메뉴 건너뛰기




Volumn 120, Issue 22, 2012, Pages 4334-4342

T-cell receptor gene transfer exclusively to human CD8+ cells enhances tumor cell killing

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; GRANZYME B; LENTIVIRUS VECTOR; PERFORIN; T LYMPHOCYTE RECEPTOR;

EID: 84869758434     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-02-412973     Document Type: Article
Times cited : (48)

References (49)
  • 1
    • 79954692758 scopus 로고    scopus 로고
    • Ex vivo gene transfer and correction for cell-based therapies
    • Naldini L. Ex vivo gene transfer and correction for cell-based therapies. Nat Rev Genet. 2011;12(5):301-315.
    • (2011) Nat Rev Genet , vol.12 , Issue.5 , pp. 301-315
    • Naldini, L.1
  • 2
    • 68849130990 scopus 로고    scopus 로고
    • Lentiviral vector design for optimal T cell receptor gene expression in the transduction of peripheral blood lymphocytes and tumor-infiltrating lymphocytes
    • Jones S, Peng PD, Yang S, et al. Lentiviral vector design for optimal T cell receptor gene expression in the transduction of peripheral blood lymphocytes and tumor-infiltrating lymphocytes. Hum Gene Ther. 2009;20(6):630-640.
    • (2009) Hum Gene Ther , vol.20 , Issue.6 , pp. 630-640
    • Jones, S.1    Peng, P.D.2    Yang, S.3
  • 3
    • 77951142159 scopus 로고    scopus 로고
    • Enhanced T cell receptor gene therapy for cancer
    • Kieback E, Uckert W. Enhanced T cell receptor gene therapy for cancer. Expert Opin Biol Ther. 2010;10(5):749-762.
    • (2010) Expert Opin Biol Ther , vol.10 , Issue.5 , pp. 749-762
    • Kieback, E.1    Uckert, W.2
  • 4
    • 67349217106 scopus 로고    scopus 로고
    • Cell typespecific targeting with surface-engineered lentiviral vectors co-displaying OKT3 antibody and fusogenic molecule
    • Yang H, Joo KI, Ziegler L, Wang P. Cell typespecific targeting with surface-engineered lentiviral vectors co-displaying OKT3 antibody and fusogenic molecule. Pharm Res. 2009;26(6):1432-1445.
    • (2009) Pharm Res , vol.26 , Issue.6 , pp. 1432-1445
    • Yang, H.1    Joo, K.I.2    Ziegler, L.3    Wang, P.4
  • 5
    • 80051873375 scopus 로고    scopus 로고
    • CD8(+) T cells: Foot soldiers of the immune system
    • Zhang N, Bevan MJ. CD8(+) T cells: foot soldiers of the immune system. Immunity. 2011;35(2):161-168.
    • (2011) Immunity , vol.35 , Issue.2 , pp. 161-168
    • Zhang, N.1    Bevan, M.J.2
  • 6
    • 80051720194 scopus 로고    scopus 로고
    • Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia
    • Porter DL, Levine BL, Kalos M, Bagg A, June CH. Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia. N Engl J Med. 2011;365(8):725-733.
    • (2011) N Engl J Med , vol.365 , Issue.8 , pp. 725-733
    • Porter, D.L.1    Levine, B.L.2    Kalos, M.3    Bagg, A.4    June, C.H.5
  • 7
    • 50549096284 scopus 로고    scopus 로고
    • Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20-specific T cells
    • Till BG, Jensen MC, Wang J, et al. Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20-specific T cells. Blood. 2008;112(6):2261-2271.
    • (2008) Blood , vol.112 , Issue.6 , pp. 2261-2271
    • Till, B.G.1    Jensen, M.C.2    Wang, J.3
  • 10
    • 78049345098 scopus 로고    scopus 로고
    • Specific gene transfer to neurons, endothelial cells and hematopoietic progenitors with lentiviral vectors
    • Anliker B, Abel T, Kneissl S, et al. Specific gene transfer to neurons, endothelial cells and hematopoietic progenitors with lentiviral vectors. Nat Methods. 2010;7(11):929-935.
    • (2010) Nat Methods , vol.7 , Issue.11 , pp. 929-935
    • Anliker, B.1    Abel, T.2    Kneissl, S.3
  • 11
    • 79953331925 scopus 로고    scopus 로고
    • DARPins: An efficient targeting domain for lentiviral vectors
    • Münch RC, Muhlebach MD, Schaser T, et al. DARPins: an efficient targeting domain for lentiviral vectors. Mol Ther. 2011;19(4):686-693.
    • (2011) Mol Ther , vol.19 , Issue.4 , pp. 686-693
    • Münch, R.C.1    Muhlebach, M.D.2    Schaser, T.3
  • 12
    • 0034635335 scopus 로고    scopus 로고
    • Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides
    • Knappik A, Ge L, Honegger A, et al. Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides. J Mol Biol. 2000;296(1):57-86.
    • (2000) J Mol Biol , vol.296 , Issue.1 , pp. 57-86
    • Knappik, A.1    Ge, L.2    Honegger, A.3
  • 14
    • 22144496809 scopus 로고    scopus 로고
    • Redirecting human T lymphocytes toward renal cell carcinoma specificity by retroviral transfer of T cell receptor genes
    • DOI 10.1089/hum.2005.16.799
    • Engels B, Noessner E, Frankenberger B, Blankenstein T, Schendel DJ, Uckert W. Redirecting human T lymphocytes toward renal cell carcinoma specificity by retroviral transfer of T cell receptor genes. Hum Gene Ther. 2005;16(7):799-810. (Pubitemid 40982329)
    • (2005) Human Gene Therapy , vol.16 , Issue.7 , pp. 799-810
    • Engels, B.1    Noessner, E.2    Frankenberger, B.3    Blankenstein, T.4    Schendel, D.J.5    Uckert, W.6
  • 16
    • 0034322479 scopus 로고    scopus 로고
    • Context dependence of different modules for posttranscriptional enhancement of gene expression from retroviral vectors
    • Schambach A, Wodrich H, Hildinger M, Bohne J, Krausslich HG, Baum C. Context dependence of different modules for posttranscriptional enhancement of gene expression from retroviral vectors. Mol Ther. 2000;2(5):435-445.
    • (2000) Mol Ther , vol.2 , Issue.5 , pp. 435-445
    • Schambach, A.1    Wodrich, H.2    Hildinger, M.3    Bohne, J.4    Krausslich, H.G.5    Baum, C.6
  • 17
    • 30344464717 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase in hematopoietic cells
    • DOI 10.1016/j.ymthe.2005.08.012, PII S1525001605015662
    • Schambach A, Bohne J, Chandra S, et al. Equal potency of gammaretroviral and lentiviral SIN vectors for expression of O6-methylguanine-DNA methyltransferase in hematopoietic cells. Mol Ther. 2006;13(2):391-400. (Pubitemid 43056905)
    • (2006) Molecular Therapy , vol.13 , Issue.2 , pp. 391-400
    • Schambach, A.1    Bohne, J.2    Chandra, S.3    Will, E.4    Margison, G.P.5    Williams, D.A.6    Baum, C.7
  • 18
    • 70349248241 scopus 로고    scopus 로고
    • Dendritic cells pulsed with RNA encoding allogeneic MHC and antigen induce T cells with superior antitumor activity and higher TCR functional avidity
    • Wilde S, Sommermeyer D, Frankenberger B, et al. Dendritic cells pulsed with RNA encoding allogeneic MHC and antigen induce T cells with superior antitumor activity and higher TCR functional avidity. Blood. 2009;114(10):2131-2139.
    • (2009) Blood , vol.114 , Issue.10 , pp. 2131-2139
    • Wilde, S.1    Sommermeyer, D.2    Frankenberger, B.3
  • 19
    • 48349147731 scopus 로고    scopus 로고
    • Targeted cell entry of lentiviral vectors
    • Funke S, Maisner A, Muhlebach MD, et al. Targeted cell entry of lentiviral vectors. Mol Ther. 2008;16(8):1427-1436.
    • (2008) Mol Ther , vol.16 , Issue.8 , pp. 1427-1436
    • Funke, S.1    Maisner, A.2    Muhlebach, M.D.3
  • 20
    • 77949325014 scopus 로고    scopus 로고
    • A single TCR alpha-chain with dominant peptide recognition in the allorestricted HER2/neu-specific T cell repertoire
    • Liang X, Weigand LU, Schuster IG, et al. A single TCR alpha-chain with dominant peptide recognition in the allorestricted HER2/neu-specific T cell repertoire. J Immunol. 2010;184(3):1617-1629.
    • (2010) J Immunol , vol.184 , Issue.3 , pp. 1617-1629
    • Liang, X.1    Weigand, L.U.2    Schuster, I.G.3
  • 21
    • 0029061997 scopus 로고
    • Quantitative correlation between HLA class I allele expression and recognition of melanoma cells by antigen-specific cytotoxic T lymphocytes
    • Rivoltini L, Barracchini KC, Viggiano V, et al. Quantitative correlation between HLA class I allele expression and recognition of melanoma cells by antigen-specific cytotoxic T lymphocytes. Cancer Res. 1995;55(14):3149-3157.
    • (1995) Cancer Res , vol.55 , Issue.14 , pp. 3149-3157
    • Rivoltini, L.1    Barracchini, K.C.2    Viggiano, V.3
  • 22
    • 79954628140 scopus 로고    scopus 로고
    • Resting lymphocyte transduction with measles virus glycoprotein pseudotyped lentiviral vectors relies on CD46 and SLAM
    • Zhou Q, Schneider IC, Gallet M, Kneissl S, Buchholz CJ. Resting lymphocyte transduction with measles virus glycoprotein pseudotyped lentiviral vectors relies on CD46 and SLAM. Virology. 2011;413(2):149-152.
    • (2011) Virology , vol.413 , Issue.2 , pp. 149-152
    • Zhou, Q.1    Schneider, I.C.2    Gallet, M.3    Kneissl, S.4    Buchholz, C.J.5
  • 23
    • 37349039692 scopus 로고    scopus 로고
    • Expression of a CD20-specific chimeric antigen receptor enhances cytotoxic activity of NK cells and overcomes NK-resistance of lymphoma and leukemia cells
    • DOI 10.1007/s00262-007-0383-3
    • Müller T, Uherek C, Maki G, et al. Expression of a CD20-specific chimeric antigen receptor enhances cytotoxic activity of NK cells and overcomes NK-resistance of lymphoma and leukemia cells. Cancer Immunol Immunother. 2008;57(3):411-423. (Pubitemid 350295385)
    • (2008) Cancer Immunology, Immunotherapy , vol.57 , Issue.3 , pp. 411-423
    • Muller, T.1    Uherek, C.2    Maki, G.3    Chow, K.U.4    Schimpf, A.5    Klingemann, H.-G.6    Tonn, T.7    Wels, W.S.8
  • 24
    • 0018701862 scopus 로고
    • Monoclonal antibodies defining distinctive human T cell surface antigens
    • Kung P, Goldstein G, Reinherz EL, Schlossman SF. Monoclonal antibodies defining distinctive human T cell surface antigens. Science. 1979;206(4416):347-349. (Pubitemid 10244191)
    • (1979) Science , vol.206 , Issue.4416 , pp. 347-349
    • Kung, P.C.1    Goldstein, G.2    Reinherz, E.L.3    Schlossman, S.F.4
  • 25
    • 67349147418 scopus 로고    scopus 로고
    • Pseudotyping lentiviral vectors with the wild-type measles virus glycoproteins improves titer and selectivity
    • Funke S, Schneider IC, Glaser S, et al. Pseudotyping lentiviral vectors with the wild-type measles virus glycoproteins improves titer and selectivity. Gene Ther. 2009;16(5):700-705.
    • (2009) Gene Ther , vol.16 , Issue.5 , pp. 700-705
    • Funke, S.1    Schneider, I.C.2    Glaser, S.3
  • 26
    • 58149380748 scopus 로고    scopus 로고
    • Stable transduction of quiescent T cells without induction of cycle progression by a novel lentiviral vector pseudotyped with measles virus glycoproteins
    • Frecha C, Costa C, Negre D, et al. Stable transduction of quiescent T cells without induction of cycle progression by a novel lentiviral vector pseudotyped with measles virus glycoproteins. Blood. 2008;112(13):4843-4852.
    • (2008) Blood , vol.112 , Issue.13 , pp. 4843-4852
    • Frecha, C.1    Costa, C.2    Negre, D.3
  • 27
    • 78449290135 scopus 로고    scopus 로고
    • CD4+ T-cell help in the tumor milieu is required for recruitment and cytolytic function of CD8+ T lymphocytes
    • Bos R, Sherman LA. CD4+ T-cell help in the tumor milieu is required for recruitment and cytolytic function of CD8+ T lymphocytes. Cancer Res. 2010;70(21):8368-8377.
    • (2010) Cancer Res , vol.70 , Issue.21 , pp. 8368-8377
    • Bos, R.1    Sherman, L.A.2
  • 28
    • 68049118838 scopus 로고    scopus 로고
    • Immunity to murine prostatic tumors: Continuous provision of T-cell help prevents CD8 T-cell tolerance and activates tumor-infiltrating dendritic cells
    • Shafer-Weaver KA, Watkins SK, Anderson MJ, et al. Immunity to murine prostatic tumors: continuous provision of T-cell help prevents CD8 T-cell tolerance and activates tumor-infiltrating dendritic cells. Cancer Res. 2009;69(15):6256-6264.
    • (2009) Cancer Res , vol.69 , Issue.15 , pp. 6256-6264
    • Shafer-Weaver, K.A.1    Watkins, S.K.2    Anderson, M.J.3
  • 29
    • 0034541167 scopus 로고    scopus 로고
    • Tumorspecific CD4+ T cells have a major "post-licensing" role in CTL mediated antitumor immunity
    • Marzo AL, Kinnear BF, Lake RA, et al. Tumorspecific CD4+ T cells have a major "post-licensing" role in CTL mediated antitumor immunity. J Immunol. 2000;165(11):6047-6055.
    • (2000) J Immunol , vol.165 , Issue.11 , pp. 6047-6055
    • Marzo, A.L.1    Kinnear, B.F.2    Lake, R.A.3
  • 30
    • 79960543314 scopus 로고    scopus 로고
    • Anti-CD8 antibodies can trigger CD8 T cell effector function in the absence of TCR engagement and improve peptide-MHCI tetramer staining
    • Clement M, Ladell K, Ekeruche-Makinde J, et al. Anti-CD8 antibodies can trigger CD8 T cell effector function in the absence of TCR engagement and improve peptide-MHCI tetramer staining. J Immunol. 2011;187(2):654-663.
    • (2011) J Immunol , vol.187 , Issue.2 , pp. 654-663
    • Clement, M.1    Ladell, K.2    Ekeruche-Makinde, J.3
  • 31
    • 56249110631 scopus 로고    scopus 로고
    • Interferon-gamma and interleukin-4 reciprocally regulate CD8 expression in CD8+ T cells
    • Apte SH, Baz A, Groves P, Kelso A, Kienzle N. Interferon-gamma and interleukin-4 reciprocally regulate CD8 expression in CD8+ T cells. Proc Natl Acad Sci U S A. 2008;105(45):17475-17480.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.45 , pp. 17475-17480
    • Apte, S.H.1    Baz, A.2    Groves, P.3    Kelso, A.4    Kienzle, N.5
  • 32
    • 77953479708 scopus 로고    scopus 로고
    • Generation of multi-functional antigen-specific human T-cells by lentiviral TCR gene transfer
    • Perro M, Tsang J, Xue SA, et al. Generation of multi-functional antigen-specific human T-cells by lentiviral TCR gene transfer. Gene Ther. 2010; 17(6):721-732.
    • (2010) Gene Ther , vol.17 , Issue.6 , pp. 721-732
    • Perro, M.1    Tsang, J.2    Xue, S.A.3
  • 33
    • 0037443424 scopus 로고    scopus 로고
    • IL-7 surface-engineered lentiviral vectors promote survival and efficient gene transfer in resting primary T lymphocytes
    • DOI 10.1182/blood-2002-07-2224
    • Verhoeyen E, Dardalhon V, Ducrey-Rundquist O, Trono D, Taylor N, Cosset FL. IL-7 surface-engineered lentiviral vectors promote survival and efficient gene transfer in resting primary T lymphocytes. Blood. 2003;101(6):2167-2174. (Pubitemid 36302054)
    • (2003) Blood , vol.101 , Issue.6 , pp. 2167-2174
    • Verhoeyen, E.1    Dardalhon, V.2    Ducrey-Rundquist, O.3    Trono, D.4    Taylor, N.5    Cosset, F.-L.6
  • 34
    • 19344375031 scopus 로고    scopus 로고
    • Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences
    • Mitchell RS, Beitzel BF, Schroder AR, et al. Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences. PLoS Biol. 2004; 2(8):E234.
    • (2004) PLoS Biol , vol.2 , Issue.8
    • Mitchell, R.S.1    Beitzel, B.F.2    Schroder, A.R.3
  • 35
    • 77349100571 scopus 로고    scopus 로고
    • The CD8+ dendritic cell subset
    • Shortman K, Heath WR. The CD8+ dendritic cell subset. Immunol Rev. 2010;234(1):18-31.
    • (2010) Immunol Rev , vol.234 , Issue.1 , pp. 18-31
    • Shortman, K.1    Heath, W.R.2
  • 39
    • 0035980059 scopus 로고    scopus 로고
    • The human CD8 coreceptor effects cytotoxic T cell activation and antigen sensitivity primarily by mediating complete phosphorylation of the T cell receptor zeta chain
    • Purbhoo MA, Boulter JM, Price DA, et al. The human CD8 coreceptor effects cytotoxic T cell activation and antigen sensitivity primarily by mediating complete phosphorylation of the T cell receptor zeta chain. J Biol Chem. 2001;276(35):32786-32792.
    • (2001) J Biol Chem , vol.276 , Issue.35 , pp. 32786-32792
    • Purbhoo, M.A.1    Boulter, J.M.2    Price, D.A.3
  • 40
    • 79955549816 scopus 로고    scopus 로고
    • Opposite effects of endogenous peptide-MHC class I on T cell activity in the presence and absence of CD8
    • Stone JD, Aggen DH, Chervin AS, et al. Opposite effects of endogenous peptide-MHC class I on T cell activity in the presence and absence of CD8. J Immunol. 2011;186(9):5193-5200.
    • (2011) J Immunol , vol.186 , Issue.9 , pp. 5193-5200
    • Stone, J.D.1    Aggen, D.H.2    Chervin, A.S.3
  • 41
    • 35748979154 scopus 로고    scopus 로고
    • Detuning CD8 T cells: Down-regulation of CD8 expression, tetramer binding, and response during CTL activation
    • DOI 10.1084/jem.20062376
    • Xiao Z, Mescher MF, Jameson SC. Detuning CD8 T cells: down-regulation of CD8 expression, tetramer binding, and response during CTL activation. J Exp Med. 2007;204(11):2667-2677. (Pubitemid 350044790)
    • (2007) Journal of Experimental Medicine , vol.204 , Issue.11 , pp. 2667-2677
    • Xiao, Z.1    Mescher, M.F.2    Jameson, S.C.3
  • 43
    • 11844263392 scopus 로고    scopus 로고
    • Peripheral "CD8 tuning" dynamically modulates the size and responsiveness of an antigen-specific T cell pool in vivo
    • Maile R, Siler CA, Kerry SE, Midkiff KE, Collins EJ, Frelinger JA. Peripheral "CD8 tuning" dynamically modulates the size and responsiveness of an antigen-specific T cell pool in vivo. J Immunol. 2005; 174(2):619-627. (Pubitemid 40094253)
    • (2005) Journal of Immunology , vol.174 , Issue.2 , pp. 619-627
    • Maile, R.1    Siler, C.A.2    Kerry, S.E.3    Midkiff, K.E.4    Collins, E.J.5    Frelinger, J.A.6
  • 44
    • 0037083486 scopus 로고    scopus 로고
    • A clonal culture system demonstrates that IL-4 induces a subpopulation of noncytolytic T cells with low CD8, perforin, and granzyme expression
    • Kienzle N, Buttigieg K, Groves P, Kawula T, Kelso A. A clonal culture system demonstrates that IL-4 induces a subpopulation of noncytolytic T cells with low CD8, perforin, and granzyme expression. J Immunol. 2002;168(4):1672- 1681. (Pubitemid 34135763)
    • (2002) Journal of Immunology , vol.168 , Issue.4 , pp. 1672-1681
    • Kienzle, N.1    Buttigieg, K.2    Groves, P.3    Kawula, T.4    Kelso, A.5
  • 45
    • 33745203490 scopus 로고    scopus 로고
    • Distribution and three-dimensional structure of AIDS virus envelope spikes
    • Zhu P, Liu J, Bess J Jr, et al. Distribution and three-dimensional structure of AIDS virus envelope spikes. Nature. 2006;441(7095):847-852.
    • (2006) Nature , vol.441 , Issue.7095 , pp. 847-852
    • Zhu, P.1    Liu, J.2    Bess Jr., J.3
  • 47
    • 38449094082 scopus 로고    scopus 로고
    • Targeting the Wilms tumor antigen 1 by TCR gene transfer: TCR variants improve tetramer binding but not the function of gene modified human T cells
    • Thomas S, Xue SA, Cesco-Gaspere M, et al. Targeting the Wilms tumor antigen 1 by TCR gene transfer: TCR variants improve tetramer binding but not the function of gene modified human T cells. J Immunol. 2007;179(9):5803-5810.
    • (2007) J Immunol , vol.179 , Issue.9 , pp. 5803-5810
    • Thomas, S.1    Xue, S.A.2    Cesco-Gaspere, M.3
  • 48
    • 67650581553 scopus 로고    scopus 로고
    • Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity
    • Almeida JR, Sauce D, Price DA, et al. Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity. Blood. 2009;113(25):6351-6360.
    • (2009) Blood , vol.113 , Issue.25 , pp. 6351-6360
    • Almeida, J.R.1    Sauce, D.2    Price, D.A.3
  • 49
    • 80555148949 scopus 로고    scopus 로고
    • A high-throughput single-cell analysis of human CD8 T cell functions reveals discordance for cytokine secretion and cytolysis
    • Varadarajan N, Julg B, Yamanaka YJ, et al. A high-throughput single-cell analysis of human CD8 T cell functions reveals discordance for cytokine secretion and cytolysis. J Clin Invest. 2011;121(11):4322-4331.
    • (2011) J Clin Invest , vol.121 , Issue.11 , pp. 4322-4331
    • Varadarajan, N.1    Julg, B.2    Yamanaka, Y.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.