Microcystin-LR promotes melanoma cell invasion and enhances matrix metalloproteinase-2/-9 expression mediated by NF-κB activation

Environmental Science and Technology

Volumn 46, Issue 20, 2012, Pages 11319-11326

  Zhang, Xu Xiang ^a   Fu, Ziyi ^b   Zhang, Zongyao ^a   Miao, Chen ^b   Xu, Pengfei ^b   Wang, Ting ^b   Yang, Liuyan ^a   Cheng, Shupei ^a  

^a NANJING UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ABILITIES; BOYDEN CHAMBER; CANCER CELLS; CULTURE MEDIUM; CYANOBACTERIAL TOXINS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENVIRONMENTAL HEALTH CONCERN; EUTROPHIC LAKES; GELATIN ZYMOGRAPHY; IMMUNOFLUORESCENCE ASSAY; INVASIVENESS; MATRIX METALLOPROTEINASE-2; MATRIX METALLOPROTEINASES; MELANOMA CELLS; MICROCYSTIN-LR; MOLECULAR MECHANISM; NUCLEAR FACTOR KAPPAB; OVER-EXPRESSION; PCR ARRAYS; PROTEIN LEVEL; QUANTITATIVE REAL TIME PCR; TUMOR METASTASIS; WESTERN BLOTTING;

CELL CULTURE; CELLS; CHEMICAL ACTIVATION; DERMATOLOGY; ELECTROPHORETIC MOBILITY; ENZYME INHIBITION; ONCOLOGY; PATHOLOGY; POLYMERASE CHAIN REACTION; TUMORS; WELL STIMULATION;

TOXIC MATERIALS;

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MICROCYSTIN LR;

BIOASSAY; CANCER; CYTOLOGY; EXPERIMENTAL STUDY; GENE EXPRESSION; IMMUNOASSAY; INHIBITOR; MOLECULAR ANALYSIS;

ARTICLE; CELL INVASION; COLLAGENASE 3 GENE; CONTROLLED STUDY; DRUG MECHANISM; GEL MOBILITY SHIFT ASSAY; GELATINASE A GENE; GELATINASE B GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MELANOMA; NUCLEOTIDE SEQUENCE; ONCOGENE; POLYMERASE CHAIN REACTION; PROTEIN BINDING; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ZYMOGRAPHY;

CELL LINE, TUMOR; HARMFUL ALGAL BLOOM; HUMANS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MELANOMA; MICROCYSTINS; NF-KAPPA B; RNA, MESSENGER; WATER POLLUTANTS, CHEMICAL;

CYANOBACTERIA;

EID: 84870050405     PISSN: 0013936X     EISSN: 15205851     Source Type: Journal    
DOI: 10.1021/es3024989     Document Type: Article

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