RNAi screen in apoptotic cancer cell-stimulated human macrophages reveals co-regulation of IL-6/IL-10 expression

Immunobiology

Volumn 218, Issue 1, 2013, Pages 40-51

  Ley, Stephanie ^a   Weigert, Andreas ^a   Hériché, Jean Karim ^b   Mille Baker, Blandine ^c   Janssen, Richard A J ^d   Brüne, Bernhard ^a  

^a GOETHE UNIVERSITY   (Germany)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^c BioFocus DPI   (United Kingdom)

^d Galapagos BV   (Netherlands)

Author keywords

Apoptosis; CB2; IL4RA; Inflammation; Interleukin 10

Indexed keywords

ADENOVIRUS VECTOR; CANNABINOID 2 RECEPTOR; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 4 RECEPTOR ALPHA; INTERLEUKIN 6; INTERLEUKIN 8; SHORT HAIRPIN RNA;

APOPTOSIS; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; GENE TARGETING; GENETIC TRANSFECTION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; LEUKOCYTE FUNCTION; MACROPHAGE ACTIVATION; MONOCYTE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SUPERNATANT; TUMOR ASSOCIATED LEUKOCYTE;

ADENOVIRIDAE; ANTIGENS, NEOPLASM; CELLS, CULTURED; GENE EXPRESSION REGULATION, NEOPLASTIC; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; INTERLEUKIN-10; INTERLEUKIN-6; MACROPHAGES; MOLECULAR TARGETED THERAPY; NEOPLASMS; PRIMARY CELL CULTURE; RECEPTOR, CANNABINOID, CB2; RECEPTORS, CELL SURFACE; RNA, SMALL INTERFERING; TUMOR ESCAPE; TUMOR MICROENVIRONMENT;

EID: 84870291109     PISSN: 01712985     EISSN: 18783279     Source Type: Journal    
DOI: 10.1016/j.imbio.2012.01.019     Document Type: Article

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