Effects of a polar amino acid substitution on helix formation and aggregate size along the detergent-induced peptide folding pathway

Biochimica et Biophysica Acta - Biomembranes

Volumn 1828, Issue 2, 2013, Pages 373-381

  Alvares, Rohan D A ^a   Tulumello, David V ^b,c   MacDonald, Peter M ^a   Deber, Charles M ^b,c   Prosser, R Scott ^a,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Detergent peptide aggregate size; Detergent protein interaction; Membrane protein denaturation; Membrane protein folding; Pulsed field gradient diffusion; Transmembrane peptide NMR

Indexed keywords

DETERGENT; DODECYL SULFATE SODIUM; DODECYLPHOSPHORYLCHOLINE; POLYLYSINE;

ALPHA HELIX; AMINO ACID SUBSTITUTION; AQUEOUS SOLUTION; ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; CRITICAL MICELLE CONCENTRATION; DIFFUSION; MEMBRANE STRUCTURE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN FOLDING; PROTEIN LIPID INTERACTION; PROTEIN SECONDARY STRUCTURE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO ACIDS; CIRCULAR DICHROISM; DETERGENTS; DIFFUSION; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; LIPID BILAYERS; LYSINE; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDES; PHOSPHORYLCHOLINE; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; SODIUM DODECYL SULFATE;

EID: 84870176720     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2012.09.024     Document Type: Article

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