Structural basis for misfolding at a disease phenotypic position in CFTR: Comparison of TM3/4 helix-loop-helix constructs with TM4 peptides

Biochimica et Biophysica Acta - Biomembranes

Volumn 1818, Issue 1, 2012, Pages 49-54

  Mulvihill, Cory M ^a,b   Deber, Charles M ^a,b  

^a HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Cystic fibrosis transmembrane conductance regulator (CFTR); Hydropathy; Membrane protein; SDS PAGE

Indexed keywords

AMINO ACID; HELIX LOOP HELIX PROTEIN; MEMBRANE PROTEIN; TRANSMEMBRANE CONDUCTANCE REGULATOR; TRANSMEMBRANE CONDUCTANCE REGULATOR 3; TRANSMEMBRANE CONDUCTANCE REGULATOR 4; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BIOPHYSICS; CIRCULAR DICHROISM; CONTROLLED STUDY; GEL PERMEATION CHROMATOGRAPHY; HYDROPHOBICITY; MOLECULAR LIBRARY; PHENOTYPIC VARIATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; AMINO ACIDS; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, REVERSE-PHASE; CIRCULAR DICHROISM; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENOMIC LIBRARY; HELIX-TURN-HELIX MOTIFS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; ION TRANSPORT; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDES; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; SODIUM DODECYL SULFATE;

EID: 80054872799     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2011.09.027     Document Type: Article

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