HSP90α deficiency does not affect immunoglobulin gene hypermutation and class switch but causes enhanced MHC class II antigen presentation

International Immunology

Volumn 24, Issue 12, 2012, Pages 751-758

  Li, Yingqian ^a   Li, Shuyin ^b   Hoshino, Mari ^c   Ishikawa, Rikiya ^c   Kajiwara, Chiaki ^c   Gao, Xiang ^a   Zhao, Yaofeng ^b   Ishido, Satoshi ^c   Udono, Heiichiro ^c   Wang, Ji Yang ^c  

^a MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^b CHINA AGRICULTURAL UNIVERSITY   (China)

^c RIKEN Center for Integrative Medical Sciences   (Japan)

Author keywords

Antigen presentation; Class switch recombination; Heat shock protein 90; Humoral immune response; IG gene hypermutation

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; HEAT SHOCK PROTEIN 90; IMMUNOGLOBULIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ANTIGEN PRESENTATION; ARTICLE; B LYMPHOCYTE; CELL MATURATION; CELLULAR IMMUNITY; CONTROLLED STUDY; CROSS PRESENTATION; DENDRITIC CELL; GENE FREQUENCY; GENE MUTATION; GENE REARRANGEMENT; HELPER CELL; HUMORAL IMMUNITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE;

ANIMALS; ANTIGEN PRESENTATION; ANTIGENS; B-LYMPHOCYTES; CYTIDINE DEAMINASE; HISTOCOMPATIBILITY ANTIGENS CLASS II; HSP90 HEAT-SHOCK PROTEINS; HUMANS; HYBRIDOMAS; IMMUNITY, HUMORAL; IMMUNOGLOBULIN CLASS SWITCHING; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTEIN ISOFORMS; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 84870310808     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxs076     Document Type: Article

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