Investigation of penetratin peptides. Part 1. The environment dependent conformational properties of penetratin and two of its derivatives

Journal of Peptide Science

Volumn 8, Issue 4, 2002, Pages 151-171

  Czajlik, András ^a   Meskó, Eszter ^b   Penke, Botond ^b   Perczel, András ^a  

^a EÖTVÖS LORÁND UNIVERSITY   (Hungary)

^b UNIVERSITY OF SZEGED   (Hungary)

Author keywords

CD; Conformational ensemble; Helical structure; NMR; Penetratin; TFEd2 water mixtures

Indexed keywords

HOMEODOMAIN PROTEIN; OLIGONUCLEOTIDE; OLIGOPEPTIDE; PENETRATIN; PROTEIN DERIVATIVE; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO ACID COMPOSITION; AMINO TERMINAL SEQUENCE; ARTICLE; CELL MEMBRANE TRANSPORT; CELL NUCLEUS; CELL POLARITY; CHEMICAL INTERACTION; CIRCULAR DICHROISM; CONTROLLED STUDY; DNA BINDING; HYDROGEN BOND; HYDROPHOBICITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; CARRIER PROTEINS; CIRCULAR DICHROISM; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SOLUTIONS;

EID: 0036237709     PISSN: 10752617     EISSN: None     Source Type: Journal    
DOI: 10.1002/psc.380     Document Type: Article

References (29)

1. Homeo boxes in the study of development
2. The structure of the Antennapedia homeodomain determined by NMR spectroscopy in solution: Comparison with prokaryotic repressors
3. NMR structure determination reveals that the homeodomain is connected through a flexible linker to the main body in the Drosophila Antennapedia protein
4. 13C-labeled Antennapedia homeodomain and structure determination of the DNA-bound homeodomain
5. Neurotrophic activity of Antennapedia homeodomain depends on its specific DNA-binding properties
6. The third helix of the Antennapedia homeodomain translocates through biological membranes
7. Cell internalization of the third helix of the Antennapedia is receptor-independent
8. The Antennapedia peptide penetratin translocates across lipid bilayers - The first direct observation
9. Intraneuronal delivery of protein kinase C pseudosubstrate leads to growth cone collapse
10. Down regulation of SOD1 leads to cell death by the NO-peroxy-nitrite pathway
11. Trojan peptides: The penetratin system for intracellular delivery
12. Conformational and associative behaviours of the third helix of antennapedia homeodomain in membrane-mimetic environments
13. Importance of environment in determining secondary structure in proteins
14. Determination of three-dimensional structures of proteins from interproton distance data by dynamical simulated annealing from a random array of atoms
15. MOLMOL: A program for display and analysis of macromolecular structures
16. Convex constraint analysis: A natural deconvolution of circular dichroism curves of proteins
17. Analysis of the circular dichroism spectra of proteins using the convex constraint algorithm: A practical guide
18. Folding of immunogenic peptide fragments of proteins in water solution II. The nascent helix
19. The chemical shift index: A fast and simple method for the assignment of protein secondary structure through NMR spectroscopy
20. 1 H, 13 C and 15N random coil NMR chemical shifts of the common amino acids. I. Investigations of the nearest-neighbour effects
21. Studies of synthetic helical peptides using circular dichroism and nuclear magnetic resonance
22. Local structures in unfolded lysozyme and correlation with native conformation: Helix-forming or breaking propensity of peptide segments
23. The homologous angiogenin and ribonuclease N-terminal fragments fold into very similar helices when isolated
24. Folding of peptide fragments comprising the complete sequence of proteins. Models for initiation of protein folding. I. Myohermerythrin