메뉴 건너뛰기




Volumn 16, Issue , 2008, Pages 129-142

Composition of neurofibromas, NF1 expression, and comparison of normal and NF1 haploinsufficient cells

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84870209838     PISSN: 00770876     EISSN: 16623835     Source Type: Book Series    
DOI: 10.1159/000126565     Document Type: Article
Times cited : (3)

References (61)
  • 3
    • 0037012848 scopus 로고    scopus 로고
    • Neurofibromas in NF1: Schwann cell origin and role of tumor environment
    • DOI 10.1126/science.1068452
    • Zhu Y, Ghosh P, Charnay P, Burns DK, Parada LF: Neurofibromas in NF1: Schwann cell origin and role of tumor environment. Science 2002;296:920-922. (Pubitemid 34464899)
    • (2002) Science , vol.296 , Issue.5569 , pp. 920-922
    • Zhu, Y.1    Ghosh, P.2    Charnay, P.3    Burns, D.K.4    Parada, L.F.5
  • 5
    • 0022642615 scopus 로고
    • Ultrastructural localization of S-100 protein in neurofibroma
    • Hirose T, Sano T, Hizawa K: Ultrastructural localization of S-100 protein in neurofibroma. Acta Neuropathol (Berl) 1986;69:103-110. (Pubitemid 16146257)
    • (1986) Acta Neuropathologica , vol.69 , Issue.1-2 , pp. 103-110
    • Hirose, T.1    Sano, T.2    Hizawa, K.3
  • 6
    • 0017240028 scopus 로고
    • Some electron microscopic and autoradiographic results concerning cutaneous neurofibromas in von Recklinghausen's disease
    • Lassmann H, Jurecka W, Gebhart W: Some electron microscopic and autoradiographic results concerning cutaneous neurofibromas in von Recklinghausen's disease. Arch Dermatol Res 1976;255:69-81.
    • (1976) Arch Dermatol Res , vol.255 , pp. 69-81
    • Lassmann, H.1    Jurecka, W.2    Gebhart, W.3
  • 7
    • 0022924114 scopus 로고
    • The nerve growth factor receptor in normal and transformed neural crest cells
    • Ross AH, Herlyn M, Maul GG, Koprowski H, Bothwell M, et al: The nerve growth factor receptor in normal and transformed neural crest cells. Ann N Y Acad Sci 1986;486:115-123. (Pubitemid 17027493)
    • (1986) Annals of the New York Academy of Sciences , vol.486 , pp. 115-123
    • Ross, A.H.1    Herlyn, M.2    Maul, G.G.3
  • 8
    • 13244291508 scopus 로고    scopus 로고
    • Tumor suppressor mutations and growth factor signaling in the pathogenesis of NF1-associated peripheral nerve sheath tumors: II. The role of dysregulated growth factor signaling
    • Carroll SL, Stonecypher MS: Tumor suppressor mutations and growth factor signaling in the pathogenesis of NF1-associated peripheral nerve sheath tumors: II. The role of dysregulated growth factor signaling. J Neuropathol Exp Neurol 2005;64:1-9. (Pubitemid 40189473)
    • (2005) Journal of Neuropathology and Experimental Neurology , vol.64 , Issue.1 , pp. 1-9
    • Carroll, S.L.1    Stonecypher, M.S.2
  • 9
    • 0020082369 scopus 로고
    • Peripheral nerve sheath tumors: An electron microscopic study of 43 cases
    • Erlandson RA, Woodruff JM: Peripheral nerve sheath tumors: an electron microscopic study of 43 cases. Cancer 1982;49:273-287. (Pubitemid 12211842)
    • (1982) Cancer , vol.49 , Issue.2 , pp. 273-287
    • Erlandson, R.A.1    Woodruff, J.M.2
  • 10
    • 0023520223 scopus 로고
    • Expression of epithelial membrane antigen in perineurial cells and their derivatives. An immunohistochemical study with multiple markers
    • DOI 10.1007/BF00687077
    • Perentes E, Nakagawa Y, Ross GW, Stanton C, Rubinstein LJ: Expression of epithelial membrane antigen in perineurial cells and their derivatives. An immunohistochemical study with multiple markers. Acta Neuropathol (Berl) 1987;75:160-165. (Pubitemid 18011899)
    • (1987) Acta Neuropathologica , vol.75 , Issue.2 , pp. 160-165
    • Perentes, E.1    Nakagawa, Y.2    Ross, G.W.3    Stanton, C.4    Rubinstein, L.J.5
  • 11
    • 0037395235 scopus 로고    scopus 로고
    • Immunohistochemical demonstration of EMA/Glut1-positive perineurial cells and CD34-positive fibroblastic cells in peripheral nerve sheath tumors
    • DOI 10.1097/01.MP.0000062654.83617.B7
    • Hirose T, Tani T, Shimada T, Ishizawa K, Shimada S, Sano T: Immunohistochemical demonstration of EMA/Glut1-positive perineurial cells and CD34-positive fibroblastic cells in peripheral nerve sheath tumors. Mod Pathol 2003;16:293-298. (Pubitemid 36443977)
    • (2003) Modern Pathology , vol.16 , Issue.4 , pp. 293-298
    • Hirose, T.1    Tani, T.2    Shimada, T.3    Ishizawa, K.4    Shimada, S.5    Sano, T.6
  • 12
    • 0033852186 scopus 로고    scopus 로고
    • Oscillation and rapid changes of NF1 mRNA steady-state levels in cultured human keratinocytes
    • Pummi K, Yla-Outinen H, Peltonen J: Oscillation and rapid changes of NF1 mRNA steady-state levels in cultured human keratinocytes. Arch Dermatol Res 2000;8:422-424. (Pubitemid 30618110)
    • (2000) Archives of Dermatological Research , vol.292 , Issue.8 , pp. 422-424
    • Pummi, K.1    Yla-Outinen, H.2    Peltonen, J.3
  • 13
    • 0022347002 scopus 로고
    • Peripheral nerve sheath tumors
    • Erlandson RA: Peripheral nerve sheath tumors. Ultrastruct Pathol 1985;9:113-122. (Pubitemid 16189770)
    • (1985) Ultrastructural Pathology , vol.9 , Issue.1-2 , pp. 113-122
    • Erlandson, R.A.1
  • 16
    • 0024324102 scopus 로고
    • Type 1 neurofibromatosis: Selective expression of extracellular matrix genes by Schwann cells, perineurial cells, and fibroblasts in mixed cultures
    • Jaakkola S, Peltonen J, Riccardi V, Chu ML, Uitto J: Type 1 neurofibromatosis: selective expression of extracellular matrix genes by Schwann cells, perineurial cells, and fibroblasts in mixed cultures. J Clin Invest 1989;84:253-261. (Pubitemid 19170117)
    • (1989) Journal of Clinical Investigation , vol.84 , Issue.1 , pp. 253-261
    • Jaakkola, S.1    Peltonen, J.2    Riccardi, V.3    Chu, M.-L.4    Uitto, J.5
  • 17
    • 24344496841 scopus 로고    scopus 로고
    • Analysis of NF1 transcriptional regulatory elements
    • DOI 10.1002/ajmg.a.30699
    • Lee TK, Friedman JM: Analysis of NF1 transcriptional regulatory elements. Am J Med Genet A 2005;137:130-135. (Pubitemid 41262678)
    • (2005) American Journal of Medical Genetics , vol.137 A , Issue.2 , pp. 130-135
    • Lee, T.K.1    Friedman, J.M.2
  • 18
    • 0029360604 scopus 로고
    • Regulation of neurofibromin expression in rat sciatic nerve and cultured Schwann cells
    • Wrabetz L, Feltri ML, Kim H, Daston M, Kamholz J, et al: Regulation of neurofibromin expression in rat sciatic nerve and cultured Schwann cells. Glia 1995;15:22-32.
    • (1995) Glia , vol.15 , pp. 22-32
    • Wrabetz, L.1    Feltri, M.L.2    Kim, H.3    Daston, M.4    Kamholz, J.5
  • 19
    • 0031919430 scopus 로고    scopus 로고
    • Upregulation of tumor suppressor protein neurofibromin in normal human wound healing and in vitro evidence for platelet derived growth factor (PDGF) and transforming growth factor-β1 (TGF-β1) elicited increase in neurofibromin mRNA steady-state levels in dermal fibroblasts
    • DOI 10.1046/j.1523-1747.1998.00108.x
    • Ylä-Outinen H, Aaltonen V, Björkstrand A-S, Hirvonen O, Lakkakorpi J, et al: Upregulation of tumor suppressor protein neurofibromin in normal wound healing and in vitro evidence for platelet derived growth factor (PDGF) and transforming growth factor-β1 (TGF-β1) elicited increase in neurofibromin mRNA steady-state levels in dermal fibroblasts. J Invest Dermatol 1998;110:232-237. (Pubitemid 28144597)
    • (1998) Journal of Investigative Dermatology , vol.110 , Issue.3 , pp. 232-237
    • Yla-Outinen, H.1    Aaltonen, V.2    Bjorkstrand, A.-S.3    Hirvonen, O.4    Lakkakorpi, J.5    Vaha-Kreula, M.6    Laato, M.7    Peltonen, J.8
  • 20
    • 0033001620 scopus 로고    scopus 로고
    • The Nf1 tumor suppressor regulates mouse skin wound healing, fibroblast proliferation, and collagen deposited by fibroblasts
    • DOI 10.1046/j.1523-1747.1999.00609.x
    • Atit RP, Crowe MJ, Greenhalgh DG, Wenstrup RJ, Ratner N: The Nf1 tumor suppressor regulates mouse skin wound healing, fibroblast proliferation, and collagen deposited by fibroblasts. J Invest Dermatol 1999;112:835-842. (Pubitemid 29277981)
    • (1999) Journal of Investigative Dermatology , vol.112 , Issue.6 , pp. 835-842
    • Atit, R.P.1    Crowe, M.J.2    Greenhalgh, D.G.3    Wenstrup, R.J.4    Ratner, N.5
  • 23
    • 16644392408 scopus 로고    scopus 로고
    • NF1 tumor suppressor protein and mRNA in skeletal tissues of developing and adult normal mouse and NF1-deficient embryos
    • DOI 10.1359/JBMR.040130
    • Kuorilehto T, Nissinen M, Koivunen J, Benson MD, Peltonen J: NF1 tumor suppressor protein and mRNA in skeletal tissues of developing and adult normal mouse and NF1-deficient embryos. J Bone Miner Res 2004;19:983-989. (Pubitemid 41103455)
    • (2004) Journal of Bone and Mineral Research , vol.19 , Issue.6 , pp. 983-989
    • Kuorilehto, T.1    Nissinen, M.2    Koivunen, J.3    Benson, M.D.4    Peltonen, J.5
  • 24
    • 0031059599 scopus 로고    scopus 로고
    • Post-transcriptional regulation of neurofibromin level in cultured human melanocytes in response to growth factors
    • Griesser J, Kaufmann D, Maier B, Mailhammer R, Kuehl P, Krone W: Post-transcriptional regulation of neurofibromin level in cultured human melanocytes in response to growth factors. J Invest Dermatol 1997;108:275-280. (Pubitemid 27116223)
    • (1997) Journal of Investigative Dermatology , vol.108 , Issue.3 , pp. 275-280
    • Griesser, J.1    Kaufmann, D.2    Maier, B.3    Mailhammer, R.4    Kuehl, P.5    Krone, W.6
  • 25
    • 0037443055 scopus 로고    scopus 로고
    • Dynamic regulation of the Ras pathway via proteolysis of the NF1 tumor suppressor
    • DOI 10.1101/gad.1054703
    • Cichowski K, Santiago S, Jardim M, Johnson BW, Jacks T: Dynamic regulation of the Ras pathway via proteolysis of the NF1 tumor suppressor. Genes Dev 2003;17:449-454. (Pubitemid 36258759)
    • (2003) Genes and Development , vol.17 , Issue.4 , pp. 449-454
    • Cichowski, K.1    Santiago, S.2    Jardim, M.3    Johnson, B.W.4    Jacks, T.5
  • 26
    • 0025909212 scopus 로고
    • Differential expression of two types of the neurofibromatosis type 1 (NF1) gene transcripts related to neuronal differentiation
    • Nishi T, Lee PS, Oka K, Levin VA, Tanase S, et al: Differential expression of two types of the neurofibromatosis type 1 (NF1) gene transcripts related to neuronal differentiation. Oncogene 1991;6:1555-1559. (Pubitemid 21924257)
    • (1991) Oncogene , vol.6 , Issue.9 , pp. 1555-1559
    • Nishi, T.1    Lee, P.S.Y.2    Oka, K.3    Levin, V.A.4    Tanase, S.5    Morino, Y.6    Saya, H.7
  • 27
    • 0028935019 scopus 로고
    • Expression of two new protein isoforms of the neurofibromatosis type 1 gene product, neurofibromin, in muscle tissues
    • Gutmann DH, Geist RT, Rose K, Wright DE: Expression of two new protein isoforms of the neurofibromatosis type 1 gene product, neurofibromin, in muscle tissues. Dev Dyn 1995;202:302-311.
    • (1995) Dev Dyn , vol.202 , pp. 302-311
    • Gutmann, D.H.1    Geist, R.T.2    Rose, K.3    Wright, D.E.4
  • 29
    • 0037014663 scopus 로고    scopus 로고
    • Quantification of NF1 transcripts reveals novel highly expressed splice variants
    • DOI 10.1016/S0014-5793(02)02887-9, PII S0014579302028879
    • Van Den Broucke I, Van De Sompele J, De Paepe A, Messiaen L: Quantification of NF1 transcripts reveals novel highly expressed splice variants. FEBS Lett 2002;522:71-76. (Pubitemid 34722500)
    • (2002) FEBS Letters , vol.522 , Issue.1-3 , pp. 71-76
    • Vandenbroucke, I.1    Vandesompele, J.2    De Paepe, A.3    Messiaen, L.4
  • 33
    • 0033011733 scopus 로고    scopus 로고
    • Posttranslational regulation of neurofibromin content in melanocytes of neurofibromatosis type 1 patients
    • DOI 10.1007/s004030050415
    • Kaufmann D, Bartelt B, Hoffmeyer S, Muller R: Posttranslational regulation of neurofibromin content in melanocytes of neurofibromatosis type 1. Arch Dermatol Res 1999;291:312-317. (Pubitemid 29281319)
    • (1999) Archives of Dermatological Research , vol.291 , Issue.6 , pp. 312-317
    • Kaufmann, D.1    Bartelt, B.2    Hoffmeyer, S.3    Muller, R.4
  • 34
    • 16844365150 scopus 로고    scopus 로고
    • The effect of extracellular calcium concentration on calcium-mediated cell signaling in NF1 tumor suppressor-deficient keratinocytes
    • DOI 10.1007/s00403-004-0538-4
    • Korkiamaki T, Yla-Outinen H, Leinonen P, Koivunen J, Peltonen J: The effect of extracellular calcium concentration on calcium-mediated cell signaling in NF1 tumor suppressor-deficient keratinocytes. Arch Dermatol Res 2005;296:465-472. (Pubitemid 40487358)
    • (2005) Archives of Dermatological Research , vol.296 , Issue.10 , pp. 465-472
    • Korkiamaki, T.1    Yla-Outinen, H.2    Leinonen, P.3    Koivunen, J.4    Peltonen, J.5
  • 35
    • 32244437769 scopus 로고    scopus 로고
    • Phosphorylation of neurofibromin by PKC is a possible molecular switch in EGF receptor signaling in neural cells
    • DOI 10.1038/sj.onc.1209113, PII 1209113
    • Mangoura D, Sun Y, Li C, Singh D, Gutmann DH, et al: Phosphorylation of neurofibromin by PKC is a possible molecular switch in EGF receptor signaling in neural cells. Oncogene 2006;25:735-745. (Pubitemid 43214700)
    • (2006) Oncogene , vol.25 , Issue.5 , pp. 735-745
    • Mangoura, D.1    Sun, Y.2    Li, C.3    Singh, D.4    Gutmann, D.H.5    Flores, A.6    Ahmed, M.7    Vallianatos, G.8
  • 36
    • 0029112255 scopus 로고
    • Neurofibromin: Expression by normal human keratinocytes in vivo and in vitro and in epidermal malignancies
    • Hermonen J, Hirvonen O, Yla-Outinen H, Lakkakorpi J, Bjorkstrand AS, et al: Neurofibromin: expression by normal human keratinocytes in vivo and in vitro and in epidermal malignancies. Lab Invest 1995;73:221-228.
    • (1995) Lab Invest , vol.73 , pp. 221-228
    • Hermonen, J.1    Hirvonen, O.2    Yla-Outinen, H.3    Lakkakorpi, J.4    Bjorkstrand, A.S.5
  • 37
    • 0029897881 scopus 로고    scopus 로고
    • Phosphorylation of neurofibromatosis type 1 gene product (neurofibromin) by cAMP-dependent protein kinase
    • DOI 10.1016/0014-5793(96)00137-8
    • Izawa I, Tamaki N, Saya H: Phosphorylation of neurofibromatosis type 1 gene product (neurofibromin) by cAMP-dependent protein kinase. FEBS Lett 1996;382:53-59. (Pubitemid 26092233)
    • (1996) FEBS Letters , vol.382 , Issue.1-2 , pp. 53-59
    • Izawa, I.1    Tamaki, N.2    Saya, H.3
  • 39
    • 0025244911 scopus 로고
    • The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae
    • Xu GF, Lin B, Tanaka K, Dunn D, Wood D, et al: The catalytic domain of neurofibromatosis type I gene product stimulates ras GTPase and complements ira mutants of S. cerevisae. Cell 1990;63:835-841. (Pubitemid 120035056)
    • (1990) Cell , vol.63 , Issue.4 , pp. 835-841
    • Xu, G.1    Lin, B.2    Tanaka, K.3    Dunn, D.4    Wood, D.5    Gesteland, R.6    White, R.7    Weiss, R.8    Tamanoi, F.9
  • 40
    • 0035371069 scopus 로고    scopus 로고
    • Bipartite interaction between neurofibromatosis type I protein (Neurofibromin) and syndecan transmembrane heparan sulfate proteoglycans
    • Hsueh YP, Roberts AM, Volta M, Sheng M, Roberts RG: Bipartite interaction between neurofibromatosis type I protein (neurofibromin) and syndecan transmembrane heparan sulfate proteoglycans. J Neurosci 2001;21:3764-3770. (Pubitemid 32466468)
    • (2001) Journal of Neuroscience , vol.21 , Issue.11 , pp. 3764-3770
    • Hsueh, Y.-P.1    Roberts, A.M.2    Volta, M.3    Sheng, M.4    Roberts, R.G.5
  • 41
    • 0027310225 scopus 로고
    • Characterization of full-length neurofibromin: Tubulin inhibits Ras GAP activity
    • Bollag G, McCormick F, Clark R: Characterization of full-length neurofibromin: tubulin inhibits Ras-GAP activity. EMBO J 1993;12:1923-1927. (Pubitemid 23157708)
    • (1993) EMBO Journal , vol.12 , Issue.5 , pp. 1923-1927
    • Bollag, G.1    McCormick, F.2    Clark, R.3
  • 44
    • 0035944533 scopus 로고    scopus 로고
    • Differential localization of the neurofibromatosis 1 (NF1) gene product, neurofibromin, with the F-actin or microtubule cytoskeleton during differentiation of telencephalic neurons
    • DOI 10.1016/S0165-3806(01)00190-0, PII S0165380601001900
    • Li C, Cheng Y, Gutmann DA, Mangoura D: Differential localization of the neurofibromatosis 1 (NF1) gene product, neurofibromin, with the F-actin or microtubule cytoskeleton during differentiation of telencephalic neurons. Brain Res Dev Brain Res 2001;130:231-248. (Pubitemid 33000087)
    • (2001) Developmental Brain Research , vol.130 , Issue.2 , pp. 231-248
    • Li, C.1    Cheng, Y.2    Gutmann, D.A.3    Mangoura, D.4
  • 45
  • 46
    • 0027460345 scopus 로고
    • Neurofibromin, a predominantly neuronal GTPase activating protein in the adult, is ubiquitously expressed during development
    • Daston MM, Ratner N: Neurofibromin, a predominantly neuronal GTPase activating protein in the adult, is ubiquitously expressed during development. Dev Dyn 1992;195:216-226. (Pubitemid 23119299)
    • (1993) Developmental Dynamics , vol.195 , Issue.3 , pp. 216-226
    • Daston, M.M.1    Ratner, N.2
  • 47
    • 0028266450 scopus 로고
    • Differential expression and tissue distribution of type I and type II neurofibromins during mouse fetal development
    • DOI 10.1006/dbio.1994.1052
    • Huynh DP, Nechiporuk T, Pulst SM: Differential expression and tissue distribution of type I and type II neurofibromins during mouse fetal development. Dev Biol 1994;161:538-551. (Pubitemid 24077422)
    • (1994) Developmental Biology , vol.161 , Issue.2 , pp. 538-551
    • Huynh, D.P.1    Nechiporuk, T.2    Pulstl, S.M.3
  • 49
    • 2942527028 scopus 로고    scopus 로고
    • Functional expression of NF1 tumor suppressor protein: Association with keratin intermediate filaments during the early development of human epidermis
    • Malminen M, Peltonen S, Koivunen J, Peltonen J: Functional expression of NF1 tumor suppressor protein: association with keratin intermediate filaments during the early development of human epidermis. BMC Dermatol 2002;2:10.
    • (2002) BMC Dermatol , vol.2 , pp. 10
    • Malminen, M.1    Peltonen, S.2    Koivunen, J.3    Peltonen, J.4
  • 50
    • 0036084404 scopus 로고    scopus 로고
    • Altered calcium-mediated cell signaling in keratinocytes cultured from patients with neurofibromatosis type 1
    • Korkiamäki T, Ylä-Outinen H, Koivunen J, Karvonen S-L, Peltonen J: Altered calcium mediated cell signaling in keratinocytes cultured from patients with neurofibromatosis type 1. Am J Pathol 2002;160:1981-1990. (Pubitemid 34663391)
    • (2002) American Journal of Pathology , vol.160 , Issue.6 , pp. 1981-1990
    • Korkiamaki, T.1    Yla-Outinen, H.2    Koivunen, J.3    Karvonen, S.-L.4    Peltonen, J.5
  • 51
    • 33646158223 scopus 로고    scopus 로고
    • Nf1 haploinsufficiency augments angiogenesis
    • Wu M, Wallace MR, Muir D: Nf1 haploinsufficiency augments angiogenesis. Oncogene 2006;25:2297-2303.
    • (2006) Oncogene , vol.25 , pp. 2297-2303
    • Wu, M.1    Wallace, M.R.2    Muir, D.3
  • 52
    • 0033527061 scopus 로고    scopus 로고
    • Haploinsufficiency for the neurofibromatosis 1 (NF1) tumor suppressor results in increased astrocyte proliferation
    • DOI 10.1038/sj.onc.1202829
    • Gutmann DH, Loehr A, Zhang Y, Kim J, Henkemeyer M, Cashen A: Haploinsufficiency for the neurofibromatosis 1 (NF1) tumor suppressor results in increased astrocyte proliferation. Oncogene 1999;18:4450-4459. (Pubitemid 29396653)
    • (1999) Oncogene , vol.18 , Issue.31 , pp. 4450-4459
    • Gutmann, D.H.1    Loehr, A.2    Zhang, Y.3    Kim, J.4    Henkemeyer, M.5    Cashen, A.6
  • 57
    • 20044369031 scopus 로고    scopus 로고
    • Targeting neovascular pericytes in neurofibromatosis type 1
    • DOI 10.1007/s10456-004-6643-3
    • Ozerdem U: Targeting neovascular pericytes in neurofibromatosis type 1. Angiogenesis 2004;7:307-311. (Pubitemid 40767932)
    • (2004) Angiogenesis , vol.7 , Issue.4 , pp. 307-311
    • Ozerdem, U.1
  • 59
    • 0025290181 scopus 로고
    • Angiogenic and invasive properties of neurofibroma Schwann cells
    • Sheela S, Riccardi VM, Ratner N: Angiogenic and invasive properties of neurofibroma Schwann cells. J Cell Biol 1990;111:645-653.
    • (1990) J Cell Biol , vol.111 , pp. 645-653
    • Sheela, S.1    Riccardi, V.M.2    Ratner, N.3
  • 60
    • 0035804219 scopus 로고    scopus 로고
    • The angiogenic factor midkine is aberrantly expressed in NF1-deficient Schwann cells and is a mitogen for neurofibroma-derived cells
    • DOI 10.1038/sj.onc.1204026
    • Mashour GA, Ratner N, Khan GA, Wang HL, Martuza RL, Kurtz A: The angiogenic factor midkine is aberrantly expressed in NF1-deficient Schwann cells and is a mitogen for neurofibromaderived cells. Oncogene 2001;20:97-105. (Pubitemid 32142342)
    • (2001) Oncogene , vol.20 , Issue.1 , pp. 97-105
    • Mashour, G.A.1    Ratner, N.2    Khan, G.A.3    Wang, H.-L.4    Martuza, R.L.5    Kurtz, A.6
  • 61
    • 34548433102 scopus 로고    scopus 로고
    • The genetic predisposition to and histogenesis of neurofibromas and neurofibrosarcoma in neurofibromatosis type 1
    • Riccardi VM: The genetic predisposition to and histogenesis of neurofibromas and neurofibrosarcoma in neurofibromatosis type 1. Neurosurg Focus 2007;22:E31-11.
    • (2007) Neurosurg Focus , vol.22
    • Riccardi, V.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.