Stress-induced cartilage degradation does not depend on the NLRP3 inflammasome in human osteoarthritis and mouse models

Arthritis and Rheumatism

Volumn 64, Issue 12, 2012, Pages 3972-3981

  Bougault, Carole ^a   Gosset, Marjolaine ^a   Houard, Xavier ^a   Salvat, Colette ^a   Godmann, Lars ^b   Pap, Thomas ^b   Jacques, Claire ^a   Berenbaum, Francis ^c  

^a SORBONNE UNIVERSITÉ   (France)

^b UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^c HÔPITAL SAINT ANTOINE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AGGRECANASE 1; AGGRECANASE 2; COLLAGENASE 3; CRYOPYRIN; GELATINASE A; GELATINASE B; GLYCOSAMINOGLYCAN; INFLAMMASOME; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 18; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LIPOPOLYSACCHARIDE; MESSENGER RNA; STROMELYSIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARTILAGE CELL; CARTILAGE DEGENERATION; CELL VIABILITY; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DOSE RESPONSE; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN TISSUE; KNEE OSTEOARTHRITIS; MECHANICAL STRESS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ANIMALS; CARRIER PROTEINS; CARTILAGE, ARTICULAR; CASPASE 1; CELLS, CULTURED; CHONDROCYTES; DISEASE MODELS, ANIMAL; HUMANS; INFLAMMASOMES; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MATRIX METALLOPROTEINASES; MICE; MICE, KNOCKOUT; OSTEOARTHRITIS, KNEE; STRESS, MECHANICAL; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84870360269     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.34678     Document Type: Article

References (52)

1. Zhang Y, Jordan JM,. Epidemiology of osteoarthritis. Clin Geriatr Med 2010; 26: 355-69.
2. Martel-Pelletier J, Pelletier JP,. Is osteoarthritis a disease involving only cartilage or other articular tissues? Eklem Hastalik Cerrahisi 2010; 21: 2-14.
3. Goldring MB, Goldring SR,. Osteoarthritis. J Cell Physiol 2007; 213: 626-34. (Pubitemid 350058254)
4. Murphy G, Nagase H,. Reappraising metalloproteinases in rheumatoid arthritis and osteoarthritis: destruction or repair? Nat Clin Pract Rheumatol 2008; 4: 128-35. (Pubitemid 351338627)
5. Yoshida M, Tsuji M, Funasaki H, Kan I, Fujii K,. Analysis for the major contributor of collagenase to the primary cleavage of type II collagens in cartilage degradation. Mod Rheumatol 2005; 15: 180-6. (Pubitemid 40983485)
6. Jacques C, Gosset M, Berenbaum F, Gabay C,. The role of IL-1 and IL-1Ra in joint inflammation and cartilage degradation. Vitam Horm 2006; 74: 371-403.
7. Kapoor M, Martel-Pelletier J, Lajeunesse D, Pelletier JP, Fahmi H,. Role of proinflammatory cytokines in the pathophysiology of osteoarthritis. Nat Rev Rheumatol 2011; 7: 33-42.
8. Bauernfeind F, Ablasser A, Bartok E, Kim S, Schmid-Burgk J, Cavlar T, et al. Inflammasomes: current understanding and open questions. Cell Mol Life Sci 2011; 68: 765-83.
9. Schroder K, Tschopp J,. The inflammasomes. Cell 2010; 140: 821-32.
10. Davis BK, Wen H, Ting JP,. The inflammasome NLRs in immunity, inflammation, and associated diseases. Annu Rev Immunol 2011; 29: 707-35.
11. Schroder K, Zhou R, Tschopp J,. The NLRP3 inflammasome: a sensor for metabolic danger? Science 2010; 327: 296-300.
12. Bryant C, Fitzgerald KA,. Molecular mechanisms involved in inflammasome activation. Trends Cell Biol 2009; 19: 455-64.
13. Stehlik C,. Multiple interleukin-1β-converting enzymes contribute to inflammatory arthritis [editorial]. Arthritis Rheum 2009; 60: 3524-30.
14. Schonbeck U, Mach F, Libby P,. Generation of biologically active IL-1β by matrix metalloproteinases: a novel caspase-1-independent pathway of IL-1β processing. J Immunol 1998; 161: 3340-6.
15. Altman R, Asch E, Bloch D, Bole G, Borenstein D, Brandt K, et al. Development of criteria for the classification and reporting of osteoarthritis: classification of osteoarthritis of the knee. Arthritis Rheum 1986; 29: 1039-49.
16. Martinon F, Petrilli V, Mayor A, Tardivel A, Tschopp J,. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 2006; 440: 237-41. (Pubitemid 43372104)
17. Gosset M, Pigenet A, Salvat C, Berenbaum F, Jacques C,. Inhibition of matrix metalloproteinase-3 and -13 synthesis induced by IL-1β in chondrocytes from mice lacking microsomal prostaglandin E synthase-1. J Immunol 2010; 185: 6244-52.
18. Gosset M, Berenbaum F, Thirion S, Jacques C,. Primary culture and phenotyping of murine chondrocytes. Nat Protoc 2008; 3: 1253-60.
19. Gosset M, Berenbaum F, Levy A, Pigenet A, Thirion S, Saffar JL, et al. Prostaglandin E2 synthesis in cartilage explants under compression: mPGES-1 is a mechanosensitive gene. Arthritis Res Ther 2006; 8: R135.
20. Masuko-Hongo K, Berenbaum F, Humbert L, Salvat C, Goldring MB, Thirion S,. Up-regulation of microsomal prostaglandin E synthase 1 in osteoarthritic human cartilage: critical roles of the ERK-1/2 and p38 signaling pathways. Arthritis Rheum 2004; 50: 2829-38. (Pubitemid 39209520)
21. Houard X, Monnot C, Dive V, Corvol P, Pagano M,. Vascular smooth muscle cells efficiently activate a new proteinase cascade involving plasminogen and fibronectin. J Cell Biochem 2003; 88: 1188-201. (Pubitemid 36397457)
22. Farndale RW, Sayers CA, Barrett AJ,. A direct spectrophotometric microassay for sulfated glycosaminoglycans in cartilage cultures. Connect Tissue Res 1982; 9: 247-8. (Pubitemid 12009669)
23. Lo MY, Kim HT,. Chondrocyte apoptosis induced by hydrogen peroxide requires caspase activation but not mitochondrial pore transition. J Orthop Res 2004; 22: 1120-5. (Pubitemid 39145132)
24. Westacott CI, Whicher JT, Barnes IC, Thompson D, Swan AJ, Dieppe PA,. Synovial fluid concentration of five different cytokines in rheumatic diseases. Ann Rheum Dis 1990; 49: 676-81. (Pubitemid 20279117)
25. Denoble AE, Huffman KM, Stabler TV, Kelly SJ, Hershfield MS, McDaniel GE, et al. Uric acid is a danger signal of increasing risk for osteoarthritis through inflammasome activation. Proc Natl Acad Sci U S A 2011; 108: 2088-93.
26. Bertazzolo N, Punzi L, Stefani MP, Cesaro G, Pianon M, Finco B, et al. Interrelationships between interleukin (IL)-1, IL-6 and IL-8 in synovial fluid of various arthropathies. Agents Actions 1994; 41: 90-2. (Pubitemid 24121244)
27. Fan Z, Soder S, Oehler S, Fundel K, Aigner T,. Activation of interleukin-1 signaling cascades in normal and osteoarthritic articular cartilage. Am J Pathol 2007; 171: 938-46. (Pubitemid 47440992)
28. Moldovan F, Pelletier JP, Jolicoeur FC, Cloutier JM, Martel-Pelletier J,. Diacerhein and rhein reduce the ICE-induced IL-1β and IL-18 activation in human osteoarthritic cartilage. Osteoarthritis Cartilage 2000; 8: 186-96. (Pubitemid 30304186)
29. Saha N, Moldovan F, Tardif G, Pelletier JP, Cloutier JM, Martel-Pelletier J,. Interleukin-1β-converting enzyme/caspase-1 in human osteoarthritic tissues: localization and role in the maturation of interleukin-1β and interleukin-18. Arthritis Rheum 1999; 42: 1577-87. (Pubitemid 30263623)
30. Campo GM, Avenoso A, Campo S, D'Ascola A, Traina P, Sama D, et al. Purified human plasma glycosaminoglycans reduced NF-κB activation, pro-inflammatory cytokine production and apoptosis in LPS-treated chondrocytes. Innate Immun 2008; 14: 233-46.
31. 2 production by human chondrocytes. Osteoarthritis Cartilage 2002; 10: 547-55. (Pubitemid 34919070)
32. Olee T, Hashimoto S, Quach J, Lotz M,. IL-18 is produced by articular chondrocytes and induces proinflammatory and catabolic responses. J Immunol 1999; 162: 1096-100. (Pubitemid 29035439)
33. McCall SH, Sahraei M, Young AB, Worley CS, Duncan JA, Ting JP, et al. Osteoblasts express NLRP3, a nucleotide-binding domain and leucine-rich repeat region containing receptor implicated in bacterially induced cell death. J Bone Miner Res 2008; 23: 30-40.
34. Kolly L, Busso N, Palmer G, Talabot-Ayer D, Chobaz V, So A,. Expression and function of the NALP3 inflammasome in rheumatoid synovium. Immunology 2010; 129: 178-85.
35. Kolly L, Karababa M, Joosten LA, Narayan S, Salvi R, Petrilli V, et al. Inflammatory role of ASC in antigen-induced arthritis is independent of caspase-1, NALP-3, and IPAF. J Immunol 2009; 183: 4003-12.
36. Rosengren S, Hoffman HM, Bugbee W, Boyle DL,. Expression and regulation of cryopyrin and related proteins in rheumatoid arthritis synovium. Ann Rheum Dis 2005; 64: 708-14. (Pubitemid 40559297)
37. Tetlow LC, Adlam DJ, Woolley DE,. Matrix metalloproteinase and proinflammatory cytokine production by chondrocytes of human osteoarthritic cartilage: associations with degenerative changes. Arthritis Rheum 2001; 44: 585-94. (Pubitemid 32234617)
38. Gracie JA, Forsey RJ, Chan WL, Gilmour A, Leung BP, Greer MR, et al. A proinflammatory role for IL-18 in rheumatoid arthritis. J Clin Invest 1999; 104: 1393-401.
39. Smith MD, Triantafillou S, Parker A, Youssef PP, Coleman M,. Synovial membrane inflammation and cytokine production in patients with early osteoarthritis. J Rheumatol 1997; 24: 365-71. (Pubitemid 27104104)
40. Sellam J, Berenbaum F,. The role of synovitis in pathophysiology and clinical symptoms of osteoarthritis. Nat Rev Rheumatol 2010; 6: 625-35.
41. Kingsbury SR, Conaghan PG, McDermott MF,. The role of the NLRP3 inflammasome in gout. J Inflamm Res 2011; 4: 39-49.
42. Jin C, Frayssinet P, Pelker R, Cwirka D, Hu B, Vignery A, et al. NLRP3 inflammasome plays a critical role in the pathogenesis of hydroxyapatite- associated arthropathy. Proc Natl Acad Sci U S A 2011; 108: 14867-72.
43. Ippagunta SK, Brand DD, Luo J, Boyd KL, Calabrese C, Stienstra R, et al. Inflammasome-independent role of apoptosis-associated speck-like protein containing a CARD (ASC) in T cell priming is critical for collagen-induced arthritis. J Biol Chem 2010; 285: 12454-62.
44. D'Lima D, Hermida J, Hashimoto S, Colwell C, Lotz M,. Caspase inhibitors reduce severity of cartilage lesions in experimental osteoarthritis. Arthritis Rheum 2006; 54: 1814-21. (Pubitemid 43877931)
45. Rudolphi K, Gerwin N, Verzijl N, van der Kraan P, van den Berg W,. Pralnacasan, an inhibitor of interleukin-1β converting enzyme, reduces joint damage in two murine models of osteoarthritis. Osteoarthritis Cartilage 2003; 11: 738-46. (Pubitemid 37184492)
46. Kadri A, Ea HK, Bazille C, Hannouche D, Liote F, Cohen-Solal ME,. Osteoprotegerin inhibits cartilage degradation through an effect on trabecular bone in murine experimental osteoarthritis. Arthritis Rheum 2008; 58: 2379-86.
47. Chevalier X, Goupille P, Beaulieu AD, Burch FX, Bensen WG, Conrozier T, et al. Intraarticular injection of anakinra in osteoarthritis of the knee: a multicenter, randomized, double-blind, placebo-controlled study. Arthritis Rheum 2009; 61: 344-52.
48. Richette P, Francois M, Vicaut E, Fitting C, Bardin T, Corvol M, et al. A high interleukin 1 receptor antagonist/IL-1β ratio occurs naturally in knee osteoarthritis. J Rheumatol 2008; 35: 1650-4.
49. Santangelo KS, Pieczarka EM, Nuovo GJ, Weisbrode SE, Bertone AL,. Temporal expression and tissue distribution of interleukin-1β in two strains of guinea pigs with varying propensity for spontaneous knee osteoarthritis. Osteoarthritis Cartilage 2011; 19: 439-48.
50. Fan Z, Bau B, Yang H, Soeder S, Aigner T,. Freshly isolated osteoarthritic chondrocytes are catabolically more active than normal chondrocytes, but less responsive to catabolic stimulation with interleukin-1β. Arthritis Rheum 2005; 52: 136-43. (Pubitemid 40129242)
51. Barakat AF, Elson CJ, Westacott CI,. Susceptibility to physiological concentrations of IL-1β varies in cartilage at different anatomical locations on human osteoarthritic knee joints. Osteoarthritis Cartilage 2002; 10: 264-9. (Pubitemid 34467629)
52. Martel-Pelletier J, McCollum R, DiBattista J, Faure MP, Chin JA, Fournier S, et al. The interleukin-1 receptor in normal and osteoarthritic human articular chondrocytes: identification as the type I receptor and analysis of binding kinetics and biologic function. Arthritis Rheum 1992; 35: 530-40.