated receptor interactions
    • Gandhi PS, Chen Z, Appelbaum E, Zapata F, Di Cera E. 2011. Structural basis of thrombin-protease-activated receptor interactions. IUBMB Life 63:375-382.
    • (2011) IUBMB Life , vol.63 , pp. 375-382
    • Gandhi, P.S.1    Chen, Z.2    Appelbaum, E.3    Zapata, F.4    Di Cera, E.5
  • 12
    • 34248377348 scopus 로고    scopus 로고
    • Vitreous modulation of gene expression in low-passage human retinal pigment epithelial cells
    • Ganti R, Hunt RC, Parapuram SK, Hunt DM. 2007. Vitreous modulation of gene expression in low-passage human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci 48:1853-1863.
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 1853-1863
    • Ganti, R.1    Hunt, R.C.2    Parapuram, S.K.3    Hunt, D.M.4
  • 13
    • 0028813531 scopus 로고
    • Transdifferentiation of retinal pigment epithelial cells from epithelial to mesenchymal phenotype
    • Grisanti S, Guidry C. 1995. Transdifferentiation of retinal pigment epithelial cells from epithelial to mesenchymal phenotype. Invest Ophthalmol Vis Sci 36:391-405.
    • (1995) Invest Ophthalmol Vis Sci , vol.36 , pp. 391-405
    • Grisanti, S.1    Guidry, C.2
  • 14
    • 84861594264 scopus 로고    scopus 로고
    • Cadherin switch from E- to N-Cadherin in melanoma progression is regulated by the PI3K/PTEN Pathway through TWIST and SNAIL
    • Hao L, Ha JR, Kuzel P, Garcia E, Persad S. 2012. Cadherin switch from E- to N-Cadherin in melanoma progression is regulated by the PI3K/PTEN Pathway through TWIST and SNAIL. Br J Dermatol 166:1184-1197.
    • (2012) Br J Dermatol , vol.166 , pp. 1184-1197
    • Hao, L.1    Ha, J.R.2    Kuzel, P.3    Garcia, E.4    Persad, S.5
  • 17
    • 0033197879 scopus 로고    scopus 로고
    • SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein
    • Inukai T, Inoue A, Kurosawa H, Goi K, Shinjyo T, Ozawa K, Mao M, Inaba T, Look AT. 1999. SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein. Mol Cell 4:343-352.
    • (1999) Mol Cell , vol.4 , pp. 343-352
    • Inukai, T.1    Inoue, A.2    Kurosawa, H.3    Goi, K.4    Shinjyo, T.5    Ozawa, K.6    Mao, M.7    Inaba, T.8    Look, A.T.9
  • 18
    • 84857546522 scopus 로고    scopus 로고
    • Nox1 transactivation of epidermal growth factor receptor promotes N-cadherin shedding and smooth muscle cell migration
    • Jagadeesha DK, Takapoo M, Banfi B, Bhalla RC, Miller FJ, Jr. 2012. Nox1 transactivation of epidermal growth factor receptor promotes N-cadherin shedding and smooth muscle cell migration. Cardiovasc Res 93:406-413.
    • (2012) Cardiovasc Res , vol.93 , pp. 406-413
    • Jagadeesha, D.K.1    Takapoo, M.2    Banfi, B.3    Bhalla, R.C.4    Miller Jr., F.J.5
  • 20
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • Kalluri R, Weinberg RA. 2009. The basics of epithelial-mesenchymal transition. J Clin Invest 119:1420-1428.
    • (2009) J Clin Invest , vol.119 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 21
    • 79955545737 scopus 로고    scopus 로고
    • Mature peripheral RPE cells have an intrinsic capacity to proliferate; a potential regulatory mechanism for age-related cell loss
    • Kokkinopoulos I, Shahabi G, Colman A, Jeffery G. 2011. Mature peripheral RPE cells have an intrinsic capacity to proliferate; a potential regulatory mechanism for age-related cell loss. PLoS ONE 6:e18921.
    • (2011) PLoS ONE , vol.6
    • Kokkinopoulos, I.1    Shahabi, G.2    Colman, A.3    Jeffery, G.4
  • 22
    • 30544454763 scopus 로고    scopus 로고
    • Influence of the cytoplasmic domain of E-cadherin on endogenous N-cadherin expression in malignant melanoma
    • Kuphal S, Bosserhoff AK. 2006. Influence of the cytoplasmic domain of E-cadherin on endogenous N-cadherin expression in malignant melanoma. Oncogene 25:248-259.
    • (2006) Oncogene , vol.25 , pp. 248-259
    • Kuphal, S.1    Bosserhoff, A.K.2
  • 23
    • 80051519486 scopus 로고    scopus 로고
    • Snail involves in the transforming growth factor beta1-mediated epithelial-mesenchymal transition of retinal pigment epithelial cells
    • Li H, Wang H, Wang F, Gu Q, Xu X. 2011. Snail involves in the transforming growth factor beta1-mediated epithelial-mesenchymal transition of retinal pigment epithelial cells. PLoS ONE 6:e23322.
    • (2011) PLoS ONE , vol.6
    • Li, H.1    Wang, H.2    Wang, F.3    Gu, Q.4    Xu, X.5
  • 24
    • 0030814347 scopus 로고    scopus 로고
    • Developmental changes in the subcellular localization of R-cadherin in chick retinal pigment epithelium
    • Liu X, Mizoguchi A, Takeichi M, Honda Y, Ide C. 1997. Developmental changes in the subcellular localization of R-cadherin in chick retinal pigment epithelium. Histochem Cell Biol 108:35-43.
    • (1997) Histochem Cell Biol , vol.108 , pp. 35-43
    • Liu, X.1    Mizoguchi, A.2    Takeichi, M.3    Honda, Y.4    Ide, C.5
  • 26
    • 77953588128 scopus 로고    scopus 로고
    • Zinc-finger transcription factor slug contributes to the survival advantage of chronic myeloid leukemia cells
    • Mancini M, Petta S, Iacobucci I, Salvestrini V, Barbieri E, Santucci MA. 2010. Zinc-finger transcription factor slug contributes to the survival advantage of chronic myeloid leukemia cells. Cell Signal 22:1247-1253.
    • (2010) Cell Signal , vol.22 , pp. 1247-1253
    • Mancini, M.1    Petta, S.2    Iacobucci, I.3    Salvestrini, V.4    Barbieri, E.5    Santucci, M.A.6
  • 28
    • 0342368864 scopus 로고
    • Embryology of the human retinal pigment epithelium.
    • Zinn KM, Marmor MF, editors. Cambridge, MA and London: Harvard University Press.
    • Mund ML, Rodrigues MM. 1979. Embryology of the human retinal pigment epithelium. In: Zinn KM, Marmor MF, editors. Cambridge, MA and London: Harvard University Press.
    • (1979)
    • Mund, M.L.1    Rodrigues, M.M.2
  • 29
    • 84863393338 scopus 로고    scopus 로고
    • Twist modulates human trophoblastic cell invasion via regulation of N-cadherin
    • Ng YH, Zhu H, Leung PC. 2012. Twist modulates human trophoblastic cell invasion via regulation of N-cadherin. Endocrinology 153:925-936.
    • (2012) Endocrinology , vol.153 , pp. 925-936
    • Ng, Y.H.1    Zhu, H.2    Leung, P.C.3
  • 30
    • 0036513626 scopus 로고    scopus 로고
    • The snail superfamily of zinc-finger transcription factors
    • Nieto MA. 2002. The snail superfamily of zinc-finger transcription factors. Nat Rev Mol Cell Biol 3:155-166.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 155-166
    • Nieto, M.A.1
  • 31
    • 80052712201 scopus 로고    scopus 로고
    • The ins and outs of the epithelial to mesenchymal transition in health and disease
    • Nieto MA. 2011. The ins and outs of the epithelial to mesenchymal transition in health and disease. Annu Rev Cell Dev Biol 27:347-376.
    • (2011) Annu Rev Cell Dev Biol , vol.27 , pp. 347-376
    • Nieto, M.A.1
  • 32
    • 79960270517 scopus 로고    scopus 로고
    • Evolution: Structural and functional diversity of cadherin at the adherens junction
    • Oda H, Takeichi M. 2011. Evolution: Structural and functional diversity of cadherin at the adherens junction. J Cell Biol 193:1137-1146.
    • (2011) J Cell Biol , vol.193 , pp. 1137-1146
    • Oda, H.1    Takeichi, M.2
  • 33
    • 2342431153 scopus 로고    scopus 로고
    • The transcription factor Snail downregulates the tight junction components independently of E-cadherin downregulation
    • Ohkubo T, Ozawa M. 2004. The transcription factor Snail downregulates the tight junction components independently of E-cadherin downregulation. J Cell Sci 117:1675-1685.
    • (2004) J Cell Sci , vol.117 , pp. 1675-1685
    • Ohkubo, T.1    Ozawa, M.2
  • 34
    • 0033545209 scopus 로고    scopus 로고
    • Integrin-dependent control of translation: Engagement of integrin alphaIIbbeta3 regulates synthesis of proteins in activated human platelets
    • Pabla R, Weyrich AS, Dixon DA, Bray PF, McIntyre TM, Prescott SM, Zimmerman GA. 1999. Integrin-dependent control of translation: Engagement of integrin alphaIIbbeta3 regulates synthesis of proteins in activated human platelets. J Cell Biol 144:175-184.
    • (1999) J Cell Biol , vol.144 , pp. 175-184
    • Pabla, R.1    Weyrich, A.S.2    Dixon, D.A.3    Bray, P.F.4    McIntyre, T.M.5    Prescott, S.M.6    Zimmerman, G.A.7
  • 35
    • 38949179153 scopus 로고    scopus 로고
    • The activation of MEK-ERK1/2 by glutamate receptor-stimulation is involved in the regulation of RPE proliferation and morphologic transformation
    • Pacheco-Dominguez RL, Palma-Nicolas JP, Lopez E, Lopez-Colome AM. 2008. The activation of MEK-ERK1/2 by glutamate receptor-stimulation is involved in the regulation of RPE proliferation and morphologic transformation. Exp Eye Res 86:207-219.
    • (2008) Exp Eye Res , vol.86 , pp. 207-219
    • Pacheco-Dominguez, R.L.1    Palma-Nicolas, J.P.2    Lopez, E.3    Lopez-Colome, A.M.4
  • 36
    • 59049093147 scopus 로고    scopus 로고
    • PKC isoenzymes differentially modulate the effect of thrombin on MAPK-dependent RPE proliferation
    • Palma-Nicolas JP, Lopez E, Lopez-Colome AM. 2008. PKC isoenzymes differentially modulate the effect of thrombin on MAPK-dependent RPE proliferation. Biosci Rep 28:307-317.
    • (2008) Biosci Rep , vol.28 , pp. 307-317
    • Palma-Nicolas, J.P.1    Lopez, E.2    Lopez-Colome, A.M.3
  • 37
    • 77954100130 scopus 로고    scopus 로고
    • Thrombin stimulates RPE cell motility by PKC-zeta- and NF-kappaB-dependent gene expression of MCP-1 and CINC-1/GRO chemokines
    • Palma-Nicolas JP, Lopez E, Lopez-Colome AM. 2010. Thrombin stimulates RPE cell motility by PKC-zeta- and NF-kappaB-dependent gene expression of MCP-1 and CINC-1/GRO chemokines. J Cell Biochem 110:948-967.
    • (2010) J Cell Biochem , vol.110 , pp. 948-967
    • Palma-Nicolas, J.P.1    Lopez, E.2    Lopez-Colome, A.M.3
  • 38
    • 73349095402 scopus 로고    scopus 로고
    • Thrombin stimulates RPE cell proliferation by promoting c-Fos-mediated cyclin D1 expression
    • Parrales A, Palma-Nicolas JP, Lopez E, Lopez-Colome AM. 2010. Thrombin stimulates RPE cell proliferation by promoting c-Fos-mediated cyclin D1 expression. J Cell Physiol 222:302-312.
    • (2010) J Cell Physiol , vol.222 , pp. 302-312
    • Parrales, A.1    Palma-Nicolas, J.P.2    Lopez, E.3    Lopez-Colome, A.M.4
  • 39
    • 34249289041 scopus 로고    scopus 로고
    • Snail, Zeb and bHLH factors in tumour progression: An alliance against the epithelial phenotype
    • Peinado H, Olmeda D, Cano A. 2007. Snail, Zeb and bHLH factors in tumour progression: An alliance against the epithelial phenotype? Nat Rev Cancer 7:415-428.
    • (2007) Nat Rev Cancer , vol.7 , pp. 415-428
    • Peinado, H.1    Olmeda, D.2    Cano, A.3
  • 40
    • 78649680349 scopus 로고    scopus 로고
    • Thrombin promotes actin stress fiber formation in RPE through Rho/ROCK-mediated MLC phosphorylation
    • Ruiz-Loredo AY, Lopez E, Lopez-Colome AM. 2011. Thrombin promotes actin stress fiber formation in RPE through Rho/ROCK-mediated MLC phosphorylation. J Cell Physiol 226:414-423.
    • (2011) J Cell Physiol , vol.226 , pp. 414-423
    • Ruiz-Loredo, A.Y.1    Lopez, E.2    Lopez-Colome, A.M.3
  • 41
    • 77951684623 scopus 로고    scopus 로고
    • Signal transduction by protease-activated receptors
    • Soh UJ, Dores MR, Chen B, Trejo J. 2010. Signal transduction by protease-activated receptors. Br J Pharmacol 160:191-203.
    • (2010) Br J Pharmacol , vol.160 , pp. 191-203
    • Soh, U.J.1    Dores, M.R.2    Chen, B.3    Trejo, J.4
  • 43
    • 81855169682 scopus 로고    scopus 로고
    • Mammalian TOR signaling to the AGC kinases
    • Su B, Jacinto E. 2011. Mammalian TOR signaling to the AGC kinases. Crit Rev Biochem Mol Biol 46:527-547.
    • (2011) Crit Rev Biochem Mol Biol , vol.46 , pp. 527-547
    • Su, B.1    Jacinto, E.2
  • 44
    • 16844362466 scopus 로고    scopus 로고
    • Synaptic contact dynamics controlled by cadherin and catenins
    • Takeichi M, Abe K. 2005. Synaptic contact dynamics controlled by cadherin and catenins. Trends Cell Biol 15:216-221.
    • (2005) Trends Cell Biol , vol.15 , pp. 216-221
    • Takeichi, M.1    Abe, K.2
  • 45
    • 77952495532 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition and proliferation of retinal pigment epithelial cells initiated upon loss of cell-cell contact
    • Tamiya S, Liu L, Kaplan HJ. 2010. Epithelial-mesenchymal transition and proliferation of retinal pigment epithelial cells initiated upon loss of cell-cell contact. Invest Ophthalmol Vis Sci 51:2755-2763.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 2755-2763
    • Tamiya, S.1    Liu, L.2    Kaplan, H.J.3
  • 46
    • 55749101603 scopus 로고    scopus 로고
    • New insights into cadherin function in epidermal sheet formation and maintenance of tissue integrity
    • Tinkle CL, Pasolli HA, Stokes N, Fuchs E. 2008. New insights into cadherin function in epidermal sheet formation and maintenance of tissue integrity. Proc Natl Acad Sci USA 105:15405-15410.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 15405-15410
    • Tinkle, C.L.1    Pasolli, H.A.2    Stokes, N.3    Fuchs, E.4
  • 47
    • 14644437760 scopus 로고    scopus 로고
    • Negative regulation of the expressions of cytokeratins 8 and 19 by SLUG repressor protein in human breast cells
    • Tripathi MK, Misra S, Chaudhuri G. 2005. Negative regulation of the expressions of cytokeratins 8 and 19 by SLUG repressor protein in human breast cells. Biochem Biophys Res Commun 329:508-515.
    • (2005) Biochem Biophys Res Commun , vol.329 , pp. 508-515
    • Tripathi, M.K.1    Misra, S.2    Chaudhuri, G.3
  • 49
    • 33746402845 scopus 로고    scopus 로고
    • Bone morphogenetic protein-4 enhances vascular endothelial growth factor secretion by human retinal pigment epithelial cells
    • Vogt RR, Unda R, Yeh LC, Vidro EK, Lee JC, Tsin AT. 2006. Bone morphogenetic protein-4 enhances vascular endothelial growth factor secretion by human retinal pigment epithelial cells. J Cell Biochem 98:1196-1202.
    • (2006) J Cell Biochem , vol.98 , pp. 1196-1202
    • Vogt, R.R.1    Unda, R.2    Yeh, L.C.3    Vidro, E.K.4    Lee, J.C.5    Tsin, A.T.6
  • 50
    • 80051637832 scopus 로고    scopus 로고
    • mTORC1 signaling: What we still don't know
    • Wang X, Proud CG. 2011. mTORC1 signaling: What we still don't know. J Mol Cell Biol 3:206-220.
    • (2011) J Mol Cell Biol , vol.3 , pp. 206-220
    • Wang, X.1    Proud, C.G.2
  • 52
    • 67650996754 scopus 로고    scopus 로고
    • Biomarkers for epithelial-mesenchymal transitions
    • Zeisberg M, Neilson EG. 2009. Biomarkers for epithelial-mesenchymal transitions. J Clin Invest 119:1429-1437.
    • (2009) J Clin Invest , vol.119 , pp. 1429-1437
    • Zeisberg, M.1    Neilson, E.G.2


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