메뉴 건너뛰기




Volumn 184, Issue 3, 2010, Pages 1617-1629

A single TCRα-chain with dominant peptide recognition in the allorestricted HER2/neu-specific T cell repertoire

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; ALLOANTIGEN; EPITOPE; HER2 PROTEIN, HUMAN; HLA A2 ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR; PEPTIDE FRAGMENT;

EID: 77949325014     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0902155     Document Type: Article
Times cited : (26)

References (58)
  • 4
    • 0029826486 scopus 로고    scopus 로고
    • Peptide-specific cytotoxic T lymphocytes restricted by nonself major histocompatibility complex class Imolecules: Reagents for tumor immunotherapy
    • Sadovnikova, E., and H. J. Stauss. 1996. Peptide-specific cytotoxic T lymphocytes restricted by nonself major histocompatibility complex class Imolecules: reagents for tumor immunotherapy. Proc. Natl. Acad. Sci. USA 93: 13114-13118.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 13114-13118
    • Sadovnikova, E.1    Stauss, H.J.2
  • 6
    • 0028931032 scopus 로고
    • The T cell response of HLA-DR transgenic mice to human myelin basic protein and other antigens in the presence and absence of human CD4
    • Altmann, D. M., D. C. Douek, A. J. Frater, C. M. Hetherington, H. Inoko, and J. I. Elliott. 1995. The T cell response of HLA-DR transgenic mice to human myelin basic protein and other antigens in the presence and absence of human CD4. J. Exp. Med. 181: 867-875.
    • (1995) J. Exp. Med. , vol.181 , pp. 867-875
    • Altmann, D.M.1    Douek, D.C.2    Frater, A.J.3    Hetherington, C.M.4    Inoko, H.5    Elliott, J.I.6
  • 7
    • 0036635506 scopus 로고    scopus 로고
    • T-cell-receptor gene therapy
    • Schumacher, T. N. 2002. T-cell-receptor gene therapy. Nat. Rev. Immunol. 2: 512-519.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 512-519
    • Schumacher, T.N.1
  • 8
    • 35548977173 scopus 로고    scopus 로고
    • Allorestricted T cells with specificity for the FMNL1-derived peptide PP2 have potent antitumor activity against hematologic and other malignancies
    • Schuster, I. G., D. H. Busch, E. Eppinger, E. Kremmer, S. Milosevic, C. Hennard, C. Kuttler, J. W. Ellwart, B. Frankenberger, E. Nössner, et al. 2007. Allorestricted T cells with specificity for the FMNL1-derived peptide PP2 have potent antitumor activity against hematologic and other malignancies. Blood 110: 2931-2939.
    • (2007) Blood , vol.110 , pp. 2931-2939
    • Schuster, I.G.1    Busch, D.H.2    Eppinger, E.3    Kremmer, E.4    Milosevic, S.5    Hennard, C.6    Kuttler, C.7    Ellwart, J.W.8    Frankenberger, B.9    Nössner, E.10
  • 9
    • 55849126233 scopus 로고    scopus 로고
    • Signal integration: A framework for understanding the efficacy of therapeutics targeting the human EGFR family
    • Shepard, H. M., C. M. Brdlik, and H. Schreiber. 2008. Signal integration: a framework for understanding the efficacy of therapeutics targeting the human EGFR family. J. Clin. Invest. 118: 3574-3581.
    • (2008) J. Clin. Invest. , vol.118 , pp. 3574-3581
    • Shepard, H.M.1    Brdlik, C.M.2    Schreiber, H.3
  • 10
    • 0029150504 scopus 로고
    • The receptor tyrosine kinase p185HER2 is expressed on a subset of B-lymphoid blasts from patients with acute lymphoblastic leukemia and chronic myelogenous leukemia
    • Bühring, H. J., I. Sures, B. Jallal, F. U. Weiss, F. W. Busch, W. D. Ludwig, R. Handgretinger, H. D. Waller, and A. Ullrich. 1995. The receptor tyrosine kinase p185HER2 is expressed on a subset of B-lymphoid blasts from patients with acute lymphoblastic leukemia and chronic myelogenous leukemia. Blood 86: 1916-1923.
    • (1995) Blood , vol.86 , pp. 1916-1923
    • Bühring, H.J.1    Sures, I.2    Jallal, B.3    Weiss, F.U.4    Busch, F.W.5    Ludwig, W.D.6    Handgretinger, R.7    Waller, H.D.8    Ullrich, A.9
  • 11
    • 0025879780 scopus 로고
    • Endogenously synthesized peptide with an endoplasmic reticulum signal sequence sensitizes antigen processing mutant cells to class I-restricted cell-mediated lysis
    • Anderson, K., P. Cresswell, M. Gammon, J. Hermes, A. Williamson, and H. Zweerink. 1991. Endogenously synthesized peptide with an endoplasmic reticulum signal sequence sensitizes antigen processing mutant cells to class I-restricted cell-mediated lysis. J. Exp. Med. 174: 489-492.
    • (1991) J. Exp. Med. , vol.174 , pp. 489-492
    • Anderson, K.1    Cresswell, P.2    Gammon, M.3    Hermes, J.4    Williamson, A.5    Zweerink, H.6
  • 12
    • 0026576422 scopus 로고
    • HLA-A2 molecules in an antigen-processing mutant cell contain signal sequence-derived peptides
    • Wei, M. L., and P. Cresswell. 1992. HLA-A2 molecules in an antigen-processing mutant cell contain signal sequence-derived peptides. Nature 356: 443-446.
    • (1992) Nature , vol.356 , pp. 443-446
    • Wei, M.L.1    Cresswell, P.2
  • 13
    • 0142054390 scopus 로고    scopus 로고
    • Redirection of antileukemic reactivity of peripheral T lymphocytes using gene transfer of minor histocompatibility antigen HA-2-specific T-cell receptor complexes expressing a conserved a joining region
    • Heemskerk, M. H., M. Hoogeboom, R. A. de Paus, M. G. Kester, M. A. van der Hoorn, E. Goulmy, R. Willemze, and J. H. Falkenburg. 2003. Redirection of antileukemic reactivity of peripheral T lymphocytes using gene transfer of minor histocompatibility antigen HA-2-specific T-cell receptor complexes expressing a conserved a joining region. Blood 102: 3530-3540.
    • (2003) Blood , vol.102 , pp. 3530-3540
    • Heemskerk, M.H.1    Hoogeboom, M.2    De Paus, R.A.3    Kester, M.G.4    Van Der Hoorn, M.A.5    Goulmy, E.6    Willemze, R.7    Falkenburg, J.H.8
  • 16
    • 0033565301 scopus 로고    scopus 로고
    • Identification of new HER2/neu-derived peptide epitopes that can elicit specific CTL against autologous and allogeneic carcinomas and melanomas
    • Rongcun, Y., F. Salazar-Onfray, J. Charo, K. J. Malmberg, K. Evrin, H. Maes, K. Kono, C. Hising, M. Petersson, O. Larsson, et al. 1999. Identification of new HER2/neu-derived peptide epitopes that can elicit specific CTL against autologous and allogeneic carcinomas and melanomas. J. Immunol. 163: 1037-1044.
    • (1999) J. Immunol. , vol.163 , pp. 1037-1044
    • Rongcun, Y.1    Salazar-Onfray, F.2    Charo, J.3    Malmberg, K.J.4    Evrin, K.5    Maes, H.6    Kono, K.7    Hising, C.8    Petersson, M.9    Larsson, O.10
  • 17
    • 0029053749 scopus 로고
    • Identification of an immunodominant peptide of HER-2/neu protooncogene recognized by ovarian tumor-specific cytotoxic T lymphocyte lines
    • Fisk, B., T. L. Blevins, J. T. Wharton, and C. G. Ioannides. 1995. Identification of an immunodominant peptide of HER-2/neu protooncogene recognized by ovarian tumor-specific cytotoxic T lymphocyte lines. J. Exp. Med. 181: 2109-2117.
    • (1995) J. Exp. Med. , vol.181 , pp. 2109-2117
    • Fisk, B.1    Blevins, T.L.2    Wharton, J.T.3    Ioannides, C.G.4
  • 18
    • 0026560192 scopus 로고
    • Identification of the nonamer peptide from influenza A matrix protein and the role of pockets of HLA-A2 in its recognition by cytotoxic T lymphocytes
    • Morrison, J., J. Elvin, F. Latron, F. Gotch, R. Moots, J. L. Strominger, and A. McMichael. 1992. Identification of the nonamer peptide from influenza A matrix protein and the role of pockets of HLA-A2 in its recognition by cytotoxic T lymphocytes. Eur. J. Immunol. 22: 903-907.
    • (1992) Eur. J. Immunol , vol.22 , pp. 903-907
    • Morrison, J.1    Elvin, J.2    Latron, F.3    Gotch, F.4    Moots, R.5    Strominger, J.L.6    McMichael, A.7
  • 19
    • 0001433072 scopus 로고    scopus 로고
    • An HLA-A2-restricted tyrosinase antigen on melanoma cells results from posttranslational modification and suggests a novel pathway for processing of membrane proteins
    • Skipper, J. C., R. C. Hendrickson, P. H. Gulden, V. Brichard, A. Van Pel, Y. Chen, J. Shabanowitz, T. Wolfel, C. L. Slingluff, Jr., T. Boon, et al. 1996. An HLA-A2-restricted tyrosinase antigen on melanoma cells results from posttranslational modification and suggests a novel pathway for processing of membrane proteins. J. Exp. Med. 183: 527-534.
    • (1996) J. Exp. Med. , vol.183 , pp. 527-534
    • Skipper, J.C.1    Hendrickson, R.C.2    Gulden, P.H.3    Brichard, V.4    Van Pel, A.5    Chen, Y.6    Shabanowitz, J.7    Wolfel, T.8    Slingluff Jr., C.L.9    Boon, T.10
  • 20
    • 0030587077 scopus 로고    scopus 로고
    • Improved induction of melanoma-reactive CTL with peptides from the melanoma antigen gp100 modified at HLA-A*0201-binding residues
    • Parkhurst, M. R., M. L. Salgaller, S. Southwood, P. F. Robbins, A. Sette, S. A. Rosenberg, and Y. Kawakami. 1996. Improved induction of melanoma-reactive CTL with peptides from the melanoma antigen gp100 modified at HLA-A*0201-binding residues. J. Immunol. 157: 2539-2548.
    • (1996) J. Immunol. , vol.157 , pp. 2539-2548
    • Parkhurst, M.R.1    Salgaller, M.L.2    Southwood, S.3    Robbins, P.F.4    Sette, A.5    Rosenberg, S.A.6    Kawakami, Y.7
  • 21
    • 0030928128 scopus 로고    scopus 로고
    • Development of a candidate HLA Ap0201 restricted peptide-based vaccine against human cytomegalovirus infection
    • Diamond, D. J., J. York, J. Y. Sun, C. L. Wright, and S. J. Forman. 1997. Development of a candidate HLA Ap0201 restricted peptide-based vaccine against human cytomegalovirus infection. Blood 90: 1751-1767.
    • (1997) Blood , vol.90 , pp. 1751-1767
    • Diamond, D.J.1    York, J.2    Sun, J.Y.3    Wright, C.L.4    Forman, S.J.5
  • 22
    • 0032033695 scopus 로고    scopus 로고
    • Coordinate regulation of complex T cell populations responding to bacterial infection
    • Busch, D. H., I. M. Pilip, S. Vijh, and E. G. Pamer. 1998. Coordinate regulation of complex T cell populations responding to bacterial infection. Immunity 8: 353-362.
    • (1998) Immunity , vol.8 , pp. 353-362
    • Busch, D.H.1    Pilip, I.M.2    Vijh, S.3    Pamer, E.G.4
  • 24
    • 0033118739 scopus 로고    scopus 로고
    • A kinetic basis for T cell receptor repertoire selection during an immune response
    • Savage, P. A., J. J. Boniface, and M. M. Davis. 1999. A kinetic basis for T cell receptor repertoire selection during an immune response. Immunity 10: 485-492.
    • (1999) Immunity , vol.10 , pp. 485-492
    • Savage, P.A.1    Boniface, J.J.2    Davis, M.M.3
  • 25
    • 0024362404 scopus 로고
    • Analysis of T cell receptor transcripts using the polymerase chain reaction
    • Roth, M. E., M. J. Lacy, L. K. McNeil, and D. M. Kranz. 1989. Analysis of T cell receptor transcripts using the polymerase chain reaction. Biotechniques 7: 746-754.
    • (1989) Biotechniques , vol.7 , pp. 746-754
    • Roth, M.E.1    Lacy, M.J.2    McNeil, L.K.3    Kranz, D.M.4
  • 26
    • 0037208270 scopus 로고    scopus 로고
    • IMGT databases, web resources and tools for immunoglobulin and T cell receptor sequence analysis
    • Lefranc, M. P. 2003. IMGT databases, web resources and tools for immunoglobulin and T cell receptor sequence analysis, http://imgt.cines.fr. Leukemia 17: 260-266.
    • (2003) Leukemia , vol.17 , pp. 260-266
    • Lefranc, M.P.1
  • 28
    • 33749005425 scopus 로고    scopus 로고
    • Enhanced antitumor activity of murine-human hybrid T-cell receptor (TCR) in human lymphocytes is associated with improved pairing and TCR/CD3 stability
    • Cohen, C. J., Y. Zhao, Z. Zheng, S. A. Rosenberg, and R. A. Morgan. 2006. Enhanced antitumor activity of murine-human hybrid T-cell receptor (TCR) in human lymphocytes is associated with improved pairing and TCR/CD3 stability. Cancer Res. 66: 8878-8886.
    • (2006) Cancer Res. , vol.66 , pp. 8878-8886
    • Cohen, C.J.1    Zhao, Y.2    Zheng, Z.3    Rosenberg, S.A.4    Morgan, R.A.5
  • 32
  • 33
    • 0042834246 scopus 로고    scopus 로고
    • High efficiency TCR gene transfer into primary human lymphocytes affords avid recognition of melanoma tumor antigen glycoprotein 100 and does not alter the recognition of autologous melanoma antigens
    • Morgan, R. A., M. E. Dudley, Y. Y. Yu, Z. Zheng, P. F. Robbins, M. R. Theoret, J. R. Wunderlich, M. S. Hughes, N. P. Restifo, and S. A. Rosenberg. 2003. High efficiency TCR gene transfer into primary human lymphocytes affords avid recognition of melanoma tumor antigen glycoprotein 100 and does not alter the recognition of autologous melanoma antigens. J. Immunol. 171: 3287-3295.
    • (2003) J. Immunol. , vol.171 , pp. 3287-3295
    • Morgan, R.A.1    Dudley, M.E.2    Yu, Y.Y.3    Zheng, Z.4    Robbins, P.F.5    Theoret, M.R.6    Wunderlich, J.R.7    Hughes, M.S.8    Restifo, N.P.9    Rosenberg, S.A.10
  • 34
    • 0027199885 scopus 로고
    • T cell receptor (TCR) structure of autologous melanoma-reactive cytotoxic T lymphocyte (CTL) clones: Tumor-infiltrating lymphocytes overexpress in vivo the TCR β chain sequence used by an HLA-A2-restricted and melanocyte-lineage-specific CTL clone
    • Sensi, M., S. Salvi, C. Castelli, C. Maccalli, A. Mazzocchi, R. Mortarini, G. Nicolini, M. Herlyn, G. Parmiani, and A. Anichini. 1993. T cell receptor (TCR) structure of autologous melanoma-reactive cytotoxic T lymphocyte (CTL) clones: tumor-infiltrating lymphocytes overexpress in vivo the TCR β chain sequence used by an HLA-A2-restricted and melanocyte-lineage-specific CTL clone. J. Exp. Med. 178: 1231-1246.
    • (1993) J. Exp. Med. , vol.178 , pp. 1231-1246
    • Sensi, M.1    Salvi, S.2    Castelli, C.3    Maccalli, C.4    Mazzocchi, A.5    Mortarini, R.6    Nicolini, G.7    Herlyn, M.8    Parmiani, G.9    Anichini, A.10
  • 37
    • 34248595961 scopus 로고    scopus 로고
    • Enhanced antitumor activity of T cells engineered to express T-cell receptors with a second disulfide bond
    • Cohen, C. J., Y. F. Li, M. El-Gamil, P. F. Robbins, S. A. Rosenberg, and R. A. Morgan. 2007. Enhanced antitumor activity of T cells engineered to express T-cell receptors with a second disulfide bond. Cancer Res. 67: 3898-3903.
    • (2007) Cancer Res. , vol.67 , pp. 3898-3903
    • Cohen, C.J.1    Li, Y.F.2    El-Gamil, M.3    Robbins, P.F.4    Rosenberg, S.A.5    Morgan, R.A.6
  • 42
    • 14844341146 scopus 로고
    • Recognition of multiple epitopes in the human melanoma antigen gp100 by tumor-infiltrating T lymphocytes associated with in vivo tumor regression
    • Kawakami, Y., S. Eliyahu, C. Jennings, K. Sakaguchi, X. Kang, S. Southwood, P. F. Robbins, A. Sette, E. Appella, and S. A. Rosenberg. 1995. Recognition of multiple epitopes in the human melanoma antigen gp100 by tumor-infiltrating T lymphocytes associated with in vivo tumor regression. J. Immunol. 154: 3961-3968.
    • (1995) J. Immunol. , vol.154 , pp. 3961-3968
    • Kawakami, Y.1    Eliyahu, S.2    Jennings, C.3    Sakaguchi, K.4    Kang, X.5    Southwood, S.6    Robbins, P.F.7    Sette, A.8    Appella, E.9    Rosenberg, S.A.10
  • 43
    • 0027304399 scopus 로고
    • Prominent role of secondary anchor residues in peptide binding to HLA- A2.1 molecules
    • DOI 10.1016/0092-8674(93)90472-3
    • Ruppert, J., J. Sidney, E. Celis, R. T. Kubo, H. M. Grey, and A. Sette. 1993. Prominent role of secondary anchor residues in peptide binding to HLA-A2.1 molecules. Cell 74: 929-937. (Pubitemid 23270612)
    • (1993) Cell , vol.74 , Issue.5 , pp. 929-937
    • Ruppert, J.1    Sidney, J.2    Celis, E.3    Kubo, R.T.4    Grey, H.M.5    Sette, A.6
  • 46
    • 38649127824 scopus 로고    scopus 로고
    • A safeguard eliminates T cell receptor gene-modified autoreactive T cells after adoptive transfer
    • Kieback, E., J. Charo, D. Sommermeyer, T. Blankenstein, and W. Uckert. 2008. A safeguard eliminates T cell receptor gene-modified autoreactive T cells after adoptive transfer. Proc. Natl. Acad. Sci. USA 105: 623-628.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 623-628
    • Kieback, E.1    Charo, J.2    Sommermeyer, D.3    Blankenstein, T.4    Uckert, W.5
  • 48
    • 0033579435 scopus 로고    scopus 로고
    • Poor binding of a HER-2/neu epitope (GP2) to HLA-A2.1 is due to a lack of interactions with the center of the peptide
    • Kuhns, J. J., M. A. Batalia, S. Yan, and E. J. Collins. 1999. Poor binding of a HER-2/neu epitope (GP2) to HLA-A2.1 is due to a lack of interactions with the center of the peptide. J. Biol. Chem. 274: 36422-36427.
    • (1999) J. Biol. Chem. , vol.274 , pp. 36422-36427
    • Kuhns, J.J.1    Batalia, M.A.2    Yan, S.3    Collins, E.J.4
  • 50
    • 61349186956 scopus 로고    scopus 로고
    • HER-2/neu mediated down-regulation of MHC class I antigen processing prevents CTL-mediated tumor recognition upon DNA vaccination in HLA-A2 transgenic mice
    • Vertuani, S., C. Triulzi, A. K. Roos, J. Charo, H. Norell, F. Lemonnier, P. Pisa, B. Seliger, and R. Kiessling. 2009. HER-2/neu mediated down-regulation of MHC class I antigen processing prevents CTL-mediated tumor recognition upon DNA vaccination in HLA-A2 transgenic mice. Cancer Immunol. Immunother. 58: 653-664.
    • (2009) Cancer Immunol. Immunother. , vol.58 , pp. 653-664
    • Vertuani, S.1    Triulzi, C.2    Roos, A.K.3    Charo, J.4    Norell, H.5    Lemonnier, F.6    Pisa, P.7    Seliger, B.8    Kiessling, R.9
  • 51
    • 0037089649 scopus 로고    scopus 로고
    • Predominant role of T cell receptor (TCR)-α chain in forming preimmune TCR repertoire revealed by clonal TCR reconstitution system
    • Yokosuka, T., K. Takase, M. Suzuki, Y. Nakagawa, S. Taki, H. Takahashi, T. Fujisawa, H. Arase, and T. Saito. 2002. Predominant role of T cell receptor (TCR)-α chain in forming preimmune TCR repertoire revealed by clonal TCR reconstitution system. J. Exp. Med. 195: 991-1001.
    • (2002) J. Exp. Med. , vol.195 , pp. 991-1001
    • Yokosuka, T.1    Takase, K.2    Suzuki, M.3    Nakagawa, Y.4    Taki, S.5    Takahashi, H.6    Fujisawa, T.7    Arase, H.8    Saito, T.9
  • 52
    • 0022997960 scopus 로고
    • The T cell repertoire may be biased in favor of MHC recognition
    • Blackman, M., J. Yagüe, R. Kubo, D. Gay, C. Coleclough, E. Palmer, J. Kappler, and P. Marrack. 1986. The T cell repertoire may be biased in favor of MHC recognition. Cell 47: 349-357. (Pubitemid 17210149)
    • (1986) Cell , vol.47 , Issue.3 , pp. 349-357
    • Blackman, M.1    Yague, J.2    Kubo, R.3
  • 54
    • 12444298109 scopus 로고    scopus 로고
    • Structure of an autoimmune T cell receptor complexed with class II peptide-MHC: Insights into MHC bias and antigen specificity
    • DOI 10.1016/j.immuni.2004.11.015, PII S1074761304003784
    • Maynard, J., K. Petersson, D. H. Wilson, E. J. Adams, S. E. Blondelle, M. J. Boulanger, D. B. Wilson, and K. C. Garcia. 2005. Structure of an autoimmune T cell receptor complexed with class II peptide-MHC: insights into MHC bias and antigen specificity. Immunity 22: 81-92. (Pubitemid 40143453)
    • (2005) Immunity , vol.22 , Issue.1 , pp. 81-92
    • Maynard, J.1    Petersson, K.2    Wilson, D.H.3    Adams, E.J.4    Blondelle, S.E.5    Boulanger, M.J.6    Wilson, D.B.7    Garcia, K.C.8
  • 55
    • 34548128306 scopus 로고    scopus 로고
    • Structural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon'
    • Feng, D., C. J. Bond, L. K. Ely, J. Maynard, and K. C. Garcia. 2007. Structural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon'. Nat. Immunol. 8: 975-983.
    • (2007) Nat. Immunol. , vol.8 , pp. 975-983
    • Feng, D.1    Bond, C.J.2    Ely, L.K.3    Maynard, J.4    Garcia, K.C.5
  • 57
    • 0037234768 scopus 로고    scopus 로고
    • TCRs with high affinity for foreign pMHC show self-reactivity
    • Holler, P. D., L. K. Chlewicki, and D. M. Kranz. 2003. TCRs with high affinity for foreign pMHC show self-reactivity. Nat. Immunol. 4: 55-62.
    • (2003) Nat. Immunol. , vol.4 , pp. 55-62
    • Holler, P.D.1    Chlewicki, L.K.2    Kranz, D.M.3
  • 58
    • 70249091519 scopus 로고    scopus 로고
    • The impact of TCR-binding properties and antigen presentation format on T cell responsiveness
    • Chervin, A. S., J. D. Stone, P. D. Holler, A. Bai, J. Chen, H. N. Eisen, and D. M. Kranz. 2009. The impact of TCR-binding properties and antigen presentation format on T cell responsiveness. J. Immunol. 183: 1166-1178.
    • (2009) J. Immunol. , vol.183 , pp. 1166-1178
    • Chervin, A.S.1    Stone, J.D.2    Holler, P.D.3    Bai, A.4    Chen, J.5    Eisen, H.N.6    Kranz, D.M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.