Role of the phosphatidylinositol 3-kinase and extracellular signal-regulated kinase pathways in the neuroprotective effects of cilnidipine against hypoxia in a primary culture of cortical neurons

Neurochemistry International

Volumn 61, Issue 7, 2012, Pages 1172-1182

  Kim, Sangjae ^a   Lee, Kyu Yong ^b   Koh, Seong Ho ^b,c   Park, Hyun Hee ^b   Yu, Hyun Jeung ^d   Lee, Young Joo ^b  

^a Department of Neuroscience   (South Korea)

^b Hanyang University Guri Hospital   (South Korea)

^c Hanyang University   (South Korea)

^d Bundang Jesaeng Hospital   (South Korea)

Author keywords

Antioxidant; Calcium channel blocker; Extracellular signal related kinase; Hypoxia; Phosphatidylinositol 3 kinase; Stroke

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; CALCIUM; CILNIDIPINE; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; TRYPAN BLUE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BRAIN NERVE CELL; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL HYPOXIA; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; DRUG EXPOSURE; DRUG MECHANISM; NERVE CELL CULTURE; NEUROPROTECTION; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STRESS;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; BLOTTING, WESTERN; CALCIUM; CELL HYPOXIA; CELLS, CULTURED; CEREBRAL CORTEX; DIHYDROPYRIDINES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; IN SITU NICK-END LABELING; NEUROPROTECTIVE AGENTS; PHOSPHATIDYLINOSITOL 3-KINASES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84870066374     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2012.08.010     Document Type: Article

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