Nanog reverses the effects of organismal aging on mesenchymal stem cell proliferation and myogenic differentiation potential

Stem Cells

Volumn 30, Issue 12, 2012, Pages 2746-2759

  Han, Juhee ^a   Mistriotis, Panagiotis ^a   Lei, Pedro ^a   Wang, Dan ^b   Liu, Song ^b   Andreadis, Stelios T ^a,c,d  

^a the State University of New York   (United States)

^b ROSWELL PARK CANCER INSTITUTE   (United States)

^c University at Buffalo The State University of New York   (United States)

^d UNIVERSITY AT BUFFALO   (United States)

Author keywords

Aging; Cardiovascular regeneration; Contractility; Mesenchymal stem cells; Nanog; Smooth muscle

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BETA ACTIN; CALPONIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; OCTAMER TRANSCRIPTION FACTOR 4; SMAD PROTEIN; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; TRANSFORMING GROWTH FACTOR BETA;

AGED; AGING; ANIMAL CELL; ARTICLE; CELL CYCLE REGULATION; CELL PROLIFERATION; CELL THERAPY; CLONOGENESIS; CONTROLLED STUDY; DNA REPAIR; DNA REPLICATION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MALE; MESENCHYMAL STEM CELL; MICROARRAY ANALYSIS; MUSCLE CONTRACTILITY; MUSCLE DEVELOPMENT; NEWBORN; NONHUMAN; PLURIPOTENT STEM CELL; PROTEIN EXPRESSION; SENESCENCE; SHEEP; SIGNAL TRANSDUCTION; TISSUE REGENERATION; UPREGULATION;

ADULT; AGED; ANIMALS; ANIMALS, NEWBORN; BONE MARROW CELLS; CELL AGING; CELL CYCLE; CELL DIFFERENTIATION; CELL GROWTH PROCESSES; FEMALE; HOMEODOMAIN PROTEINS; HUMANS; MALE; MESENCHYMAL STROMAL CELLS; MICROARRAY ANALYSIS; MUSCLE, SMOOTH, VASCULAR; MUSCLES; SHEEP; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANSCRIPTOME; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION; YOUNG ADULT;

EID: 84870334911     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.1223     Document Type: Article

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