Insight into the antimicrobial activities of coprisin isolated from the dung beetle, Copris tripartitus, revealed by structure-activity relationships

Biochimica et Biophysica Acta - Biomembranes

Volumn 1828, Issue 2, 2013, Pages 271-283

  Lee, Eunjung ^a   Kim, Jin Kyoung ^a   Shin, Soyoung ^a   Jeong, Ki Woong ^a   Shin, Areum ^a   Lee, Juneyoung ^b   Lee, Dong Gun ^b   Hwang, Jae Sam ^c   Kim, Yangmee ^a  

^a Konkuk University   (South Korea)

^b Kyungpook National University   (South Korea)

^c National Institute of Animal Science   (South Korea)

Author keywords

Anti inflammatory activity; Antimicrobial peptide; Insect defensin; NMR; Structure

Indexed keywords

CALCEIN; COPRISIN; DEFENSIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MACROPHAGE INFLAMMATORY PROTEIN 2; MELITTIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ALPHA HELIX; ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ANTIMICROBIAL ACTIVITY; AQUEOUS SOLUTION; ARTICLE; BACILLUS SUBTILIS; BACTERIAL MEMBRANE; BEETLE; BETA SHEET; CELL MEMBRANE DEPOLARIZATION; CELL MEMBRANE PERMEABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; COPRIS TRIPARTITUS; CYTOKINE PRODUCTION; DRUG CYTOTOXICITY; DRUG STRUCTURE; ESCHERICHIA COLI; GENE EXPRESSION; HEMOLYSIS; HUMAN; HUMAN CELL; INNATE IMMUNITY; ISOTHERMAL TITRATION CALORIMETRY; KERATINOCYTE; MACROPHAGE; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHOSPHOLIPID MEMBRANE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN TERTIARY STRUCTURE; PSEUDOMONAS AERUGINOSA; SALMONELLA TYPHIMURIUM; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; STATIC ELECTRICITY; STRUCTURE ACTIVITY RELATION; SURFACE CHARGE;

AMINO ACID SEQUENCE; ANIMALS; ANTI-INFECTIVE AGENTS; BEETLES; CELL LINE; CYTOKINES; HUMANS; INFLAMMATION; INSECT PROTEINS; KERATINOCYTES; LIPOPOLYSACCHARIDES; MACROPHAGES; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MOLECULAR SEQUENCE DATA; NF-KAPPA B; NITRIC OXIDE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PEPTIDES; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; SEQUENCE HOMOLOGY, AMINO ACID; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP; TOLL-LIKE RECEPTOR 4;

BACTERIA (MICROORGANISMS); COLEOPTERA; COPRIS; HEXAPODA; NEGIBACTERIA; POSIBACTERIA; STAPHYLOCOCCUS AUREUS;

EID: 84870152930     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2012.10.028     Document Type: Article

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