Sophoridine exerts an anti-colorectal carcinoma effect through apoptosis induction in vitro and in vivo

Life Sciences

Volumn 91, Issue 25-26, 2012, Pages 1295-1303

  Liang, Lei ^a   Wang, Xiao Yan ^b   Zhang, Xu Hui ^c   Ji, Bo ^a   Yan, Hua Cheng ^a   Deng, Hong Zhu ^b   Wu, Xin Rong ^a  

^a GUANGZHOU GENERAL HOSPITAL OF GUANGZHOU MILITARY COMMAND   (China)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

^c GUANGDONG PROVINCIAL PEOPLE'S HOSPITAL   (China)

Author keywords

Apoptosis; Colorectal carcinoma; Sophora alopecuroides L.; Sophoridine; Traditional Chinese medicine

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 7; CASPASE 9; FLUOROURACIL; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PLANT EXTRACT; SOPHORIDINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BLOODY DIARRHEA; CANCER INHIBITION; CELL PROLIFERATION; CELL VIABILITY; CHINESE MEDICINE; COLORECTAL CARCINOMA; CONTROLLED STUDY; GROWTH RATE; HEALTH STATUS; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LD 50; LETHAL DOSE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SOPHORA; SOPHORA ALOPECUROIDES; TUMOR VOLUME; TUMOR XENOGRAFT; WEIGHT GAIN; WESTERN BLOTTING;

ALKALOIDS; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BLOTTING, WESTERN; CASPASES; CELL LINE, TUMOR; CELL PROLIFERATION; COLORECTAL NEOPLASMS; HUMANS; MALE; MEDICINE, CHINESE TRADITIONAL; MICE; MICE, NUDE; POLY(ADP-RIBOSE) POLYMERASES; QUINOLIZINES; SOPHORA; XENOGRAFT MODEL ANTITUMOR ASSAYS;

ANIMALIA; MUS; MUS MUSCULUS; SOPHORA ALOPECUROIDES;

EID: 84870290349     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2012.09.021     Document Type: Article

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