Neuroprotective activity and evaluation of Hsp90 inhibitors in an immortalized neuronal cell line

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 4, 2009, Pages 1709-1715

  Lu, Yuanming ^a   Ansar, Sabah ^a   Michaelis, Mary L ^a   Blagg, Brian S J ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

Geldanamycin; Hsp90; Neuroprotection; Novobiocin

Indexed keywords

AMYLOID BETA PROTEIN[25-35]; CELASTROL; EPIGALLOCATECHIN GALLATE; GEDUNIN; HEAT SHOCK PROTEIN 90; HEAT SHOCK PROTEIN 90 INHIBITOR; LACTATE DEHYDROGENASE; NOVOBIOCIN; NOVOBIOCIN DERIVATIVE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; ENZYME RELEASE; HUMAN; HUMAN CELL; NERVE CELL CULTURE; NERVE CELL DIFFERENTIATION; NEUROPROTECTION;

CELL DEATH; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HSP90 HEAT-SHOCK PROTEINS; HUMANS; MODELS, NEUROLOGICAL; NEURONS; NEUROPROTECTIVE AGENTS; NOVOBIOCIN;

EID: 60049098351     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.12.047     Document Type: Article

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