KU-32, a novel drug for diabetic neuropathy, is safe for human islets and improves in vitro insulin secretion and viability

Experimental Diabetes Research

Volumn 2012, Issue , 2012, Pages

  Farmer, Kevin ^a   Williams, S Janette ^b   Novikova, Lesya ^b   Ramachandran, Karthik ^b   Rawal, Sonia ^b   Blagg, Brian S J ^a   Dobrowsky, Rick ^a   Stehno Bittel, Lisa ^b  

^a UNIVERSITY OF KANSAS   (United States)

^b UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HEAT SHOCK PROTEIN 90 INHIBITOR; INSULIN; KU 32; NEUROPROTECTIVE AGENT; UNCLASSIFIED DRUG; DRUG DERIVATIVE; HEAT SHOCK PROTEIN 90; KU 32 COMPOUND; KU-32 COMPOUND; NOVOBIOCIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL VIABILITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DIABETIC NEUROPATHY; DRUG EFFICACY; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN TISSUE; IN VITRO STUDY; INSULIN BLOOD LEVEL; INSULIN RELEASE; MALE; MOUSE; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; ANIMAL; BLOOD; CELL SURVIVAL; DISEASE MODEL; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; MIDDLE AGED; NON INSULIN DEPENDENT DIABETES MELLITUS; PATHOLOGY; SECRETION (PROCESS); TIME; TISSUE CULTURE TECHNIQUE;

ADULT; ANIMALS; APOPTOSIS; BLOOD GLUCOSE; CELL SURVIVAL; DIABETES MELLITUS, TYPE 2; DIABETIC NEUROPATHIES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HSP90 HEAT-SHOCK PROTEINS; HUMANS; INSULIN; ISLETS OF LANGERHANS; MALE; MICE; MICROSCOPY, CONFOCAL; MIDDLE AGED; NEUROPROTECTIVE AGENTS; NOVOBIOCIN; TIME FACTORS; TISSUE CULTURE TECHNIQUES;

EID: 84870168696     PISSN: 16875214     EISSN: 16875303     Source Type: Journal    
DOI: 10.1155/2012/671673     Document Type: Article

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