Antimicrobial and cell-penetrating properties of penetratin analogs: Effect of sequence and secondary structure

Biochimica et Biophysica Acta - Biomembranes

Volumn 1828, Issue 2, 2013, Pages 223-232

  Bahnsen, Jesper Søborg ^a   Franzyk, Henrik ^a   Sandberg Schaal, Anne ^b   Nielsen, Hanne Mørck ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b HVIDOVRE HOSPITAL   (Denmark)

Author keywords

Antimicrobial peptide; Cell penetrating peptide; Intracellular delivery; Membrane activity; Protein transduction domain; Secondary structure

Indexed keywords

ARGININE; CELL PENETRATING PEPTIDE; GUANIDINE; LEUCINE; LIPOSOME; METHIONINE; OCTAARGININE; PENETRATIN; PENETRATIN DERIVATIVE; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO ACID COMPOSITION; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL CELL; CELL MEMBRANE TRANSPORT; CELL TRANSPORT; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG CYTOTOXICITY; ESCHERICHIA COLI; HELA CELL; HEMOLYSIS; HUMAN; HUMAN CELL; MEMBRANE BINDING; MEMBRANE DAMAGE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; STAPHYLOCOCCUS AUREUS;

AMINO ACID SEQUENCE; ANTI-INFECTIVE AGENTS; ARGININE; CARRIER PROTEINS; CELL SURVIVAL; CELL-PENETRATING PEPTIDES; CHOLESTEROL; CIRCULAR DICHROISM; DRUG DELIVERY SYSTEMS; ERYTHROCYTES; FLOW CYTOMETRY; HELA CELLS; HUMANS; LIPOSOMES; MICROSCOPY, CONFOCAL; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; PEPTIDES; PROTEIN STRUCTURE, SECONDARY;

BACTERIA (MICROORGANISMS); EUKARYOTA; MAMMALIA; NEGIBACTERIA; POSIBACTERIA;

EID: 84869861771     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2012.10.010     Document Type: Article

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