메뉴 건너뛰기




Volumn 4, Issue 11, 2012, Pages

Pharmacogenomics of chemotherapeutic susceptibility and toxicity

Author keywords

chemotherapeutics; clinical translation; genome wide association studies; International HapMap Project; Pharmacogenomics

Indexed keywords

ANTINEOPLASTIC AGENT; AROMATASE INHIBITOR; CAPECITABINE; CETUXIMAB; CISPLATIN; CYTARABINE; ERLOTINIB; FLUOROURACIL; GEFITINIB; IRINOTECAN; METHOTREXATE; NILOTINIB; PANITUMUMAB; RASBURICASE; TAMOXIFEN; TIOGUANINE; VEMURAFENIB;

EID: 84869890136     PISSN: None     EISSN: 1756994X     Source Type: Journal    
DOI: 10.1186/gm391     Document Type: Review
Times cited : (29)

References (92)
  • 2
    • 40949127393 scopus 로고    scopus 로고
    • How to interpret a genome-wide association study.
    • 10.1001/jama.299.11.1335, 18349094
    • Pearson TA, Manolio TA. How to interpret a genome-wide association study. JAMA 2008, 299:1335-1344. 10.1001/jama.299.11.1335, 18349094.
    • (2008) JAMA , vol.299 , pp. 1335-1344
    • Pearson, T.A.1    Manolio, T.A.2
  • 3
    • 84860448229 scopus 로고    scopus 로고
    • Germline pharmacogenomics in oncology: decoding the patient for targeting therapy.
    • 10.1016/j.molonc.2012.01.005, 22321460
    • O'Donnell PH, Ratain MJ. Germline pharmacogenomics in oncology: decoding the patient for targeting therapy. Mol Oncol 2012, 6:251-259. 10.1016/j.molonc.2012.01.005, 22321460.
    • (2012) Mol Oncol , vol.6 , pp. 251-259
    • O'Donnell, P.H.1    Ratain, M.J.2
  • 14
    • 3042616025 scopus 로고    scopus 로고
    • Heritability and linkage analysis of sensitivity to cisplatin-induced cytotoxicity.
    • 10.1158/0008-5472.CAN-04-0340, 15205351
    • Dolan ME, Newbold KG, Nagasubramanian R, Wu X, Ratain MJ, Cook EH, Badner JA. Heritability and linkage analysis of sensitivity to cisplatin-induced cytotoxicity. Cancer Res 2004, 64:4353-4356. 10.1158/0008-5472.CAN-04-0340, 15205351.
    • (2004) Cancer Res , vol.64 , pp. 4353-4356
    • Dolan, M.E.1    Newbold, K.G.2    Nagasubramanian, R.3    Wu, X.4    Ratain, M.J.5    Cook, E.H.6    Badner, J.A.7
  • 15
    • 33947588763 scopus 로고    scopus 로고
    • Should DPD analysis be required prior to prescribing fluoropyrimidines?.
    • 10.1016/j.ejca.2007.01.030, 17350823
    • Yen JL, McLeod HL. Should DPD analysis be required prior to prescribing fluoropyrimidines?. Eur J Cancer 2007, 43:1011-1016. 10.1016/j.ejca.2007.01.030, 17350823.
    • (2007) Eur J Cancer , vol.43 , pp. 1011-1016
    • Yen, J.L.1    McLeod, H.L.2
  • 16
    • 79960837042 scopus 로고    scopus 로고
    • Chemotherapeutic-induced apoptosis: a phenotype for pharmacogenomics studies.
    • 10.1097/FPC.0b013e3283481967, 3134538, 21642893
    • Wen Y, Gorsic LK, Wheeler HE, Ziliak DM, Huang RS, Dolan ME. Chemotherapeutic-induced apoptosis: a phenotype for pharmacogenomics studies. Pharmacogenet Genomics 2011, 21:476-488. 10.1097/FPC.0b013e3283481967, 3134538, 21642893.
    • (2011) Pharmacogenet Genomics , vol.21 , pp. 476-488
    • Wen, Y.1    Gorsic, L.K.2    Wheeler, H.E.3    Ziliak, D.M.4    Huang, R.S.5    Dolan, M.E.6
  • 17
    • 33847678481 scopus 로고    scopus 로고
    • Pharmacogenomics of cancer chemotherapy-induced toxicity.
    • Miller CR, McLeod HL. Pharmacogenomics of cancer chemotherapy-induced toxicity. J Support Oncol 2007, 5:9-14.
    • (2007) J Support Oncol , vol.5 , pp. 9-14
    • Miller, C.R.1    McLeod, H.L.2
  • 18
    • 77951541774 scopus 로고    scopus 로고
    • Biobanking and pharmacogenomics.
    • 10.2217/pgs.10.13, 20415552
    • McCarty CA, Wilke RA. Biobanking and pharmacogenomics. Pharmacogenomics 2010, 11:637-641. 10.2217/pgs.10.13, 20415552.
    • (2010) Pharmacogenomics , vol.11 , pp. 637-641
    • McCarty, C.A.1    Wilke, R.A.2
  • 19
    • 36549032598 scopus 로고    scopus 로고
    • Avoiding false discoveries in association studies.
    • 10.1007/978-1-59745-389-9_14, 17984547
    • Sabatti C. Avoiding false discoveries in association studies. Methods Mol Biol 2007, 376:195-211. 10.1007/978-1-59745-389-9_14, 17984547.
    • (2007) Methods Mol Biol , vol.376 , pp. 195-211
    • Sabatti, C.1
  • 20
    • 46949090611 scopus 로고    scopus 로고
    • Controlling false discoveries in genetic studies.
    • 10.1002/ajmg.b.30650, 18092307
    • van den Oord EJ. Controlling false discoveries in genetic studies. Am J Med Genet B Neuropsychiatr Genet 2008, 147B:637-644. 10.1002/ajmg.b.30650, 18092307.
    • (2008) Am J Med Genet B Neuropsychiatr Genet , vol.147 B , pp. 637-644
    • van den Oord, E.J.1
  • 21
    • 4043179101 scopus 로고    scopus 로고
    • Drug interactions in oncology.
    • 10.1016/S1470-2045(04)01528-1, 15288238
    • Beijnen JH, Schellens JH. Drug interactions in oncology. Lancet Oncol 2004, 5:489-496. 10.1016/S1470-2045(04)01528-1, 15288238.
    • (2004) Lancet Oncol , vol.5 , pp. 489-496
    • Beijnen, J.H.1    Schellens, J.H.2
  • 22
    • 0023119219 scopus 로고
    • Thiopurine pharmacogenetics in leukemia: correlation of erythrocyte thiopurine methyltransferase activity and 6-thioguanine nucleotide concentrations.
    • 10.1038/clpt.1987.4, 3467886
    • Lennard L, Van Loon JA, Lilleyman JS, Weinshilboum RM. Thiopurine pharmacogenetics in leukemia: correlation of erythrocyte thiopurine methyltransferase activity and 6-thioguanine nucleotide concentrations. Clin Pharmacol Ther 1987, 41:18-25. 10.1038/clpt.1987.4, 3467886.
    • (1987) Clin Pharmacol Ther , vol.41 , pp. 18-25
    • Lennard, L.1    Van Loon, J.A.2    Lilleyman, J.S.3    Weinshilboum, R.M.4
  • 23
    • 30444437486 scopus 로고    scopus 로고
    • Treatment of acute lymphoblastic leukemia.
    • 10.1056/NEJMra052603, 16407512
    • Pui CH, Evans WE. Treatment of acute lymphoblastic leukemia. N Engl J Med 2006, 354:166-178. 10.1056/NEJMra052603, 16407512.
    • (2006) N Engl J Med , vol.354 , pp. 166-178
    • Pui, C.H.1    Evans, W.E.2
  • 25
    • 79951809968 scopus 로고    scopus 로고
    • Clinical Pharmacogenetics Implementation Consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing.
    • 10.1038/clpt.2010.320, 3098761,3098761, 21270794, Clinical Pharmacogenetics Implementation Consortium
    • Relling MV, Gardner EE, Sandborn WJ, Schmiegelow K, Pui CH, Yee SW, Stein CM, Carrillo M, Evans WE, Klein TE, . Clinical Pharmacogenetics Implementation Consortium Clinical Pharmacogenetics Implementation Consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing. Clin Pharmacol Ther 2011, 89:387-391. 10.1038/clpt.2010.320, 3098761,3098761, 21270794, Clinical Pharmacogenetics Implementation Consortium.
    • (2011) Clin Pharmacol Ther , vol.89 , pp. 387-391
    • Relling, M.V.1    Gardner, E.E.2    Sandborn, W.J.3    Schmiegelow, K.4    Pui, C.H.5    Yee, S.W.6    Stein, C.M.7    Carrillo, M.8    Evans, W.E.9    Klein, T.E.10
  • 26
    • 70649097090 scopus 로고    scopus 로고
    • Individualization of thiopurine therapy: thiopurine S-methyltransferase and beyond.
    • 10.2217/pgs.09.78, 19663675
    • Karas-Kuzelicki N, Mlinaric-Rascan I. Individualization of thiopurine therapy: thiopurine S-methyltransferase and beyond. Pharmacogenomics 2009, 10:1309-1322. 10.2217/pgs.09.78, 19663675.
    • (2009) Pharmacogenomics , vol.10 , pp. 1309-1322
    • Karas-Kuzelicki, N.1    Mlinaric-Rascan, I.2
  • 28
    • 34548598459 scopus 로고    scopus 로고
    • UGT1A1*28 genotype and irinotecan-induced neutropenia: dose matters.
    • 10.1093/jnci/djm115, 17728214
    • Hoskins JM, Goldberg RM, Qu P, Ibrahim JG, McLeod HL. UGT1A1*28 genotype and irinotecan-induced neutropenia: dose matters. J Natl Cancer Inst 2007, 99:1290-1295. 10.1093/jnci/djm115, 17728214.
    • (2007) J Natl Cancer Inst , vol.99 , pp. 1290-1295
    • Hoskins, J.M.1    Goldberg, R.M.2    Qu, P.3    Ibrahim, J.G.4    McLeod, H.L.5
  • 29
    • 33845893608 scopus 로고    scopus 로고
    • Pharmacogenetics of irinotecan: clinical perspectives on the utility of genotyping.
    • 10.2217/14622416.7.8.1211, 17184208
    • Innocenti F, Ratain MJ. Pharmacogenetics of irinotecan: clinical perspectives on the utility of genotyping. Pharmacogenomics 2006, 7:1211-1221. 10.2217/14622416.7.8.1211, 17184208.
    • (2006) Pharmacogenomics , vol.7 , pp. 1211-1221
    • Innocenti, F.1    Ratain, M.J.2
  • 30
    • 1942453306 scopus 로고    scopus 로고
    • Dihydropyrimidine dehydrogenase and the efficacy and toxicity of 5-fluorouracil.
    • 10.1016/j.ejca.2003.12.004, 15093568
    • van Kuilenburg AB. Dihydropyrimidine dehydrogenase and the efficacy and toxicity of 5-fluorouracil. Eur J Cancer 2004, 40:939-950. 10.1016/j.ejca.2003.12.004, 15093568.
    • (2004) Eur J Cancer , vol.40 , pp. 939-950
    • van Kuilenburg, A.B.1
  • 31
    • 0023187085 scopus 로고
    • Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, and bile.
    • Heggie GD, Sommadossi JP, Cross DS, Huster WJ, Diasio RB. Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, and bile. Cancer Res 1987, 47:2203-2206.
    • (1987) Cancer Res , vol.47 , pp. 2203-2206
    • Heggie, G.D.1    Sommadossi, J.P.2    Cross, D.S.3    Huster, W.J.4    Diasio, R.B.5
  • 32
    • 43749114271 scopus 로고    scopus 로고
    • Role of genetic and nongenetic factors for fluorouracil treatment-related severe toxicity: a prospective clinical trial by the German 5-FU Toxicity Study Group.
    • 10.1200/JCO.2006.10.4182, 18299612, German 5-FU Toxicity Study Group
    • Schwab M, Zanger UM, Marx C, Schaeffeler E, Klein K, Dippon J, Kerb R, Blievernicht J, Fischer J, Hofmann U, Bokemeyer C, Eichelbaum M, . German 5-FU Toxicity Study Group Role of genetic and nongenetic factors for fluorouracil treatment-related severe toxicity: a prospective clinical trial by the German 5-FU Toxicity Study Group. J Clin Oncol 2008, 26:2131-2138. 10.1200/JCO.2006.10.4182, 18299612, German 5-FU Toxicity Study Group.
    • (2008) J Clin Oncol , vol.26 , pp. 2131-2138
    • Schwab, M.1    Zanger, U.M.2    Marx, C.3    Schaeffeler, E.4    Klein, K.5    Dippon, J.6    Kerb, R.7    Blievernicht, J.8    Fischer, J.9    Hofmann, U.10    Bokemeyer, C.11    Eichelbaum, M.12
  • 33
    • 77957778866 scopus 로고    scopus 로고
    • Routine dihydropyrimidine dehydrogenase testing for anticipating 5-fluorouracil-related severe toxicities: hype or hope?.
    • 10.3816/CCC.2010.n.033, 20920994
    • Ciccolini J, Gross E, Dahan L, Lacarelle B, Mercier C. Routine dihydropyrimidine dehydrogenase testing for anticipating 5-fluorouracil-related severe toxicities: hype or hope?. Clin Colorectal Cancer 2010, 9:224-228. 10.3816/CCC.2010.n.033, 20920994.
    • (2010) Clin Colorectal Cancer , vol.9 , pp. 224-228
    • Ciccolini, J.1    Gross, E.2    Dahan, L.3    Lacarelle, B.4    Mercier, C.5
  • 35
    • 40649108301 scopus 로고    scopus 로고
    • Aromatase inhibitors in adjuvant therapy for hormone receptor positive breast cancer: a systematic review.
    • 10.1016/j.ctrv.2007.11.001, 18164821
    • Eisen A, Trudeau M, Shelley W, Messersmith H, Pritchard KI. Aromatase inhibitors in adjuvant therapy for hormone receptor positive breast cancer: a systematic review. Cancer Treat Rev 2008, 34:157-174. 10.1016/j.ctrv.2007.11.001, 18164821.
    • (2008) Cancer Treat Rev , vol.34 , pp. 157-174
    • Eisen, A.1    Trudeau, M.2    Shelley, W.3    Messersmith, H.4    Pritchard, K.I.5
  • 36
    • 79952254324 scopus 로고    scopus 로고
    • Table of Pharmacogenomic Biomarkers in Drug Labels.
    • Table of Pharmacogenomic Biomarkers in Drug Labels. , http://www.fda.gov/drugs/scienceresearch/researchareas/pharmacogenetics/ucm083378.htm
  • 39
    • 6344270174 scopus 로고    scopus 로고
    • Pharmacogenetics of methotrexate.
    • 10.1517/14622416.5.7.819, 15469405
    • Krajinovic M, Moghrabi A. Pharmacogenetics of methotrexate. Pharmacogenomics 2004, 5:819-834. 10.1517/14622416.5.7.819, 15469405.
    • (2004) Pharmacogenomics , vol.5 , pp. 819-834
    • Krajinovic, M.1    Moghrabi, A.2
  • 40
    • 34548137731 scopus 로고    scopus 로고
    • Pharmacogenomics of acute leukemia.
    • 10.2217/14622416.8.7.817, 18240908
    • Ansari M, Krajinovic M. Pharmacogenomics of acute leukemia. Pharmacogenomics 2007, 8:817-834. 10.2217/14622416.8.7.817, 18240908.
    • (2007) Pharmacogenomics , vol.8 , pp. 817-834
    • Ansari, M.1    Krajinovic, M.2
  • 43
    • 4143078229 scopus 로고    scopus 로고
    • Genome-wide discovery of loci influencing chemotherapy cytotoxicity.
    • 10.1073/pnas.0404580101, 511056, 15282376
    • Watters JW, Kraja A, Meucci MA, Province MA, McLeod HL. Genome-wide discovery of loci influencing chemotherapy cytotoxicity. Proc Natl Acad Sci USA 2004, 101:11809-11814. 10.1073/pnas.0404580101, 511056, 15282376.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 11809-11814
    • Watters, J.W.1    Kraja, A.2    Meucci, M.A.3    Province, M.A.4    McLeod, H.L.5
  • 44
    • 65249086733 scopus 로고    scopus 로고
    • Whole-genome approach implicates CD44 in cellular resistance to carboplatin.
    • 10.1186/1479-7364-3-2-128, 2683878, 19164090
    • Shukla SJ, Duan S, Wu X, Badner JA, Kasza K, Dolan ME. Whole-genome approach implicates CD44 in cellular resistance to carboplatin. Hum Genomics 2009, 3:128-142. 10.1186/1479-7364-3-2-128, 2683878, 19164090.
    • (2009) Hum Genomics , vol.3 , pp. 128-142
    • Shukla, S.J.1    Duan, S.2    Wu, X.3    Badner, J.A.4    Kasza, K.5    Dolan, M.E.6
  • 45
    • 34347208347 scopus 로고    scopus 로고
    • Mapping genes that contribute to daunorubicin-induced cytotoxicity.
    • 10.1158/0008-5472.CAN-06-4431, 2735868, 17545624
    • Duan S, Bleibel WK, Huang RS, Shukla SJ, Wu X, Badner JA, Dolan ME. Mapping genes that contribute to daunorubicin-induced cytotoxicity. Cancer Res 2007, 67:5425-5433. 10.1158/0008-5472.CAN-06-4431, 2735868, 17545624.
    • (2007) Cancer Res , vol.67 , pp. 5425-5433
    • Duan, S.1    Bleibel, W.K.2    Huang, R.S.3    Shukla, S.J.4    Wu, X.5    Badner, J.A.6    Dolan, M.E.7
  • 46
    • 79959503826 scopus 로고    scopus 로고
    • The International HapMap Project.
    • 10.1038/nature02168, 14685227, International HapMap Consortium
    • International HapMap Consortium The International HapMap Project. Nature 2003, 426:789-796. 10.1038/nature02168, 14685227, International HapMap Consortium.
    • (2003) Nature , vol.426 , pp. 789-796
  • 47
    • 84975742565 scopus 로고    scopus 로고
    • A map of human genome variation from population-scale sequencing.
    • 10.1038/nature09534, 3042601, 20981092, 1000 Genomes Project Consortium
    • 1000 Genomes Project Consortium A map of human genome variation from population-scale sequencing. Nature 2010, 467:1061-1073. 10.1038/nature09534, 3042601, 20981092, 1000 Genomes Project Consortium.
    • (2010) Nature , vol.467 , pp. 1061-1073
  • 48
    • 79959524146 scopus 로고    scopus 로고
    • A haplotype map of the human genome.
    • 10.1038/nature04226, 1880871, 16255080, International HapMap Consortium
    • International HapMap Consortium A haplotype map of the human genome. Nature 2005, 437:1299-1320. 10.1038/nature04226, 1880871, 16255080, International HapMap Consortium.
    • (2005) Nature , vol.437 , pp. 1299-1320
  • 51
    • 79960688508 scopus 로고    scopus 로고
    • DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines.
    • 10.1186/gb-2011-12-1-r10, 3091299, 21251332
    • Bell JT, Pai AA, Pickrell JK, Gaffney DJ, Pique-Regi R, Degner JF, Gilad Y, Pritchard JK. DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines. Genome Biol 2011, 12:R10. 10.1186/gb-2011-12-1-r10, 3091299, 21251332.
    • (2011) Genome Biol , vol.12
    • Bell, J.T.1    Pai, A.A.2    Pickrell, J.K.3    Gaffney, D.J.4    Pique-Regi, R.5    Degner, J.F.6    Gilad, Y.7    Pritchard, J.K.8
  • 52
    • 84856791176 scopus 로고    scopus 로고
    • Population-specificity of human DNA methylation.
    • 10.1186/gb-2012-13-2-r8, 3334571, 22322129
    • Fraser HB, Lam LL, Neumann SM, Kobor MS. Population-specificity of human DNA methylation. Genome Biol 2012, 13:R8. 10.1186/gb-2012-13-2-r8, 3334571, 22322129.
    • (2012) Genome Biol , vol.13
    • Fraser, H.B.1    Lam, L.L.2    Neumann, S.M.3    Kobor, M.S.4
  • 54
    • 78149459713 scopus 로고    scopus 로고
    • Exprtarget: an integrative approach to predicting human microRNA targets.
    • 10.1371/journal.pone.0013534, 2958831, 20975837
    • Gamazon ER, Im HK, Duan S, Lussier YA, Cox NJ, Dolan ME, Zhang W. Exprtarget: an integrative approach to predicting human microRNA targets. PLoS One 2010, 5:e13534. 10.1371/journal.pone.0013534, 2958831, 20975837.
    • (2010) PLoS One , vol.5
    • Gamazon, E.R.1    Im, H.K.2    Duan, S.3    Lussier, Y.A.4    Cox, N.J.5    Dolan, M.E.6    Zhang, W.7
  • 55
    • 79954499505 scopus 로고    scopus 로고
    • Comprehensive DNA methylation analysis of human peripheral blood leukocytes and lymphoblastoid cell lines.
    • 10.4161/epi.6.4.14876, 3100768, 21304276
    • Sugawara H, Iwamoto K, Bundo M, Ueda J, Ishigooka J, Kato T. Comprehensive DNA methylation analysis of human peripheral blood leukocytes and lymphoblastoid cell lines. Epigenetics 2011, 6:508-515. 10.4161/epi.6.4.14876, 3100768, 21304276.
    • (2011) Epigenetics , vol.6 , pp. 508-515
    • Sugawara, H.1    Iwamoto, K.2    Bundo, M.3    Ueda, J.4    Ishigooka, J.5    Kato, T.6
  • 56
    • 84865213776 scopus 로고    scopus 로고
    • Methylome-wide comparison of human genomic DNA extracted from whole blood and from EBV-transformed lymphocyte cell lines.
    • 10.1038/ejhg.2012.33, 22378283
    • Åberg K, Khachane AN, Rudolf G, Nerella S, Fugman DA, Tischfield JA, van den Oord EJ. Methylome-wide comparison of human genomic DNA extracted from whole blood and from EBV-transformed lymphocyte cell lines. Eur J Hum Genet 2012, 20:953-955. 10.1038/ejhg.2012.33, 22378283.
    • (2012) Eur J Hum Genet , vol.20 , pp. 953-955
    • Åberg, K.1    Khachane, A.N.2    Rudolf, G.3    Nerella, S.4    Fugman, D.A.5    Tischfield, J.A.6    van den Oord, E.J.7
  • 57
    • 84861455911 scopus 로고    scopus 로고
    • Discovery of regulatory elements in human ATP-binding cassette transporters through expression quantitative trait mapping.
    • 10.1038/tpj.2011.8, 21383772
    • Matsson P, Yee SW, Markova S, Morrissey K, Jenkins G, Xuan J, Jorgenson E, Kroetz DL, Giacomini KM. Discovery of regulatory elements in human ATP-binding cassette transporters through expression quantitative trait mapping. Pharmacogenomics J 2012, 12:214-226. 10.1038/tpj.2011.8, 21383772.
    • (2012) Pharmacogenomics J , vol.12 , pp. 214-226
    • Matsson, P.1    Yee, S.W.2    Markova, S.3    Morrissey, K.4    Jenkins, G.5    Xuan, J.6    Jorgenson, E.7    Kroetz, D.L.8    Giacomini, K.M.9
  • 59
    • 84864661973 scopus 로고    scopus 로고
    • Identification of novel germline polymorphisms governing capecitabine sensitivity.
    • 10.1002/cncr.26737, 22864933
    • O'Donnell P, Stark A. Identification of novel germline polymorphisms governing capecitabine sensitivity. Cancer 2012, 118:4063-4073. 10.1002/cncr.26737, 22864933.
    • (2012) Cancer , vol.118 , pp. 4063-4073
    • O'Donnell, P.1    Stark, A.2
  • 61
    • 77952697081 scopus 로고    scopus 로고
    • Chemotherapeutic drug susceptibility associated SNPs are enriched in expression quantitative trait loci.
    • 10.1073/pnas.1001827107, 2889115, 20442332
    • Gamazon ER, Huang RS, Cox NJ, Dolan ME. Chemotherapeutic drug susceptibility associated SNPs are enriched in expression quantitative trait loci. Proc Natl Acad Sci USA 2010, 107:9287-9292. 10.1073/pnas.1001827107, 2889115, 20442332.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 9287-9292
    • Gamazon, E.R.1    Huang, R.S.2    Cox, N.J.3    Dolan, M.E.4
  • 63
    • 63849194095 scopus 로고    scopus 로고
    • Population-specific genetic variants important in susceptibility to cytarabine arabinoside cytotoxicity.
    • 10.1182/blood-2008-05-154302, 2652364, 19109566
    • Hartford CM, Duan S, Delaney SM, Mi S, Kistner EO, Lamba JK, Huang RS, Dolan ME. Population-specific genetic variants important in susceptibility to cytarabine arabinoside cytotoxicity. Blood 2009, 113:2145-2153. 10.1182/blood-2008-05-154302, 2652364, 19109566.
    • (2009) Blood , vol.113 , pp. 2145-2153
    • Hartford, C.M.1    Duan, S.2    Delaney, S.M.3    Mi, S.4    Kistner, E.O.5    Lamba, J.K.6    Huang, R.S.7    Dolan, M.E.8
  • 64
    • 84859779521 scopus 로고    scopus 로고
    • Novel therapeutic strategies for AML in 2012.
    • Tallman MS. Novel therapeutic strategies for AML in 2012. Hematology 2012, 17(Suppl 1):S43-46.
    • (2012) Hematology , vol.17 , Issue.SUPPL. 1
    • Tallman, M.S.1
  • 66
    • 80051801445 scopus 로고    scopus 로고
    • Impact of genetic variation in FKBP5 on clinical response in pediatric acute myeloid leukemia patients: a pilot study.
    • 10.1038/leu.2011.74, 3238383, 21483441
    • Mitra AK, Crews K, Pounds S, Cao X, Downing JR, Raimondi S, Campana D, Ribeiro RC, Rubnitz JE, Lamba JK. Impact of genetic variation in FKBP5 on clinical response in pediatric acute myeloid leukemia patients: a pilot study. Leukemia 2011, 25:1354-1356. 10.1038/leu.2011.74, 3238383, 21483441.
    • (2011) Leukemia , vol.25 , pp. 1354-1356
    • Mitra, A.K.1    Crews, K.2    Pounds, S.3    Cao, X.4    Downing, J.R.5    Raimondi, S.6    Campana, D.7    Ribeiro, R.C.8    Rubnitz, J.E.9    Lamba, J.K.10
  • 69
    • 80052442469 scopus 로고    scopus 로고
    • Genetic variation predicting cisplatin cytotoxicity associated with overall survival in lung cancer patients receiving platinum-based chemotherapy.
    • 10.1158/1078-0432.CCR-11-1133, 3167019, 21775533
    • Tan XL, Moyer AM, Fridley BL, Schaid DJ, Niu N, Batzler AJ, Jenkins GD, Abo RP, Li L, Cunningham JM, Sun Z, Yang P, Wang L. Genetic variation predicting cisplatin cytotoxicity associated with overall survival in lung cancer patients receiving platinum-based chemotherapy. Clin Cancer Res 2011, 17:5801-5811. 10.1158/1078-0432.CCR-11-1133, 3167019, 21775533.
    • (2011) Clin Cancer Res , vol.17 , pp. 5801-5811
    • Tan, X.L.1    Moyer, A.M.2    Fridley, B.L.3    Schaid, D.J.4    Niu, N.5    Batzler, A.J.6    Jenkins, G.D.7    Abo, R.P.8    Li, L.9    Cunningham, J.M.10    Sun, Z.11    Yang, P.12    Wang, L.13
  • 70
    • 35348949634 scopus 로고    scopus 로고
    • Paclitaxel: a review of adverse toxicities and novel delivery strategies.
    • 10.1517/14740338.6.5.609, 17877447
    • Marupudi NI, Han JE, Li KW, Renard VM, Tyler BM, Brem H. Paclitaxel: a review of adverse toxicities and novel delivery strategies. Expert Opin Drug Saf 2007, 6:609-621. 10.1517/14740338.6.5.609, 17877447.
    • (2007) Expert Opin Drug Saf , vol.6 , pp. 609-621
    • Marupudi, N.I.1    Han, J.E.2    Li, K.W.3    Renard, V.M.4    Tyler, B.M.5    Brem, H.6
  • 71
    • 80052031639 scopus 로고    scopus 로고
    • Chemotherapy-induced peripheral neuropathy: prevention and treatment.
    • 10.1038/clpt.2011.115, 21814197
    • Pachman DR, Barton DL, Watson JC, Loprinzi CL. Chemotherapy-induced peripheral neuropathy: prevention and treatment. Clin Pharmacol Ther 2011, 90:377-387. 10.1038/clpt.2011.115, 21814197.
    • (2011) Clin Pharmacol Ther , vol.90 , pp. 377-387
    • Pachman, D.R.1    Barton, D.L.2    Watson, J.C.3    Loprinzi, C.L.4
  • 72
    • 84866617047 scopus 로고    scopus 로고
    • Clinical translation of cell-based pharmacogenomic discovery.
    • 10.1038/clpt.2012.115, 22910437
    • Cox NJ, Gamazon ER, Wheeler HE, Dolan ME. Clinical translation of cell-based pharmacogenomic discovery. Clin Pharmacol Ther 2012, 92:425-427. 10.1038/clpt.2012.115, 22910437.
    • (2012) Clin Pharmacol Ther , vol.92 , pp. 425-427
    • Cox, N.J.1    Gamazon, E.R.2    Wheeler, H.E.3    Dolan, M.E.4
  • 74
    • 77953543620 scopus 로고    scopus 로고
    • Clinical implementation of pharmacogenomics: overcoming genetic exceptionalism.
    • 10.1016/S1470-2045(10)70097-8, 20413348
    • Relling MV, Altman RB, Goetz MP, Evans WE. Clinical implementation of pharmacogenomics: overcoming genetic exceptionalism. Lancet Oncol 2010, 11:507-509. 10.1016/S1470-2045(10)70097-8, 20413348.
    • (2010) Lancet Oncol , vol.11 , pp. 507-509
    • Relling, M.V.1    Altman, R.B.2    Goetz, M.P.3    Evans, W.E.4
  • 75
    • 79955685734 scopus 로고    scopus 로고
    • Clinically relevant genetic variations in drug metabolizing enzymes.
    • 10.2174/138920011795495321, 3110519, 21453273
    • Pinto N, Dolan ME. Clinically relevant genetic variations in drug metabolizing enzymes. Curr Drug Metab 2011, 12:487-497. 10.2174/138920011795495321, 3110519, 21453273.
    • (2011) Curr Drug Metab , vol.12 , pp. 487-497
    • Pinto, N.1    Dolan, M.E.2
  • 76
    • 84866595897 scopus 로고    scopus 로고
    • The 1200 patients project: creating a new medical model system for clinical implementation of pharmacogenomics.
    • 10.1038/clpt.2012.117, 22929923
    • O'Donnell PH, Bush A, Spitz J, Danahey K, Saner D, Das S, Cox NJ, Ratain MJ. The 1200 patients project: creating a new medical model system for clinical implementation of pharmacogenomics. Clin Pharmacol Ther 2012, 92:446-449. 10.1038/clpt.2012.117, 22929923.
    • (2012) Clin Pharmacol Ther , vol.92 , pp. 446-449
    • O'Donnell, P.H.1    Bush, A.2    Spitz, J.3    Danahey, K.4    Saner, D.5    Das, S.6    Cox, N.J.7    Ratain, M.J.8
  • 77
    • 79955008129 scopus 로고    scopus 로고
    • Databases in the area of pharmacogenetics.
    • 10.1002/humu.21454, 3352027, 21309040
    • Sim SC, Altman RB, Ingelman-Sundberg M. Databases in the area of pharmacogenetics. Hum Mutat 2011, 32:526-531. 10.1002/humu.21454, 3352027, 21309040.
    • (2011) Hum Mutat , vol.32 , pp. 526-531
    • Sim, S.C.1    Altman, R.B.2    Ingelman-Sundberg, M.3
  • 78
    • 27744460659 scopus 로고    scopus 로고
    • PharmGKB: the pharmacogenetics and pharmacogenomics knowledge base.
    • Thorn CF, Klein TE, Altman RB. PharmGKB: the pharmacogenetics and pharmacogenomics knowledge base. Methods Mol Biol 2005, 311:179-191.
    • (2005) Methods Mol Biol , vol.311 , pp. 179-191
    • Thorn, C.F.1    Klein, T.E.2    Altman, R.B.3
  • 79
    • 79951809825 scopus 로고    scopus 로고
    • CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network.
    • 10.1038/clpt.2010.279, 3098762,3098762, 21270786
    • Relling MV, Klein TE. CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network. Clin Pharmacol Ther 2011, 89:464-467. 10.1038/clpt.2010.279, 3098762,3098762, 21270786.
    • (2011) Clin Pharmacol Ther , vol.89 , pp. 464-467
    • Relling, M.V.1    Klein, T.E.2
  • 80
  • 85
    • 33748445361 scopus 로고    scopus 로고
    • Symptom improvement in lung cancer patients treated with erlotinib: quality of life analysis of the National Cancer Institute of Canada Clinical Trials Group Study BR.21.
    • 10.1200/JCO.2006.05.8073, 16921034, National Cancer Institute of Canada Clinical Trials Group Study BR.21
    • Bezjak A, Tu D, Seymour L, Clark G, Trajkovic A, Zukin M, Ayoub J, Lago S, de Albuquerque Ribeiro R, Gerogianni A, Cyjon A, Noble J, Laberge F, Chan RT, Fenton D, von Pawel J, Reck M, Shepherd FA, . National Cancer Institute of Canada Clinical Trials Group Study BR.21 Symptom improvement in lung cancer patients treated with erlotinib: quality of life analysis of the National Cancer Institute of Canada Clinical Trials Group Study BR.21. J Clin Oncol 2006, 24:3831-3837. 10.1200/JCO.2006.05.8073, 16921034, National Cancer Institute of Canada Clinical Trials Group Study BR.21.
    • (2006) J Clin Oncol , vol.24 , pp. 3831-3837
    • Bezjak, A.1    Tu, D.2    Seymour, L.3    Clark, G.4    Trajkovic, A.5    Zukin, M.6    Ayoub, J.7    Lago, S.8    de Albuquerque Ribeiro, R.9    Gerogianni, A.10    Cyjon, A.11    Noble, J.12    Laberge, F.13    Chan, R.T.14    Fenton, D.15    von Pawel, J.16    Reck, M.17    Shepherd, F.A.18
  • 89
    • 0038102704 scopus 로고    scopus 로고
    • Rasburicase for the treatment and prevention of hyperuricemia.
    • 10.1345/aph.1C336, 12841818
    • Yim BT, Sims-McCallum RP, Chong PH. Rasburicase for the treatment and prevention of hyperuricemia. Ann Pharmacother 2003, 37:1047-1054. 10.1345/aph.1C336, 12841818.
    • (2003) Ann Pharmacother , vol.37 , pp. 1047-1054
    • Yim, B.T.1    Sims-McCallum, R.P.2    Chong, P.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.