Zn2+ enhancement of the recombinant 5-HT3 receptor is modulated by divalent cations

European Journal of Pharmacology

Volumn 394, Issue 2-3, 2000, Pages 189-197

  Hubbard, Peter C ^a,b   Lummis, Sarah C R ^a,b  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

5 HT3 receptor; Cation; Divalent; Neuromodulation; Radioligand binding; Voltage clamp; Whole cell; Zn2+

Indexed keywords

1 (3 CHLOROPHENYL)BIGUANIDE; 1,2,3,9 TETRAHYDRO[(5 METHYL 1H IMIDAZOL 4 YL)METHYL] 9 METHYL 4H CARAZOL 4 ONE; CALCIUM ION; DIVALENT CATION; GR 67330; GRANISETRON; MAGNESIUM ION; RADIOLIGAND; RECEPTOR SUBUNIT; RECOMBINANT RECEPTOR; SEROTONIN; SEROTONIN 3 RECEPTOR; SEROTONIN AGONIST; SEROTONIN ANTAGONIST; TRITIUM; UNCLASSIFIED DRUG; ZINC ION;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DESENSITIZATION; ELECTROPHYSIOLOGY; EMBRYO CELL; GENETIC TRANSFECTION; HALF LIFE TIME; HUMAN; HUMAN CELL; KIDNEY CELL; MEMBRANE CURRENT; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; RADIOASSAY; VOLTAGE CLAMP;

CALCIUM; CATIONS; CELL LINE; ELECTROPHYSIOLOGY; HUMANS; INDICATORS AND REAGENTS; ION CHANNELS; KIDNEY; MAGNESIUM; RADIOLIGAND ASSAY; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT3; RECOMBINANT PROTEINS; SEROTONIN AGONISTS; ZINC;

EID: 0034647080     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00143-6     Document Type: Article

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