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Volumn 6, Issue 4, 2011, Pages

Mature peripheral RPE cells have an intrinsic capacity to proliferate; a potential regulatory mechanism for age-related cell loss

Author keywords

[No Author keywords available]

Indexed keywords

F ACTIN; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN P27; PROTEIN ZO1; UVOMORULIN; ACTIN; BIOLOGICAL MARKER; MEMBRANE PROTEIN; PHOSPHOPROTEIN; ZONULA OCCLUDENS-1 PROTEIN;

EID: 79955545737     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0018921     Document Type: Article
Times cited : (49)

References (40)
  • 1
    • 0029410697 scopus 로고
    • The retinal pigmented epithelium is required for development and maintenance of the mouse neural retina
    • Raymond SM, Jackson IJ, (1995) The retinal pigmented epithelium is required for development and maintenance of the mouse neural retina. Curr Biol 5: 1286-1295.
    • (1995) Curr Biol , vol.5 , pp. 1286-1295
    • Raymond, S.M.1    Jackson, I.J.2
  • 2
    • 0022521537 scopus 로고
    • The natural history of serous retinal pigment epithelium detachment in patients with age-related macular degeneration
    • Elman MJ, Fine SL, Murphy RP, Patz A, Auer C, (1986) The natural history of serous retinal pigment epithelium detachment in patients with age-related macular degeneration. Ophthalmology 93: 224-230.
    • (1986) Ophthalmology , vol.93 , pp. 224-230
    • Elman, M.J.1    Fine, S.L.2    Murphy, R.P.3    Patz, A.4    Auer, C.5
  • 3
    • 0022496838 scopus 로고
    • A study of photoreceptor-retinal pigment epithelium complex: age-related changes in monkeys
    • Lai YL, Rana MW, (1986) A study of photoreceptor-retinal pigment epithelium complex: age-related changes in monkeys. Proc Soc Exp Biol Med 181: 371-381.
    • (1986) Proc Soc Exp Biol Med , vol.181 , pp. 371-381
    • Lai, Y.L.1    Rana, M.W.2
  • 4
    • 77958126469 scopus 로고    scopus 로고
    • Retinal pigment epithelium defects accelerate photoreceptor degeneration in cell type-specific knockout mouse models of choroideremia
    • Tolmachova T, Wavre-Shapton ST, Barnard AR, MacLaren RE, Futter CE, et al. (2010) Retinal pigment epithelium defects accelerate photoreceptor degeneration in cell type-specific knockout mouse models of choroideremia. Invest Ophthalmol Vis Sci 51: 4913-4920.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 4913-4920
    • Tolmachova, T.1    Wavre-Shapton, S.T.2    Barnard, A.R.3    MacLaren, R.E.4    Futter, C.E.5
  • 5
    • 0020958038 scopus 로고
    • The ninth Frederick H. Verhoeff lecture. The life history of retinal cells
    • Young RW, (1983) The ninth Frederick H. Verhoeff lecture. The life history of retinal cells. Trans Am Ophthalmol Soc 81: 193-228.
    • (1983) Trans Am Ophthalmol Soc , vol.81 , pp. 193-228
    • Young, R.W.1
  • 7
    • 0035025619 scopus 로고    scopus 로고
    • Direct neural fate specification from embryonic stem cells: a primitive mammalian neural stem cell stage acquired through a default mechanism
    • Tropepe V, Hitoshi S, Sirard C, Mak TW, Rossant J, et al. (2001) Direct neural fate specification from embryonic stem cells: a primitive mammalian neural stem cell stage acquired through a default mechanism. Neuron 30: 65-78.
    • (2001) Neuron , vol.30 , pp. 65-78
    • Tropepe, V.1    Hitoshi, S.2    Sirard, C.3    Mak, T.W.4    Rossant, J.5
  • 8
    • 77649184122 scopus 로고    scopus 로고
    • Held under arrest: Many mature albino RPE cells display polyploidal features consistent with abnormal cell cycle retention
    • Adams T, Shahabi G, Hoh-Kam J, Jeffery G, (2009) Held under arrest: Many mature albino RPE cells display polyploidal features consistent with abnormal cell cycle retention. Exp Eye Res 90: 368-372.
    • (2009) Exp Eye Res , vol.90 , pp. 368-372
    • Adams, T.1    Shahabi, G.2    Hoh-Kam, J.3    Jeffery, G.4
  • 9
    • 54449097645 scopus 로고    scopus 로고
    • Mature retinal pigment epithelium cells are retained in the cell cycle and proliferate in vivo
    • Al-Hussaini H, Kam JH, Vugler A, Semo M, Jeffery G, (2008) Mature retinal pigment epithelium cells are retained in the cell cycle and proliferate in vivo. Mol Vis 14: 1784-1791.
    • (2008) Mol Vis , vol.14 , pp. 1784-1791
    • Al-Hussaini, H.1    Kam, J.H.2    Vugler, A.3    Semo, M.4    Jeffery, G.5
  • 10
    • 0035670438 scopus 로고    scopus 로고
    • Transdifferentiation of pigmented epithelial cells: a source of retinal stem cells?
    • Fischer AJ, Reh TA, (2001) Transdifferentiation of pigmented epithelial cells: a source of retinal stem cells? Dev Neurosci 23: 268-276.
    • (2001) Dev Neurosci , vol.23 , pp. 268-276
    • Fischer, A.J.1    Reh, T.A.2
  • 11
    • 0034738146 scopus 로고    scopus 로고
    • The subcellular localization of Otx2 is cell-type specific and developmentally regulated in the mouse retina
    • Baas D, Bumsted KM, Martinez JA, Vaccarino FM, Wikler KC, et al. (2000) The subcellular localization of Otx2 is cell-type specific and developmentally regulated in the mouse retina. Brain Res Mol Brain Res 78: 26-37.
    • (2000) Brain Res Mol Brain Res , vol.78 , pp. 26-37
    • Baas, D.1    Bumsted, K.M.2    Martinez, J.A.3    Vaccarino, F.M.4    Wikler, K.C.5
  • 13
    • 1542347695 scopus 로고    scopus 로고
    • Convergence of Wnt, beta-catenin, and cadherin pathways
    • Nelson WJ, Nusse R, (2004) Convergence of Wnt, beta-catenin, and cadherin pathways. Science 303: 1483-1487.
    • (2004) Science , vol.303 , pp. 1483-1487
    • Nelson, W.J.1    Nusse, R.2
  • 15
    • 33847307720 scopus 로고    scopus 로고
    • Defects in retinal pigment epithelium cell proliferation and retinal attachment in mutant mice with p27(Kip1) gene ablation
    • Defoe DM, Adams LB, Sun J, Wisecarver SN, Levine EM, (2007) Defects in retinal pigment epithelium cell proliferation and retinal attachment in mutant mice with p27(Kip1) gene ablation. Mol Vis 13: 273-286.
    • (2007) Mol Vis , vol.13 , pp. 273-286
    • Defoe, D.M.1    Adams, L.B.2    Sun, J.3    Wisecarver, S.N.4    Levine, E.M.5
  • 16
    • 2942598345 scopus 로고    scopus 로고
    • Involvement of p27(KIP1) in proliferation of the retinal pigment epithelium and ciliary body
    • Yoshida K, Nakayama K, Kase S, Nagahama H, Harada T, et al. (2004) Involvement of p27(KIP1) in proliferation of the retinal pigment epithelium and ciliary body. Anat Embryol (Berl) 208: 145-150.
    • (2004) Anat Embryol (Berl) , vol.208 , pp. 145-150
    • Yoshida, K.1    Nakayama, K.2    Kase, S.3    Nagahama, H.4    Harada, T.5
  • 17
    • 73349095402 scopus 로고    scopus 로고
    • Thrombin stimulates RPE cell proliferation by promoting c-Fos-mediated cyclin D1 expression
    • Parrales A, Palma-Nicolas JP, Lopez E, Lopez-Colome AM, (2010) Thrombin stimulates RPE cell proliferation by promoting c-Fos-mediated cyclin D1 expression. J Cell Physiol 222: 302-312.
    • (2010) J Cell Physiol , vol.222 , pp. 302-312
    • Parrales, A.1    Palma-Nicolas, J.P.2    Lopez, E.3    Lopez-Colome, A.M.4
  • 18
    • 79952116991 scopus 로고    scopus 로고
    • TP53 and MTOR crosstalk to regulate cellular senescence
    • Galluzzi L, Kepp O, Kroemer G, (2010) TP53 and MTOR crosstalk to regulate cellular senescence. Aging (Albany NY) 2: 535-537.
    • (2010) Aging (Albany NY) , vol.2 , pp. 535-537
    • Galluzzi, L.1    Kepp, O.2    Kroemer, G.3
  • 20
    • 59449099708 scopus 로고    scopus 로고
    • Subtoxic oxidative stress induces senescence in retinal pigment epithelial cells via TGF-beta release
    • Yu AL, Fuchshofer R, Kook D, Kampik A, Bloemendal H, et al. (2009) Subtoxic oxidative stress induces senescence in retinal pigment epithelial cells via TGF-beta release. Invest Ophthalmol Vis Sci 50: 926-935.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 926-935
    • Yu, A.L.1    Fuchshofer, R.2    Kook, D.3    Kampik, A.4    Bloemendal, H.5
  • 22
    • 78651238212 scopus 로고    scopus 로고
    • The tight junction associated signalling proteins ZO-1 and ZONAB regulate retinal pigment epithelium homeostasis in mice
    • Georgiadis A, Tschernutter M, Bainbridge JW, Balaggan KS, Mowat F, et al. (2010) The tight junction associated signalling proteins ZO-1 and ZONAB regulate retinal pigment epithelium homeostasis in mice. PLoS ONE 5: e15730.
    • (2010) PLoS ONE , vol.5 , pp. 15730
    • Georgiadis, A.1    Tschernutter, M.2    Bainbridge, J.W.3    Balaggan, K.S.4    Mowat, F.5
  • 23
    • 0029066035 scopus 로고
    • Development of the blood-retinal barrier in vitro: formation of tight junctions as revealed by occludin and ZO-1 correlates with the barrier function of chick retinal pigment epithelial cells
    • Konari K, Sawada N, Zhong Y, Isomura H, Nakagawa T, et al. (1995) Development of the blood-retinal barrier in vitro: formation of tight junctions as revealed by occludin and ZO-1 correlates with the barrier function of chick retinal pigment epithelial cells. Exp Eye Res 61: 99-108.
    • (1995) Exp Eye Res , vol.61 , pp. 99-108
    • Konari, K.1    Sawada, N.2    Zhong, Y.3    Isomura, H.4    Nakagawa, T.5
  • 24
    • 0037415643 scopus 로고    scopus 로고
    • The ZO-1-associated Y-box factor ZONAB regulates epithelial cell proliferation and cell density
    • Balda MS, Garrett MD, Matter K, (2003) The ZO-1-associated Y-box factor ZONAB regulates epithelial cell proliferation and cell density. J Cell Biol 160: 423-432.
    • (2003) J Cell Biol , vol.160 , pp. 423-432
    • Balda, M.S.1    Garrett, M.D.2    Matter, K.3
  • 25
    • 0036785896 scopus 로고    scopus 로고
    • Age-related changes in human RPE cell density and apoptosis proportion in situ
    • Del Priore LV, Kuo YH, Tezel TH, (2002) Age-related changes in human RPE cell density and apoptosis proportion in situ. Invest Ophthalmol Vis Sci 43: 3312-3318.
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 3312-3318
    • Del Priore, L.V.1    Kuo, Y.H.2    Tezel, T.H.3
  • 26
    • 3242721268 scopus 로고    scopus 로고
    • mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells
    • Murakami M, Ichisaka T, Maeda M, Oshiro N, Hara K, et al. (2004) mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells. Mol Cell Biol 24: 6710-6718.
    • (2004) Mol Cell Biol , vol.24 , pp. 6710-6718
    • Murakami, M.1    Ichisaka, T.2    Maeda, M.3    Oshiro, N.4    Hara, K.5
  • 27
    • 0036225314 scopus 로고    scopus 로고
    • Dapper, a Dishevelled-associated antagonist of beta-catenin and JNK signaling, is required for notochord formation
    • Cheyette BN, Waxman JS, Miller JR, Takemaru K, Sheldahl LC, et al. (2002) Dapper, a Dishevelled-associated antagonist of beta-catenin and JNK signaling, is required for notochord formation. Dev Cell 2: 449-461.
    • (2002) Dev Cell , vol.2 , pp. 449-461
    • Cheyette, B.N.1    Waxman, J.S.2    Miller, J.R.3    Takemaru, K.4    Sheldahl, L.C.5
  • 29
    • 0036349776 scopus 로고    scopus 로고
    • Systematic analysis of E-, N- and P-cadherin expression in mouse eye development
    • Xu L, Overbeek PA, Reneker LW, (2002) Systematic analysis of E-, N- and P-cadherin expression in mouse eye development. Exp Eye Res 74: 753-760.
    • (2002) Exp Eye Res , vol.74 , pp. 753-760
    • Xu, L.1    Overbeek, P.A.2    Reneker, L.W.3
  • 30
    • 0032759730 scopus 로고    scopus 로고
    • Expression of E-cadherin by human retinal pigment epithelium: delayed expression in vitro
    • Burke JM, Cao F, Irving PE, Skumatz CM, (1999) Expression of E-cadherin by human retinal pigment epithelium: delayed expression in vitro. Invest Ophthalmol Vis Sci 40: 2963-2970.
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , pp. 2963-2970
    • Burke, J.M.1    Cao, F.2    Irving, P.E.3    Skumatz, C.M.4
  • 31
    • 0014477738 scopus 로고
    • Development of the human retinal pigment epithelium and the posterior segment
    • Streeten BW, (1969) Development of the human retinal pigment epithelium and the posterior segment. Arch Ophthalmol 81: 383-394.
    • (1969) Arch Ophthalmol , vol.81 , pp. 383-394
    • Streeten, B.W.1
  • 32
    • 56749184887 scopus 로고    scopus 로고
    • Tight junction-based epithelial microenvironment and cell proliferation
    • Tsukita S, Yamazaki Y, Katsuno T, Tamura A, (2008) Tight junction-based epithelial microenvironment and cell proliferation. Oncogene 27: 6930-6938.
    • (2008) Oncogene , vol.27 , pp. 6930-6938
    • Tsukita, S.1    Yamazaki, Y.2    Katsuno, T.3    Tamura, A.4
  • 33
    • 24644496823 scopus 로고    scopus 로고
    • Mammalian tight junctions in the regulation of epithelial differentiation and proliferation
    • Matter K, Aijaz S, Tsapara A, Balda MS, (2005) Mammalian tight junctions in the regulation of epithelial differentiation and proliferation. Curr Opin Cell Biol 17: 453-458.
    • (2005) Curr Opin Cell Biol , vol.17 , pp. 453-458
    • Matter, K.1    Aijaz, S.2    Tsapara, A.3    Balda, M.S.4
  • 34
    • 78651286218 scopus 로고    scopus 로고
    • Intestinal epithelial cell proliferation, apoptosis and expression of tight junction proteins in patients with obstructive jaundice
    • Assimakopoulos SF, Tsamandas AC, Louvros E, Vagianos CE, Nikolopoulou VN, et al. (2011) Intestinal epithelial cell proliferation, apoptosis and expression of tight junction proteins in patients with obstructive jaundice. Eur J Clin Invest 41: 117-125.
    • (2011) Eur J Clin Invest , vol.41 , pp. 117-125
    • Assimakopoulos, S.F.1    Tsamandas, A.C.2    Louvros, E.3    Vagianos, C.E.4    Nikolopoulou, V.N.5
  • 35
    • 11144330946 scopus 로고    scopus 로고
    • IGF-1 produced by cone photoreceptors regulates rod progenitor proliferation in the teleost retina
    • Zygar CA, Colbert S, Yang D, Fernald RD, (2005) IGF-1 produced by cone photoreceptors regulates rod progenitor proliferation in the teleost retina. Brain Res Dev Brain Res 154: 91-100.
    • (2005) Brain Res Dev Brain Res , vol.154 , pp. 91-100
    • Zygar, C.A.1    Colbert, S.2    Yang, D.3    Fernald, R.D.4
  • 37
    • 33846909313 scopus 로고    scopus 로고
    • Subretinal posterior pole injury induces selective proliferation of RPE cells in the periphery in in vivo studies in pigs
    • Kiilgaard JF, Prause JU, Prause M, Scherfig E, Nissen MH, et al. (2007) Subretinal posterior pole injury induces selective proliferation of RPE cells in the periphery in in vivo studies in pigs. Invest Ophthalmol Vis Sci 48: 355-360.
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 355-360
    • Kiilgaard, J.F.1    Prause, J.U.2    Prause, M.3    Scherfig, E.4    Nissen, M.H.5
  • 38
    • 77952302731 scopus 로고    scopus 로고
    • Microscopic mammalian retinal pigment epithelium lesions induce widespread proliferation with differences in magnitude between center and periphery
    • von Leithner PL, Ciurtin C, Jeffery G, (2010) Microscopic mammalian retinal pigment epithelium lesions induce widespread proliferation with differences in magnitude between center and periphery. Mol Vis 16: 570-581.
    • (2010) Mol Vis , vol.16 , pp. 570-581
    • von Leithner, P.L.1    Ciurtin, C.2    Jeffery, G.3
  • 39
    • 33644850129 scopus 로고    scopus 로고
    • Visual cycle protein RPE65 persists in new retinal cells during retinal regeneration of adult newt
    • Chiba C, Hoshino A, Nakamura K, Susaki K, Yamano Y, et al. (2006) Visual cycle protein RPE65 persists in new retinal cells during retinal regeneration of adult newt. J Comp Neurol 495: 391-407.
    • (2006) J Comp Neurol , vol.495 , pp. 391-407
    • Chiba, C.1    Hoshino, A.2    Nakamura, K.3    Susaki, K.4    Yamano, Y.5


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