Pharmacogenomic characterization of US FDA-approved cytotoxic drugs

Pharmacogenomics

Volumn 12, Issue 10, 2011, Pages 1407-1415

  Peters, Eric J ^a,b,c   Motsinger Reif, Alison ^a,d   Havener, Tammy M ^a,b   Everitt, Lorraine ^a,b   Hardison, Nicholas E ^d   Watson, Venita G ^a,b   Wagner, Michael ^a,b   Richards, Kristy L ^a,b,e,f   Province, Mike A ^g   McLeod, Howard L ^a,b,e,f  

^a University of North Carolina   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c ILLUMINA INC   (United States)

^d NORTH CAROLINA STATE UNIVERSITY   (United States)

^e UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF NORTH CAROLINA   (United States)

^g WASHINGTON UNIVERSITY   (United States)

Author keywords

cancer; cell line; chemotherapy; cytotoxicity; pharmacogenetics; pharmacogenomic; QTL

Indexed keywords

ARSENIC TRIOXIDE; AZACITIDINE; BLEOMYCIN; BUSULFAN; CARBOPLATIN; CLADRIBINE; CYTARABINE; CYTOTOXIC AGENT; DAUNORUBICIN; DOCETAXEL; DOXORUBICIN; EPIRUBICIN; ETOPOSIDE; FLOXURIDINE; FLUDARABINE; FLUOROURACIL; GEMCITABINE; HYDROXYUREA; IDARUBICIN; MITOMYCIN; MITOXANTRONE; NAVELBINE; OXALIPLATIN; PACLITAXEL; RAPAMYCIN; TEMOZOLOMIDE; TENIPOSIDE; VINBLASTINE; VINCRISTINE;

ADVERSE DRUG REACTION; ARTICLE; CANCER CHEMOTHERAPY; CONTROLLED STUDY; DRUG APPROVAL; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG RESPONSE; EXTENDED FAMILY; FOOD AND DRUG ADMINISTRATION; GENETIC VARIABILITY; HERITABILITY; HUMAN; HUMAN CELL; LYMPHOBLASTOID CELL LINE; PHARMACOGENOMICS; QUANTITATIVE TRAIT LOCUS;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG APPROVAL; GENETIC LINKAGE; HUMANS; PHARMACOGENETICS; QUANTITATIVE TRAIT LOCI; UNITED STATES; UNITED STATES FOOD AND DRUG ADMINISTRATION;

EID: 80054935563     PISSN: 14622416     EISSN: 17448042     Source Type: Journal    
DOI: 10.2217/pgs.11.92     Document Type: Article

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