메뉴 건너뛰기




Volumn 7, Issue 4, 2004, Pages 307-311

Targeting neovascular pericytes in neurofibromatosis type 1

Author keywords

Angiogenesis; Endothelium; Mural cell; Neurofibromatosis; NF1; NG2; Pericyte; Type 1

Indexed keywords

IMMUNOGLOBULIN; NEUTRALIZING ANTIBODY; PROTEIN ANTIBODY; PROTEOGLYCAN;

EID: 20044369031     PISSN: 09696970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10456-004-6643-3     Document Type: Article
Times cited : (42)

References (36)
  • 1
    • 0033229939 scopus 로고    scopus 로고
    • Inhibition of angiogenesis by blocking activation of the vascular endothelial growth factor receptor 2 leads to decreased growth of neurogenic sarcomas
    • 21
    • L Angelov B Salhia L. Roncari 1999 Inhibition of angiogenesis by blocking activation of the vascular endothelial growth factor receptor 2 leads to decreased growth of neurogenic sarcomas Cancer Res 59 21 5536 5541
    • (1999) Cancer Res , vol.59 , pp. 5536-5541
    • Angelov, L.1    Salhia, B.2    Roncari, L.3
  • 2
    • 0031870437 scopus 로고    scopus 로고
    • Neurofibromatosis type 1: Piecing the puzzle together
    • 3
    • MM Feldkamp DH Gutmann A. Guha 1998 Neurofibromatosis type 1: Piecing the puzzle together Can J Neurol Sci 25 3 181 191
    • (1998) Can J Neurol Sci , vol.25 , pp. 181-191
    • Feldkamp, M.M.1    Gutmann, D.H.2    Guha, A.3
  • 3
    • 0030663479 scopus 로고    scopus 로고
    • Cell-cell interactions in vessel assembly: A model for the fundamentals of vascular remodelling
    • 3
    • KK Hirschi SA Rohovsky PA. D'Amore 1997 Cell-cell interactions in vessel assembly: A model for the fundamentals of vascular remodelling Transpl Immunol 5 3 177 178
    • (1997) Transpl Immunol , vol.5 , pp. 177-178
    • Hirschi, K.K.1    Rohovsky, S.A.2    D'Amore, P.A.3
  • 4
    • 0038376001 scopus 로고    scopus 로고
    • Imaging of angiogenesis: From microscope to clinic
    • 6
    • DM McDonald PL. Choyke 2003 Imaging of angiogenesis: From microscope to clinic Nat Med 9 6 713 25
    • (2003) Nat Med , vol.9 , pp. 713-25
    • McDonald, D.M.1    Choyke, P.L.2
  • 5
    • 1942504107 scopus 로고    scopus 로고
    • Early contribution of pericytes to angiogenic sprouting and tube formation
    • 3
    • U Ozerdem WB. Stallcup 2003 Early contribution of pericytes to angiogenic sprouting and tube formation Angiogenesis 6 3 241 249
    • (2003) Angiogenesis , vol.6 , pp. 241-249
    • Ozerdem, U.1    Stallcup, W.B.2
  • 6
    • 0036354793 scopus 로고    scopus 로고
    • NG2 proteoglycan expression by pericytes in pathological microvasculature
    • 1
    • U Ozerdem E Monosov WB. Stallcup 2002 NG2 proteoglycan expression by pericytes in pathological microvasculature Microvasc Res 63 1 129 134
    • (2002) Microvasc Res , vol.63 , pp. 129-134
    • Ozerdem, U.1    Monosov, E.2    Stallcup, W.B.3
  • 7
    • 0034796499 scopus 로고    scopus 로고
    • NG2 proteoglycan is expressed exclusively by mural cells during vascular morphogenesis
    • 2
    • U Ozerdem KA Grako K. Dahlin-Huppe 2001 NG2 proteoglycan is expressed exclusively by mural cells during vascular morphogenesis Dev Dyn 222 2 218 227
    • (2001) Dev Dyn , vol.222 , pp. 218-227
    • Ozerdem, U.1    Grako, K.A.2    Dahlin-Huppe, K.3
  • 8
    • 0029240729 scopus 로고
    • Expression of the neurofibromatosis I gene product, neurofibromin, in blood vessel endothelial cells and smooth muscle
    • 1
    • KK Norton J Xu DH. Gutmann 1995 Expression of the neurofibromatosis I gene product, neurofibromin, in blood vessel endothelial cells and smooth muscle Neurobiol Dis 2 1 13 21
    • (1995) Neurobiol Dis , vol.2 , pp. 13-21
    • Norton, K.K.1    Xu, J.2    Gutmann, D.H.3
  • 9
    • 0033670127 scopus 로고    scopus 로고
    • Insights into the pathogenesis of neurofibromatosis 1 vasculopathy
    • 5
    • SJ Hamilton JM. Friedman 2000 Insights into the pathogenesis of neurofibromatosis 1 vasculopathy Clin Genet 58 5 341 344
    • (2000) Clin Genet , vol.58 , pp. 341-344
    • Hamilton, S.J.1    Friedman, J.M.2
  • 10
    • 0037229065 scopus 로고    scopus 로고
    • Nf1 has an essential role in endothelial cells
    • 1
    • AD Gitler Y Zhu FA. Ismat 2003 Nf1 has an essential role in endothelial cells Nat Genet 33 1 75 79
    • (2003) Nat Genet , vol.33 , pp. 75-79
    • Gitler, A.D.1    Zhu, Y.2    Ismat, F.A.3
  • 11
    • 0018678899 scopus 로고
    • Angiogenesis in the mouse cornea
    • 4413
    • V Muthukkaruppan R. Auerbach 1979 Angiogenesis in the mouse cornea Science 205 4413 1416 1418
    • (1979) Science , vol.205 , pp. 1416-1418
    • Muthukkaruppan, V.1    Auerbach, R.2
  • 13
    • 12444253931 scopus 로고    scopus 로고
    • Pathological angiogenesis is reduced by targeting pericytes via the NG2 proteoglycan
    • 3
    • U Ozerdem WB. Stallcup 2004 Pathological angiogenesis is reduced by targeting pericytes via the NG2 proteoglycan Angiogenesis 7 3 269 276
    • (2004) Angiogenesis , vol.7 , pp. 269-276
    • Ozerdem, U.1    Stallcup, W.B.2
  • 14
    • 0031171663 scopus 로고    scopus 로고
    • Effects of thalidomide and related metabolites in a mouse corneal model of neovascularization
    • 6
    • BM Kenyon F Browne RJ. D'Amato 1997 Effects of thalidomide and related metabolites in a mouse corneal model of neovascularization Exp Eye Res 64 6 971 978
    • (1997) Exp Eye Res , vol.64 , pp. 971-978
    • Kenyon, B.M.1    Browne, F.2    D'Amato, R.J.3
  • 15
    • 0028349997 scopus 로고
    • Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues
    • 9
    • CI Brannan AS Perkins KS. Vogel 1994 Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues Genes Dev 8 9 1019 1029
    • (1994) Genes Dev , vol.8 , pp. 1019-1029
    • Brannan, C.I.1    Perkins, A.S.2    Vogel, K.S.3
  • 18
    • 0034161361 scopus 로고    scopus 로고
    • Vasculogenesis in the day 6.5 to 9.5 mouse embryo
    • 5
    • CJ Drake PA. Fleming 2000 Vasculogenesis in the day 6.5 to 9.5 mouse embryo Blood 95 5 1671 1679
    • (2000) Blood , vol.95 , pp. 1671-1679
    • Drake, C.J.1    Fleming, P.A.2
  • 19
    • 0034687663 scopus 로고    scopus 로고
    • Mosaic blood vessels in tumors: Frequency of cancer cells in contact with flowing blood
    • 26
    • YS Chang E di Tomaso DM McDonald 2000 Mosaic blood vessels in tumors: Frequency of cancer cells in contact with flowing blood Proc Natl Acad Sci USA 97 26 14608 14613
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 14608-14613
    • Chang, Y.S.1    Di Tomaso, E.2    McDonald, D.M.3
  • 20
    • 0242405617 scopus 로고    scopus 로고
    • Endothelial-pericyte interactions in angiogenesis
    • 1
    • H Gerhardt C. Betsholtz 2003 Endothelial-pericyte interactions in angiogenesis Cell Tissue Res 314 1 15 23
    • (2003) Cell Tissue Res , vol.314 , pp. 15-23
    • Gerhardt, H.1    Betsholtz, C.2
  • 21
    • 4644295385 scopus 로고    scopus 로고
    • Adult bone marrow-derived cells recruited during angiogenesis comprise precursors for periendothelial vascular mural cells
    • 7
    • I Rajantie M Ilmonen A. Alminaite 2004 Adult bone marrow-derived cells recruited during angiogenesis comprise precursors for periendothelial vascular mural cells Blood 104 7 2084 2086
    • (2004) Blood , vol.104 , pp. 2084-2086
    • Rajantie, I.1    Ilmonen, M.2    Alminaite, A.3
  • 22
    • 0020823261 scopus 로고
    • Flow cytometric measurement of total DNA content and incorporated bromodeoxyuridine
    • 18
    • F Dolbeare H Gratzner MG Pallavicini JW. Gray 1983 Flow cytometric measurement of total DNA content and incorporated bromodeoxyuridine Proc Natl Acad Sci USA 80 18 5573 5577
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 5573-5577
    • Dolbeare, F.1    Gratzner, H.2    Pallavicini, M.G.3    Gray, J.W.4
  • 23
    • 84990602541 scopus 로고
    • Cell-cycle analysis using a monoclonal antibody to BrdUrd
    • 4
    • PN Dean F Dolbeare H. Gratzner 1984 Cell-cycle analysis using a monoclonal antibody to BrdUrd Cell Tissue Kinet 17 4 427 436
    • (1984) Cell Tissue Kinet , vol.17 , pp. 427-436
    • Dean, P.N.1    Dolbeare, F.2    Gratzner, H.3
  • 24
    • 0024369746 scopus 로고
    • Bromodeoxyuridine immunohistochemical determination of the lengths of the cell cycle and the DNA-synthetic phase for an anatomically defined population
    • 3
    • RS Nowakowski SB Lewin MW. Miller 1989 Bromodeoxyuridine immunohistochemical determination of the lengths of the cell cycle and the DNA-synthetic phase for an anatomically defined population. J Neurocytol 18 3 311 318
    • (1989) J Neurocytol , vol.18 , pp. 311-318
    • Nowakowski, R.S.1    Lewin, S.B.2    Miller, M.W.3
  • 25
    • 0034976643 scopus 로고    scopus 로고
    • Time course of endothelial cell proliferation and microvascular remodeling in chronic inflammation
    • 6
    • T Ezaki P Baluk G. Thurston 2001 Time course of endothelial cell proliferation and microvascular remodeling in chronic inflammation Am J Pathol 158 6 2043 2055
    • (2001) Am J Pathol , vol.158 , pp. 2043-2055
    • Ezaki, T.1    Baluk, P.2    Thurston, G.3
  • 26
    • 0030756325 scopus 로고    scopus 로고
    • Pericyte loss and microaneurysm formation in PDGF-B-deficient mice
    • 5323
    • P Lindahl BR Johansson P Leveen C. Betsholtz 1997 Pericyte loss and microaneurysm formation in PDGF-B-deficient mice Science 277 5323 242 245
    • (1997) Science , vol.277 , pp. 242-245
    • Lindahl, P.1    Johansson, B.R.2    Leveen, P.3    Betsholtz, C.4
  • 28
    • 0029240729 scopus 로고
    • Expression of the neurofibromatosis I gene product, neurofibromin, in blood vessel endothelial cells and smooth muscle
    • 1
    • KK Norton J Xu DH. Gutmann 1995 Expression of the neurofibromatosis I gene product, neurofibromin, in blood vessel endothelial cells and smooth muscle Neurobiol Dis 2 1 13 21
    • (1995) Neurobiol Dis , vol.2 , pp. 13-21
    • Norton, K.K.1    Xu, J.2    Gutmann, D.H.3
  • 29
    • 0035894746 scopus 로고    scopus 로고
    • Heterozygosity for the neurofibromatosis 1 (NF1) tumor suppressor results in abnormalities in cell attachment, spreading and motility in astrocytes
    • 26
    • DH Gutmann YL Wu NM. Hedrick 2001 Heterozygosity for the neurofibromatosis 1 (NF1) tumor suppressor results in abnormalities in cell attachment, spreading and motility in astrocytes Hum Mol Genet 10 26 3009 3016
    • (2001) Hum Mol Genet , vol.10 , pp. 3009-3016
    • Gutmann, D.H.1    Wu, Y.L.2    Hedrick, N.M.3
  • 30
    • 0346059618 scopus 로고    scopus 로고
    • Optic nerve glioma in mice requires astrocyte Nf1 gene inactivation and Nf1 brain heterozygosity
    • 24
    • ML Bajenaru MR Hernandez A Perry 2003 Optic nerve glioma in mice requires astrocyte Nf1 gene inactivation and Nf1 brain heterozygosity Cancer Res 63 24 8573 8577
    • (2003) Cancer Res , vol.63 , pp. 8573-8577
    • Bajenaru, M.L.1    Hernandez, M.R.2    Perry, A.3
  • 31
    • 0037111634 scopus 로고    scopus 로고
    • Lymphoproliferative defects in mice lacking the expression of neurofibromin: Functional and biochemical consequences of Nf1 deficiency in T-cell development and function
    • 10
    • DA Ingram L Zhang J. McCarthy 2002 Lymphoproliferative defects in mice lacking the expression of neurofibromin: Functional and biochemical consequences of Nf1 deficiency in T-cell development and function Blood 100 10 3656 3662
    • (2002) Blood , vol.100 , pp. 3656-3662
    • Ingram, D.A.1    Zhang, L.2    McCarthy, J.3
  • 32
    • 0041624494 scopus 로고    scopus 로고
    • Aberrant growth and differentiation of oligodendrocyte progenitors in neurofibromatosis type 1 mutants
    • 18
    • MR Bennett TA Rizvi S. Karyala 2003 Aberrant growth and differentiation of oligodendrocyte progenitors in neurofibromatosis type 1 mutants J Neurosci 23 18 7207 7217
    • (2003) J Neurosci , vol.23 , pp. 7207-7217
    • Bennett, M.R.1    Rizvi, T.A.2    Karyala, S.3
  • 33
    • 0035038659 scopus 로고    scopus 로고
    • The cephalic neural crest provides pericytes and smooth muscle cells to all blood vessels of the face and forebrain
    • 7
    • HC Etchevers C Vincent NM Le Douarin GF. Couly 2001 The cephalic neural crest provides pericytes and smooth muscle cells to all blood vessels of the face and forebrain Development 128 7 1059 1068
    • (2001) Development , vol.128 , pp. 1059-1068
    • Etchevers, H.C.1    Vincent, C.2    Le Douarin, N.M.3    Couly, G.F.4
  • 34
    • 0036132050 scopus 로고    scopus 로고
    • Neuroectodermal origin of brain pericytes and vascular smooth muscle cells
    • 1
    • J Korn B Christ H. Kurz 2002 Neuroectodermal origin of brain pericytes and vascular smooth muscle cells J Comp Neurol 442 1 78 88
    • (2002) J Comp Neurol , vol.442 , pp. 78-88
    • Korn, J.1    Christ, B.2    Kurz, H.3
  • 35
    • 0038476608 scopus 로고    scopus 로고
    • Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors
    • 9
    • G Bergers S Song N Meyer-Morse 2003 Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors J Clin Invest 111 9 1287 1295
    • (2003) J Clin Invest , vol.111 , pp. 1287-1295
    • Bergers, G.1    Song, S.2    Meyer-Morse, N.3
  • 36
    • 0038665460 scopus 로고    scopus 로고
    • Double target for tumor mass destruction
    • 9
    • P Saharinen K. Alitalo 2003 Double target for tumor mass destruction J Clin Invest 111 9 1277 80
    • (2003) J Clin Invest , vol.111 , pp. 1277-80
    • Saharinen, P.1    Alitalo, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.