-
1
-
-
0024654957
-
+ which encodes a 115-kD protein preferentially localized in the nucleus and its periphery
-
+ which encodes a 115-kD protein preferentially localized in the nucleus and its periphery. J Cell Biol 108: 1195-1207.
-
(1989)
J Cell Biol
, vol.108
, pp. 1195-1207
-
-
Adachi, Y.1
Yanagida, M.2
-
2
-
-
33646573377
-
Impaired neurogenesis and cardiovascular development in mice lacking the E3 ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway
-
An, J.Y., Seo, J.W., Tasaki, T., Lee, M.J., Varshavsky, A., and Kwon, Y.T. (2006) Impaired neurogenesis and cardiovascular development in mice lacking the E3 ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway. Proc Natl Acad Sci USA 103: 6212-6217.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 6212-6217
-
-
An, J.Y.1
Seo, J.W.2
Tasaki, T.3
Lee, M.J.4
Varshavsky, A.5
Kwon, Y.T.6
-
3
-
-
76649112438
-
UBR2 mediates transcriptional silencing during spermatogenesis via histone ubiquitination
-
An, J.Y., Kim, E.A., Jiang, Y., Zakrzewska, A., Kim, D.E., Lee, M.J., etal. (2010) UBR2 mediates transcriptional silencing during spermatogenesis via histone ubiquitination. Proc Natl Acad Sci USA 107: 1912-1917.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 1912-1917
-
-
An, J.Y.1
Kim, E.A.2
Jiang, Y.3
Zakrzewska, A.4
Kim, D.E.5
Lee, M.J.6
-
4
-
-
78049369559
-
The ribonucleotide reductase inhibitor, Sml1, is sequentially phosphorylated, ubiquitylated and degraded in response to DNA damage
-
Andreson, B.L., Gupta, A., Georgieva, B.P., and Rothstein, R. (2010) The ribonucleotide reductase inhibitor, Sml1, is sequentially phosphorylated, ubiquitylated and degraded in response to DNA damage. Nucleic Acids Res 38: 6490-6501.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 6490-6501
-
-
Andreson, B.L.1
Gupta, A.2
Georgieva, B.P.3
Rothstein, R.4
-
5
-
-
0023003380
-
In vivo half-life of a protein is a function of its amino-terminal residue
-
Bachmair, A., Finley, D., and Varshavsky, A. (1986) In vivo half-life of a protein is a function of its amino-terminal residue. Science 234: 179-186.
-
(1986)
Science
, vol.234
, pp. 179-186
-
-
Bachmair, A.1
Finley, D.2
Varshavsky, A.3
-
6
-
-
0031818471
-
Heterologous modules for efficient and versatile PCR-based gene targeting in Schizosaccharomyces pombe
-
Bähler, J., Wu, J.Q., Longtine, M.S., Shah, N.G., McKenzie, A., 3rd, Steever, A.B., etal. (1998) Heterologous modules for efficient and versatile PCR-based gene targeting in Schizosaccharomyces pombe. Yeast 14: 943-951.
-
(1998)
Yeast
, vol.14
, pp. 943-951
-
-
Bähler, J.1
Wu, J.Q.2
Longtine, M.S.3
Shah, N.G.4
McKenzie 3rd, A.5
Steever, A.B.6
-
7
-
-
0025050840
-
The recognition component of the N-end rule pathway
-
Bartel, B., Wünning, I., and Varshavsky, A. (1990) The recognition component of the N-end rule pathway. EMBO J 9 3179-3189.
-
(1990)
EMBO J
, vol.9
, pp. 3179-3189
-
-
Bartel, B.1
Wünning, I.2
Varshavsky, A.3
-
8
-
-
0030746077
-
Caffeine-resistance in S. pombe: mutations in three novel caf genes increase caffeine tolerance and affect radiation sensitivity, fertility, and cell cycle
-
Benko, Z., Miklos, I., Carr, A.M., and Sipiczki, M. (1997) Caffeine-resistance in S. pombe: mutations in three novel caf genes increase caffeine tolerance and affect radiation sensitivity, fertility, and cell cycle. Curr Genet 31: 481-487.
-
(1997)
Curr Genet
, vol.31
, pp. 481-487
-
-
Benko, Z.1
Miklos, I.2
Carr, A.M.3
Sipiczki, M.4
-
9
-
-
68949161959
-
Genome-wide screen of genes required for caffeine tolerance in fission yeast
-
Calvo, I.A., Gabrielli, N., Iglesias-Baena, I., García-Santamarina, S., Hoe, K.L., Kim, D.U., etal. (2009) Genome-wide screen of genes required for caffeine tolerance in fission yeast. PLoS ONE 4: e6619.
-
(2009)
PLoS ONE
, vol.4
-
-
Calvo, I.A.1
Gabrielli, N.2
Iglesias-Baena, I.3
García-Santamarina, S.4
Hoe, K.L.5
Kim, D.U.6
-
10
-
-
0036047672
-
Diethylmaleate activates the transcription factor Pap1 by covalent modification of critical cysteine residues
-
Castillo, E.A., Ayté, J., Chiva, C., Moldón, A., Carrascal, M., Abián, J., etal. (2002) Diethylmaleate activates the transcription factor Pap1 by covalent modification of critical cysteine residues. Mol Microbiol 45: 245-254.
-
(2002)
Mol Microbiol
, vol.45
, pp. 245-254
-
-
Castillo, E.A.1
Ayté, J.2
Chiva, C.3
Moldón, A.4
Carrascal, M.5
Abián, J.6
-
11
-
-
0142135189
-
Schizosaccharomyces pombe cells lacking the Ran-binding protein Hba1 show a multidrug resistance phenotype due to constitutive nuclear accumulation of Pap1
-
Castillo, E.A., Vivancos, A.P., Jones, N., Ayte, J., and Hidalgo, E. (2003) Schizosaccharomyces pombe cells lacking the Ran-binding protein Hba1 show a multidrug resistance phenotype due to constitutive nuclear accumulation of Pap1. J Biol Chem 278: 40565-40572.
-
(2003)
J Biol Chem
, vol.278
, pp. 40565-40572
-
-
Castillo, E.A.1
Vivancos, A.P.2
Jones, N.3
Ayte, J.4
Hidalgo, E.5
-
12
-
-
12244267727
-
Global transcriptional responses of fission yeast to environmental stress
-
Chen, D., Toone, W.M., Mata, J., Lyne, R., Burns, G., Kivinen, K., etal. (2003) Global transcriptional responses of fission yeast to environmental stress. Mol Biol Cell 14: 214-229.
-
(2003)
Mol Biol Cell
, vol.14
, pp. 214-229
-
-
Chen, D.1
Toone, W.M.2
Mata, J.3
Lyne, R.4
Burns, G.5
Kivinen, K.6
-
13
-
-
38749120261
-
Multiple pathways differentially regulate global oxidative stress responses in fission yeast
-
Chen, D., Wilkinson, C.R., Watt, S., Penkett, C.J., Toone, W.M., Jones, N., and Bähler, J. (2008) Multiple pathways differentially regulate global oxidative stress responses in fission yeast. Mol Biol Cell 19: 308-317.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 308-317
-
-
Chen, D.1
Wilkinson, C.R.2
Watt, S.3
Penkett, C.J.4
Toone, W.M.5
Jones, N.6
Bähler, J.7
-
14
-
-
0033749641
-
A fission yeast homolog of Int-6, the mammalian oncoprotein and eIF3 subunit, induces drug resistance when overexpressed
-
Crane, R., Craig, R., Murray, R., Dunand-Sauthier, I., Humphrey, T., and Norbury, C. (2000) A fission yeast homolog of Int-6, the mammalian oncoprotein and eIF3 subunit, induces drug resistance when overexpressed. Mol Biol Cell 11: 3993-4003.
-
(2000)
Mol Biol Cell
, vol.11
, pp. 3993-4003
-
-
Crane, R.1
Craig, R.2
Murray, R.3
Dunand-Sauthier, I.4
Humphrey, T.5
Norbury, C.6
-
15
-
-
0034597012
-
2 sensing through oxidation of the Yap1 transcription factor
-
2 sensing through oxidation of the Yap1 transcription factor. EMBO J 19: 5157-5166.
-
(2000)
EMBO J
, vol.19
, pp. 5157-5166
-
-
Delaunay, A.1
Isnard, A.D.2
Toledano, M.B.3
-
16
-
-
0037195103
-
Pairs of dipeptides synergistically activate the binding of substrate by ubiquitin ligase through dissociation of its autoinhibitory domain
-
Du, F., Navarro-Garcia, F., Xia, Z., Tasaki, T., and Varshavsky, A. (2002) Pairs of dipeptides synergistically activate the binding of substrate by ubiquitin ligase through dissociation of its autoinhibitory domain. Proc Natl Acad Sci USA 99 14110-14115.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 14110-14115
-
-
Du, F.1
Navarro-Garcia, F.2
Xia, Z.3
Tasaki, T.4
Varshavsky, A.5
-
17
-
-
57049182407
-
Degradation of misfolded protein in the cytoplasm is mediated by the ubiquitin ligase Ubr1
-
Eisele, F., and Wolf, D.H. (2008) Degradation of misfolded protein in the cytoplasm is mediated by the ubiquitin ligase Ubr1. FEBS Lett 582: 4143-4146.
-
(2008)
FEBS Lett
, vol.582
, pp. 4143-4146
-
-
Eisele, F.1
Wolf, D.H.2
-
18
-
-
0033785699
-
Structural basis for the diversity of DNA recognition by bZIP transcription factors
-
Fujii, Y., Shimizu, T., Toda, T., Yanagida, M., and Hakoshima, T. (2000) Structural basis for the diversity of DNA recognition by bZIP transcription factors. Nat Struct Biol 7: 889-893.
-
(2000)
Nat Struct Biol
, vol.7
, pp. 889-893
-
-
Fujii, Y.1
Shimizu, T.2
Toda, T.3
Yanagida, M.4
Hakoshima, T.5
-
19
-
-
78651491709
-
Ubiquitin-proteasome genes as targets for modulation of cisplatin sensitivity in fission yeast
-
Gatti, L., Hoe, K.L., Hayles, J., Righetti, S.C., Carenini1, N., Laura Dal Bo, L.D., etal. (2011) Ubiquitin-proteasome genes as targets for modulation of cisplatin sensitivity in fission yeast. BMC Genomics 12: 44.
-
(2011)
BMC Genomics
, vol.12
, pp. 44
-
-
Gatti, L.1
Hoe, K.L.2
Hayles, J.3
Righetti, S.C.4
Carenini1, N.5
Laura Dal Bo, L.D.6
-
20
-
-
0027379925
-
Defective mitosis due to a mutation in the gene for a fission yeast 26S protease subunit
-
Gordon, C., McGurk, G., Dillon, P., Rosen, C., and Hastie, N.D. (1993) Defective mitosis due to a mutation in the gene for a fission yeast 26S protease subunit. Nature 366: 355-357.
-
(1993)
Nature
, vol.366
, pp. 355-357
-
-
Gordon, C.1
McGurk, G.2
Dillon, P.3
Rosen, C.4
Hastie, N.D.5
-
22
-
-
33745043951
-
Regulation of late G1/S phase transition and APC Cdh1 by reactive oxygen species
-
Havens, C.G., Ho, A., Yoshioka, N., and Dowdy, S.F. (2006) Regulation of late G1/S phase transition and APC Cdh1 by reactive oxygen species. Mol Cell Biol 26: 4701-4711.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 4701-4711
-
-
Havens, C.G.1
Ho, A.2
Yoshioka, N.3
Dowdy, S.F.4
-
23
-
-
75749101057
-
Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1
-
Heck, J.W., Cheung, S.K., and Hampton, R.Y. (2010) Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1. Proc Natl Acad Sci USA 107: 1106-1111.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 1106-1111
-
-
Heck, J.W.1
Cheung, S.K.2
Hampton, R.Y.3
-
25
-
-
27144557281
-
The N-end rule pathway as a nitric oxide sensor controlling the levels of multiple regulators
-
Hu, R.-G., Sheng, J., Qi, X., Xu, Z., Takahashi, T.T., and Varshavsky, A. (2005) The N-end rule pathway as a nitric oxide sensor controlling the levels of multiple regulators. Nature 437: 981-986.
-
(2005)
Nature
, vol.437
, pp. 981-986
-
-
Hu, R.-G.1
Sheng, J.2
Qi, X.3
Xu, Z.4
Takahashi, T.T.5
Varshavsky, A.6
-
26
-
-
0025827822
-
Characterization of PDR4, a Saccharomyces cerevisiae gene that confers pleiotropic drug resistance in high-copy number: identity with YAP1, encoding a transcriptional activator
-
Hussain, M., and Lenard, J. (1991) Characterization of PDR4, a Saccharomyces cerevisiae gene that confers pleiotropic drug resistance in high-copy number: identity with YAP1, encoding a transcriptional activator. Gene 101: 149-152.
-
(1991)
Gene
, vol.101
, pp. 149-152
-
-
Hussain, M.1
Lenard, J.2
-
27
-
-
60549096291
-
Two proteolytic pathways regulate DNA repair by cotargeting the Mgt1 alkylguanine transferase
-
Hwang, C.S., Shemorry, A., and Varshavsky, A. (2009) Two proteolytic pathways regulate DNA repair by cotargeting the Mgt1 alkylguanine transferase. Proc Natl Acad Sci USA 106: 2142-2147.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 2142-2147
-
-
Hwang, C.S.1
Shemorry, A.2
Varshavsky, A.3
-
28
-
-
12444257799
-
Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles
-
Itoh, K., Wakabayashi, N., Katoh, Y., Ishii, T., O'Connor, T., and Yamamoto, M. (2003) Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles. Genes Cells 8: 379-391.
-
(2003)
Genes Cells
, vol.8
, pp. 379-391
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
Ishii, T.4
O'Connor, T.5
Yamamoto, M.6
-
29
-
-
1942455887
-
Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles
-
Itoh, K., Tong, K.I., and Yamamoto, M. (2004) Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles. Free Radic Biol Med 36: 1208-1213.
-
(2004)
Free Radic Biol Med
, vol.36
, pp. 1208-1213
-
-
Itoh, K.1
Tong, K.I.2
Yamamoto, M.3
-
30
-
-
27744488466
-
Activation of AP-1-dependent transcription by a truncated translation initiation factor
-
Jenkins, C.C.L., Mata, J., Crane, R.F., Thomas, B., Akoulitchev, A., Bähler, J., and Norbury, C.J. (2005) Activation of AP-1-dependent transcription by a truncated translation initiation factor. Eukaryot Cell 4: 1840-1850.
-
(2005)
Eukaryot Cell
, vol.4
, pp. 1840-1850
-
-
Jenkins, C.C.L.1
Mata, J.2
Crane, R.F.3
Thomas, B.4
Akoulitchev, A.5
Bähler, J.6
Norbury, C.J.7
-
31
-
-
0035462049
-
Phosphorylation of Mei2 and Ste11 by Pat1 kinase inhibits sexual differentiation via ubiquitin proteolysis and 14-3-3 protein in fission yeast
-
Kitamura, K., Katayama, S., Shut, S., Sato, M., Watanabe, Y., Yamamoto, M., and Toda, T. (2001) Phosphorylation of Mei2 and Ste11 by Pat1 kinase inhibits sexual differentiation via ubiquitin proteolysis and 14-3-3 protein in fission yeast. Dev Cell 1: 389-399.
-
(2001)
Dev Cell
, vol.1
, pp. 389-399
-
-
Kitamura, K.1
Katayama, S.2
Shut, S.3
Sato, M.4
Watanabe, Y.5
Yamamoto, M.6
Toda, T.7
-
32
-
-
33344469643
-
Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Kaep1
-
Kobayashi, A., Kang, M.-I., Watai, Y., Tong, K.I., Shibata, T., Uchida, K., and Yamamoto, M. (2006) Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Kaep1. Mol Cell Biol 26: 221-229.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 221-229
-
-
Kobayashi, A.1
Kang, M.-I.2
Watai, Y.3
Tong, K.I.4
Shibata, T.5
Uchida, K.6
Yamamoto, M.7
-
33
-
-
0033591412
-
A novel nuclear export signal sensitive to oxidative stress in the fission yeast transcription factor Pap1
-
Kudo, N., Taoka, H., Toda, T., Yoshida, M., and Horinouchi, S. (1999) A novel nuclear export signal sensitive to oxidative stress in the fission yeast transcription factor Pap1. J Biol Chem 274: 15151-15158.
-
(1999)
J Biol Chem
, vol.274
, pp. 15151-15158
-
-
Kudo, N.1
Taoka, H.2
Toda, T.3
Yoshida, M.4
Horinouchi, S.5
-
34
-
-
0030942294
-
Regulation of yAP-1 nuclear localization in response to oxidative stress
-
Kuge, S., Jones, N., and Nomoto, A. (1997) Regulation of yAP-1 nuclear localization in response to oxidative stress. EMBO J 16: 1710-1720.
-
(1997)
EMBO J
, vol.16
, pp. 1710-1720
-
-
Kuge, S.1
Jones, N.2
Nomoto, A.3
-
35
-
-
0031595764
-
Crm1 (Xpo1) dependent nuclear export of the budding yeast transcription factor yAP-1 is sensitive to oxidative stress
-
Kuge, S., Toda, T., Iizuka, N., and Nomoto, A. (1998) Crm1 (Xpo1) dependent nuclear export of the budding yeast transcription factor yAP-1 is sensitive to oxidative stress. Genes Cells 3: 521-532.
-
(1998)
Genes Cells
, vol.3
, pp. 521-532
-
-
Kuge, S.1
Toda, T.2
Iizuka, N.3
Nomoto, A.4
-
36
-
-
0035726624
-
Regulation of the yeast Yap1p nuclear export signal is mediated by redox signal-induced reversible disulfide bond formation
-
Kuge, S., Arita, M., Murayama, A., Maeta, K., Izawa, S., Inoue, Y., and Nomoto, A. (2001) Regulation of the yeast Yap1p nuclear export signal is mediated by redox signal-induced reversible disulfide bond formation. Mol Cell Biol 21: 6139-6150.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 6139-6150
-
-
Kuge, S.1
Arita, M.2
Murayama, A.3
Maeta, K.4
Izawa, S.5
Inoue, Y.6
Nomoto, A.7
-
38
-
-
0032493449
-
The mouse and human genes encoding the recognition component of the N-end rule pathway
-
Kwon, Y.T., Reiss, Y., Fried, V.A., Hershko, A., Yoon, J.K., Gonda, D.K., etal. (1998) The mouse and human genes encoding the recognition component of the N-end rule pathway. Proc Natl Acad Sci USA 95: 7898-7903.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 7898-7903
-
-
Kwon, Y.T.1
Reiss, Y.2
Fried, V.A.3
Hershko, A.4
Yoon, J.K.5
Gonda, D.K.6
-
39
-
-
0242664014
-
Female lethality and apoptosis of spermatocytes in mice lacking the UBR ubiquitin ligase of the N-end rule pathway
-
Kwon, Y.T., Xia, Z., An, J.Y., Tasaki, T., Davydov, I.V., Seo, J.W., etal. (2003) Female lethality and apoptosis of spermatocytes in mice lacking the UBR ubiquitin ligase of the N-end rule pathway. Mol Cell Biol 23: 8255-8271.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 8255-8271
-
-
Kwon, Y.T.1
Xia, Z.2
An, J.Y.3
Tasaki, T.4
Davydov, I.V.5
Seo, J.W.6
-
40
-
-
10244240475
-
pDUAL, a multipurpose, multicopy vector capable of chromosomal integration in fission yeast
-
Matsuyama, A., Shirai, A., Yashiroda, Y., Kamata, A., Horinouchi, S., and Yoshida, M. (2004) pDUAL, a multipurpose, multicopy vector capable of chromosomal integration in fission yeast. Yeast 21: 1289-1305.
-
(2004)
Yeast
, vol.21
, pp. 1289-1305
-
-
Matsuyama, A.1
Shirai, A.2
Yashiroda, Y.3
Kamata, A.4
Horinouchi, S.5
Yoshida, M.6
-
41
-
-
44449176696
-
A series of promoters for constitutive expression of heterologous genes in fission yeast
-
Matsuyama, A., Shirai, A., and Yoshida, M. (2008) A series of promoters for constitutive expression of heterologous genes in fission yeast. Yeast 25: 371-376.
-
(2008)
Yeast
, vol.25
, pp. 371-376
-
-
Matsuyama, A.1
Shirai, A.2
Yoshida, M.3
-
42
-
-
0027390036
-
Thiamine-repressible expression vectors pREP and pRIP for fission yeast
-
Maundrell, K. (1993a) Thiamine-repressible expression vectors pREP and pRIP for fission yeast. Gene 123: 127-130.
-
(1993)
Gene
, vol.123
, pp. 127-130
-
-
Maundrell, K.1
-
43
-
-
0027441494
-
TATA box mutations in Schizosaccharomyces pombe nmt1 promoter affect transcription efficiency but not the transcription start point or thiamine repressibility
-
Maundrell, K. (1993b) TATA box mutations in Schizosaccharomyces pombe nmt1 promoter affect transcription efficiency but not the transcription start point or thiamine repressibility. Gene 123: 131-136.
-
(1993)
Gene
, vol.123
, pp. 131-136
-
-
Maundrell, K.1
-
44
-
-
0026025891
-
Molecular genetic analysis of fission yeast Schizosaccharomyces pombe
-
Moreno, S., Klar, A., and Nurse, P. (1991) Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. Methods Enzymol 194: 795-823.
-
(1991)
Methods Enzymol
, vol.194
, pp. 795-823
-
-
Moreno, S.1
Klar, A.2
Nurse, P.3
-
45
-
-
0038660703
-
Identification of Uhp1, a ubiquitinated histone-like protein, as a target/mediator of Rhp6 in mating-type silencing in fission yeast
-
Naresh, A., Saini, S., and Singh, J. (2003) Identification of Uhp1, a ubiquitinated histone-like protein, as a target/mediator of Rhp6 in mating-type silencing in fission yeast. J Biol Chem 278: 9185-9194.
-
(2003)
J Biol Chem
, vol.278
, pp. 9185-9194
-
-
Naresh, A.1
Saini, S.2
Singh, J.3
-
46
-
-
77954196466
-
Ubr1 and ubr2 function in a quality control pathway for degradation of unfolded cytosolic proteins
-
Nillegoda, N.B., Theodoraki, M.A., Mandal, A.K., Mayo, K.J., Ren, H.Y., Sultana, R., etal. (2010) Ubr1 and ubr2 function in a quality control pathway for degradation of unfolded cytosolic proteins. Mol Biol Cell 21: 2102-2116.
-
(2010)
Mol Biol Cell
, vol.21
, pp. 2102-2116
-
-
Nillegoda, N.B.1
Theodoraki, M.A.2
Mandal, A.K.3
Mayo, K.J.4
Ren, H.Y.5
Sultana, R.6
-
47
-
-
33646007680
-
Loss of Ubr2, an E3 ubiquitin ligase, leads to chromosome fragility and impaired homologous recombinational repair
-
Ouyang, Y., Kwon, Y.T., An, J.Y., Eller, D., Tsai, S.-C., Diaz-Perez, S., etal. (2006) Loss of Ubr2, an E3 ubiquitin ligase, leads to chromosome fragility and impaired homologous recombinational repair. Mutat Res 596: 64-75.
-
(2006)
Mutat Res
, vol.596
, pp. 64-75
-
-
Ouyang, Y.1
Kwon, Y.T.2
An, J.Y.3
Eller, D.4
Tsai, S.-C.5
Diaz-Perez, S.6
-
48
-
-
77954178073
-
A nucleus-based quality control mechanism for cytosolic proteins
-
Prasad, R., Kawaguchi, S., and Ng, D.T. (2010) A nucleus-based quality control mechanism for cytosolic proteins. Mol Biol Cell 21: 2117-2127.
-
(2010)
Mol Biol Cell
, vol.21
, pp. 2117-2127
-
-
Prasad, R.1
Kawaguchi, S.2
Ng, D.T.3
-
50
-
-
0035912183
-
Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability
-
Rao, H., Uhlmann, F., Nasmyth, K., and Varshavsky, A. (2001) Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability. Nature 410: 955-959.
-
(2001)
Nature
, vol.410
, pp. 955-959
-
-
Rao, H.1
Uhlmann, F.2
Nasmyth, K.3
Varshavsky, A.4
-
51
-
-
33749057086
-
Spatiotemporal regulation of c-Fos by ERK5 and the E3 ubiquitin ligase UBR1, and its biological role
-
Sasaki, T., Kojima, H., Kishimoto, R., Ikeda, A., Kunimoto, H., and Nakajima, K. (2006) Spatiotemporal regulation of c-Fos by ERK5 and the E3 ubiquitin ligase UBR1, and its biological role. Mol Cell 24: 63-75.
-
(2006)
Mol Cell
, vol.24
, pp. 63-75
-
-
Sasaki, T.1
Kojima, H.2
Kishimoto, R.3
Ikeda, A.4
Kunimoto, H.5
Nakajima, K.6
-
52
-
-
0028898060
-
+-dependent transcription and is implicated in the maintenance of chromosome structure
-
+-dependent transcription and is implicated in the maintenance of chromosome structure. J Cell Sci 108: 569-579.
-
(1995)
J Cell Sci
, vol.108
, pp. 569-579
-
-
Shimanuki, M.1
Saka, Y.2
Yanagida, M.3
Toda, T.4
-
53
-
-
0030728770
-
Resistance to diverse drugs and ultraviolet light conferred by overexpression of a novel human 26 S proteasome subunit
-
Spataro, V., Toda, T., Craig, R., Seeger, M., Dubiel, W., Harris, A.L., and Norbury, C. (1997) Resistance to diverse drugs and ultraviolet light conferred by overexpression of a novel human 26 S proteasome subunit. J Biol Chem 272: 30470-30475.
-
(1997)
J Biol Chem
, vol.272
, pp. 30470-30475
-
-
Spataro, V.1
Toda, T.2
Craig, R.3
Seeger, M.4
Dubiel, W.5
Harris, A.L.6
Norbury, C.7
-
54
-
-
0034739543
-
Application of the chromatin immunoprecipitation method to identify in vivo protein-DNA associations in fission yeast
-
Takahashi, K., Saitoh, S., and Yanagida, M. (2000) Application of the chromatin immunoprecipitation method to identify in vivo protein-DNA associations in fission yeast. Sci STKE 56: pl1.
-
(2000)
Sci STKE
, vol.56
-
-
Takahashi, K.1
Saitoh, S.2
Yanagida, M.3
-
55
-
-
35548974677
-
The mammalian N-end rule pathway: new insights into its components and physiological roles
-
Tasaki, T., and Kwon, Y.T. (2007) The mammalian N-end rule pathway: new insights into its components and physiological roles. Trends Biochem Sci 32: 520-528.
-
(2007)
Trends Biochem Sci
, vol.32
, pp. 520-528
-
-
Tasaki, T.1
Kwon, Y.T.2
-
56
-
-
34547117631
-
Biochemical and genetic studies of UBR3, a ubiquitin ligase with a function in olfactory and other sensory systems
-
Tasaki, T., Sohr, R., Xia, Z., Hwllweg, R., Hörtnag, I., Varshavsky, A., and Kwon, Y.T. (2007) Biochemical and genetic studies of UBR3, a ubiquitin ligase with a function in olfactory and other sensory systems. J Biol Chem 282: 18510-18520.
-
(2007)
J Biol Chem
, vol.282
, pp. 18510-18520
-
-
Tasaki, T.1
Sohr, R.2
Xia, Z.3
Hwllweg, R.4
Hörtnag, I.5
Varshavsky, A.6
Kwon, Y.T.7
-
57
-
-
0025977196
-
Fission yeast genes that confer resistance to staurosporine encode an AP-1 like transcription factor and a protein kinase related to the mammalian ERK1/MAP2 and budding yeast FUS3 and KSS1 kinases
-
Toda, T., Shimanuki, M., and Yanagida, M. (1991) Fission yeast genes that confer resistance to staurosporine encode an AP-1 like transcription factor and a protein kinase related to the mammalian ERK1/MAP2 and budding yeast FUS3 and KSS1 kinases. Genes Dev 5: 60-73.
-
(1991)
Genes Dev
, vol.5
, pp. 60-73
-
-
Toda, T.1
Shimanuki, M.2
Yanagida, M.3
-
58
-
-
0026466825
-
Fission yeast pap1-dependent transcription is negatively regulated by an essential nuclear protein, crm1
-
Toda, T., Shimanuki, M., Saka, Y., Yamano, H., Adachi, Y., Shirakawa, M., etal. (1992) Fission yeast pap1-dependent transcription is negatively regulated by an essential nuclear protein, crm1. Mol Cell Biol 12: 5474-5484.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 5474-5484
-
-
Toda, T.1
Shimanuki, M.2
Saka, Y.3
Yamano, H.4
Adachi, Y.5
Shirakawa, M.6
-
59
-
-
0032523783
-
Regulation of the fission yeast transcription factor Pap1 by oxidative stress: requirement for the nuclear export factor Crm1 (exportin) and the stress-activated MAP kinase Sty1/Spc1
-
Toone, W.M., Kuge, S., Samuels, M., Morgan, B.A., Toda, T., and Jones, N. (1998) Regulation of the fission yeast transcription factor Pap1 by oxidative stress: requirement for the nuclear export factor Crm1 (exportin) and the stress-activated MAP kinase Sty1/Spc1. Genes Dev 12: 1453-1463.
-
(1998)
Genes Dev
, vol.12
, pp. 1453-1463
-
-
Toone, W.M.1
Kuge, S.2
Samuels, M.3
Morgan, B.A.4
Toda, T.5
Jones, N.6
-
60
-
-
0035971410
-
Redox control of AP-1-like factors in yeast and beyond
-
Toone, W.M., Morgan, B.A., and Jones, N. (2001) Redox control of AP-1-like factors in yeast and beyond. Oncogene 20: 2336-2346.
-
(2001)
Oncogene
, vol.20
, pp. 2336-2346
-
-
Toone, W.M.1
Morgan, B.A.2
Jones, N.3
-
61
-
-
0027992519
-
Brefeldin A sensitivity and resistance in Schizosaccharomyces pombe
-
Turi, T.G., Webster, P., and Rose, J.K. (1994) Brefeldin A sensitivity and resistance in Schizosaccharomyces pombe. J Biol Chem 269: 24229-24236.
-
(1994)
J Biol Chem
, vol.269
, pp. 24229-24236
-
-
Turi, T.G.1
Webster, P.2
Rose, J.K.3
-
62
-
-
0029882795
-
Characterization of a nuclear protein conferring brefeldin A resistance in Schizosaccharomyces pombe
-
Turi, T.G., Mueller, U.W., Sazer, S., and Rose, J.K. (1996) Characterization of a nuclear protein conferring brefeldin A resistance in Schizosaccharomyces pombe. J Biol Chem 271 9166-9171.
-
(1996)
J Biol Chem
, vol.271
, pp. 9166-9171
-
-
Turi, T.G.1
Mueller, U.W.2
Sazer, S.3
Rose, J.K.4
-
63
-
-
0034213352
-
Peptides accelerate their uptake by activating a ubiquitin-dependent proteolytic pathway
-
Turner, G.C., Du, F., and Varshavsky, A. (2000) Peptides accelerate their uptake by activating a ubiquitin-dependent proteolytic pathway. Nature 405: 579-583.
-
(2000)
Nature
, vol.405
, pp. 579-583
-
-
Turner, G.C.1
Du, F.2
Varshavsky, A.3
-
64
-
-
0029861143
-
The N-end rule: functions, mysteries, uses
-
Varshavsky, A. (1996) The N-end rule: functions, mysteries, uses. Proc Natl Acad Sci USA 93: 12142-12149.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 12142-12149
-
-
Varshavsky, A.1
-
65
-
-
2942538583
-
Activation of the redox sensor Pap1 by hydrogen peroxide requires modulation of the intracellular oxidant concentration
-
Vivancos, A.P., Castillo, E.A., Jones, N., Ayté, J., and Hidalgo, E. (2004) Activation of the redox sensor Pap1 by hydrogen peroxide requires modulation of the intracellular oxidant concentration. Mol Microbiol 52: 1424-1435.
-
(2004)
Mol Microbiol
, vol.52
, pp. 1424-1435
-
-
Vivancos, A.P.1
Castillo, E.A.2
Jones, N.3
Ayté, J.4
Hidalgo, E.5
-
67
-
-
0242329881
-
Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation
-
Wakabayashi, N., Itoh, K., Wakabayashi, J., Motohashi, H., Noda, S., Takahashi, S., etal. (2003) Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation. Nat Genet 35: 238-245.
-
(2003)
Nat Genet
, vol.35
, pp. 238-245
-
-
Wakabayashi, N.1
Itoh, K.2
Wakabayashi, J.3
Motohashi, H.4
Noda, S.5
Takahashi, S.6
-
68
-
-
11244343965
-
Rpn4 is a physiological substrate of the Ubr2 ubiquitin ligase
-
Wang, L., Mao, X., Ju, D., and Xie, Y. (2004) Rpn4 is a physiological substrate of the Ubr2 ubiquitin ligase. J Biol Chem 279: 55218-55223.
-
(2004)
J Biol Chem
, vol.279
, pp. 55218-55223
-
-
Wang, L.1
Mao, X.2
Ju, D.3
Xie, Y.4
-
69
-
-
0029130168
-
Identification of a signal for rapid export of proteins from the nucleus
-
Wen, W., Meinkoth, J.L., Tsien, R.Y., and Taylor, S.S. (1995) Identification of a signal for rapid export of proteins from the nucleus. Cell 82: 463-473.
-
(1995)
Cell
, vol.82
, pp. 463-473
-
-
Wen, W.1
Meinkoth, J.L.2
Tsien, R.Y.3
Taylor, S.S.4
-
70
-
-
0037472980
-
A simple Cre-loxP method for chromosomal N-terminal tagging of essential and non-essential Schizosaccharomyces pombe genes
-
Werler, P.J.H., Hartsuiker, E., and Carr, A.M. (2003) A simple Cre-loxP method for chromosomal N-terminal tagging of essential and non-essential Schizosaccharomyces pombe genes. Gene 304: 133-141.
-
(2003)
Gene
, vol.304
, pp. 133-141
-
-
Werler, P.J.H.1
Hartsuiker, E.2
Carr, A.M.3
-
71
-
-
0030808452
-
Mts4, a non-ATPase subunit of the 26 S protease in fission yeast is essential for mitosis and interacts directly with the ATPase subunit Mts2
-
Wilkinson, C.R., Wallace, M., Seeger, M., Dubiel, W., and Gordon, C. (1997) Mts4, a non-ATPase subunit of the 26 S protease in fission yeast is essential for mitosis and interacts directly with the ATPase subunit Mts2. J Biol Chem 272: 25768-25777.
-
(1997)
J Biol Chem
, vol.272
, pp. 25768-25777
-
-
Wilkinson, C.R.1
Wallace, M.2
Seeger, M.3
Dubiel, W.4
Gordon, C.5
-
72
-
-
57649223684
-
Amino acids induce peptide uptake via accelerated degradation of Cup9, the transcriptional repressor of the PTR2 peptide transporter
-
Xia, Z., Turner, G.C., Hwang, C.-S., Byrd, C., and Varshavsky, A. (2008) Amino acids induce peptide uptake via accelerated degradation of Cup9, the transcriptional repressor of the PTR2 peptide transporter. J Biol Chem 283: 28958-28968.
-
(2008)
J Biol Chem
, vol.283
, pp. 28958-28968
-
-
Xia, Z.1
Turner, G.C.2
Hwang, C.-S.3
Byrd, C.4
Varshavsky, A.5
-
73
-
-
0032476011
-
RNA-assisted nuclear transport of the meiotic regulator Mei2p in fission yeast
-
Yamashita, A., Watanabe, Y., Nukina, N., and Yamamoto, M. (1998) RNA-assisted nuclear transport of the meiotic regulator Mei2p in fission yeast. Cell 95: 115-123.
-
(1998)
Cell
, vol.95
, pp. 115-123
-
-
Yamashita, A.1
Watanabe, Y.2
Nukina, N.3
Yamamoto, M.4
-
74
-
-
28444458475
-
Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome)
-
Zenker, M., Meyerle, J., Lerch, M.M., Tagariello, A., Zerres, K., Durie, P.R., etal. (2005) Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome). Nat Genet 37: 1345-1350.
-
(2005)
Nat Genet
, vol.37
, pp. 1345-1350
-
-
Zenker, M.1
Meyerle, J.2
Lerch, M.M.3
Tagariello, A.4
Zerres, K.5
Durie, P.R.6
-
75
-
-
10044228504
-
Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex
-
Zhang, D.D., Lo, S.-C., Cross, J.V., Templeton, D.J., and Mannik, M. (2004) Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex. Mol Cell Biol 24: 10941-10953.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 10941-10953
-
-
Zhang, D.D.1
Lo, S.-C.2
Cross, J.V.3
Templeton, D.J.4
Mannik, M.5
-
76
-
-
27744536479
-
The glycolytic metabolite methylglyoxal activates Pap1 and Sty1 stress responses in Schizosaccharomyces pombe
-
Zuin, A., Vivancos, A.P., Sansó, M., Takatsume, Y., Ayté, J., Inoue, Y., and Hidalgo, E. (2005) The glycolytic metabolite methylglyoxal activates Pap1 and Sty1 stress responses in Schizosaccharomyces pombe. J Biol Chem 280: 36708-36713.
-
(2005)
J Biol Chem
, vol.280
, pp. 36708-36713
-
-
Zuin, A.1
Vivancos, A.P.2
Sansó, M.3
Takatsume, Y.4
Ayté, J.5
Inoue, Y.6
Hidalgo, E.7
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