Fission Yeast 26S Proteasome Mutants Are Multi-Drug Resistant Due to Stabilization of the Pap1 Transcription Factor

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Penney, Mary ^a   Samejima, Itaru ^a   Wilkinson, Caroline R ^b   McInerny, Christopher J ^c   Mathiassen, Søs G ^e   Wallace, Mairi ^a   Toda, Takashi ^d   Hartmann Petersen, Rasmus ^e   Gordon, Colin ^a  

^a WESTERN GENERAL HOSPITAL   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

^d THE FRANCIS CRICK INSTITUTE   (United Kingdom)

^e UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

26S PROTEASOME; CARBAMIC ACID DERIVATIVE; METHYLBENZIMIDAZOL 2 YL CARBAMATE; PROTEASOME; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR PAP1; UBIQUITIN CONJUGATING ENZYME E2; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ARTICLE; CLONING; CONTROLLED STUDY; ESSENTIAL GENE; MULTIDRUG RESISTANCE; MUTANT; NONHUMAN; PROTEIN DEGRADATION; PROTEIN STABILITY; SCHIZOSACCHAROMYCES POMBE; TEMPERATURE SENSITIVITY; UBIQUITINATION;

BREFELDIN A; CAFFEINE; DRUG RESISTANCE, MULTIPLE; PROTEASOME ENDOPEPTIDASE COMPLEX; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE PROTEINS; STAUROSPORINE; UBIQUITINATION;

SCHIZOSACCHAROMYCETACEAE;

EID: 84870283783     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0050796     Document Type: Article

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